BR112018010023A2 - melhoramentos relativos aos substratos para a fixação de moléculas - Google Patents
melhoramentos relativos aos substratos para a fixação de moléculasInfo
- Publication number
- BR112018010023A2 BR112018010023A2 BR112018010023A BR112018010023A BR112018010023A2 BR 112018010023 A2 BR112018010023 A2 BR 112018010023A2 BR 112018010023 A BR112018010023 A BR 112018010023A BR 112018010023 A BR112018010023 A BR 112018010023A BR 112018010023 A2 BR112018010023 A2 BR 112018010023A2
- Authority
- BR
- Brazil
- Prior art keywords
- substrate
- enhancements
- molecule fixation
- fixation
- molecule
- Prior art date
Links
- 239000000758 substrate Substances 0.000 title abstract 3
- 239000011230 binding agent Substances 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 230000000873 masking effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B3/00—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form
- B32B3/10—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form characterised by a discontinuous layer, i.e. formed of separate pieces of material
- B32B3/12—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shape; Layered products comprising a layer having particular features of form characterised by a discontinuous layer, i.e. formed of separate pieces of material characterised by a layer of regularly- arranged cells, e.g. a honeycomb structure
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D11/00—Inks
- C09D11/02—Printing inks
- C09D11/03—Printing inks characterised by features other than the chemical nature of the binder
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D11/00—Inks
- C09D11/02—Printing inks
- C09D11/10—Printing inks based on artificial resins
- C09D11/102—Printing inks based on artificial resins containing macromolecular compounds obtained by reactions other than those only involving unsaturated carbon-to-carbon bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00608—DNA chips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00632—Introduction of reactive groups to the surface
- B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00851—Additional features
- B01J2219/00855—Surface features
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Materials Engineering (AREA)
- Sustainable Development (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Application Of Or Painting With Fluid Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Paints Or Removers (AREA)
- Adhesives Or Adhesive Processes (AREA)
Abstract
a presente invenção refere-se a um substrato compreendendo um revestimento de um material de mascaramento, e uma pluralidade de zonas de reação distintas em que um ou mais agentes de ligação são destinados a serem ligados, onde essas zonas são áreas sem revestimento sobre o substrato.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1520341.7A GB201520341D0 (en) | 2015-11-18 | 2015-11-18 | Improvements relating to substrates for the attachment of molecules |
PCT/GB2016/053608 WO2017085509A1 (en) | 2015-11-18 | 2016-11-18 | Improvements relating to substrates for the attachment of molecules |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112018010023A2 true BR112018010023A2 (pt) | 2018-11-21 |
Family
ID=55132977
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018010023A BR112018010023A2 (pt) | 2015-11-18 | 2016-11-18 | melhoramentos relativos aos substratos para a fixação de moléculas |
Country Status (12)
Country | Link |
---|---|
US (3) | US10279332B2 (pt) |
EP (1) | EP3377900B1 (pt) |
JP (1) | JP6943448B2 (pt) |
KR (1) | KR102613057B1 (pt) |
CN (1) | CN108700578B (pt) |
AU (1) | AU2016355117B2 (pt) |
BR (1) | BR112018010023A2 (pt) |
CA (1) | CA3005515C (pt) |
GB (1) | GB201520341D0 (pt) |
HK (1) | HK1254090A1 (pt) |
RU (1) | RU2742666C2 (pt) |
WO (1) | WO2017085509A1 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201818744D0 (en) | 2018-11-16 | 2019-01-02 | Randox Laboratories Ltd | Detection of bladder cancer |
EP4314822A1 (en) | 2021-03-31 | 2024-02-07 | Randox Laboratories Ltd. | Detection assay |
WO2022207863A1 (en) | 2021-03-31 | 2022-10-06 | Randox Laboratories Ltd | Coronavirus assay |
GB202109635D0 (en) | 2021-07-02 | 2021-08-18 | Randox Laboratories Ltd | Vision system |
GB202114088D0 (en) | 2021-10-01 | 2021-11-17 | Randox Laboratories | Detection of bladder cancer in males |
WO2024092388A1 (zh) * | 2022-10-31 | 2024-05-10 | 深圳华大智造科技股份有限公司 | 一种核酸加载试剂及用其检测测序芯片吸附能力的方法 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ297165B6 (cs) * | 1997-04-21 | 2006-09-13 | Randox Laboratories Ltd. A British Company Of Ardmore | Zpusob výroby zarízení s pevnou fází k provádení multianalytních rozboru |
EP0874242B2 (en) * | 1997-04-21 | 2009-06-03 | Randox Laboratories Ltd. | Device and apparatus for the simultaneous detection of multiple analytes |
JP3610231B2 (ja) * | 1997-08-01 | 2005-01-12 | キヤノン株式会社 | 反応場アレー、反応場アレーの製造方法、反応場アレーを用いた反応方法及び反応場アレーを用いた試料溶液中の物質の定量方法 |
DE69841171D1 (de) * | 1997-08-01 | 2009-11-05 | Canon Kk | Reaktionsstellenarray, Verfahren zu seiner Herstellung, Reaktionsverfahren unter seiner Verwendung und quantitatives Bestimmungsverfahren für eine Substanz in einer Probelösung unter seiner Verwendung |
DE19756465C1 (de) * | 1997-12-18 | 1999-09-23 | Degussa | Modifizierte Ruße enthaltende Lacke und Druckfarben |
US6750023B2 (en) * | 1999-09-02 | 2004-06-15 | Corning Incorporated | Porous inorganic substrate for high-density arrays |
US20030219816A1 (en) * | 2001-07-02 | 2003-11-27 | Keith Solomon | Composite microarray slides |
US7678539B2 (en) * | 2000-08-10 | 2010-03-16 | Corning Incorporated | Arrays of biological membranes and methods and use thereof |
JP4378042B2 (ja) * | 2000-08-31 | 2009-12-02 | キヤノン株式会社 | 検体試料中の対象成分の検出方法、およびそれに用いる検出用基板 |
JP2003014760A (ja) * | 2001-04-27 | 2003-01-15 | Canon Inc | プローブ担体、プローブ固定用担体およびそれらの製造方法 |
WO2003046508A2 (en) * | 2001-11-09 | 2003-06-05 | Biomicroarrays, Inc. | High surface area substrates for microarrays and methods to make same |
KR100994566B1 (ko) * | 2003-01-20 | 2010-11-15 | 삼성전자주식회사 | 고정화 영역을 갖는 포토레지스트 막을 포함하는 어레이장치 및 이를 이용한 표적 물질 검출방법 |
US7282241B2 (en) * | 2003-04-22 | 2007-10-16 | International Business Machines Corporation | Patterned, high surface area substrate with hydrophilic/hydrophobic contrast, and method of use |
JP4606926B2 (ja) * | 2004-04-16 | 2011-01-05 | パナソニック株式会社 | 試料検査装置及びその製造方法 |
US20060040377A1 (en) * | 2004-08-17 | 2006-02-23 | Biocept, Inc. | Protein microarrays |
JP2007285968A (ja) * | 2006-04-19 | 2007-11-01 | Rohm Co Ltd | マイクロ流体チップ |
JP2012013550A (ja) * | 2010-06-30 | 2012-01-19 | Tosoh Corp | 粒子固定用構造体、粒子解析装置、及び解析方法 |
US20120035081A1 (en) * | 2010-08-05 | 2012-02-09 | Xerox Corporation | Non-polar solid inks for biomedical applications |
CA2856163C (en) * | 2011-10-28 | 2019-05-07 | Illumina, Inc. | Microarray fabrication system and method |
US10941396B2 (en) * | 2012-02-27 | 2021-03-09 | Becton, Dickinson And Company | Compositions and kits for molecular counting |
CN102879556A (zh) * | 2012-09-25 | 2013-01-16 | 中国电子科技集团公司第四十九研究所 | 一种定容量的生物芯片及其制备方法 |
CN103233274B (zh) * | 2013-05-06 | 2014-12-31 | 北京化工大学 | 一种聚合物基三维生物芯片的制备方法 |
CN103589631B (zh) * | 2013-11-19 | 2015-04-22 | 苏州晶方半导体科技股份有限公司 | 生物芯片封装结构及其封装方法 |
-
2015
- 2015-11-18 GB GBGB1520341.7A patent/GB201520341D0/en not_active Ceased
-
2016
- 2016-11-18 BR BR112018010023A patent/BR112018010023A2/pt unknown
- 2016-11-18 WO PCT/GB2016/053608 patent/WO2017085509A1/en active Application Filing
- 2016-11-18 CN CN201680070014.8A patent/CN108700578B/zh active Active
- 2016-11-18 CA CA3005515A patent/CA3005515C/en active Active
- 2016-11-18 EP EP16810446.1A patent/EP3377900B1/en active Active
- 2016-11-18 KR KR1020187017217A patent/KR102613057B1/ko active IP Right Grant
- 2016-11-18 JP JP2018526192A patent/JP6943448B2/ja active Active
- 2016-11-18 RU RU2018118166A patent/RU2742666C2/ru active
- 2016-11-18 AU AU2016355117A patent/AU2016355117B2/en active Active
-
2018
- 2018-05-18 US US15/983,484 patent/US10279332B2/en active Active
- 2018-10-15 HK HK18113154.5A patent/HK1254090A1/zh unknown
-
2019
- 2019-04-18 US US16/388,527 patent/US11396003B2/en active Active
- 2019-05-28 US US16/424,330 patent/US11383216B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CN108700578B (zh) | 2021-09-24 |
GB201520341D0 (en) | 2015-12-30 |
JP6943448B2 (ja) | 2021-09-29 |
US10279332B2 (en) | 2019-05-07 |
RU2018118166A3 (pt) | 2020-03-18 |
EP3377900B1 (en) | 2021-09-15 |
AU2016355117B2 (en) | 2023-05-25 |
KR102613057B1 (ko) | 2023-12-11 |
JP2018534577A (ja) | 2018-11-22 |
CN108700578A (zh) | 2018-10-23 |
US20180339282A1 (en) | 2018-11-29 |
US11396003B2 (en) | 2022-07-26 |
AU2016355117A1 (en) | 2018-06-07 |
US20190247820A1 (en) | 2019-08-15 |
CA3005515C (en) | 2023-07-04 |
RU2742666C2 (ru) | 2021-02-09 |
KR20180115257A (ko) | 2018-10-22 |
RU2018118166A (ru) | 2019-12-18 |
US20190344240A1 (en) | 2019-11-14 |
WO2017085509A1 (en) | 2017-05-26 |
EP3377900A1 (en) | 2018-09-26 |
HK1254090A1 (zh) | 2019-07-12 |
CA3005515A1 (en) | 2017-05-26 |
US11383216B2 (en) | 2022-07-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR112018010023A2 (pt) | melhoramentos relativos aos substratos para a fixação de moléculas | |
BR112018067962A2 (pt) | artigos absorventes | |
MA49858A (fr) | Composés, compositions et procédés | |
BR112017028318A2 (pt) | compostos antibacterianos | |
MX2018005292A (es) | Inhibidores de acc y usos de los mismos. | |
BR112018013065A2 (pt) | composições e métodos para o tratamento de hemoglobinopatias | |
BR112017028234A2 (pt) | composição antimicrobiana | |
BR112018012914A2 (pt) | composto, método para tratar, prevenir ou melhorar um ou mais sintomas de câncer, método para tratar, prevenir ou melhorar um ou mais sintomas de uma doença inflamatória e composição farmacêutica | |
MA50063A (fr) | Composés, compositions et procédés | |
BR112019005305A2 (pt) | compostos espirocíclicos | |
BR112018068341A2 (pt) | 6-hidróxi-4-oxo-1,4-di-hidropirimidina-5-carboxamidas como agonistas de apj | |
BR112015023207A8 (pt) | composições de ci-inh e métodos para prevenção e tratamento de desordens associadas à deficiência de inibidor de c1 esterase. | |
CL2018003267A1 (es) | Cápsulas que comprenden bencilpropargiléteres para usar como inhibidores de la nitrificación. | |
KR20180084732A (ko) | 비신뢰 컴퓨터들 상에서 프라이빗 프로그램을 실행하기 위한 시스템 및 프로세스 | |
BR112018012304A2 (pt) | composições e métodos para diminuir expressão de tau | |
EP3037489A4 (en) | Anti-corrosion coating composition, anti-corrosion coating film, and method for protecting base material from corrosion | |
BR112017018187A2 (pt) | composições compreendendo combinações de ácidos orgânicos | |
BR112017018172B8 (pt) | Método para romper um biofilme através de composições compreendendo combinações de ácidos orgânicos | |
BR112017028520A2 (pt) | Sistemas adesivo de laminação - poliéster- policarbonato-poliol | |
EP3388493A4 (en) | COATING COMPOSITION FOR FORMING A FRICTION RESISTANT COATING FILM, COATING FILM AND SUBSTRATE WITH COATING FILM | |
MA45553A (fr) | Substrats chimioluminescents | |
BR112017021691A2 (pt) | fita adesiva para prevenir a adesão de organismos aquaticos | |
PL3362525T3 (pl) | Kompozycja powłoki nawierzchniowej, sposób powlekania nawierzchni kompozycją powłoki nawierzchniowej oraz podłoże | |
EP3265523A4 (en) | Compositions containing hole carrier compounds and polymeric acids, and uses thereof | |
BR112017018113B8 (pt) | Composições compreendendo combinações de ácidos orgânicos |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] |