BR112017001444A2 - ?método para detectar pelo menos um analito em uma amostra de teste, elemento sensor, dispositivo de teste, sistema de teste e uso do elemento sensor? - Google Patents
?método para detectar pelo menos um analito em uma amostra de teste, elemento sensor, dispositivo de teste, sistema de teste e uso do elemento sensor?Info
- Publication number
- BR112017001444A2 BR112017001444A2 BR112017001444A BR112017001444A BR112017001444A2 BR 112017001444 A2 BR112017001444 A2 BR 112017001444A2 BR 112017001444 A BR112017001444 A BR 112017001444A BR 112017001444 A BR112017001444 A BR 112017001444A BR 112017001444 A2 BR112017001444 A2 BR 112017001444A2
- Authority
- BR
- Brazil
- Prior art keywords
- chemical matrix
- electrode
- active
- analyte
- test
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
- C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
- G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Electrochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Emergency Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Ecology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Nanotechnology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
refere-se a um método para detectar pelo menos um analito em uma amostra teste, que compreende as etapas: a) colocar a amostra de teste em contato (i) com uma matriz química ativa (116) que altera pelo menos uma propriedade eletroquímica dependente de uma atividade enzimática ativa na presença do analito, a matriz química ativa faz contato com um primeiro eletrodo (112); e (ii) com uma matriz química inativa (118), matriz química inativa faz contato com um segundo eletrodo (114), b) fecha um circuito elétrico que inclui o primeiro eletrodo (112), o segundo eletrodo (114) e a matriz química ativa (116) e matriz química inativa (118), seguido pela determinação de um primeiro valor de pelo menos uma propriedade eletroquímica, c) inverter a polaridade elétrica do circuito elétrico de b), seguido pela determinação de um segundo valor de pelo menos uma propriedade eletroquímica, d) detectar pelo menos um analito com base no primeiro valor e no dito segundo valor. um dispositivo de teste e um sistema de teste adaptado que usa o método. um elemento sensor (110) que determina pelo menos um analito, compreende um par de eletrodos (112, 114) e pelo menos uma matriz química ativa e uma inativa, (116, 118), cuja matriz química ativa (116) altera pelo menos uma propriedade eletroquímica dependente de uma atividade enzimática ativa, (i) o par de eletrodos (112, 114) consiste em dois eletrodos eletricamente isolados de outros eletrodos, (ii) matriz química ativa (116) compreende atividade enzimática e matriz química inativa (118) não compreende a atividade enzimática, (iii) um primeiro eletrodo (112) do par de eletrodos faz contato com a matriz química ativa (116) e um segundo eletrodo (114) do par de eletrodos faz contato com a matriz química inativa (118).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14182141 | 2014-08-25 | ||
| EP14182141.3 | 2014-08-25 | ||
| PCT/EP2015/069393 WO2016030346A2 (en) | 2014-08-25 | 2015-08-25 | Interference compensating two electrodes test strip |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112017001444A2 true BR112017001444A2 (pt) | 2017-12-05 |
| BR112017001444B1 BR112017001444B1 (pt) | 2022-08-16 |
Family
ID=51429047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112017001444-0A BR112017001444B1 (pt) | 2014-08-25 | 2015-08-25 | Método para detectar pelo menos um analito em uma amostra de teste, elemento sensor, dispositivo de teste, sistema de teste, uso do elemento sensor e portador de dados |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10590458B2 (pt) |
| EP (2) | EP3186385B1 (pt) |
| JP (2) | JP6639479B2 (pt) |
| KR (1) | KR101950615B1 (pt) |
| CN (2) | CN113444764B (pt) |
| BR (1) | BR112017001444B1 (pt) |
| ES (2) | ES2756714T3 (pt) |
| PL (1) | PL3597765T3 (pt) |
| WO (1) | WO2016030346A2 (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3308152B1 (en) | 2015-06-15 | 2019-07-24 | Roche Diagnostics GmbH | Method for electrochemically detecting at least one analyte in a sample of a body fluid |
| PL3220137T3 (pl) | 2016-03-14 | 2019-07-31 | F. Hoffmann-La Roche Ag | Sposób wykrywania udziału zakłócającego w biosensorze |
| WO2017173255A1 (en) * | 2016-03-31 | 2017-10-05 | Polymer Technology Systems, Inc. | Systems and methods for electrochemical creatinine assays |
| CA3028348A1 (en) * | 2016-07-12 | 2018-01-18 | Ascensia Diabetes Care Holdings Ag | Method for electrochemical analysis by use of alternating output signals from two electrodes |
| CN109804240A (zh) * | 2016-10-05 | 2019-05-24 | 豪夫迈·罗氏有限公司 | 用于多分析物诊断测试元件的检测试剂和电极布置以及其使用方法 |
| US20200300836A1 (en) * | 2018-10-12 | 2020-09-24 | Polymer Technology Systems, Inc. | Systems and methods for point-of-care detection of potassium |
| CN109270145B (zh) * | 2018-11-20 | 2021-09-17 | 三诺生物传感股份有限公司 | 一种双电极的电化学试条的测试方法 |
| CN109856128A (zh) * | 2018-12-24 | 2019-06-07 | 迪瑞医疗科技股份有限公司 | 一种抗坏血酸干扰的尿葡萄糖检测试纸及其制备方法 |
| KR102255442B1 (ko) * | 2019-03-29 | 2021-05-24 | 동우 화인켐 주식회사 | 바이오 센서 |
| CA3152919A1 (en) * | 2019-09-30 | 2021-04-08 | Stanley Zhen-Jin TEO | Electrochemical sensor for analysis of beverages |
| USD1016324S1 (en) * | 2020-07-08 | 2024-02-27 | NanoCav, LLC | Biological cell processing chip |
| ES2915406B2 (es) * | 2020-12-21 | 2024-03-14 | Bioquochem S L | Metodo para medir una concentracion de un compuesto de analisis o una actividad enzimatica en una muestra compleja mediante la cuantificacion de peroxido de hidrogeno de forma selectiva |
| USD983405S1 (en) * | 2021-04-15 | 2023-04-11 | Cytoaurora Biotechnologies, Inc. | Microfluidic chip |
| KR20230099331A (ko) * | 2021-12-27 | 2023-07-04 | 주식회사 큐에스택 | 진단 스트립의 모니터링 전극 |
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| JPS63122942A (ja) | 1986-11-12 | 1988-05-26 | Kanzaki Paper Mfg Co Ltd | 酵素電極の活性化方法 |
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| US5494562A (en) * | 1994-06-27 | 1996-02-27 | Ciba Corning Diagnostics Corp. | Electrochemical sensors |
| JPH09101280A (ja) | 1995-10-05 | 1997-04-15 | Casio Comput Co Ltd | バイオセンサ |
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| JPH10170471A (ja) | 1996-12-06 | 1998-06-26 | Casio Comput Co Ltd | バイオセンサ |
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2015
- 2015-08-25 BR BR112017001444-0A patent/BR112017001444B1/pt active IP Right Grant
- 2015-08-25 JP JP2017510663A patent/JP6639479B2/ja active Active
- 2015-08-25 CN CN202110616477.2A patent/CN113444764B/zh active Active
- 2015-08-25 ES ES15760115T patent/ES2756714T3/es active Active
- 2015-08-25 EP EP15760115.4A patent/EP3186385B1/en active Active
- 2015-08-25 KR KR1020177005342A patent/KR101950615B1/ko active IP Right Grant
- 2015-08-25 WO PCT/EP2015/069393 patent/WO2016030346A2/en active Application Filing
- 2015-08-25 EP EP19197046.6A patent/EP3597765B1/en active Active
- 2015-08-25 ES ES19197046T patent/ES2883115T3/es active Active
- 2015-08-25 PL PL19197046T patent/PL3597765T3/pl unknown
- 2015-08-25 CN CN201580046275.1A patent/CN106795549B/zh active Active
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2017
- 2017-02-24 US US15/442,202 patent/US10590458B2/en active Active
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2019
- 2019-12-24 JP JP2019232271A patent/JP7003103B2/ja active Active
-
2020
- 2020-01-07 US US16/735,773 patent/US11473118B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN106795549A (zh) | 2017-05-31 |
| US11473118B2 (en) | 2022-10-18 |
| ES2756714T3 (es) | 2020-04-27 |
| KR101950615B1 (ko) | 2019-02-20 |
| KR20170036072A (ko) | 2017-03-31 |
| EP3186385B1 (en) | 2019-09-18 |
| US10590458B2 (en) | 2020-03-17 |
| WO2016030346A2 (en) | 2016-03-03 |
| JP6639479B2 (ja) | 2020-02-05 |
| WO2016030346A3 (en) | 2016-08-11 |
| EP3597765B1 (en) | 2021-06-02 |
| US20200140914A1 (en) | 2020-05-07 |
| JP7003103B2 (ja) | 2022-01-20 |
| CN113444764A (zh) | 2021-09-28 |
| JP2017525966A (ja) | 2017-09-07 |
| BR112017001444B1 (pt) | 2022-08-16 |
| EP3186385A2 (en) | 2017-07-05 |
| JP2020064070A (ja) | 2020-04-23 |
| PL3597765T3 (pl) | 2021-11-08 |
| US20170240945A1 (en) | 2017-08-24 |
| EP3597765A1 (en) | 2020-01-22 |
| CN113444764B (zh) | 2024-04-19 |
| ES2883115T3 (es) | 2021-12-07 |
| CN106795549B (zh) | 2021-06-22 |
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| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
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Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 25/08/2015, OBSERVADAS AS CONDICOES LEGAIS |