BR112017021669A2 - formulações farmacêuticas orais, método para tratar doenças e uso de ditas formulações - Google Patents
formulações farmacêuticas orais, método para tratar doenças e uso de ditas formulaçõesInfo
- Publication number
- BR112017021669A2 BR112017021669A2 BR112017021669A BR112017021669A BR112017021669A2 BR 112017021669 A2 BR112017021669 A2 BR 112017021669A2 BR 112017021669 A BR112017021669 A BR 112017021669A BR 112017021669 A BR112017021669 A BR 112017021669A BR 112017021669 A2 BR112017021669 A2 BR 112017021669A2
- Authority
- BR
- Brazil
- Prior art keywords
- formulations
- crystals
- treating diseases
- oral pharmaceutical
- pharmaceutical formulations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/541—Organic ions forming an ion pair complex with the pharmacologically or therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Abstract
esta invenção refere-se a formulações farmacêuticas compreendendo 1-(2-tieno-2'-ila-2-oxo-etila)-3-(metanossulfonil hidrazina carbonila)piridínio, seus sais farmaceuticamente aceitáveis, co-cristais de sal e co-cristais, particularmente cloreto de 1-(2-tieno-2'-ila-2-oxo-etila)-3-(metanossulfonil hidrazina carbonila)piridínio. as formulações são adequadas para administração oral, e também compreendem um melhorador de permeabilidade ou uma base adequada, ou uma mistura destes. as formulações desta invenção servem para o tratamento de doenças associadas com produtos finais de glicação avançada.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1475MU2015 | 2015-04-08 | ||
PCT/IB2016/051920 WO2016162787A1 (en) | 2015-04-08 | 2016-04-05 | Pharmaceutical formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112017021669A2 true BR112017021669A2 (pt) | 2018-07-10 |
Family
ID=55808800
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112017021669A BR112017021669A2 (pt) | 2015-04-08 | 2016-04-05 | formulações farmacêuticas orais, método para tratar doenças e uso de ditas formulações |
Country Status (30)
Country | Link |
---|---|
US (1) | US10772879B2 (pt) |
EP (1) | EP3280447B1 (pt) |
JP (1) | JP6736656B2 (pt) |
KR (1) | KR20170134662A (pt) |
CN (1) | CN107530287B (pt) |
AR (1) | AR104185A1 (pt) |
AU (1) | AU2016246124B2 (pt) |
BR (1) | BR112017021669A2 (pt) |
CA (1) | CA2997463A1 (pt) |
CY (1) | CY1121921T1 (pt) |
DK (1) | DK3280447T3 (pt) |
EA (1) | EA037041B1 (pt) |
ES (1) | ES2724629T3 (pt) |
HR (1) | HRP20190783T1 (pt) |
HU (1) | HUE044889T2 (pt) |
IL (1) | IL254794B (pt) |
LT (1) | LT3280447T (pt) |
MX (1) | MX2017012942A (pt) |
MY (1) | MY182008A (pt) |
PH (1) | PH12017501829A1 (pt) |
PL (1) | PL3280447T3 (pt) |
PT (1) | PT3280447T (pt) |
RS (1) | RS58708B1 (pt) |
SG (1) | SG11201708142XA (pt) |
SI (1) | SI3280447T1 (pt) |
TR (1) | TR201906476T4 (pt) |
TW (1) | TWI713512B (pt) |
UA (1) | UA123051C2 (pt) |
WO (1) | WO2016162787A1 (pt) |
ZA (1) | ZA201707094B (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3169368A1 (en) | 2012-06-15 | 2014-01-09 | Nova Southeastern University | Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine |
EP3888642A1 (en) | 2013-03-22 | 2021-10-06 | Nova Southeastern University | Epinephrine fine particles and methods for use thereof for treatment of conditions responsive to epinephrine |
CA3116730A1 (en) * | 2018-10-19 | 2020-04-23 | Nova Southeastern University | Sublingual epinephrine compositions including ph-modifying excipients and penetration enhancers and methods for use thereof |
KR102330597B1 (ko) * | 2020-04-17 | 2021-11-26 | 보령제약 주식회사 | 무정형의 엠파글리플로진을 포함하는 안정성이 향상된 신규 약제학적 제형 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE386508T1 (de) * | 1999-02-22 | 2008-03-15 | Merrion Res I Ltd | Feste orale dosierungsform enthaltend einen resorptionsverstärker |
PT1222171E (pt) * | 1999-10-06 | 2004-07-30 | Torrent Pharmaceuticals Ltd | Derivados do piridinio para o tratamento das doencas vasculares relacionadas com o envelhecimento e a diabetes e processo para a sua preparacao e utilizacao terapeutica destes derivados |
ES2243389T3 (es) | 2001-03-21 | 2005-12-01 | Torrent Pharmaceuticals Ltd | Compuestos de piridinio utiles para el tratamiento de enfermedades relacionadas con los age. |
MX2008011227A (es) | 2006-03-03 | 2009-02-10 | Torrent Pharmaceuticals Ltd | Receptores antagonistas de accion nueva y doble en los receptores at1 y eta. |
JP2009023932A (ja) * | 2007-07-18 | 2009-02-05 | Tama Tlo Kk | N−メチルピリジニウム化合物を有効成分として含有する抗ウイルス剤、それを含有する、抗ウイルス組成物、食餌及び動物用飼料 |
BRPI0907650A2 (pt) * | 2008-01-25 | 2015-07-21 | Torrent Pharmaceuticals Ltd | Composições farmacêuticas compreendendo degradadores de produtos finais de glicosilação avançada (ages) e drogas adjuvantes como drogas anti-hipertensivas, antidiabéticas e etc |
CN101574343B (zh) * | 2008-05-07 | 2011-06-01 | 吉林大学 | 一种治疗糖尿病的药物组合物 |
WO2010128528A2 (en) * | 2009-05-07 | 2010-11-11 | Torrent Pharmaceuticals Limited | Novel heterocyclic compounds |
JP2013514976A (ja) * | 2009-12-16 | 2013-05-02 | ノッド ファーマシューティカルズ, インコーポレイテッド | 経口薬物送達のための組成物および方法 |
CN104069066B (zh) * | 2013-03-25 | 2017-04-19 | 吉林大学 | 黄癸固体分散体及其在治疗糖尿病及并发症中的应用 |
-
2016
- 2016-04-05 LT LTEP16718474.6T patent/LT3280447T/lt unknown
- 2016-04-05 RS RS20190537A patent/RS58708B1/sr unknown
- 2016-04-05 WO PCT/IB2016/051920 patent/WO2016162787A1/en active Application Filing
- 2016-04-05 SG SG11201708142XA patent/SG11201708142XA/en unknown
- 2016-04-05 US US15/564,720 patent/US10772879B2/en active Active
- 2016-04-05 PL PL16718474T patent/PL3280447T3/pl unknown
- 2016-04-05 TR TR2019/06476T patent/TR201906476T4/tr unknown
- 2016-04-05 AU AU2016246124A patent/AU2016246124B2/en not_active Ceased
- 2016-04-05 UA UAA201710864A patent/UA123051C2/uk unknown
- 2016-04-05 EP EP16718474.6A patent/EP3280447B1/en active Active
- 2016-04-05 PT PT16718474T patent/PT3280447T/pt unknown
- 2016-04-05 JP JP2018503835A patent/JP6736656B2/ja not_active Expired - Fee Related
- 2016-04-05 CA CA2997463A patent/CA2997463A1/en not_active Abandoned
- 2016-04-05 BR BR112017021669A patent/BR112017021669A2/pt not_active Application Discontinuation
- 2016-04-05 MY MYPI2017001475A patent/MY182008A/en unknown
- 2016-04-05 MX MX2017012942A patent/MX2017012942A/es unknown
- 2016-04-05 CN CN201680020704.2A patent/CN107530287B/zh not_active Expired - Fee Related
- 2016-04-05 DK DK16718474.6T patent/DK3280447T3/da active
- 2016-04-05 SI SI201630246T patent/SI3280447T1/sl unknown
- 2016-04-05 HU HUE16718474 patent/HUE044889T2/hu unknown
- 2016-04-05 AR ARP160100918A patent/AR104185A1/es unknown
- 2016-04-05 EA EA201792237A patent/EA037041B1/ru unknown
- 2016-04-05 KR KR1020177032035A patent/KR20170134662A/ko not_active Application Discontinuation
- 2016-04-05 ES ES16718474T patent/ES2724629T3/es active Active
- 2016-04-06 TW TW105110715A patent/TWI713512B/zh active
-
2017
- 2017-09-28 IL IL254794A patent/IL254794B/en active IP Right Grant
- 2017-10-06 PH PH12017501829A patent/PH12017501829A1/en unknown
- 2017-10-19 ZA ZA2017/07094A patent/ZA201707094B/en unknown
-
2019
- 2019-04-26 HR HRP20190783TT patent/HRP20190783T1/hr unknown
- 2019-05-03 CY CY20191100471T patent/CY1121921T1/el unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |