BR112015031589A2 - método para a fabricação de um produto moldado de ácido hialurônico reticulado - Google Patents

método para a fabricação de um produto moldado de ácido hialurônico reticulado

Info

Publication number
BR112015031589A2
BR112015031589A2 BR112015031589A BR112015031589A BR112015031589A2 BR 112015031589 A2 BR112015031589 A2 BR 112015031589A2 BR 112015031589 A BR112015031589 A BR 112015031589A BR 112015031589 A BR112015031589 A BR 112015031589A BR 112015031589 A2 BR112015031589 A2 BR 112015031589A2
Authority
BR
Brazil
Prior art keywords
hyaluronic acid
molded product
manufacturing
cross
acid molded
Prior art date
Application number
BR112015031589A
Other languages
English (en)
Inventor
Öhrlund Ake
Helander Kenne Anne
Karlsson Morgan
Original Assignee
Galderma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Sa filed Critical Galderma Sa
Publication of BR112015031589A2 publication Critical patent/BR112015031589A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/042—Gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F9/00—Artificial filaments or the like of other substances; Manufacture thereof; Apparatus specially adapted for the manufacture of carbon filaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91—Injection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Birds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Dispersion Chemistry (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Textile Engineering (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Inorganic Chemistry (AREA)

Abstract

resumo “método para a fabricação de um produto moldado de ácido hialurônico reticulado”. um método para a fabricação de um produto moldado de ácido hialurônico reticulado, que compreende a etapa de submeter um substrato de ácido hialurônico precipitado não-reticulado na forma desejada a uma única reação de reticulação em um meio líquido com um ph de 11,5 ou superior e que compreende um ou mais agente(s) de reticulação polifuncional e uma quantidade de um ou mais solvente(s) orgânicos que dá condições de precipitação ao ácido hialurônico, sob condições adequadas para obter um produto moldado de ácido hialurônico reticulado precipitado, com um grau de modificação de 1-40 unidades de agente de reticulação por 1000 unidades de dissacarídeo.
BR112015031589A 2013-06-28 2013-06-28 método para a fabricação de um produto moldado de ácido hialurônico reticulado BR112015031589A2 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2013/063716 WO2014206500A1 (en) 2013-06-28 2013-06-28 Method for manufacturing a shaped cross-linked hyaluronic acid product

Publications (1)

Publication Number Publication Date
BR112015031589A2 true BR112015031589A2 (pt) 2017-07-25

Family

ID=48703545

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015031589A BR112015031589A2 (pt) 2013-06-28 2013-06-28 método para a fabricação de um produto moldado de ácido hialurônico reticulado

Country Status (12)

Country Link
US (4) US10077321B2 (pt)
EP (2) EP3013865B1 (pt)
JP (1) JP6434003B2 (pt)
KR (1) KR102048395B1 (pt)
CN (2) CN105473622B (pt)
AU (1) AU2013396752B2 (pt)
BR (1) BR112015031589A2 (pt)
CA (1) CA2916119A1 (pt)
HK (1) HK1224314A1 (pt)
MX (1) MX369409B (pt)
RU (1) RU2640865C2 (pt)
WO (1) WO2014206500A1 (pt)

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US11021580B2 (en) 2015-07-27 2021-06-01 Galderma Holding SA Process for efficient cross-linking of hyaluronic acid
KR101709608B1 (ko) * 2015-09-03 2017-03-09 (주)진우바이오 용융 방사에 의한 히알루론산염 파이버의 제조방법 및 이로부터 제조된 히알루론산염 파이버
EP3350240B1 (en) * 2015-09-18 2023-08-09 Arkema, Inc. Polyol pre-mixes having improved shelf life
KR20170090965A (ko) * 2016-01-29 2017-08-08 한미약품 주식회사 복합 히알루론산 가교물 및 그 제조방법
US20190247547A1 (en) * 2016-10-18 2019-08-15 Aarhus Universitet Printed hyaluronic acid scaffolds
WO2018122342A1 (en) * 2016-12-29 2018-07-05 Nestlé Skin Health Sa Micro- or nanoparticular multilamellar vesicles, compositions comprising the same and method for their use in skin care
WO2018122343A1 (en) 2016-12-29 2018-07-05 Nestlé Skin Health Sa Micro- or nanoparticular vesicles comprising crosslinked hyaluronic acid, compositions comprising the same and method for their use in skin care
WO2018122344A1 (en) 2016-12-29 2018-07-05 Nestlé Skin Health Sa Composition comprising a crosslinked hyaluronic acid (ha) in combination with a low-molecular ha and/or an agent stimulating endogenous ha synthesis
EP3600441A1 (en) 2017-03-22 2020-02-05 Genentech, Inc. Hydrogel cross-linked hyaluronic acid prodrug compositions and methods
WO2019073364A1 (en) * 2017-10-12 2019-04-18 Solyplus Berlin Gmbh CROSSLINKING BIOPOLYMERS IN A SEMI-SOLID STATE
JP2022527503A (ja) * 2019-03-24 2022-06-02 アラーガン ファーマシューティカルズ インターナショナル リミテッド 複数の形態のヒアルロン酸を含む注射可能で均質なゲルおよびその製造方法
WO2020234167A1 (en) * 2019-05-17 2020-11-26 ETH Zürich Printable hydrogel, method for generating a printable hydrogel, lyophilizate, printed product and 3d printing method
CN112147029A (zh) * 2019-06-28 2020-12-29 杭州协合医疗用品有限公司 一种交联透明质酸钠凝胶溶胀度的测定方法
US20220298310A1 (en) * 2019-09-27 2022-09-22 Lg Chem, Ltd. A method of preparing polymeric microparticles, polymeric microparticles, medical composition, cosmetic composition, medical articles and cosmetic articles using the same
KR102173790B1 (ko) * 2020-02-26 2020-11-03 (주) 제이피케어즈 가교 히알루론산을 이용한 약물 전달 조성물 및 이의 제조방법
EP4171671A4 (en) * 2020-06-24 2024-07-24 Anika Therapeutics Inc MEDICAL COMPOSITE TEXTILE WITH NON-RESORBABLE FIBERS AND BIORESORBABLE HYALURONATE-BASED FIBERS
KR102527095B1 (ko) 2020-12-18 2023-04-28 충남대학교산학협력단 가교 처리된 히알루론산 조성물의 가교율 측정방법
CN113045779B (zh) * 2021-03-22 2022-09-02 华熙生物科技股份有限公司 一种交联透明质酸凝胶粗品及其制备方法
WO2023064618A1 (en) * 2021-10-15 2023-04-20 Prohibix Llc Crosslinked hyaluronic acid precipitates
CN114404355B (zh) * 2021-12-28 2024-05-24 常州药物研究所有限公司 透明质酸钠凝胶及其制备方法、应用
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Also Published As

Publication number Publication date
EP3013865A1 (en) 2016-05-04
MX2015017526A (es) 2016-08-05
KR102048395B1 (ko) 2019-11-25
RU2640865C2 (ru) 2018-01-12
JP2016524016A (ja) 2016-08-12
EP3617236B1 (en) 2024-07-31
JP6434003B2 (ja) 2018-12-05
US20180362670A1 (en) 2018-12-20
US20160145357A1 (en) 2016-05-26
US11702484B2 (en) 2023-07-18
US20200247913A1 (en) 2020-08-06
WO2014206500A1 (en) 2014-12-31
CN109734825A (zh) 2019-05-10
RU2016101734A (ru) 2017-08-02
US20210214468A1 (en) 2021-07-15
CN109734825B (zh) 2022-01-28
US10077321B2 (en) 2018-09-18
AU2013396752B2 (en) 2018-11-08
EP3617236A1 (en) 2020-03-04
CN105473622B (zh) 2019-01-29
CA2916119A1 (en) 2014-12-31
KR20160027095A (ko) 2016-03-09
AU2013396752A1 (en) 2016-02-18
CN105473622A (zh) 2016-04-06
EP3013865B1 (en) 2019-10-23
MX369409B (es) 2019-11-07
HK1224314A1 (zh) 2017-08-18
US10982016B2 (en) 2021-04-20

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