BR112017024123A2 - construtos de expressão e métodos de manipulação por engenharia genética de levedura metilotrófica - Google Patents
construtos de expressão e métodos de manipulação por engenharia genética de levedura metilotróficaInfo
- Publication number
- BR112017024123A2 BR112017024123A2 BR112017024123-4A BR112017024123A BR112017024123A2 BR 112017024123 A2 BR112017024123 A2 BR 112017024123A2 BR 112017024123 A BR112017024123 A BR 112017024123A BR 112017024123 A2 BR112017024123 A2 BR 112017024123A2
- Authority
- BR
- Brazil
- Prior art keywords
- methylilotrophic
- yeast
- genetic engineering
- expression constructs
- manipulation methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
- C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
- C07K14/805—Haemoglobins; Myoglobins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/16—Yeasts; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/635—Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Botany (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
a presente invenção refere-se a métodos e materiais para manipulação por engenharia genética de levedura metilotrófica.
Applications Claiming Priority (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562159899P | 2015-05-11 | 2015-05-11 | |
US62/159,899 | 2015-05-11 | ||
US201562183074P | 2015-06-22 | 2015-06-22 | |
US62/183,074 | 2015-06-22 | ||
US201562185921P | 2015-06-29 | 2015-06-29 | |
US62/185,921 | 2015-06-29 | ||
US201562203052P | 2015-08-10 | 2015-08-10 | |
US62/203,052 | 2015-08-10 | ||
US201562220366P | 2015-09-18 | 2015-09-18 | |
US62/220,366 | 2015-09-18 | ||
US201562222388P | 2015-09-23 | 2015-09-23 | |
US62/222,388 | 2015-09-23 | ||
US201562236506P | 2015-10-02 | 2015-10-02 | |
US62/236,506 | 2015-10-02 | ||
US201662313491P | 2016-03-25 | 2016-03-25 | |
US62/313,491 | 2016-03-25 | ||
PCT/US2016/031797 WO2016183163A1 (en) | 2015-05-11 | 2016-05-11 | Expression constructs and methods of genetically engineering methylotrophic yeast |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112017024123A2 true BR112017024123A2 (pt) | 2018-08-07 |
Family
ID=57249545
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112017024123-4A BR112017024123A2 (pt) | 2015-05-11 | 2016-05-11 | construtos de expressão e métodos de manipulação por engenharia genética de levedura metilotrófica |
Country Status (21)
Country | Link |
---|---|
US (5) | US10689656B2 (pt) |
EP (2) | EP3294762B1 (pt) |
JP (4) | JP6831797B2 (pt) |
KR (3) | KR102504198B1 (pt) |
CN (1) | CN107614516A (pt) |
AU (3) | AU2016262494B2 (pt) |
BR (1) | BR112017024123A2 (pt) |
CA (1) | CA2985641A1 (pt) |
DK (1) | DK3294762T3 (pt) |
ES (1) | ES2908463T3 (pt) |
HK (1) | HK1252605A1 (pt) |
HR (1) | HRP20220299T1 (pt) |
HU (1) | HUE058104T2 (pt) |
LT (1) | LT3294762T (pt) |
MX (3) | MX2017014469A (pt) |
NZ (1) | NZ737094A (pt) |
PL (1) | PL3294762T3 (pt) |
PT (1) | PT3294762T (pt) |
RS (1) | RS63099B1 (pt) |
SI (1) | SI3294762T1 (pt) |
WO (1) | WO2016183163A1 (pt) |
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HUE058104T2 (hu) | 2015-05-11 | 2022-07-28 | Impossible Foods Inc | Expressziós konstrukciók és eljárások a metilotróf élesztõ genetikai módosítására |
EP3568408A4 (en) | 2017-01-13 | 2020-12-16 | Bolt Threads, Inc. | ELASTOMER PROTEINS |
WO2018140654A1 (en) * | 2017-01-25 | 2018-08-02 | Altius Institute For Biomedical Sciences | Methods and platform of designing genetic editing tools |
WO2019060759A1 (en) | 2017-09-21 | 2019-03-28 | Dana-Farber Cancer Institute, Inc. | ISOLATION, PRESERVATION, COMPOSITIONS AND USES OF PLANT EXTRACTS JUSTICIA |
US11051532B2 (en) | 2017-09-22 | 2021-07-06 | Impossible Foods Inc. | Methods for purifying protein |
US10221403B1 (en) * | 2018-04-25 | 2019-03-05 | Life Rainbow Biotech Co., Ltd. | Method of preparing zearalenone hydrolase |
CN108913732B (zh) * | 2018-07-31 | 2022-02-08 | 华东理工大学 | 一种莫纳可林j异源生产的方法及应用 |
CN111286520B (zh) * | 2018-12-10 | 2021-05-07 | 上海凯赛生物技术股份有限公司 | 用于发酵生产l-赖氨酸的重组dna、菌株及其应用 |
CN109749948A (zh) * | 2019-03-05 | 2019-05-14 | 天津科技大学 | 一种利用tef1启动子调控黏玉米谷氨酰胺转氨酶表达的重组毕赤酵母菌株及构建方法 |
CN109929769B (zh) * | 2019-03-05 | 2021-07-23 | 天津科技大学 | 一种利用fld1启动子调控黏玉米谷氨酰胺转氨酶表达的重组毕赤酵母菌株及构建方法 |
US11427932B2 (en) | 2019-04-17 | 2022-08-30 | Impossible Foods Inc. | Materials and methods for protein production |
AU2020263580A1 (en) | 2019-04-25 | 2021-11-18 | Impossible Foods Inc. | Strains and methods for production of heme-containing proteins |
US20230220328A1 (en) | 2019-11-27 | 2023-07-13 | Evelo Biosciences, Inc. | Methods and compositions for culturing hemoglobin-dependent bacteria |
EP4090746A4 (en) * | 2020-01-10 | 2024-01-24 | Intron Biotechnology Inc | METHOD FOR PRODUCING SOY LEGHHEMOGLOBIN USING ESCHERICHIA COLI |
US10947552B1 (en) | 2020-09-30 | 2021-03-16 | Alpine Roads, Inc. | Recombinant fusion proteins for producing milk proteins in plants |
EP4222167A1 (en) | 2020-09-30 | 2023-08-09 | Nobell Foods, Inc. | Recombinant milk proteins and food compositions comprising the same |
US10894812B1 (en) | 2020-09-30 | 2021-01-19 | Alpine Roads, Inc. | Recombinant milk proteins |
WO2022072846A2 (en) | 2020-10-02 | 2022-04-07 | Impossible Foods Inc. | Transgenic plants with altered fatty acid profiles and upregulated heme biosynthesis |
WO2022072833A2 (en) | 2020-10-02 | 2022-04-07 | Impossible Foods Inc. | Expression constructs and methods of genetically engineering cells |
AU2021391607A1 (en) * | 2020-12-02 | 2023-06-29 | Planeat Foods Pte. Ltd. | Method of producing globin polypeptide recombinantly and meat substitute food product |
WO2022251166A2 (en) | 2021-05-25 | 2022-12-01 | Evelo Biosciences, Inc. | Bacterial compositions comprising soy hemoglobin |
AU2022369299A1 (en) | 2021-10-19 | 2024-03-14 | Eat Scifi Inc. | Plant base/animal cell hybrid meat substitute |
AU2022415449A1 (en) * | 2021-12-16 | 2024-05-23 | Impossible Foods Inc. | A genetic factor to increase expression of recombinant proteins |
US11931687B2 (en) | 2022-02-15 | 2024-03-19 | Streamline Innovations, Inc. | Gas purification apparatus and method |
KR20230164436A (ko) | 2022-05-25 | 2023-12-04 | 한화솔루션 주식회사 | 야생형 효모 균주를 이용한 헴 고생산 방법 |
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-
2016
- 2016-05-11 HU HUE16793420A patent/HUE058104T2/hu unknown
- 2016-05-11 LT LTEPPCT/US2016/031797T patent/LT3294762T/lt unknown
- 2016-05-11 EP EP16793420.7A patent/EP3294762B1/en active Active
- 2016-05-11 MX MX2017014469A patent/MX2017014469A/es unknown
- 2016-05-11 US US15/573,300 patent/US10689656B2/en active Active
- 2016-05-11 JP JP2017558948A patent/JP6831797B2/ja active Active
- 2016-05-11 DK DK16793420.7T patent/DK3294762T3/da active
- 2016-05-11 ES ES16793420T patent/ES2908463T3/es active Active
- 2016-05-11 NZ NZ737094A patent/NZ737094A/en unknown
- 2016-05-11 HR HRP20220299TT patent/HRP20220299T1/hr unknown
- 2016-05-11 KR KR1020207026647A patent/KR102504198B1/ko active IP Right Grant
- 2016-05-11 PT PT167934207T patent/PT3294762T/pt unknown
- 2016-05-11 BR BR112017024123-4A patent/BR112017024123A2/pt active Search and Examination
- 2016-05-11 KR KR1020237006299A patent/KR20230031993A/ko not_active Application Discontinuation
- 2016-05-11 PL PL16793420T patent/PL3294762T3/pl unknown
- 2016-05-11 RS RS20220256A patent/RS63099B1/sr unknown
- 2016-05-11 SI SI201631500T patent/SI3294762T1/sl unknown
- 2016-05-11 EP EP22151183.5A patent/EP4039695A1/en active Pending
- 2016-05-11 AU AU2016262494A patent/AU2016262494B2/en active Active
- 2016-05-11 CA CA2985641A patent/CA2985641A1/en active Pending
- 2016-05-11 KR KR1020177033598A patent/KR102229968B1/ko active IP Right Grant
- 2016-05-11 WO PCT/US2016/031797 patent/WO2016183163A1/en active Application Filing
- 2016-05-11 CN CN201680029580.4A patent/CN107614516A/zh active Pending
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2017
- 2017-08-16 US US15/678,342 patent/US10273492B2/en active Active
- 2017-08-16 US US15/678,891 patent/US9938327B2/en active Active
- 2017-11-10 MX MX2022013540A patent/MX2022013540A/es unknown
- 2017-11-10 MX MX2022006513A patent/MX2022006513A/es unknown
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2018
- 2018-09-06 US US16/123,121 patent/US11319544B2/en active Active
- 2018-09-17 HK HK18111904.2A patent/HK1252605A1/zh unknown
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2019
- 2019-10-17 AU AU2019250216A patent/AU2019250216B2/en active Active
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2020
- 2020-02-03 JP JP2020016038A patent/JP7308160B2/ja active Active
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2021
- 2021-09-30 JP JP2021161491A patent/JP2022025068A/ja active Pending
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2022
- 2022-01-25 US US17/584,028 patent/US20220290166A1/en active Pending
- 2022-03-03 AU AU2022201465A patent/AU2022201465A1/en active Pending
- 2022-11-04 JP JP2022177137A patent/JP2023022042A/ja active Pending
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