BR9600975A - Derivados do ácido gem-difluorfenilacético e de gem-difluorfenilacetamida processo de sua preparação e suas aplicações farmacêuticas - Google Patents
Derivados do ácido gem-difluorfenilacético e de gem-difluorfenilacetamida processo de sua preparação e suas aplicações farmacêuticasInfo
- Publication number
- BR9600975A BR9600975A BR9600975A BR9600975A BR9600975A BR 9600975 A BR9600975 A BR 9600975A BR 9600975 A BR9600975 A BR 9600975A BR 9600975 A BR9600975 A BR 9600975A BR 9600975 A BR9600975 A BR 9600975A
- Authority
- BR
- Brazil
- Prior art keywords
- gem
- difluorphenylacetic
- difluorphenylacetamide
- derivatives
- preparation
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/53—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/54—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/81—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BR9600975A BR9600975A (pt) | 1996-03-11 | 1996-03-11 | Derivados do ácido gem-difluorfenilacético e de gem-difluorfenilacetamida processo de sua preparação e suas aplicações farmacêuticas |
GB9605407A GB2311066B (en) | 1996-03-11 | 1996-03-14 | Novel gem-difluoro derivatives of phenylacetamide and phenylacetic acid and their pharmaceutical uses |
ES009600651A ES2130923B1 (es) | 1996-03-11 | 1996-03-15 | Nuevos derivados gem-difluoro de la fenilacetamida y del acido fenilacetico y sus usos farmaceuticos. |
IT96MI000505A IT1283256B1 (it) | 1996-03-11 | 1996-03-15 | Derivati gem-difluoro di fenilacetammide e di acido fenilacetico e loro usi farmaceutici |
JP05892596A JP3947242B2 (ja) | 1996-03-11 | 1996-03-15 | フェニルアセトアミドおよびフェニル酢酸の新規のgem−ジフルオロ誘導体並びにそれらの薬学的使用 |
BE9600228A BE1010031A5 (fr) | 1996-03-11 | 1996-03-15 | Derives gem-difluoro de phenylacetamide et d'acide phenylacetique, leur preparation et leurs utilisations. |
DE19610357A DE19610357C2 (de) | 1996-03-11 | 1996-03-15 | Geminale Difluorderivate von Phenylacetamid und Phenylessigsäure, Verfahren zu deren Herstellung sowie deren pharmazeutische Zusammensetzungen |
FR9603314A FR2745810B1 (fr) | 1996-03-11 | 1996-03-15 | Nouveaux composes gem-difluoro d'acide phenylacetique et de phenylacetamide, utiles comme medicaments anti-inflammatoires et anti-rhumatismaux, et procede de fabrication |
CH00782/96A CH690722A5 (fr) | 1996-03-11 | 1996-03-26 | Dérivés gem-Difluoro du phénylacétamide et de l'acide phénylacétique et leurs utilisations pharmaceutiques. |
CN96108142A CN1101806C (zh) | 1996-03-11 | 1996-06-10 | 苯乙酰胺和苯乙酸的新偕二氟衍生物及其药物学应用 |
US08/710,399 US6034266A (en) | 1996-03-11 | 1996-09-17 | Gem-difluoro derivative of phenylacetamide and phenylacetic acid and their pharmaceutical uses |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BR9600975A BR9600975A (pt) | 1996-03-11 | 1996-03-11 | Derivados do ácido gem-difluorfenilacético e de gem-difluorfenilacetamida processo de sua preparação e suas aplicações farmacêuticas |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9600975A true BR9600975A (pt) | 1997-12-30 |
Family
ID=38353109
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9600975A BR9600975A (pt) | 1996-03-11 | 1996-03-11 | Derivados do ácido gem-difluorfenilacético e de gem-difluorfenilacetamida processo de sua preparação e suas aplicações farmacêuticas |
Country Status (10)
Country | Link |
---|---|
JP (1) | JP3947242B2 (pt) |
CN (1) | CN1101806C (pt) |
BE (1) | BE1010031A5 (pt) |
BR (1) | BR9600975A (pt) |
CH (1) | CH690722A5 (pt) |
DE (1) | DE19610357C2 (pt) |
ES (1) | ES2130923B1 (pt) |
FR (1) | FR2745810B1 (pt) |
GB (1) | GB2311066B (pt) |
IT (1) | IT1283256B1 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9922830D0 (en) | 1999-09-27 | 1999-11-24 | Novartis Ag | Processes |
JP5685384B2 (ja) * | 2010-03-29 | 2015-03-18 | 公益財団法人相模中央化学研究所 | 3,3−ジフルオロ−2,3−ジヒドロインドール−2−オン誘導体の製造方法 |
CN108299137B (zh) * | 2018-04-09 | 2020-04-14 | 中南大学 | 一种靛红腙类化合物选择性氟化方法 |
CN113698308A (zh) * | 2021-08-25 | 2021-11-26 | 山东辰龙药业有限公司 | 一种溴芬酸钠新合成方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3895063A (en) * | 1965-04-08 | 1975-07-15 | Ciba Geigy Corp | Substituted Anilino Benzyl Alcohols |
US3558690A (en) * | 1965-04-08 | 1971-01-26 | Gelgy Chemical Corp | Substituted derivatives of 2-anilinophenylacetic acids and a process of preparation |
IL64724A0 (en) * | 1981-02-17 | 1982-03-31 | Robins Co Inc A H | 2-amino-3-(halobenzoyl)-methylphenylacetic acids and esters and salts thereof and pharmaceutical compositions containing them |
US5220064A (en) * | 1986-11-26 | 1993-06-15 | Warner-Lambert Company | Substituted 4'-hydroxyphenylacetic acid derivatives having antiinflammatory and analgesic activity |
-
1996
- 1996-03-11 BR BR9600975A patent/BR9600975A/pt not_active IP Right Cessation
- 1996-03-14 GB GB9605407A patent/GB2311066B/en not_active Expired - Fee Related
- 1996-03-15 IT IT96MI000505A patent/IT1283256B1/it active IP Right Grant
- 1996-03-15 ES ES009600651A patent/ES2130923B1/es not_active Expired - Fee Related
- 1996-03-15 BE BE9600228A patent/BE1010031A5/fr not_active IP Right Cessation
- 1996-03-15 DE DE19610357A patent/DE19610357C2/de not_active Expired - Fee Related
- 1996-03-15 FR FR9603314A patent/FR2745810B1/fr not_active Expired - Fee Related
- 1996-03-15 JP JP05892596A patent/JP3947242B2/ja not_active Expired - Fee Related
- 1996-03-26 CH CH00782/96A patent/CH690722A5/fr not_active IP Right Cessation
- 1996-06-10 CN CN96108142A patent/CN1101806C/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
GB2311066A (en) | 1997-09-17 |
JPH09323962A (ja) | 1997-12-16 |
JP3947242B2 (ja) | 2007-07-18 |
ES2130923A1 (es) | 1999-07-01 |
CN1159443A (zh) | 1997-09-17 |
ITMI960505A0 (pt) | 1996-03-15 |
ES2130923B1 (es) | 2000-01-16 |
FR2745810A1 (fr) | 1997-09-12 |
DE19610357A1 (de) | 1997-09-18 |
BE1010031A5 (fr) | 1997-11-04 |
IT1283256B1 (it) | 1998-04-16 |
CN1101806C (zh) | 2003-02-19 |
FR2745810B1 (fr) | 1998-06-19 |
GB9605407D0 (en) | 1996-05-15 |
GB2311066B (en) | 1999-12-08 |
DE19610357C2 (de) | 1998-08-13 |
CH690722A5 (fr) | 2000-12-29 |
ITMI960505A1 (it) | 1997-09-15 |
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Legal Events
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B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 24/10/2006, OBSERVADAS AS CONDICOES LEGAIS. |
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B24C | Patent annual fee: request for for restoration |
Free format text: REFERENTE 12A. E 15A, E 16A. ANUIDADE(S). |
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B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 2137 DE 20/12/2011 E AO NAO RECOLHIMENTO DA 17A ANUIDADE. |