BR112019008384A2 - composição farmacêutica, processos para tratamento e seus usos - Google Patents
composição farmacêutica, processos para tratamento e seus usosInfo
- Publication number
- BR112019008384A2 BR112019008384A2 BR112019008384A BR112019008384A BR112019008384A2 BR 112019008384 A2 BR112019008384 A2 BR 112019008384A2 BR 112019008384 A BR112019008384 A BR 112019008384A BR 112019008384 A BR112019008384 A BR 112019008384A BR 112019008384 A2 BR112019008384 A2 BR 112019008384A2
- Authority
- BR
- Brazil
- Prior art keywords
- processes
- treatment
- pharmaceutical composition
- chronic kidney
- kidney disease
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 208000020832 chronic kidney disease Diseases 0.000 abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- OBWASQILIWPZMG-QZMOQZSNSA-N empagliflozin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1C1=CC=C(Cl)C(CC=2C=CC(O[C@@H]3COCC3)=CC=2)=C1 OBWASQILIWPZMG-QZMOQZSNSA-N 0.000 abstract 1
- 229960003345 empagliflozin Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
Abstract
a presente invenção refere-se a processos para tratamento ou prevenção de doença crônica de rim e doença cardiovascular em pacientes com doença crônica de rim compreendendo administração de empagliflozina para o paciente.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662420062P | 2016-11-10 | 2016-11-10 | |
US201762514249P | 2017-06-02 | 2017-06-02 | |
PCT/EP2017/078577 WO2018087132A1 (en) | 2016-11-10 | 2017-11-08 | Pharmaceutical composition, methods for treating and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112019008384A2 true BR112019008384A2 (pt) | 2019-07-09 |
Family
ID=60293959
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112019008384A BR112019008384A2 (pt) | 2016-11-10 | 2017-11-08 | composição farmacêutica, processos para tratamento e seus usos |
Country Status (13)
Country | Link |
---|---|
US (4) | US20180125813A1 (pt) |
EP (1) | EP3538107A1 (pt) |
JP (2) | JP2019533709A (pt) |
KR (2) | KR20190084096A (pt) |
CN (1) | CN109922813A (pt) |
AU (2) | AU2017357589B2 (pt) |
BR (1) | BR112019008384A2 (pt) |
CA (1) | CA3039745A1 (pt) |
CL (1) | CL2019001214A1 (pt) |
MA (1) | MA46742A (pt) |
MX (2) | MX2019005435A (pt) |
PH (1) | PH12019501018A1 (pt) |
WO (1) | WO2018087132A1 (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7772191B2 (en) | 2005-05-10 | 2010-08-10 | Boehringer Ingelheim International Gmbh | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein |
US10610489B2 (en) | 2009-10-02 | 2020-04-07 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, pharmaceutical dosage form, process for their preparation, methods for treating and uses thereof |
UY33937A (es) | 2011-03-07 | 2012-09-28 | Boehringer Ingelheim Int | Composiciones farmacéuticas que contienen inhibidores de dpp-4 y/o sglt-2 y metformina |
US11813275B2 (en) | 2013-04-05 | 2023-11-14 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
HUE041709T2 (hu) | 2013-04-05 | 2019-05-28 | Boehringer Ingelheim Int | Az empagliflozin terápiás alkalmazásai |
US20140303097A1 (en) | 2013-04-05 | 2014-10-09 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
CN113181161A (zh) | 2013-04-18 | 2021-07-30 | 勃林格殷格翰国际有限公司 | 药物组合物、治疗方法及其用途 |
CN112557533A (zh) * | 2020-11-29 | 2021-03-26 | 北京康立生医药技术开发有限公司 | 一种恩格列净的分析方法 |
WO2023114170A1 (en) * | 2021-12-14 | 2023-06-22 | Boehringer Ingelheim International Gmbh | Aldosterone synthase inhibitors for treating chronic kidney disease |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RS52365B (en) | 2004-03-16 | 2012-12-31 | Boehringer Ingelheim International Gmbh | BENZOL DERIVATIVES SUBSTITUTED BY GLUCOPYRANOSIL, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS, THEIR USE AND THE PROCEDURE FOR THEIR PRODUCTION |
UA91546C2 (uk) | 2005-05-03 | 2010-08-10 | Бьорінгер Інгельхайм Інтернаціональ Гмбх | КРИСТАЛІЧНА ФОРМА 1-ХЛОР-4-(β-D-ГЛЮКОПІРАНОЗ-1-ИЛ)-2-[4-((S)-ТЕТРАГІДРОФУРАН-3-ІЛОКСИ)-БЕНЗИЛ]-БЕНЗОЛУ, СПОСІБ ЇЇ ОДЕРЖАННЯ ТА ЇЇ ЗАСТОСУВАННЯ ПРИ ПРИГОТУВАННІ ЛІКАРСЬКИХ ЗАСОБІВ |
US7772191B2 (en) | 2005-05-10 | 2010-08-10 | Boehringer Ingelheim International Gmbh | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein |
AR056195A1 (es) | 2005-09-15 | 2007-09-26 | Boehringer Ingelheim Int | Procedimientos para preparar derivados de (etinil-bencil)-benceno sustituidos de glucopiranosilo y compuestos intermedios de los mismos |
UY32427A (es) | 2009-02-13 | 2010-09-30 | Boheringer Ingelheim Internat Gmbh | Composicion farmaceutica, forma farmaceutica, procedimiento para su preparacion, metodos de tratamiento y usos de la misma |
PT2395968T (pt) | 2009-02-13 | 2024-03-05 | Boehringer Ingelheim Int | Composição farmacêutica compreendendo derivados de glucopiranosil difenilmetano, sua forma de dosagem farmacêutica, processo para a sua preparação e suas utilizações para controlo glicémico melhorado num doente |
JP5758900B2 (ja) | 2009-09-30 | 2015-08-05 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | グルコピラノシル置換ベンジルベンゼン誘導体の調製方法 |
NZ598318A (en) | 2009-09-30 | 2014-02-28 | Boehringer Ingelheim Int | Method for the preparation of a crystalline form of 1-chloro-4- (beta-d-glucopyranos-1-yl)-2-(4-((s)-tetrahydrofuran-3-yloxy)benzyl)benzene |
US10610489B2 (en) | 2009-10-02 | 2020-04-07 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, pharmaceutical dosage form, process for their preparation, methods for treating and uses thereof |
UY33937A (es) | 2011-03-07 | 2012-09-28 | Boehringer Ingelheim Int | Composiciones farmacéuticas que contienen inhibidores de dpp-4 y/o sglt-2 y metformina |
US20130035298A1 (en) * | 2011-07-08 | 2013-02-07 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
US9555001B2 (en) | 2012-03-07 | 2017-01-31 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition and uses thereof |
CA2812519A1 (en) * | 2013-04-05 | 2014-10-05 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
HUE041709T2 (hu) * | 2013-04-05 | 2019-05-28 | Boehringer Ingelheim Int | Az empagliflozin terápiás alkalmazásai |
CN113181161A (zh) * | 2013-04-18 | 2021-07-30 | 勃林格殷格翰国际有限公司 | 药物组合物、治疗方法及其用途 |
-
2017
- 2017-11-08 CN CN201780069320.4A patent/CN109922813A/zh active Pending
- 2017-11-08 MX MX2019005435A patent/MX2019005435A/es unknown
- 2017-11-08 KR KR1020197016631A patent/KR20190084096A/ko not_active IP Right Cessation
- 2017-11-08 BR BR112019008384A patent/BR112019008384A2/pt unknown
- 2017-11-08 CA CA3039745A patent/CA3039745A1/en active Pending
- 2017-11-08 US US15/806,389 patent/US20180125813A1/en not_active Abandoned
- 2017-11-08 EP EP17797137.1A patent/EP3538107A1/en active Pending
- 2017-11-08 AU AU2017357589A patent/AU2017357589B2/en active Active
- 2017-11-08 WO PCT/EP2017/078577 patent/WO2018087132A1/en active Application Filing
- 2017-11-08 JP JP2019524277A patent/JP2019533709A/ja active Pending
- 2017-11-08 MA MA046742A patent/MA46742A/fr unknown
- 2017-11-08 KR KR1020237038843A patent/KR20230162125A/ko not_active Application Discontinuation
-
2019
- 2019-05-02 CL CL2019001214A patent/CL2019001214A1/es unknown
- 2019-05-08 PH PH12019501018A patent/PH12019501018A1/en unknown
- 2019-05-09 MX MX2023000796A patent/MX2023000796A/es unknown
-
2020
- 2020-01-09 US US16/738,116 patent/US20200138770A1/en not_active Abandoned
- 2020-11-10 US US17/094,045 patent/US20210228533A1/en not_active Abandoned
-
2022
- 2022-06-03 US US17/831,460 patent/US20220288012A1/en active Pending
- 2022-10-24 JP JP2022170030A patent/JP2023010710A/ja active Pending
-
2023
- 2023-05-27 AU AU2023203321A patent/AU2023203321A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CL2019001214A1 (es) | 2019-07-26 |
CA3039745A1 (en) | 2018-05-17 |
AU2017357589A1 (en) | 2019-04-18 |
AU2017357589B2 (en) | 2023-05-11 |
CN109922813A (zh) | 2019-06-21 |
KR20190084096A (ko) | 2019-07-15 |
US20210228533A1 (en) | 2021-07-29 |
US20180125813A1 (en) | 2018-05-10 |
US20220288012A1 (en) | 2022-09-15 |
PH12019501018A1 (en) | 2019-12-16 |
JP2019533709A (ja) | 2019-11-21 |
MX2023000796A (es) | 2023-02-27 |
WO2018087132A1 (en) | 2018-05-17 |
MX2019005435A (es) | 2019-07-10 |
EP3538107A1 (en) | 2019-09-18 |
AU2023203321A1 (en) | 2023-06-22 |
JP2023010710A (ja) | 2023-01-20 |
US20200138770A1 (en) | 2020-05-07 |
KR20230162125A (ko) | 2023-11-28 |
MA46742A (fr) | 2019-09-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] |