BR112015030140A2 - forma de dosagem farmacêutica sólida para liberação de pelo menos um ingrediente farmacêutico ativo na cavidade oral - Google Patents

forma de dosagem farmacêutica sólida para liberação de pelo menos um ingrediente farmacêutico ativo na cavidade oral

Info

Publication number
BR112015030140A2
BR112015030140A2 BR112015030140A BR112015030140A BR112015030140A2 BR 112015030140 A2 BR112015030140 A2 BR 112015030140A2 BR 112015030140 A BR112015030140 A BR 112015030140A BR 112015030140 A BR112015030140 A BR 112015030140A BR 112015030140 A2 BR112015030140 A2 BR 112015030140A2
Authority
BR
Brazil
Prior art keywords
dosage form
releasing
oral cavity
pharmaceutical dosage
solid pharmaceutical
Prior art date
Application number
BR112015030140A
Other languages
English (en)
Inventor
Hugerth Andreas
Nicklasson Fredrik
Lindell Katarina
Thyresson Kristina
Original Assignee
Mcneil Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneil Ab filed Critical Mcneil Ab
Publication of BR112015030140A2 publication Critical patent/BR112015030140A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/223—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of alpha-aminoacids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)

Abstract

resumo patente de invenção "forma de dosagem farmacêutica sólida para liberação de pelo menos um ingrediente farmacêutico ativo na cavidade oral". trata-se de forma de dosagem farmacêutica sólida para a liberação de pelo menos um ingrediente farmacêutico ativo (api, em inglês) na cavidade oral compreendendo um núcleo revestido por pelo menos um revestimento de filme. o núcleo compreende pelo menos um api. uma ou mais sensações organolepticamente perturbadoras induzidas por um ou vários apis e/ou componentes inativos da forma de dosagem farmacêutica sólida é/são reduzida(s) pelos constituintes do dito revestimento de filme. os ditos constituintes compreendem pelo menos um polímero formador de filme e pelo menos um agente flavorizante ou pelo menos um adoçante.
BR112015030140A 2013-06-03 2014-06-02 forma de dosagem farmacêutica sólida para liberação de pelo menos um ingrediente farmacêutico ativo na cavidade oral BR112015030140A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE1300404 2013-06-03
PCT/SE2014/050670 WO2014196916A1 (en) 2013-06-03 2014-06-02 Solid pharmaceutical dosage form for release of at least one active pharmaceutical ingredient in the oral cavity

Publications (1)

Publication Number Publication Date
BR112015030140A2 true BR112015030140A2 (pt) 2017-07-25

Family

ID=52008428

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015030140A BR112015030140A2 (pt) 2013-06-03 2014-06-02 forma de dosagem farmacêutica sólida para liberação de pelo menos um ingrediente farmacêutico ativo na cavidade oral

Country Status (13)

Country Link
US (2) US20160095818A1 (pt)
EP (1) EP3003285B1 (pt)
CN (1) CN105307645A (pt)
AU (1) AU2014275543B2 (pt)
BR (1) BR112015030140A2 (pt)
CA (1) CA2914379C (pt)
DK (1) DK3003285T3 (pt)
ES (1) ES2908977T3 (pt)
HK (1) HK1218884A1 (pt)
PL (1) PL3003285T3 (pt)
PT (1) PT3003285T (pt)
RU (1) RU2015156033A (pt)
WO (1) WO2014196916A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9993558B2 (en) 2004-10-01 2018-06-12 Ramscor, Inc. Sustained release eye drop formulations
AU2014268434B2 (en) 2013-05-24 2018-11-22 Icon Bioscience, Inc. Use of sustained release dexamethasone in post-cataract surgery inflammation
US9855227B2 (en) 2015-12-18 2018-01-02 The Procter & Gamble Company Quick dissolving diphenhydramine oral dosage form
CN105833278B (zh) * 2016-04-25 2018-05-08 北京嘉安医疗器械科技有限公司 用于治疗口腔干燥和口腔疾病的组合物
CN105919982A (zh) * 2016-06-30 2016-09-07 合肥华方医药科技有限公司 一种消旋卡多曲口腔速溶膜及其制备方法
HUE055173T2 (hu) 2017-02-01 2021-11-29 Johnson & Johnson Consumer Inc Gyógycukorka
EP3634387B1 (en) 2017-05-22 2024-01-17 Johnson & Johnson Consumer Inc. Lozenge dosage form
RU2749902C2 (ru) * 2018-10-31 2021-06-18 Общество С Ограниченной Ответственностью "Валента-Интеллект" Фармацевтическая композиция для лечения инфекционно-воспалительных заболеваний
US11179331B1 (en) 2020-04-21 2021-11-23 Cure Pharmaceutcai Holding Corp Oral soluble film containing sildenafil citrate
CN113413388B (zh) * 2021-06-30 2022-11-15 上海奥全生物医药科技有限公司 含有枸橼酸西地那非的药物组合物、制备方法及其应用
WO2023028179A1 (en) * 2021-08-25 2023-03-02 Get-Grin Inc. Systems and methods for monitoring a tooth whitening regimen

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE8310750U1 (de) 1983-04-12 1984-07-19 Geppert, Helmut, 5162 Niederzier Spannvorrichtung fuer einen ueber einen eine treibwalze antreibenden getriebemotor angetriebenen bandfoerderer
US4678516A (en) * 1984-10-09 1987-07-07 The Dow Chemical Company Sustained release dosage form based on highly plasticized cellulose ether gels
US5002769A (en) * 1987-03-13 1991-03-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compositions for the sustained-release of chlorhexidine
GB8928196D0 (en) * 1989-12-13 1990-02-14 Merrell Dow Pharmaceuticals Li Pharmaceutical lozenges
US5098715A (en) * 1990-12-20 1992-03-24 Burroughs Wellcome Co. Flavored film-coated tablet
US5614207A (en) * 1995-06-30 1997-03-25 Mcneil-Ppc, Inc. Dry mouth lozenge
AU733140B2 (en) * 1998-09-29 2001-05-10 Hitachi Limited A friction stir welding method
US20020119196A1 (en) * 2000-12-21 2002-08-29 Narendra Parikh Texture masked particles containing an active ingredient
US8980334B2 (en) * 2001-02-28 2015-03-17 Axiomedic Ltd. Double-layered absorbable solid compositions for the topical treatment of oral mucosal disorders
US6596313B2 (en) * 2001-08-06 2003-07-22 The Quigley Corporation Nutritional supplement and methods of using it
EP1656117A1 (en) 2003-08-11 2006-05-17 Merck Frosst Canada Ltd. Flavored taste-masked pharmaceutical formulation made using a one-step coating process
GB0330255D0 (en) * 2003-12-31 2004-02-04 Vectura Ltd Multiparticulate formulations for oral delivery
US20070196474A1 (en) * 2004-04-30 2007-08-23 Withiam Michael C Rapidly disintegrating low friability tablets comprising calcium carbonate
US8238554B2 (en) * 2004-07-22 2012-08-07 Sanyo Electric Co., Ltd. Method for transmission/reception of contents usage right information in encrypted form, and device thereof
DE102004041850A1 (de) 2004-08-27 2006-03-02 Basf Ag Verfahren zur Herstellung von C5-Aldehyden und Propen aus einem 1-Buten- und 2-Buten-haltigen C4-Strom
US8323683B2 (en) * 2005-05-18 2012-12-04 Mcneil-Ppc, Inc. Flavoring of drug-containing chewing gums
WO2007046890A1 (en) * 2005-10-14 2007-04-26 Effrx, Inc. Lozenge for treatment of dry mouth and related conditions
NZ572106A (en) * 2006-03-31 2010-12-24 Rubicon Res Private Ltd Directly compressible composite for orally disintegrating tablets
US20080031927A1 (en) * 2006-07-11 2008-02-07 Catani Steven J Solid oral dosage vitamin and mineral compositions
US20100247453A1 (en) * 2006-07-12 2010-09-30 Thomas L. Jones Composition and method of treating a sore throat
WO2009078034A2 (en) * 2007-11-26 2009-06-25 Rubicon Research Private Limited Oral disintegrating tablets of ropinirole hydrochloride
BRPI0820997A2 (pt) * 2007-12-10 2014-12-23 Eurand Inc Comprimidos de desintegração oral compreendendo difenidramina.
WO2009078037A2 (en) * 2007-12-17 2009-06-25 Gland Pharma Limited Novel process for the preparation of iron sucrose complex
US20100028512A1 (en) * 2008-03-28 2010-02-04 The Coca-Cola Company Bio-based polyethylene terephthalate packaging and method of making thereof
WO2010046933A2 (en) 2008-10-22 2010-04-29 Rubicon Research Private Limited Pharmaceutical compositions of taste-masked linezolid
WO2011030351A2 (en) * 2009-09-03 2011-03-17 Rubicon Research Private Limited Taste - masked pharmaceutical compositions
US9012384B2 (en) * 2010-07-30 2015-04-21 Chevron U.S.A. Inc. Method of preparing greases
JP6521564B2 (ja) 2010-12-22 2019-05-29 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ 速崩性の固体被覆剤形
US8715729B2 (en) * 2010-12-22 2014-05-06 Basf Se Rapidly disintegrating, solid coated dosage form
US20120288591A1 (en) * 2011-05-13 2012-11-15 The Hershey Company Film coated confectionery product
EA034288B1 (ru) * 2011-05-13 2020-01-24 Эб Ип Хибритабс Б.В. Система доставки лекарственного средства
US20130177646A1 (en) * 2012-01-05 2013-07-11 Mcneil Ab Solid Nicotine-Comprising Dosage Form with Reduced Organoleptic Disturbance

Also Published As

Publication number Publication date
HK1218884A1 (zh) 2017-03-17
ES2908977T3 (es) 2022-05-04
US20180338924A1 (en) 2018-11-29
PT3003285T (pt) 2022-05-02
RU2015156033A3 (pt) 2018-05-03
EP3003285B1 (en) 2022-02-16
DK3003285T3 (en) 2022-04-04
RU2015156033A (ru) 2017-07-13
EP3003285A4 (en) 2016-11-23
PL3003285T3 (pl) 2022-06-20
EP3003285A1 (en) 2016-04-13
CA2914379C (en) 2021-03-23
CA2914379A1 (en) 2014-12-11
CN105307645A (zh) 2016-02-03
US20160095818A1 (en) 2016-04-07
AU2014275543B2 (en) 2019-09-12
AU2014275543A1 (en) 2015-12-10
WO2014196916A1 (en) 2014-12-11

Similar Documents

Publication Publication Date Title
BR112015030140A2 (pt) forma de dosagem farmacêutica sólida para liberação de pelo menos um ingrediente farmacêutico ativo na cavidade oral
BR112014016624A8 (pt) forma de dosagem sólida compreendendo nicotina com perturbação organoléptica reduzida
BR112018076601A2 (pt) formulação farmacêutica oral, métodos para tratar um paciente, e, uso de uma formulação
BR112018010234A2 (pt) spray formador de película tópica
BR112013031406A2 (pt) forma de dosagem oral comestível em tira ou disco contendo resina de troca iônica para mascarar o sabor
BR112018067586A2 (pt) composição administrável oralmente
BR112013004416A2 (pt) agente terapêutico para enfisema pulmonar
BRPI0915386B8 (pt) Dispositivo para aplicação de um agente ativo através de mucosa
CL2018001686A1 (es) Métodos y composiciones particularmente para el tratamiento del trastorno por déficit de atención (divisional solicitud 201701026)
CL2015002733A1 (es) Composición farmacéutica de clorhidrato de s-cetamina.
BR112015019430A2 (pt) composição farmacêutica formadora de película para curar ferimento e método para a sua preparação
AR094374A1 (es) Composiciones y métodos para el tratamiento de trastornos metabólicos
MX2018001584A (es) Composiciones de solución sólida para aines.
BR112015031417A2 (pt) forma de dosagem farmacêutica, composição farmacêutica, métodos para tratamento de um paciente com necessidade de cisteamina e para preparo de uma forma de dosagem
BR112015017251A2 (pt) composições farmacêuticas compreendendo doadores de nitroxil
BR112014014795A2 (pt) sistema de pélete de multiunidade de liberação imediata
CL2016002560A1 (es) Forma de dosificación farmacéutica sólida oral que comprende siponimod, un agente protector de la humedad y opcionalmente un excipiente farmacéutico; procedimiento de preparación.
MX2018012800A (es) Administracion de metabolitos de berberina.
BR112018068116A2 (pt) película transmucosal para administração de montelucaste
CO6400184A2 (es) Formulaciones galénicas de compuestos orgánicos
BR112015020237A2 (pt) comprimido com revestimento entérico
CO2018009543A2 (es) Composición farmacéutica de liberación prolongada que comprende cisteamina o sal de la misma
AR096223A1 (es) Pastilla de nicotina para administración oral
BR112014029079A2 (pt) composição farmacêutica para administração oral
CO2018002046A2 (es) Nueva composición oral de libreación retardada dual de dexlansoprazol

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07C Technical examination (opinion): republication [chapter 7.3 patent gazette]

Free format text: REFERENTE AO DESPACHO 7.5 NOTIFICADO NA RPI 2530, DE 02/07/2019.

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements
B350 Update of information on the portal [chapter 15.35 patent gazette]