BR112022012594A2 - Dosagem de gama-hidroxibutirato (ghb) - Google Patents
Dosagem de gama-hidroxibutirato (ghb)Info
- Publication number
- BR112022012594A2 BR112022012594A2 BR112022012594A BR112022012594A BR112022012594A2 BR 112022012594 A2 BR112022012594 A2 BR 112022012594A2 BR 112022012594 A BR112022012594 A BR 112022012594A BR 112022012594 A BR112022012594 A BR 112022012594A BR 112022012594 A2 BR112022012594 A2 BR 112022012594A2
- Authority
- BR
- Brazil
- Prior art keywords
- ghb
- hydroxybutyrate
- gamma
- dosage
- narcolepsy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Abstract
A presente invenção refere-se a métodos de administração de formulações de GHB para o tratamento de narcolepsia e outras condições.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962953288P | 2019-12-24 | 2019-12-24 | |
US202062993372P | 2020-03-23 | 2020-03-23 | |
US202063000547P | 2020-03-27 | 2020-03-27 | |
US202063052676P | 2020-07-16 | 2020-07-16 | |
PCT/US2020/066561 WO2021133778A1 (en) | 2019-12-24 | 2020-12-22 | Gamma-hydroxybutyrate (ghb) dosing |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112022012594A2 true BR112022012594A2 (pt) | 2022-09-06 |
Family
ID=74191949
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112022012594A BR112022012594A2 (pt) | 2019-12-24 | 2020-12-22 | Dosagem de gama-hidroxibutirato (ghb) |
Country Status (14)
Country | Link |
---|---|
US (2) | US20210186907A1 (pt) |
EP (1) | EP4081204A1 (pt) |
JP (1) | JP2023508975A (pt) |
KR (1) | KR20220119429A (pt) |
CN (1) | CN115209885A (pt) |
AU (1) | AU2020414694A1 (pt) |
BR (1) | BR112022012594A2 (pt) |
CA (1) | CA3162974A1 (pt) |
CL (1) | CL2022001743A1 (pt) |
CO (1) | CO2022010330A2 (pt) |
IL (1) | IL294176A (pt) |
MX (1) | MX2022007968A (pt) |
TW (1) | TW202135790A (pt) |
WO (1) | WO2021133778A1 (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120076865A1 (en) | 2010-03-24 | 2012-03-29 | Jazz Pharmaceuticals, Inc. | Controlled release dosage forms for high dose, water soluble and hygroscopic drug substances |
US10398662B1 (en) | 2015-02-18 | 2019-09-03 | Jazz Pharma Ireland Limited | GHB formulation and method for its manufacture |
US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
UY37341A (es) | 2016-07-22 | 2017-11-30 | Flamel Ireland Ltd | Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada |
US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US20180263936A1 (en) | 2017-03-17 | 2018-09-20 | Jazz Pharmaceuticals Ireland Limited | Gamma-hydroxybutyrate compositions and their use for the treatment of disorders |
AU2019383389A1 (en) | 2018-11-19 | 2021-05-06 | Jazz Pharmaceuticals Ireland Limited | Alcohol-resistant drug formulations |
CA3127871A1 (en) | 2019-03-01 | 2020-09-10 | Flamel Ireland Limited | Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state |
US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69907508T2 (de) | 1998-12-23 | 2003-11-20 | Orphan Medical Inc | Mikrobenbeständige und stabilisierte lösungen, die gamma-hydroxybuttersäuresalze zur behandlung von narkolepsie enthalten |
EP1325014B1 (en) | 2000-09-22 | 2012-05-23 | JPI Commercial, LLC | Gamma-hydroxybutyrate compositions containing carbohydrate carriers |
US7610153B2 (en) * | 2002-02-13 | 2009-10-27 | Virginia Commonwealth University | Multi-drug titration and evaluation |
US7668730B2 (en) | 2002-12-17 | 2010-02-23 | JPI Commercial, LLC. | Sensitive drug distribution system and method |
US8778398B2 (en) | 2008-11-04 | 2014-07-15 | Jazz Pharmaceuticals, Inc. | Immediate release formulations and dosage forms of gamma-hydroxybutyrate |
US8771735B2 (en) | 2008-11-04 | 2014-07-08 | Jazz Pharmaceuticals, Inc. | Immediate release dosage forms of sodium oxybate |
US8591922B1 (en) | 2012-12-14 | 2013-11-26 | Jazz Pharmacuticals, Inc. | Gamma-hydroxybutyrate compositions and their use for the treatment of disorders |
US9050302B2 (en) | 2013-03-01 | 2015-06-09 | Jazz Pharmaceuticals Ireland Limited | Method of administration of gamma hydroxybutyrate with monocarboxylate transporters |
US9801852B2 (en) | 2013-08-30 | 2017-10-31 | Jazz Pharmaceuticals, Inc. | Devices and methods for facilitating and controlling use of a medication |
US20180263936A1 (en) * | 2017-03-17 | 2018-09-20 | Jazz Pharmaceuticals Ireland Limited | Gamma-hydroxybutyrate compositions and their use for the treatment of disorders |
-
2020
- 2020-12-22 KR KR1020227024876A patent/KR20220119429A/ko unknown
- 2020-12-22 TW TW109145587A patent/TW202135790A/zh unknown
- 2020-12-22 US US17/130,769 patent/US20210186907A1/en not_active Abandoned
- 2020-12-22 BR BR112022012594A patent/BR112022012594A2/pt unknown
- 2020-12-22 MX MX2022007968A patent/MX2022007968A/es unknown
- 2020-12-22 CA CA3162974A patent/CA3162974A1/en active Pending
- 2020-12-22 EP EP20842864.9A patent/EP4081204A1/en active Pending
- 2020-12-22 JP JP2022539046A patent/JP2023508975A/ja active Pending
- 2020-12-22 IL IL294176A patent/IL294176A/en unknown
- 2020-12-22 AU AU2020414694A patent/AU2020414694A1/en active Pending
- 2020-12-22 CN CN202080097472.7A patent/CN115209885A/zh active Pending
- 2020-12-22 WO PCT/US2020/066561 patent/WO2021133778A1/en active Application Filing
-
2021
- 2021-08-06 US US17/396,104 patent/US20210361601A1/en active Pending
-
2022
- 2022-06-24 CL CL2022001743A patent/CL2022001743A1/es unknown
- 2022-07-22 CO CONC2022/0010330A patent/CO2022010330A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
EP4081204A1 (en) | 2022-11-02 |
CN115209885A (zh) | 2022-10-18 |
MX2022007968A (es) | 2022-09-02 |
US20210361601A1 (en) | 2021-11-25 |
US20210186907A1 (en) | 2021-06-24 |
TW202135790A (zh) | 2021-10-01 |
IL294176A (en) | 2022-08-01 |
WO2021133778A1 (en) | 2021-07-01 |
AU2020414694A1 (en) | 2022-08-18 |
KR20220119429A (ko) | 2022-08-29 |
CO2022010330A2 (es) | 2022-10-21 |
CA3162974A1 (en) | 2021-07-01 |
JP2023508975A (ja) | 2023-03-06 |
CL2022001743A1 (es) | 2023-02-10 |
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