BR112015023672A2 - análogo de insulina, orto-fluoro, sequência de dna codificando a cadeia a de análogo de insulina, sequência de dna codificando a cadeia b de análogo de insulina e uso de um análogo de insulina. - Google Patents
análogo de insulina, orto-fluoro, sequência de dna codificando a cadeia a de análogo de insulina, sequência de dna codificando a cadeia b de análogo de insulina e uso de um análogo de insulina.Info
- Publication number
- BR112015023672A2 BR112015023672A2 BR112015023672A BR112015023672A BR112015023672A2 BR 112015023672 A2 BR112015023672 A2 BR 112015023672A2 BR 112015023672 A BR112015023672 A BR 112015023672A BR 112015023672 A BR112015023672 A BR 112015023672A BR 112015023672 A2 BR112015023672 A2 BR 112015023672A2
- Authority
- BR
- Brazil
- Prior art keywords
- insulin analog
- chain
- sequence encoding
- dna sequence
- insulin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361798165P | 2013-03-15 | 2013-03-15 | |
PCT/US2014/030387 WO2014145593A2 (en) | 2013-03-15 | 2014-03-17 | Site 2 insulin analogues |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112015023672A2 true BR112015023672A2 (pt) | 2017-07-18 |
Family
ID=51538504
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015023672A BR112015023672A2 (pt) | 2013-03-15 | 2014-03-17 | análogo de insulina, orto-fluoro, sequência de dna codificando a cadeia a de análogo de insulina, sequência de dna codificando a cadeia b de análogo de insulina e uso de um análogo de insulina. |
Country Status (10)
Country | Link |
---|---|
US (1) | US20160083448A1 (pt) |
EP (1) | EP2968473A4 (pt) |
JP (1) | JP2016516728A (pt) |
KR (1) | KR20150138251A (pt) |
CN (1) | CN105228643A (pt) |
AU (1) | AU2014232894B2 (pt) |
BR (1) | BR112015023672A2 (pt) |
CA (1) | CA2942524A1 (pt) |
IL (1) | IL241357B (pt) |
WO (1) | WO2014145593A2 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102351111B1 (ko) | 2014-01-13 | 2022-01-14 | 써멀린 다이어비티즈, 엘엘씨 | 초속효성 인슐린 제형 및 약제학적 전달 시스템 |
CN107428814A (zh) * | 2015-01-20 | 2017-12-01 | 卡斯西部储备大学 | 具有选择性信号传导特性和降低的促有丝***性的胰岛素类似物 |
CR20190096A (es) | 2016-07-22 | 2019-09-16 | Walter & Eliza Hall Inst Medical Res | Análogos de insulina |
CN109891237B (zh) * | 2016-10-24 | 2022-08-23 | 诺和诺德股份有限公司 | 胰岛素制剂的生物测定法 |
US11208453B2 (en) * | 2016-11-21 | 2021-12-28 | Case Western Reserve University | Rapid-acting insulin analogues of enhanced stability |
BR112021005366A2 (pt) * | 2018-09-21 | 2021-06-29 | Case Western Reserve University | análogo de insulina de cadeia simples, uso deste e método para reduzir o açúcar no sangue de um paciente |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK158390D0 (da) * | 1990-07-02 | 1990-07-02 | Novo Nordisk As | Nye peptider |
DK10191D0 (da) * | 1991-01-22 | 1991-01-22 | Novo Nordisk As | Hidtil ukendte peptider |
DK33591D0 (pt) * | 1991-02-27 | 1991-02-27 | Novo Nordisk As | |
EP2049149B1 (en) * | 2006-07-31 | 2015-04-15 | Novo Nordisk A/S | Pegylated extended insulins |
ES2554773T3 (es) | 2006-10-04 | 2015-12-23 | Case Western Reserve University | Insulina y análogos de la insulina resistentes a la fibrilación |
WO2009129250A2 (en) * | 2008-04-14 | 2009-10-22 | Case Western Reserve University | Meal-time insulin analogues of enhanced stability |
EP2296692A4 (en) * | 2008-04-22 | 2012-06-06 | Univ Case Western Reserve | INSULIN ANALOGUES SPECIFIC TO ISOFORMS |
CN102171245B (zh) * | 2008-07-31 | 2015-03-25 | 卡斯西部储备大学 | 卤素稳定型胰岛素 |
-
2014
- 2014-03-17 JP JP2016503388A patent/JP2016516728A/ja active Pending
- 2014-03-17 AU AU2014232894A patent/AU2014232894B2/en not_active Ceased
- 2014-03-17 BR BR112015023672A patent/BR112015023672A2/pt not_active Application Discontinuation
- 2014-03-17 EP EP14764949.5A patent/EP2968473A4/en not_active Withdrawn
- 2014-03-17 CA CA2942524A patent/CA2942524A1/en not_active Abandoned
- 2014-03-17 KR KR1020157029605A patent/KR20150138251A/ko not_active Application Discontinuation
- 2014-03-17 US US14/774,109 patent/US20160083448A1/en not_active Abandoned
- 2014-03-17 CN CN201480026485.XA patent/CN105228643A/zh active Pending
- 2014-03-17 WO PCT/US2014/030387 patent/WO2014145593A2/en active Application Filing
-
2015
- 2015-09-09 IL IL241357A patent/IL241357B/en unknown
Also Published As
Publication number | Publication date |
---|---|
IL241357A0 (en) | 2015-11-30 |
US20160083448A1 (en) | 2016-03-24 |
WO2014145593A3 (en) | 2015-01-08 |
WO2014145593A2 (en) | 2014-09-18 |
AU2014232894B2 (en) | 2018-02-08 |
JP2016516728A (ja) | 2016-06-09 |
KR20150138251A (ko) | 2015-12-09 |
CN105228643A (zh) | 2016-01-06 |
AU2014232894A1 (en) | 2015-11-05 |
CA2942524A1 (en) | 2014-09-18 |
EP2968473A4 (en) | 2016-11-23 |
EP2968473A2 (en) | 2016-01-20 |
IL241357B (en) | 2021-08-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CL2018000813A1 (es) | Conjugados de anticuerpo-fármaco de pirrolobenzodiazepina y métodos de uso. | |
DK3218392T3 (da) | Makrocykliske peptider, der er anvendelige som immunmodulatorer | |
BR112016030968A2 (pt) | análogos de pridopidina, preparação e uso destes | |
DK2963056T3 (da) | Insulinanalog og anvendelse deraf | |
BR112016020618A2 (pt) | oligômero antissentido, composição farmacêutica, e, uso de um oligômero antissentido | |
BR112016003229A2 (pt) | Composto, composição farmacêutica, e, uso de um composto ou de uma composição farmacêutica | |
BR112018004976A2 (pt) | Composição, borracha reticulada, e, gaxeta de coletor de admissão. | |
BR112015023672A2 (pt) | análogo de insulina, orto-fluoro, sequência de dna codificando a cadeia a de análogo de insulina, sequência de dna codificando a cadeia b de análogo de insulina e uso de um análogo de insulina. | |
BR112014031412A2 (pt) | método de preparação de uma composição, composição e seu uso, e kit. | |
DK3131497T3 (da) | Instrumenter til anvendelse med implanterbare indkapslingsindretninger | |
DK3155017T3 (da) | Forbedrede lægemidler til insulinresistens | |
DK3178928T3 (da) | Pint-knockout-mus med en præmatur, aldersassocieret fænotype | |
FR3007989B1 (fr) | Autoinjecteur. | |
EP3232486A4 (en) | Ink composition for organic light-emitting element, and organic light-emitting element using same | |
FR3013601B1 (fr) | Autoinjecteur. | |
BR112017000895A2 (pt) | componente de mancal, mancal, uso de um componente de mancal, e uso de um mancal | |
DK3013147T3 (da) | Sammensætninger, der omfatter pesticidprækursorer, samt fremgangsmåder til fremstilling og anvendelse deraf | |
DK3389701T3 (da) | Nucleotidesekvens, der udtrykker et exosomforankrende, protein til anvendelse som vaccine | |
BR112013019030A2 (pt) | válvula de retenção, e, uso de uma válvula de retenção. | |
BR112016021231A2 (pt) | derivados de hexose, preparação e uso destes. | |
FI20165230A (fi) | Katalysaattoriyksikkö ja pakokaasukatalysaattori | |
IS2968B (is) | Skelflettibúnaður með endingargóðum fingraramma-kambkeflum | |
DK3076990T3 (da) | Biologisk aktive insulinderivater | |
CL2016001961A1 (es) | Levadura biológica, procedimiento de obtención y usos | |
BR112015030989A2 (pt) | composição farmacêutica, e, uso de uma composição |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |