BR112019005748A2 - affinity-conjugates of oligonucleotides and uses of these - Google Patents

affinity-conjugates of oligonucleotides and uses of these

Info

Publication number
BR112019005748A2
BR112019005748A2 BR112019005748A BR112019005748A BR112019005748A2 BR 112019005748 A2 BR112019005748 A2 BR 112019005748A2 BR 112019005748 A BR112019005748 A BR 112019005748A BR 112019005748 A BR112019005748 A BR 112019005748A BR 112019005748 A2 BR112019005748 A2 BR 112019005748A2
Authority
BR
Brazil
Prior art keywords
conjugates
affinity
oligonucleotides
compositions
methods
Prior art date
Application number
BR112019005748A
Other languages
Portuguese (pt)
Inventor
J Belmont Brian
Vigneault Francois
J Goldfless Stephen
Adrian Briggs Wrangham
Original Assignee
Abvitro Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2016/053598 external-priority patent/WO2017053905A1/en
Application filed by Abvitro Llc filed Critical Abvitro Llc
Publication of BR112019005748A2 publication Critical patent/BR112019005748A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

Abstract

são aqui proporcionados métodos e composições para caracterização de célula única usando afinidade-conjugados de oligonucleotídeo. são aqui proporcionados métodos e composições para caracterização de célula única usando tetrâmero-conjugados de oligonucleotídeo.Methods and compositions for single cell characterization using affinity-oligonucleotide conjugates are provided herein. Methods and compositions for single cell characterization using oligonucleotide tetramer-conjugates are provided herein.

BR112019005748A 2016-09-24 2017-01-12 affinity-conjugates of oligonucleotides and uses of these BR112019005748A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US2016/053598 WO2017053905A1 (en) 2015-09-24 2016-09-24 Affinity-oligonucleotide conjugates and uses thereof
PCT/US2017/013274 WO2018057051A1 (en) 2016-09-24 2017-01-12 Affinity-oligonucleotide conjugates and uses thereof

Publications (1)

Publication Number Publication Date
BR112019005748A2 true BR112019005748A2 (en) 2019-06-18

Family

ID=57960826

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019005748A BR112019005748A2 (en) 2016-09-24 2017-01-12 affinity-conjugates of oligonucleotides and uses of these

Country Status (5)

Country Link
JP (1) JP6929354B2 (en)
AU (1) AU2017332495A1 (en)
BR (1) BR112019005748A2 (en)
IL (1) IL265471A (en)
WO (1) WO2018057051A1 (en)

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EP3807636B1 (en) 2018-06-15 2024-01-31 F. Hoffmann-La Roche AG A system for identification of antigens recognized by t cell receptors expressed on tumor infiltrating lymphocytes
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AU2019405752A1 (en) * 2018-12-18 2021-08-12 Mbl International Corp. Compositions of streptavidin-oligo conjugates of pMHC occupancy
WO2020162452A1 (en) * 2019-02-04 2020-08-13 国立大学法人愛媛大学 Car library and production method for scfv
CA3181835A1 (en) * 2020-06-09 2021-12-16 Anders Stahlberg Lymphocyte clonality determination

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Also Published As

Publication number Publication date
JP2019537430A (en) 2019-12-26
JP6929354B2 (en) 2021-09-01
WO2018057051A1 (en) 2018-03-29
IL265471A (en) 2019-05-30
AU2017332495A1 (en) 2019-04-11

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