BR112016004510A2 - composições bioativas deriváveis de concentrados de plaquetas e métodos para preparar e usar as mesmas - Google Patents
composições bioativas deriváveis de concentrados de plaquetas e métodos para preparar e usar as mesmasInfo
- Publication number
- BR112016004510A2 BR112016004510A2 BR112016004510A BR112016004510A BR112016004510A2 BR 112016004510 A2 BR112016004510 A2 BR 112016004510A2 BR 112016004510 A BR112016004510 A BR 112016004510A BR 112016004510 A BR112016004510 A BR 112016004510A BR 112016004510 A2 BR112016004510 A2 BR 112016004510A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- bioactive
- preparing
- compositions derived
- bioactive compositions
- Prior art date
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/19—Platelets; Megacaryocytes
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A61K38/18—Growth factors; Growth regulators
- A61K38/1808—Epidermal growth factor [EGF] urogastrone
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- A61K38/1825—Fibroblast growth factor [FGF]
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- A61K38/1841—Transforming growth factor [TGF]
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Abstract
resumo composições bioativas deriváveis de concentrados de plaquetas e métodos para preparar e usar as mesmas a presente divulgação proporciona uma composição compreendendo uma fração bioativa derivada de um concentrado de plaqueta, métodos de fazer a fração bioativa e meio de cultura suplementado com a fração bioativa. frações bioativas preferidas têm concentrações relativamente baixas de fibrinogênio, embora man-tendo fatores de crescimento nativos em quantidades e razões benéficas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US201361870686P | 2013-08-27 | 2013-08-27 | |
PCT/US2014/052885 WO2015031465A1 (en) | 2013-08-27 | 2014-08-27 | Bioactive compositions derivable from platelet concentrates, and methods for preparing and using same |
Publications (1)
Publication Number | Publication Date |
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BR112016004510A2 true BR112016004510A2 (pt) | 2017-09-12 |
Family
ID=51541312
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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BR112016004510A BR112016004510A2 (pt) | 2013-08-27 | 2014-08-27 | composições bioativas deriváveis de concentrados de plaquetas e métodos para preparar e usar as mesmas |
Country Status (11)
Country | Link |
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US (2) | US9757430B2 (pt) |
EP (1) | EP3038628B1 (pt) |
JP (1) | JP6649257B2 (pt) |
KR (1) | KR102313054B1 (pt) |
CN (2) | CN105636599A (pt) |
AU (1) | AU2014312421A1 (pt) |
BR (1) | BR112016004510A2 (pt) |
CA (1) | CA2922205C (pt) |
ES (1) | ES2837854T3 (pt) |
MX (1) | MX2016002492A (pt) |
WO (1) | WO2015031465A1 (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
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EP2723354B3 (en) * | 2011-06-27 | 2021-03-24 | Emory University | Compositions, uses, and preparation of platelet lysates |
DE102015205293A1 (de) * | 2015-03-24 | 2016-09-29 | Marc Schrott | Verfahren zur Herstellung von Augentropfen |
FR3036707B1 (fr) * | 2015-05-29 | 2019-05-17 | Maco Pharma | Procede de sterilisation d'un lysat plaquettaire |
US11326144B2 (en) | 2015-05-29 | 2022-05-10 | Powder Life Llc | Particulate lyophilized platelet lysate compositions |
ES2633815B1 (es) * | 2016-03-23 | 2018-07-06 | Biotechnology Institute I Mas D, S.L. | Formulación de aplicación tópica, rica en plaquetas y/o factores de crecimiento y un método de preparación de la misma |
WO2018091713A1 (en) * | 2016-11-18 | 2018-05-24 | Consumed Cvba | A method for preparing a growth factors containing platelet releasate |
CN110891582A (zh) * | 2017-06-16 | 2020-03-17 | 里尔大学中心医院 | 制备混合人血小板裂解液的方法、混合人血小板裂解液及其用于治疗神经***疾病的用途 |
EP4190892A1 (en) * | 2020-07-31 | 2023-06-07 | Rainbow Inc. | Platelet lysate derived from autologous platelets |
WO2022181798A1 (ja) * | 2021-02-26 | 2022-09-01 | 株式会社同仁がん免疫研究所 | 成長因子混合物を調整する方法 |
KR102656373B1 (ko) * | 2021-06-25 | 2024-04-12 | 서울대학교병원 | 난소 조직 이식용 하이드로겔 |
EP4276173A1 (en) * | 2022-05-10 | 2023-11-15 | Stemmatters, Biotecnologia e Medicina Regenerativa, S.A. | Stable human platelet lysate composition, methods and uses thereof |
CN115125191B (zh) * | 2022-08-22 | 2023-10-13 | 浙江绿蔻生物技术有限公司 | 成纤维细胞转化培养基及其应用、成纤维细胞的制备方法 |
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US4520107A (en) * | 1982-09-28 | 1985-05-28 | Polydex Chemicals Ltd. | Tissue culture and cell growth-promoting material and its method of manufacture |
SE8801537D0 (sv) * | 1988-04-26 | 1988-04-26 | Ellco Food Ab | Cellodlingsmedium samt forfarande for dess framstellning |
SE0501462L (sv) * | 2005-06-23 | 2006-09-26 | Proliff Ab | Förfarande för framställning av blodplättslysat |
EP2069479A1 (en) | 2006-09-18 | 2009-06-17 | Medizinische Universität Graz | Plasma-free platelet lysate for use as a supplement in cell cultures and for the preparation of cell therapeutics |
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WO2011127071A1 (en) * | 2010-04-05 | 2011-10-13 | Allan Mishra | Platelet rich plasma formulations |
PT2611906T (pt) | 2010-08-31 | 2024-04-16 | Gallant Pet Inc | Terapias sistémicas com células estaminais alogénicas para tratamento de doenças em gatos e cães |
IL210162A0 (en) | 2010-12-21 | 2011-03-31 | Omrix Biopharmaceuticals | Viral inactivated platelet extract, use and preparation thereof |
EP2723354B3 (en) * | 2011-06-27 | 2021-03-24 | Emory University | Compositions, uses, and preparation of platelet lysates |
US8430521B2 (en) * | 2011-07-02 | 2013-04-30 | Jet Motor Limited | Pool lighting assembly |
EP2733200A1 (en) * | 2012-11-15 | 2014-05-21 | Biorigen International SA | Cell culture supplements |
HUE056391T2 (hu) | 2013-02-12 | 2022-02-28 | Lacerta Tech Inc | Vérlemezkedús fibrin szérumfrakciója |
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JP6649257B2 (ja) | 2020-02-19 |
EP3038628A1 (en) | 2016-07-06 |
EP3038628B1 (en) | 2020-09-23 |
WO2015031465A1 (en) | 2015-03-05 |
US20150064133A1 (en) | 2015-03-05 |
AU2014312421A1 (en) | 2016-04-14 |
CN105636599A (zh) | 2016-06-01 |
ES2837854T3 (es) | 2021-07-01 |
JP2016529283A (ja) | 2016-09-23 |
MX2016002492A (es) | 2016-12-09 |
CA2922205A1 (en) | 2015-03-05 |
CA2922205C (en) | 2021-08-17 |
KR102313054B1 (ko) | 2021-10-18 |
US9757430B2 (en) | 2017-09-12 |
US20170319622A1 (en) | 2017-11-09 |
CN114392274A (zh) | 2022-04-26 |
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