BR112016013801A2 - SS-HINOQUITIOL DERIVATIVES AND THEIR APPLICATIONS IN THE PREPARATION OF ANIMAL ANTIBACTERIAL AGENTS AND ANTIBACTERIAL GROWTH PROMOTERS USED IN FOOD - Google Patents

SS-HINOQUITIOL DERIVATIVES AND THEIR APPLICATIONS IN THE PREPARATION OF ANIMAL ANTIBACTERIAL AGENTS AND ANTIBACTERIAL GROWTH PROMOTERS USED IN FOOD

Info

Publication number
BR112016013801A2
BR112016013801A2 BR112016013801A BR112016013801A BR112016013801A2 BR 112016013801 A2 BR112016013801 A2 BR 112016013801A2 BR 112016013801 A BR112016013801 A BR 112016013801A BR 112016013801 A BR112016013801 A BR 112016013801A BR 112016013801 A2 BR112016013801 A2 BR 112016013801A2
Authority
BR
Brazil
Prior art keywords
hinoquitiol
derivatives
antibacterial
food
preparation
Prior art date
Application number
BR112016013801A
Other languages
Portuguese (pt)
Inventor
Xianfeng Peng
Zonghua Qin
Original Assignee
Guangzhou Insighter Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangzhou Insighter Biotechnology Co Ltd filed Critical Guangzhou Insighter Biotechnology Co Ltd
Publication of BR112016013801A2 publication Critical patent/BR112016013801A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/717—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups a keto group being part of a seven- to twelve-membered ring
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
    • A01N35/04—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing aldehyde or keto groups, or thio analogues thereof, directly attached to an aromatic ring system, e.g. acetophenone; Derivatives thereof, e.g. acetals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/111—Aromatic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/195—Antibiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/723—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Birds (AREA)
  • General Health & Medical Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Fodder In General (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)

Abstract

DERIVADOS DE ß-HINOQUITIOL E SUAS APLICAÇÕES NA PREPARAÇÃO DE AGENTES ANTIBACTERIANOS DE ANIMAIS E PROMOTORES DE CRESCIMENTO ANTIBACTERIANOS UTILIZADOS NA ALIMENTAÇÃO. A presente invenção descreve derivados de ß- hinoquitiol e sua aplicação na preparação de agentes antibacterianos de animais e promotores de crescimento antibacterianos utilizados em alimentos para animais, possuindo os derivados de ß-hinoquitiol uma fórmula estrutural mostrada na fórmula (I): em que, R é n-propilo, n-pentilo, benzil, sec-butilo, etilo, n-butilo, pclorobenzil, p-fluorobenzil, n-octilo, 1-fluoropropilo ou n-tetradecilo; os compostos da presente invenção, como mostrado na fórmula I, apresentam uma baixa toxicidade ou não toxicidade em aves domésticas, são mais seguros e têm propriedades fortes de promoção do crescimento em comparação com todos os compostos patenteados no presente, e, portanto, são mais apropriados para serem usados como promotores de crescimento em alimentação, sendo que a presente invenção tem uma perspectiva muito boa para aplicação na indústria de cultivo.ß-HINOQUITIOL DERIVATIVES AND THEIR APPLICATIONS IN THE PREPARATION OF ANIMAL ANTIBACTERIAL AGENTS AND ANTIBACTERIAL GROWTH PROMOTERS USED IN FOOD. The present invention describes ß-hinoquitiol derivatives and their application in the preparation of animal antibacterial agents and antibacterial growth promoters used in animal feed, the ß-hinoquitiol derivatives having a structural formula shown in formula (I): wherein, R is n-propyl, n-pentyl, benzyl, sec-butyl, ethyl, n-butyl, p-chlorobenzyl, p-fluorobenzyl, n-octyl, 1-fluoropropyl or n-tetradecyl; the compounds of the present invention, as shown in formula I, show a low toxicity or non-toxicity in poultry, are safer and have strong growth-promoting properties compared to all compounds patented at present, and therefore are more suitable to be used as growth promoters in food, and the present invention has a very good prospect for application in the cultivation industry.

BR112016013801A 2013-12-31 2014-01-14 SS-HINOQUITIOL DERIVATIVES AND THEIR APPLICATIONS IN THE PREPARATION OF ANIMAL ANTIBACTERIAL AGENTS AND ANTIBACTERIAL GROWTH PROMOTERS USED IN FOOD BR112016013801A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201310751901.XA CN103739471B (en) 2013-12-31 2013-12-31 β-chamenol derivative and the application in preparation animal specific antiseptic-germicide and feeding antimicrobial growth promotor thereof
PCT/CN2014/070603 WO2015100799A1 (en) 2013-12-31 2014-01-14 Β-hinokitol derivative and uses thereof in preparation of special antibacterial agent for animal and antimicrobial growth promoter for feed

Publications (1)

Publication Number Publication Date
BR112016013801A2 true BR112016013801A2 (en) 2017-08-08

Family

ID=50496564

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016013801A BR112016013801A2 (en) 2013-12-31 2014-01-14 SS-HINOQUITIOL DERIVATIVES AND THEIR APPLICATIONS IN THE PREPARATION OF ANIMAL ANTIBACTERIAL AGENTS AND ANTIBACTERIAL GROWTH PROMOTERS USED IN FOOD

Country Status (6)

Country Link
US (1) US20160316790A1 (en)
EP (1) EP3085685A4 (en)
CN (2) CN104922100B (en)
BR (1) BR112016013801A2 (en)
CA (1) CA2934581A1 (en)
WO (1) WO2015100799A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109512999B (en) * 2016-03-04 2022-05-10 广州英赛特生物技术有限公司 Use of aliphatic alcohols containing oxygenated hydrocarbon derivatives as a synergist for polymyxins

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5984809A (en) * 1982-11-08 1984-05-16 Shiseido Co Ltd The first agent for permanent waving
JPS5984810A (en) * 1982-11-08 1984-05-16 Shiseido Co Ltd The first agent for permanent waving
JPH02207758A (en) * 1989-02-09 1990-08-17 Taiyo Kagaku Co Ltd Feed for pisciculture
DE19510229A1 (en) * 1995-03-23 1996-09-26 Keppler Bernhard K Priv Doz Dr Bismuth complexes with tropolone, thiosemicarbazone or di:thiocarbazonic acid ester cpds.
CN1124132C (en) * 1995-06-30 2003-10-15 株式会社皮爱肤 Antibacterial/bactericidal/antiseptic agent, dermatologic preparation and detergent composition
US6387417B1 (en) * 1999-08-23 2002-05-14 Kazuo Iwai Bactericide against vancomycin resistant enterococcus
WO2001089504A1 (en) * 2000-05-25 2001-11-29 Nippon Shinyaku Co., Ltd. Tropolone derivatives and pharmaceutical compositions
EP2864311A4 (en) * 2012-06-22 2015-12-02 Univ Connecticut Substituted tropolone derivatives and methods of use

Also Published As

Publication number Publication date
CA2934581A1 (en) 2015-07-09
CN104922100B (en) 2018-04-06
CN104922100A (en) 2015-09-23
EP3085685A1 (en) 2016-10-26
CN103739471B (en) 2016-04-13
WO2015100799A1 (en) 2015-07-09
EP3085685A4 (en) 2016-12-28
CN103739471A (en) 2014-04-23
US20160316790A1 (en) 2016-11-03

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: C07C 49/717 (2006.01), A61K 31/122 (2006.01)