BR112018009951A8 - fármaco oftálmico - Google Patents
fármaco oftálmicoInfo
- Publication number
- BR112018009951A8 BR112018009951A8 BR112018009951A BR112018009951A BR112018009951A8 BR 112018009951 A8 BR112018009951 A8 BR 112018009951A8 BR 112018009951 A BR112018009951 A BR 112018009951A BR 112018009951 A BR112018009951 A BR 112018009951A BR 112018009951 A8 BR112018009951 A8 BR 112018009951A8
- Authority
- BR
- Brazil
- Prior art keywords
- coating
- ophthalmic drug
- layer
- syringe
- liquid formulation
- Prior art date
Links
- 239000003732 agents acting on the eye Substances 0.000 title abstract 3
- 229940023490 ophthalmic product Drugs 0.000 title abstract 3
- 239000011248 coating agent Substances 0.000 abstract 3
- 238000000576 coating method Methods 0.000 abstract 3
- 239000012669 liquid formulation Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 206010064930 age-related macular degeneration Diseases 0.000 abstract 1
- 230000004888 barrier function Effects 0.000 abstract 1
- 238000005461 lubrication Methods 0.000 abstract 1
- 208000002780 macular degeneration Diseases 0.000 abstract 1
- 229940071643 prefilled syringe Drugs 0.000 abstract 1
- 239000011253 protective coating Substances 0.000 abstract 1
- 229920001169 thermoplastic Polymers 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1468—Containers characterised by specific material properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/082—Inorganic materials
- A61L31/088—Other specific inorganic materials not covered by A61L31/084 or A61L31/086
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- A—HUMAN NECESSITIES
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- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
- A61M5/31505—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
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- A—HUMAN NECESSITIES
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3202—Devices for protection of the needle before use, e.g. caps
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- A—HUMAN NECESSITIES
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
- A61M5/5086—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile for indicating if defective, used, tampered with or unsterile
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C16/00—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes
- C23C16/04—Coating on selected surface areas, e.g. using masks
- C23C16/045—Coating cavities or hollow spaces, e.g. interior of tubes; Infiltration of porous substrates
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- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C16/00—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes
- C23C16/22—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the deposition of inorganic material, other than metallic material
- C23C16/30—Deposition of compounds, mixtures or solid solutions, e.g. borides, carbides, nitrides
- C23C16/40—Oxides
- C23C16/401—Oxides containing silicon
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- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C16/00—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes
- C23C16/44—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating
- C23C16/50—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating using electric discharges
- C23C16/505—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating using electric discharges using radio frequency discharges
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/10—Materials for lubricating medical devices
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
- A61L2420/08—Coatings comprising two or more layers
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
- A61M2005/3131—Syringe barrels specially adapted for improving sealing or sliding
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0222—Materials for reducing friction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Metallurgy (AREA)
- Mechanical Engineering (AREA)
- Materials Engineering (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Inorganic Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Surgery (AREA)
- Endocrinology (AREA)
- Physics & Mathematics (AREA)
- Plasma & Fusion (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
Abstract
fármaco oftálmico, kit, método para tratar qualquer uma ou mais dentre degeneração macular relacionada à idade, uso de uma formulação líquida, seringa pré-preenchida, e método para formar um tambor de seringa. trata-se de uma formulação líquida de um fármaco oftálmico em uma embalagem farmacêutica, por exemplo, uma seringa, cartucho ou frasco, produzido no todo ou em parte por um polímero termoplástico, revestido no interior com uma camada ou revestimento de fixação, uma camada ou revestimento de barreira, uma camada ou revestimento protetor de ph, e, opcionalmente, uma camada ou revestimento de lubrificação.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562257208P | 2015-11-18 | 2015-11-18 | |
PCT/US2016/062885 WO2017087871A1 (en) | 2015-11-18 | 2016-11-18 | Pharmaceutical package for ophthalmic formulations |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112018009951A2 BR112018009951A2 (pt) | 2018-11-06 |
BR112018009951A8 true BR112018009951A8 (pt) | 2019-02-26 |
Family
ID=57530836
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018009951A BR112018009951A8 (pt) | 2015-11-18 | 2016-11-18 | fármaco oftálmico |
Country Status (12)
Country | Link |
---|---|
US (2) | US11654046B2 (pt) |
EP (1) | EP3377040B8 (pt) |
JP (1) | JP7430485B2 (pt) |
KR (1) | KR20180105123A (pt) |
CN (1) | CN108883057A (pt) |
AU (1) | AU2016356717B2 (pt) |
BR (1) | BR112018009951A8 (pt) |
CA (1) | CA3005132A1 (pt) |
MX (1) | MX2018006139A (pt) |
RU (1) | RU2751510C2 (pt) |
WO (1) | WO2017087871A1 (pt) |
ZA (1) | ZA201803984B (pt) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3494950B1 (en) * | 2016-08-02 | 2023-09-27 | Feagle Co., Ltd | Acupuncture treatment device comprising plasma stimulation device |
ES2960921T3 (es) | 2017-03-27 | 2024-03-07 | Regeneron Pharma | Procedimiento de esterilización |
WO2018194918A1 (en) * | 2017-04-14 | 2018-10-25 | Sio2 Medical Products, Inc. | Coating systems on plastic substrates that inhibit free radical-induced degradation of biologics in primary packaging |
WO2018217995A1 (en) * | 2017-05-24 | 2018-11-29 | Formycon Ag | Sterilizable pre-filled pharmaceutical packages comprising a liquid formulation of a vegf-antagonist |
EP3630062A2 (en) * | 2017-05-24 | 2020-04-08 | SiO2 Medical Products, Inc. | Sterilizable pharmaceutical package for ophthalmic formulations |
CN111148695B (zh) | 2017-09-29 | 2022-03-04 | 豪夫迈·罗氏有限公司 | 预填充式注射器和制备预填充式注射器的方法 |
US20200297919A1 (en) * | 2017-09-29 | 2020-09-24 | F. Hoffmann-La Roche Ag | Prefilled syringe and method of preparing a prefilled syringe |
JP7408545B2 (ja) * | 2017-11-14 | 2024-01-05 | サノフイ | 注射デバイスのプランジャストッパ内への超音波センサの組み込み |
EP3761953A1 (en) | 2018-03-08 | 2021-01-13 | Coherus Biosciences, Inc. | Stable aqueous formulations of aflibercept |
US11426446B2 (en) | 2018-03-08 | 2022-08-30 | Coherus Biosciences, Inc. | Stable aqueous formulations of aflibercept |
CN112469457B (zh) * | 2018-07-31 | 2023-02-28 | 日本瑞翁株式会社 | 预充式注射器和预充式注射器的制造方法 |
JP7484715B2 (ja) * | 2018-07-31 | 2024-05-16 | 日本ゼオン株式会社 | プレフィルドシリンジおよびプレフィルドシリンジの製造方法 |
KR102574226B1 (ko) * | 2018-11-16 | 2023-09-04 | 코탁 재팬 엘엘씨 | 과산화수소 용액에 적합한 주사기 및 키트 |
JP2022523488A (ja) * | 2019-01-25 | 2022-04-25 | エスアイオーツー・メディカル・プロダクツ・インコーポレイテッド | バイオ医薬製品の製造、包装、配送及び評価で使用される共通接触面 |
PE20212185A1 (es) | 2019-02-18 | 2021-11-11 | Lilly Co Eli | Formulacion de anticuerpos terapeuticos |
CA3136275A1 (en) * | 2019-04-05 | 2020-10-08 | Sio2 Medical Products, Inc. | Biodegradable and compostable vessels, such as coffee pods, coated with pecvd coatings or layers |
JP6667859B1 (ja) * | 2019-05-31 | 2020-03-18 | 株式会社Kortuc | 放射線又は抗がん化学療法増感剤投与ホルダー |
US11911588B2 (en) * | 2019-08-06 | 2024-02-27 | Microvention, Inc. | Syringe |
WO2021050687A1 (en) | 2019-09-10 | 2021-03-18 | Coherus Biosciences, Inc. | Stable aqueous formulations of aflibercept |
JP2023505488A (ja) * | 2019-12-05 | 2023-02-09 | エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト | 注射器および気密性の試験方法 |
US20230047299A1 (en) * | 2020-01-28 | 2023-02-16 | Zeon Corporation | Pre-filled drug package and method of producing pre-filled drug package |
MX2022014531A (es) | 2020-05-21 | 2023-03-03 | Coherus Biosciences Inc | Sistemas y metodos para producir dispositivos de inyeccion esteriles. |
US20230303305A1 (en) * | 2020-07-28 | 2023-09-28 | Sio2 Medical Products, Inc. | Method and package for reducing the degradation of a drug and/or excipient, e.g. polysorbate stabilizer, in a pharmaceutical product |
WO2022028412A1 (zh) * | 2020-08-03 | 2022-02-10 | 江苏菲沃泰纳米科技股份有限公司 | 疏水疏油涂层及其制备方法和产品 |
US20240156724A1 (en) * | 2021-03-16 | 2024-05-16 | Vyluma Inc. | Multi-Dose Container for Ophthalmic Compositions |
TW202307255A (zh) * | 2021-05-17 | 2023-02-16 | 美商應用材料股份有限公司 | 包裝材料及製造方法 |
US20230080971A1 (en) * | 2021-09-08 | 2023-03-16 | Regeneron Pharmaceuticals, Inc. | Methods for delivering agents with pre-filled syringes to minimize intraocular inflammation |
EP4215230A1 (en) * | 2022-01-24 | 2023-07-26 | Becton Dickinson France | Gliding performances improved through trim rib dimensional geometry/shape |
WO2024051936A1 (en) * | 2022-09-07 | 2024-03-14 | Applied Materials, Inc. | Closure for pharmaceutical preparations and method and rotary deposition apparatus for manufacturing therefor |
Family Cites Families (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4294695A (en) | 1974-01-14 | 1981-10-13 | Standard Oil Company | Multi-phase separation methods and apparatus |
DE2629557B2 (de) | 1976-07-01 | 1980-05-14 | Paul E. Dr.Med. 8000 Muenchen Doerr | Einmai-Injektionsspritze |
US4424057A (en) | 1982-04-01 | 1984-01-03 | House Hugh A | Wet-dry syringe |
JPH034282Y2 (pt) | 1986-09-16 | 1991-02-04 | ||
US4820278A (en) | 1988-01-13 | 1989-04-11 | The Boeing Company | Non-contaminating renewable syringe |
EP0328699B1 (de) | 1988-02-16 | 1991-09-18 | Arzneimittel GmbH Apotheker Vetter & Co. Ravensburg | Spritze für medizinische Zwecke |
DE3916101A1 (de) | 1989-05-17 | 1990-11-22 | Vetter & Co Apotheker | Spritze fuer medizinische zwecke |
US4986820A (en) | 1989-06-23 | 1991-01-22 | Ultradent Products, Inc. | Syringe apparatus having improved plunger |
US5731144A (en) | 1990-06-11 | 1998-03-24 | Nexstar Pharmaceuticals, Inc. | High affinity TGFβ nucleic acid ligands |
US6124449A (en) | 1990-06-11 | 2000-09-26 | Nexstar Pharmaceuticals, Inc. | High affinity TGFβ nucleic acid ligands and inhibitors |
US5731424A (en) | 1990-06-11 | 1998-03-24 | Nexstar Pharmaceuticals, Inc. | High affinity TGFβ nucleic acid ligands and inhibitors |
US6582959B2 (en) | 1991-03-29 | 2003-06-24 | Genentech, Inc. | Antibodies to vascular endothelial cell growth factor |
AU732820B2 (en) | 1995-06-02 | 2001-05-03 | Nexstar Pharmaceuticals, Inc. | High-affinity oligonucleotide ligands to growth factors |
EP1238986B1 (en) | 1992-10-28 | 2008-06-25 | Genentech, Inc. | Use of Vascular endothelial cell growth factor antagonists |
DE4331137A1 (de) | 1993-05-06 | 1994-11-10 | Becton Dickinson Co | Spritze für medizinische Zwecke |
DE9321547U1 (de) | 1993-05-06 | 1999-07-15 | Becton Dickinson And Co., Franklin Lakes, N.J. | Spritze für medzinische Zwecke |
US5411489A (en) * | 1994-05-06 | 1995-05-02 | Sterling Winthrop Inc. | Pre-filled syringe and pre-filled cartridge having actuating cylinder/plunger rod combination for reducing syringing force |
DE4438360C2 (de) * | 1994-10-27 | 1999-05-20 | Schott Glas | Vorfüllbare partikelarme, sterile Einmalspritze für die Injektion von Präparaten und Verfahren zu ihrer Herstellung |
IL117645A (en) | 1995-03-30 | 2005-08-31 | Genentech Inc | Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration |
US5607400A (en) * | 1995-05-19 | 1997-03-04 | Becton, Dickinson And Company | Pre-fillable syringe and stopper assembly therefor |
US5607399A (en) | 1995-09-22 | 1997-03-04 | Becton, Dickinson And Company | Backstop device for a flangeless syringe |
US20020032315A1 (en) | 1997-08-06 | 2002-03-14 | Manuel Baca | Anti-vegf antibodies |
SI1787999T1 (sl) | 1997-04-07 | 2010-12-31 | Genentech Inc | Anti-VEGF protitelesa |
WO1998045331A2 (en) | 1997-04-07 | 1998-10-15 | Genentech, Inc. | Anti-vegf antibodies |
US6703020B1 (en) | 1999-04-28 | 2004-03-09 | Board Of Regents, The University Of Texas System | Antibody conjugate methods for selectively inhibiting VEGF |
ATE417928T1 (de) | 1999-06-08 | 2009-01-15 | Regeneron Pharma | Vegf-rezeptorchimären zur behandlung von augenkrankheiten, welche durch vaskuläre permeabilität charakterisiert sind. |
US6432089B1 (en) * | 2000-06-21 | 2002-08-13 | Medrad, Inc. | Medical syringe |
CN1301692C (zh) * | 2002-09-18 | 2007-02-28 | 阿勒根公司 | 眼植入物导入的器械 |
US20040167476A1 (en) * | 2003-02-24 | 2004-08-26 | Westbye Lars Tommy | Tamper evident needle guard for syringes |
US20050010175A1 (en) * | 2003-02-27 | 2005-01-13 | Beedon Daniel E. | Piston assembly for syringe |
JP4481587B2 (ja) * | 2003-04-25 | 2010-06-16 | テルモ株式会社 | シリンジ |
US7431989B2 (en) | 2003-05-06 | 2008-10-07 | Tribofilm Research, Inc. | Article with lubricated surface and method |
WO2005044853A2 (en) | 2003-11-01 | 2005-05-19 | Genentech, Inc. | Anti-vegf antibodies |
JP4430903B2 (ja) * | 2003-08-29 | 2010-03-10 | テルモ株式会社 | グリチルリチン酸水溶液充填プレフィルドシリンジ |
JP4708013B2 (ja) * | 2004-12-15 | 2011-06-22 | テルモ株式会社 | シリンジ |
HUE053612T2 (hu) | 2006-06-16 | 2021-07-28 | Regeneron Pharma | Intravitreális bevitelre alkalmas VEGF-antagonista készítmények |
DE102006048658B4 (de) | 2006-10-14 | 2014-03-27 | Khs Corpoplast Gmbh | PICVD-Beschichtung für Kunststoffbehälter und Verfahren zu deren Herstellung |
US20080228147A1 (en) * | 2007-03-15 | 2008-09-18 | Bristol-Myers Squibb Company | Injector for use with pre-filled syringes and method of assembly |
US8529521B2 (en) | 2007-04-23 | 2013-09-10 | Ultimed Inc. | Low-dosage syringe |
JP5711868B2 (ja) * | 2007-09-28 | 2015-05-07 | テルモ株式会社 | 安定なエダラボン含有水性製剤 |
US8721603B2 (en) * | 2008-01-15 | 2014-05-13 | West Pharmaceutical Services, Inc. | Syringe with co-molded hub and cannula |
AU2009210741A1 (en) | 2008-02-07 | 2009-08-13 | Amgen Inc. | Stabilized protein compositions |
KR102095257B1 (ko) | 2008-06-25 | 2020-04-01 | 노바르티스 아게 | Vegf를 억제하는 안정하고 가용성인 항체 |
ES2836948T3 (es) | 2008-11-03 | 2021-06-28 | Molecular Partners Ag | Proteínas de unión que inhiben la interacción del receptor de VEGF-A |
EP2251454B1 (en) * | 2009-05-13 | 2014-07-23 | SiO2 Medical Products, Inc. | Vessel coating and inspection |
US8322577B2 (en) | 2009-04-24 | 2012-12-04 | Agilent Technologies, Inc. | Syringe with improved plunger |
US7985188B2 (en) * | 2009-05-13 | 2011-07-26 | Cv Holdings Llc | Vessel, coating, inspection and processing apparatus |
DE102009023335A1 (de) | 2009-05-29 | 2010-12-02 | Lts Lohmann Therapie-Systeme Ag | Zweikammer Zylinder-Kolben-Einheit zur Lyophilisation, Lagerung, Rekonstitution und Applikation von Injektionslösungen für einen Injektor und Verfahren zum Befüllen der Zylinder-Kolben-Einheit |
US8530536B2 (en) | 2009-10-01 | 2013-09-10 | Momentive Performance Materials Inc. | Self-lubricating pharmaceutical syringe stoppers |
US8722178B2 (en) * | 2009-10-29 | 2014-05-13 | W. L. Gore & Associates, Inc. | Syringe stopper |
WO2011090717A1 (en) | 2009-12-28 | 2011-07-28 | Gvd Corporation | Coating methods, systems, and related articles |
WO2011117878A1 (en) | 2010-03-20 | 2011-09-29 | Pawan Trilokchand Agrawal | Plastic pre-filled syringe |
WO2011122574A1 (ja) | 2010-03-30 | 2011-10-06 | テルモ株式会社 | 摺動性被覆層保有医療用具およびシリンジ |
TWI510246B (zh) | 2010-04-30 | 2015-12-01 | Molecular Partners Ag | 抑制vegf-a受體交互作用的經修飾結合性蛋白質 |
JP5801586B2 (ja) * | 2011-03-31 | 2015-10-28 | テルモ株式会社 | 脂肪乳剤プレフィルドシリンジ製剤 |
EP2771301B1 (en) * | 2011-10-25 | 2017-12-20 | Corning Incorporated | Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients |
JP2013116289A (ja) | 2011-12-05 | 2013-06-13 | Daikyo Seiko Ltd | 医薬品用注射器 |
US9345846B1 (en) | 2012-05-15 | 2016-05-24 | Sio2 Medical Products, Inc. | Molding apparatus, method and syringe produced using same |
PL3679922T3 (pl) * | 2012-06-01 | 2022-01-03 | Novartis Ag | Strzykawka |
JOP20200175A1 (ar) * | 2012-07-03 | 2017-06-16 | Novartis Ag | حقنة |
AU2013100070B4 (en) | 2012-07-03 | 2013-04-04 | Novartis Ag | Use of device |
WO2014052792A1 (en) | 2012-09-28 | 2014-04-03 | Sio2 Medical Products, Inc. | Halogenated or parylene polymer coating |
CA2892294C (en) | 2012-11-30 | 2021-07-27 | Sio2 Medical Products, Inc. | Controlling the uniformity of pecvd deposition on medical syringes, cartridges, and the like |
EP4234753A3 (en) * | 2013-03-11 | 2023-11-01 | SiO2 Medical Products, Inc. | Coated packaging |
US9863042B2 (en) * | 2013-03-15 | 2018-01-09 | Sio2 Medical Products, Inc. | PECVD lubricity vessel coating, coating process and apparatus providing different power levels in two phases |
JP6673822B2 (ja) * | 2013-10-07 | 2020-03-25 | エスアイオーツー・メディカル・プロダクツ・インコーポレイテッド | 切り替え可能なプランジャー、フィルムコーテッドプランジャー及び関連のシリンジアセンブリ |
WO2015054075A1 (en) | 2013-10-07 | 2015-04-16 | Ocuject, Llc | Intraocular delivery devices and methods therefor |
WO2015071348A1 (en) | 2013-11-18 | 2015-05-21 | Formycon Ag | Pharmaceutical composition of an anti-vegf antibody |
JP6802069B2 (ja) | 2014-05-12 | 2020-12-16 | フォーマイコン アーゲーFormycon Ag | Vegf拮抗薬を収容したプレフィルドプラスチックシリンジ |
EP3377100A1 (en) * | 2015-11-18 | 2018-09-26 | Formycon AG | Pre-filled pharmaceutical package comprising a liquid formulation of a vegf-antagonist |
CN110168031B (zh) | 2016-12-27 | 2022-05-17 | 泰尔茂株式会社 | 涂层剂及利用该涂层剂进行表面处理而形成的医疗器械 |
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CN108883057A (zh) | 2018-11-23 |
RU2018120503A (ru) | 2019-12-19 |
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MX2018006139A (es) | 2019-03-14 |
AU2016356717A1 (en) | 2018-05-10 |
BR112018009951A2 (pt) | 2018-11-06 |
CA3005132A1 (en) | 2017-05-26 |
JP2018535974A (ja) | 2018-12-06 |
AU2016356717B2 (en) | 2022-09-29 |
EP3377040B8 (en) | 2024-06-05 |
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