BR112017026660A2 - composição e kit para tratamento de perda de fluidos que provocam hipotensão e/ou hipovolemia - Google Patents

composição e kit para tratamento de perda de fluidos que provocam hipotensão e/ou hipovolemia

Info

Publication number
BR112017026660A2
BR112017026660A2 BR112017026660A BR112017026660A BR112017026660A2 BR 112017026660 A2 BR112017026660 A2 BR 112017026660A2 BR 112017026660 A BR112017026660 A BR 112017026660A BR 112017026660 A BR112017026660 A BR 112017026660A BR 112017026660 A2 BR112017026660 A2 BR 112017026660A2
Authority
BR
Brazil
Prior art keywords
composition
fluid loss
hypovolemia
kit
impaired
Prior art date
Application number
BR112017026660A
Other languages
English (en)
Inventor
Feuerstein Giora
Michael Fitzpatrick Glen
Original Assignee
Cellphire Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellphire Inc filed Critical Cellphire Inc
Publication of BR112017026660A2 publication Critical patent/BR112017026660A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/77—Polymers containing oxygen of oxiranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

trata-se de uma composição que contém pelo menos um sal, pelo menos um sacarídeo natural ou sintético e pelo menos um polímero hidrofílico natural ou sintético não iônico de alto peso molecular. quando em uma forma líquida, a composição está pronta para infusão ou injeção nos pacientes que sofrem de perda de fluidos que causa volume e/ou pressão reduzidos na circulação sistêmica. a composição também é adequada para tratamento de afecções em órgão em que o fluxo sanguíneo é prejudicado ou insuficiente, o que resulta em danos ao órgão, incluindo perda de tecido. a invenção também se refere ao uso de uma profilaxia para prevenir consequências médicas de afecções antecipadas em que fluidos circulatórios depletados, baixa pressão sanguínea ou perfusão de órgão prejudicado exigem correção.
BR112017026660A 2015-06-10 2016-06-09 composição e kit para tratamento de perda de fluidos que provocam hipotensão e/ou hipovolemia BR112017026660A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562173900P 2015-06-10 2015-06-10
US201562261973P 2015-12-02 2015-12-02
PCT/US2016/036657 WO2016201081A1 (en) 2015-06-10 2016-06-09 Composition and methods for treatment of loss of fluids leading to hypotension and/or hypovolemia

Publications (1)

Publication Number Publication Date
BR112017026660A2 true BR112017026660A2 (pt) 2018-08-14

Family

ID=57504625

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017026660A BR112017026660A2 (pt) 2015-06-10 2016-06-09 composição e kit para tratamento de perda de fluidos que provocam hipotensão e/ou hipovolemia

Country Status (8)

Country Link
US (1) US20180169139A1 (pt)
EP (1) EP3307283B1 (pt)
JP (1) JP2018516965A (pt)
AU (1) AU2016276767B2 (pt)
BR (1) BR112017026660A2 (pt)
CA (1) CA2988610A1 (pt)
IL (1) IL256158A (pt)
WO (1) WO2016201081A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200093853A1 (en) * 2016-12-08 2020-03-26 Cellphire, Inc. Compositions and methods for treatment of loss of fluids leading to hypotension and/or hypovolemia
CN109009061B (zh) * 2018-06-20 2021-11-19 博动医学影像科技（上海）有限公司 基于血压修正获取血流特征值的计算方法及装置
CA3121200A1 (en) 2018-11-30 2020-06-04 Cellphire, Inc. Platelets as delivery agents
EP3886879A4 (en) 2018-11-30 2022-12-07 Cellphire Inc. PLATES AS DELIVERY AGENTS
CN114072159A (zh) 2019-05-03 2022-02-18 塞尔菲乐有限公司 用于生产血液产品的材料和方法
US20210299179A1 (en) 2020-02-04 2021-09-30 Cellphire, Inc. Methods of treating congenital hemophilia with anti-fibrinolytic loaded platelets
BR112022002892A2 (pt) 2019-08-16 2022-05-24 Cellphire Inc Trombossomos como um agente de reversão de agente antiplaqueta

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU681675B2 (en) * 1993-06-04 1997-09-04 Biotime, Inc. Plasma-like solution
JP2005053841A (ja) * 2003-08-05 2005-03-03 Kyouto Biomedical Science:Kk 皮膚外用剤
AU2005272821B2 (en) * 2004-08-12 2010-09-09 Cellphire, Inc Methods for preparing freeze-dried platelets, compositions comprising freeze-dried platelets, and methods of use
KR20100057641A (ko) * 2007-09-11 2010-05-31 몬도바이오테크 래보래토리즈 아게 인터메딘 ４７ 및 ５３ 펩티드의 치료적 용도
US20110008804A1 (en) * 2007-11-05 2011-01-13 Kain Kevin C Angiopoietin-1 and -2 biomarkers for infectious diseases that compromise endothelial integrity
US20100196461A1 (en) * 2009-01-30 2010-08-05 Simpkins Cuthbert O Resuscitation fluid
US8063020B2 (en) * 2007-12-22 2011-11-22 Simpkins Cuthbert O Resuscitation fluid
US20100055067A1 (en) * 2008-08-26 2010-03-04 Snu R&Db Foundation Perfluorocarbon conjugate as a blood substitute
WO2010046949A1 (ja) * 2008-10-22 2010-04-29 Inui Hiroaki 細胞をガラス化保存する方法および細胞のガラス化保存用容器
KR101410065B1 (ko) * 2011-12-09 2014-06-27 테고사이언스 (주) 세포의 유용물질을 상온에서 안정하게 보존하는 방법

Also Published As

Publication number Publication date
WO2016201081A1 (en) 2016-12-15
EP3307283B1 (en) 2020-09-02
EP3307283A1 (en) 2018-04-18
IL256158A (en) 2018-02-28
AU2016276767A1 (en) 2018-01-04
AU2016276767B2 (en) 2019-04-18
JP2018516965A (ja) 2018-06-28
EP3307283A4 (en) 2018-12-26
US20180169139A1 (en) 2018-06-21
CA2988610A1 (en) 2016-12-15

Similar Documents

Publication Publication Date Title
BR112017026660A2 (pt) composição e kit para tratamento de perda de fluidos que provocam hipotensão e/ou hipovolemia
CO2022002685A2 (es) Nanopartículas lipídicas mejoradas para el suministro de ácidos nucleicos
CL2018001007A1 (es) Composiciones farmacéuticas para terapias combinadas (sol. divisional de n° 201702538).
BR112016024641A2 (pt) obturador antimicrobiano para uso com dispositivos de acesso vascular
MX2021001867A (es) Administracion y monitoreo de oxidio nitrico en fluidos ex vivo.
BR112012023243A2 (pt) sistema para realizar um tratamento de sangue.
CR20160213A (es) Dispositivo para irrigación e insuflación con control de presión dependiente de presión sanguínea
BR112017019279A2 (pt) kits e dispositivos descartáveis para redução de oxigênio e métodos de uso dos mesmos
CL2009000099A1 (es) Sistema de dialisis que comprende una fuente de fluido de dialisis, al menos una bomba para dializado hacia o desde un paciente, un recipiente para recibir fluido de efluente desde el paciente a traves de un tubo de drenaje que incluye un cuerpo al menos parcialmente rigido, con una manilla y una boca, y una celda de carga; metodo de tratamiento de dialisis.
BR112015026006A2 (pt) métodos para o tratamento de câncer com o uso de terapia de combinação com inibidor de cinase tor
AR096518A1 (es) Compuestos poliméricos anfolíticos para aplicaciones subterráneas
BR112014004870A2 (pt) controle de fluxo de dialisado
BR112014031407A2 (pt) método e dispositivo para a monitoração de um tratamento de sangue extracorpóreo de um paciente
BR112012032035A2 (pt) método e dispositivo para o transporte de fluidos para unidade de tratamento de um aparelho de tratamento médico, em particular para o dialisador de um aparelho de diálise.
BR112015022195A8 (pt) sistema e método de diálise peritoneal, instalação para proporcionar trocas de diálise peritoneal, e instalação walk-in
BR112015022433A2 (pt) dispositivos de liberação de droga com componente permeável à droga e métodos
BR112015031271A2 (pt) sistema de entrega de fluido portátil
BR112012025860A2 (pt) reservatório de sangue com sensor de volume ultrassônico
BR112014012522A2 (pt) método para encher um reservatório, reservatório e conjunto para encher um reservatório
BR112014030611A2 (pt) sistema e método de monitoramento e controle de volume de ultrafiltração durante diálise peritoneal usando bioempedância segmentar
GB2526459A (en) In line fluid sampling port
ES2521674T3 (es) Métodos de tratamiento de hiperuricemia y estados patológicos asociados
BR112013021489A2 (pt) dispositivos médicos de lavagem
BR112019024872A2 (pt) aparelho e método para preparar uma solução de diálise peritoneal
BR112022013378A2 (pt) Conjunto de extensão para melhorar permeabilidade de um dispositivo de acesso vascular

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements
B350 Update of information on the portal [chapter 15.35 patent gazette]