BR112023005043A2 - Vacina contra covid-19 à base de piv5 - Google Patents
Vacina contra covid-19 à base de piv5Info
- Publication number
- BR112023005043A2 BR112023005043A2 BR112023005043A BR112023005043A BR112023005043A2 BR 112023005043 A2 BR112023005043 A2 BR 112023005043A2 BR 112023005043 A BR112023005043 A BR 112023005043A BR 112023005043 A BR112023005043 A BR 112023005043A BR 112023005043 A2 BR112023005043 A2 BR 112023005043A2
- Authority
- BR
- Brazil
- Prior art keywords
- piv5
- vaccine against
- covid
- against covid
- effective
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18711—Rubulavirus, e.g. mumps virus, parainfluenza 2,4
- C12N2760/18741—Use of virus, viral particle or viral elements as a vector
- C12N2760/18743—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/20011—Coronaviridae
- C12N2770/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/20011—Coronaviridae
- C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Veterinary Medicine (AREA)
- Plant Pathology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
VACINA CONTRA COVID-19 À BASE DE PIV5. A presente invenção refere-se a construtos do vírus da parainfluenza tipo 5 (PIV5) que expressa a proteína spike (S) do envelope de SARS-CoV-2 para uso como vacinas contra COVID seguras, estáveis, eficazes e econômicas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063080862P | 2020-09-21 | 2020-09-21 | |
US202163217361P | 2021-07-01 | 2021-07-01 | |
PCT/US2021/051196 WO2022061264A1 (en) | 2020-09-21 | 2021-09-21 | Piv5-based covid-19 vaccine |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112023005043A2 true BR112023005043A2 (pt) | 2023-04-18 |
Family
ID=80776394
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112023005043A BR112023005043A2 (pt) | 2020-09-21 | 2021-09-21 | Vacina contra covid-19 à base de piv5 |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP4213872A4 (pt) |
JP (1) | JP2023542922A (pt) |
AU (1) | AU2021342576A1 (pt) |
BR (1) | BR112023005043A2 (pt) |
CA (1) | CA3196157A1 (pt) |
MX (1) | MX2023003199A (pt) |
WO (1) | WO2022061264A1 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113005149A (zh) * | 2021-03-26 | 2021-06-22 | 中国农业大学 | 一种表达冠状病毒受体结合域串联二聚体的重组副流感病毒5型载体 |
CN113073116B (zh) * | 2021-04-02 | 2022-11-11 | 中国农业大学 | 一种表达新冠病毒Spike蛋白重组副流感病毒5型制备和应用 |
GB202209861D0 (en) * | 2022-07-05 | 2022-08-17 | Univ Court Univ St Andrews | Viral vectors |
US20240148857A1 (en) * | 2022-11-04 | 2024-05-09 | Blue Lake Biotechnology, Inc. | Recombinant rsv vaccine: methods of making and using the same |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108130345A (zh) * | 2012-01-24 | 2018-06-08 | 乔治亚大学研究基金公司 | 基于副流感病毒5的疫苗 |
US20230105376A1 (en) * | 2021-09-20 | 2023-04-06 | Cyanvac Llc | Piv5-based coronavirus vaccines and methods of use thereof |
-
2021
- 2021-09-21 BR BR112023005043A patent/BR112023005043A2/pt unknown
- 2021-09-21 EP EP21870396.5A patent/EP4213872A4/en active Pending
- 2021-09-21 WO PCT/US2021/051196 patent/WO2022061264A1/en active Application Filing
- 2021-09-21 CA CA3196157A patent/CA3196157A1/en active Pending
- 2021-09-21 AU AU2021342576A patent/AU2021342576A1/en active Pending
- 2021-09-21 MX MX2023003199A patent/MX2023003199A/es unknown
- 2021-09-21 JP JP2023518132A patent/JP2023542922A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
MX2023003199A (es) | 2023-04-13 |
JP2023542922A (ja) | 2023-10-12 |
EP4213872A4 (en) | 2024-03-27 |
AU2021342576A1 (en) | 2023-04-06 |
EP4213872A1 (en) | 2023-07-26 |
WO2022061264A1 (en) | 2022-03-24 |
CA3196157A1 (en) | 2022-03-24 |
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