BR112016004510A2 - composições bioativas deriváveis de concentrados de plaquetas e métodos para preparar e usar as mesmas - Google Patents

composições bioativas deriváveis de concentrados de plaquetas e métodos para preparar e usar as mesmas

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Publication number
BR112016004510A2
BR112016004510A2 BR112016004510A BR112016004510A BR112016004510A2 BR 112016004510 A2 BR112016004510 A2 BR 112016004510A2 BR 112016004510 A BR112016004510 A BR 112016004510A BR 112016004510 A BR112016004510 A BR 112016004510A BR 112016004510 A2 BR112016004510 A2 BR 112016004510A2
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BR
Brazil
Prior art keywords
methods
bioactive
preparing
compositions derived
bioactive compositions
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Application number
BR112016004510A
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English (en)
Inventor
Gregory Taylor Christopher
John Woods Erick
Original Assignee
Cook General Biotechnology Llc
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Application filed by Cook General Biotechnology Llc filed Critical Cook General Biotechnology Llc
Publication of BR112016004510A2 publication Critical patent/BR112016004510A2/pt

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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/19Platelets; Megacaryocytes
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    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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    • A61K38/18Growth factors; Growth regulators
    • A61K38/1841Transforming growth factor [TGF]
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Abstract

resumo composições bioativas deriváveis de concentrados de plaquetas e métodos para preparar e usar as mesmas a presente divulgação proporciona uma composição compreendendo uma fração bioativa derivada de um concentrado de plaqueta, métodos de fazer a fração bioativa e meio de cultura suplementado com a fração bioativa. frações bioativas preferidas têm concentrações relativamente baixas de fibrinogênio, embora man-tendo fatores de crescimento nativos em quantidades e razões benéficas.
BR112016004510A 2013-08-27 2014-08-27 composições bioativas deriváveis de concentrados de plaquetas e métodos para preparar e usar as mesmas BR112016004510A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361870686P 2013-08-27 2013-08-27
PCT/US2014/052885 WO2015031465A1 (en) 2013-08-27 2014-08-27 Bioactive compositions derivable from platelet concentrates, and methods for preparing and using same

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BR112016004510A2 true BR112016004510A2 (pt) 2017-09-12

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US (2) US9757430B2 (pt)
EP (1) EP3038628B1 (pt)
JP (1) JP6649257B2 (pt)
KR (1) KR102313054B1 (pt)
CN (2) CN105636599A (pt)
AU (1) AU2014312421A1 (pt)
BR (1) BR112016004510A2 (pt)
CA (1) CA2922205C (pt)
ES (1) ES2837854T3 (pt)
MX (1) MX2016002492A (pt)
WO (1) WO2015031465A1 (pt)

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