BR112018010023A2 - melhoramentos relativos aos substratos para a fixação de moléculas - Google Patents

melhoramentos relativos aos substratos para a fixação de moléculas

Info

Publication number
BR112018010023A2
BR112018010023A2 BR112018010023A BR112018010023A BR112018010023A2 BR 112018010023 A2 BR112018010023 A2 BR 112018010023A2 BR 112018010023 A BR112018010023 A BR 112018010023A BR 112018010023 A BR112018010023 A BR 112018010023A BR 112018010023 A2 BR112018010023 A2 BR 112018010023A2
Authority
BR
Brazil
Prior art keywords
substrate
enhancements
molecule fixation
fixation
molecule
Prior art date
Application number
BR112018010023A
Other languages
English (en)
Inventor
Richardson Ciaran
Upadhyay Deepesh
Benchikh Elouard
Mcconnell Ivan
Lamont John
Fitzgerald Peter
Original Assignee
Randox Laboratories Ltd
Randox Teoranta
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Randox Laboratories Ltd, Randox Teoranta filed Critical Randox Laboratories Ltd
Publication of BR112018010023A2 publication Critical patent/BR112018010023A2/pt

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093Microreactors, e.g. miniaturised or microfabricated reactors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00Layered products comprising a layer of synthetic resin
    • B32B27/06Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B3/00Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form
    • B32B3/10Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form characterised by a discontinuous layer, i.e. formed of separate pieces of material
    • B32B3/12Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form characterised by a discontinuous layer, i.e. formed of separate pieces of material characterised by a layer of regularly- arranged cells, e.g. a honeycomb structure
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09DCOATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D11/00Inks
    • C09D11/02Printing inks
    • C09D11/03Printing inks characterised by features other than the chemical nature of the binder
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09DCOATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D11/00Inks
    • C09D11/02Printing inks
    • C09D11/10Printing inks based on artificial resins
    • C09D11/102Printing inks based on artificial resins containing macromolecular compounds obtained by reactions other than those only involving unsaturated carbon-to-carbon bonds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00608DNA chips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00632Introduction of reactive groups to the surface
    • B01J2219/00637Introduction of reactive groups to the surface by coating it with another layer
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781Aspects relating to microreactors
    • B01J2219/00851Additional features
    • B01J2219/00855Surface features

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Materials Engineering (AREA)
  • Sustainable Development (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Paints Or Removers (AREA)
  • Adhesives Or Adhesive Processes (AREA)

Abstract

a presente invenção refere-se a um substrato compreendendo um revestimento de um material de mascaramento, e uma pluralidade de zonas de reação distintas em que um ou mais agentes de ligação são destinados a serem ligados, onde essas zonas são áreas sem revestimento sobre o substrato.
BR112018010023A 2015-11-18 2016-11-18 melhoramentos relativos aos substratos para a fixação de moléculas BR112018010023A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1520341.7A GB201520341D0 (en) 2015-11-18 2015-11-18 Improvements relating to substrates for the attachment of molecules
PCT/GB2016/053608 WO2017085509A1 (en) 2015-11-18 2016-11-18 Improvements relating to substrates for the attachment of molecules

Publications (1)

Publication Number Publication Date
BR112018010023A2 true BR112018010023A2 (pt) 2018-11-21

Family

ID=55132977

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018010023A BR112018010023A2 (pt) 2015-11-18 2016-11-18 melhoramentos relativos aos substratos para a fixação de moléculas

Country Status (12)

Country Link
US (3) US10279332B2 (pt)
EP (1) EP3377900B1 (pt)
JP (1) JP6943448B2 (pt)
KR (1) KR102613057B1 (pt)
CN (1) CN108700578B (pt)
AU (1) AU2016355117B2 (pt)
BR (1) BR112018010023A2 (pt)
CA (1) CA3005515C (pt)
GB (1) GB201520341D0 (pt)
HK (1) HK1254090A1 (pt)
RU (1) RU2742666C2 (pt)
WO (1) WO2017085509A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201818744D0 (en) 2018-11-16 2019-01-02 Randox Laboratories Ltd Detection of bladder cancer
EP4314822A1 (en) 2021-03-31 2024-02-07 Randox Laboratories Ltd. Detection assay
WO2022207863A1 (en) 2021-03-31 2022-10-06 Randox Laboratories Ltd Coronavirus assay
GB202109635D0 (en) 2021-07-02 2021-08-18 Randox Laboratories Ltd Vision system
GB202114088D0 (en) 2021-10-01 2021-11-17 Randox Laboratories Detection of bladder cancer in males
WO2024092388A1 (zh) * 2022-10-31 2024-05-10 深圳华大智造科技股份有限公司 一种核酸加载试剂及用其检测测序芯片吸附能力的方法

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CZ297165B6 (cs) * 1997-04-21 2006-09-13 Randox Laboratories Ltd. A British Company Of Ardmore Zpusob výroby zarízení s pevnou fází k provádení multianalytních rozboru
EP0874242B2 (en) * 1997-04-21 2009-06-03 Randox Laboratories Ltd. Device and apparatus for the simultaneous detection of multiple analytes
JP3610231B2 (ja) * 1997-08-01 2005-01-12 キヤノン株式会社 反応場アレー、反応場アレーの製造方法、反応場アレーを用いた反応方法及び反応場アレーを用いた試料溶液中の物質の定量方法
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Also Published As

Publication number Publication date
CN108700578B (zh) 2021-09-24
GB201520341D0 (en) 2015-12-30
JP6943448B2 (ja) 2021-09-29
US10279332B2 (en) 2019-05-07
RU2018118166A3 (pt) 2020-03-18
EP3377900B1 (en) 2021-09-15
AU2016355117B2 (en) 2023-05-25
KR102613057B1 (ko) 2023-12-11
JP2018534577A (ja) 2018-11-22
CN108700578A (zh) 2018-10-23
US20180339282A1 (en) 2018-11-29
US11396003B2 (en) 2022-07-26
AU2016355117A1 (en) 2018-06-07
US20190247820A1 (en) 2019-08-15
CA3005515C (en) 2023-07-04
RU2742666C2 (ru) 2021-02-09
KR20180115257A (ko) 2018-10-22
RU2018118166A (ru) 2019-12-18
US20190344240A1 (en) 2019-11-14
WO2017085509A1 (en) 2017-05-26
EP3377900A1 (en) 2018-09-26
HK1254090A1 (zh) 2019-07-12
CA3005515A1 (en) 2017-05-26
US11383216B2 (en) 2022-07-12

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