BR112015012985B8 - método para preparar uma espuma líquida hemostática farmacêutica, combinação de produto, espuma líquida hemostática farmacêutica transiente, kit para produzir uma espuma líquida hemostática farmacêutica transiente, e, uso de uma preparação farmacêutica - Google Patents
método para preparar uma espuma líquida hemostática farmacêutica, combinação de produto, espuma líquida hemostática farmacêutica transiente, kit para produzir uma espuma líquida hemostática farmacêutica transiente, e, uso de uma preparação farmacêutica Download PDFInfo
- Publication number
- BR112015012985B8 BR112015012985B8 BR112015012985A BR112015012985A BR112015012985B8 BR 112015012985 B8 BR112015012985 B8 BR 112015012985B8 BR 112015012985 A BR112015012985 A BR 112015012985A BR 112015012985 A BR112015012985 A BR 112015012985A BR 112015012985 B8 BR112015012985 B8 BR 112015012985B8
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical
- liquid foam
- transient
- hemostatic liquid
- foam
- Prior art date
Links
- 230000002439 hemostatic effect Effects 0.000 title abstract 10
- 239000008258 liquid foam Substances 0.000 title abstract 8
- 230000001052 transient effect Effects 0.000 title abstract 6
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000006260 foam Substances 0.000 abstract 3
- 102000009027 Albumins Human genes 0.000 abstract 2
- 108010088751 Albumins Proteins 0.000 abstract 2
- 239000004088 foaming agent Substances 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- 102000008946 Fibrinogen Human genes 0.000 abstract 1
- 108010049003 Fibrinogen Proteins 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000015271 coagulation Effects 0.000 abstract 1
- 238000005345 coagulation Methods 0.000 abstract 1
- 229940012952 fibrinogen Drugs 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000001376 precipitating effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0052—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0028—Polypeptides; Proteins; Degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0085—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M35/00—Devices for applying media, e.g. remedies, on the human body
- A61M35/003—Portable hand-held applicators having means for dispensing or spreading integral media
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/04—Materials for stopping bleeding
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Materials Engineering (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
Abstract
1 / 1 resumo âpreparaãão ã base de espuma lãquida hemostãtica farmacãutica, mãtodo para preparar uma espuma lãquida hemostãtica farmacãutica, combinaãão de produto, espuma lãquida hemostãtica farmacãutica transiente, kit para produzir uma espuma lãquida hemostãtica farmacãutica transiente, e, uso de uma preparaãão farmacãuticaâ a invenã§ã£o descreve uma preparaã§ã£o farmacãªutica ã base de espuma lãquida hemostã¡tica compreendendo albumina como agente espumante e uma substã¢ncia de precipitaã§ã£o de fibrinogãªnio e opcionalmente um agente indutor de coagulaã§ã£o, em que albumina como agente espumante estã¡ presente na forma nativa; um mã©todo para a produã§ã£o de uma espuma lãquida hemostã¡tica transiente; a espuma lãquida hemostã¡tica transiente; e um kit para preparar a espuma.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261734544P | 2012-12-07 | 2012-12-07 | |
US61/734,544 | 2012-12-07 | ||
PCT/EP2013/075852 WO2014086996A1 (en) | 2012-12-07 | 2013-12-06 | Hemostatic foam |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112015012985B1 BR112015012985B1 (pt) | 2020-03-17 |
BR112015012985B8 true BR112015012985B8 (pt) | 2020-04-14 |
Family
ID=49725129
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015012985A BR112015012985B8 (pt) | 2012-12-07 | 2013-12-06 | método para preparar uma espuma líquida hemostática farmacêutica, combinação de produto, espuma líquida hemostática farmacêutica transiente, kit para produzir uma espuma líquida hemostática farmacêutica transiente, e, uso de uma preparação farmacêutica |
Country Status (15)
Country | Link |
---|---|
US (2) | US9168325B2 (pt) |
EP (1) | EP2928511B1 (pt) |
JP (1) | JP2016501255A (pt) |
KR (1) | KR102199092B1 (pt) |
CN (1) | CN104902935B (pt) |
AU (1) | AU2013353931B2 (pt) |
BR (1) | BR112015012985B8 (pt) |
CA (1) | CA2893064C (pt) |
ES (1) | ES2804534T3 (pt) |
HK (1) | HK1212928A1 (pt) |
IL (1) | IL238948A0 (pt) |
MX (1) | MX356867B (pt) |
SG (1) | SG11201504347RA (pt) |
WO (1) | WO2014086996A1 (pt) |
ZA (1) | ZA201503973B (pt) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009109194A2 (en) | 2008-02-29 | 2009-09-11 | Ferrosan A/S | Device for promotion of hemostasis and/or wound healing |
ES2877715T3 (es) * | 2011-10-28 | 2021-11-17 | Baxter Int | Composiciones no acuosas para hemostasia ósea, y métodos para su uso y fabricación |
EP2822474B1 (en) | 2012-03-06 | 2018-05-02 | Ferrosan Medical Devices A/S | Pressurized container containing haemostatic paste |
EP2825216B1 (en) | 2012-06-12 | 2015-08-19 | Ferrosan Medical Devices A/S | Dry haemostatic composition |
WO2014086996A1 (en) * | 2012-12-07 | 2014-06-12 | Baxter International Inc. | Hemostatic foam |
US10201690B2 (en) * | 2013-06-19 | 2019-02-12 | Robert Nutter | Wound injector apparatus |
US9724078B2 (en) | 2013-06-21 | 2017-08-08 | Ferrosan Medical Devices A/S | Vacuum expanded dry composition and syringe for retaining same |
JP6489485B2 (ja) | 2013-12-11 | 2019-03-27 | フェロサン メディカル デバイシーズ エイ/エス | 押し出し増強因子を含んでいる乾燥組成物 |
JP6726852B2 (ja) | 2014-10-13 | 2020-07-22 | フェッローサン メディカル ディバイス エー/エス | 止血および創傷治癒に使用するための乾燥組成物 |
CN107206165B (zh) | 2014-12-24 | 2020-10-23 | 弗罗桑医疗设备公司 | 用于保持并混合第一和第二物质的注射器 |
US10283015B2 (en) | 2015-04-08 | 2019-05-07 | Biom'up | Device and method for simulation of surface bleedings |
JP6747651B2 (ja) | 2015-07-03 | 2020-08-26 | フェロサン メディカル デバイシーズ エイ/エス | 保管状態で真空を保持するための、及び2種の成分を混合するためのシリンジ |
MA46239A (fr) | 2016-09-14 | 2019-07-24 | Ethicon Inc | Mousse pharmaceutique stable |
IL247810A0 (en) | 2016-09-14 | 2017-01-31 | Omrix Biopharmaceuticals Ltd | Stable pharmaceutical foam |
US10980913B2 (en) | 2018-03-05 | 2021-04-20 | Ethicon Llc | Sealant foam compositions for lung applications |
KR20210008479A (ko) | 2018-05-09 | 2021-01-22 | 훼로산 메디칼 디바이스 에이/에스 | 지혈 조성물을 제조하는 방법 |
DE102018009781A1 (de) | 2018-12-13 | 2020-06-18 | Valeopharm GmbH | Verschäumbare wässrige Zubereitungen auf natürlicher Biopolymerbasis mit einsatzflexibler Gas(- vor allem Sauerstoffgas)-Speicherzellen-Verteilung |
WO2021014356A1 (en) * | 2019-07-23 | 2021-01-28 | Kci Licensing, Inc. | Foam compositions for wound treatment, systems of delivery, and methods of use |
US11903961B2 (en) | 2020-08-18 | 2024-02-20 | Amrita Vishwa Vidyapeetham | Hemostatic agent and method of production thereof |
US20220241521A1 (en) * | 2021-02-02 | 2022-08-04 | Freedom Corp. | Device for fibrin-biopolymer-forming substance application |
WO2023170680A1 (en) | 2022-03-08 | 2023-09-14 | Equashield Medical Ltd | Fluid transfer station in a robotic pharmaceutical preparation system |
WO2023177392A1 (en) * | 2022-03-15 | 2023-09-21 | Mayo Foundation For Medical Education And Research | Tissue displacement foam |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
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JPS6054122B2 (ja) * | 1977-12-12 | 1985-11-28 | 日新製鋼株式会社 | 準安定オ−ステナイト系ステンレス鋼の冷間圧延方法 |
DE3171072D1 (en) | 1981-06-25 | 1985-07-25 | Stroetmann M Serapharm | Enriched plasma derivative for promoting wound sealing and wound covering |
JP2796558B2 (ja) | 1986-04-01 | 1998-09-10 | セイコーインスツルメンツ株式会社 | 液晶電気光学素子 |
US4892826A (en) * | 1988-10-11 | 1990-01-09 | Abbott Laboratories | Process for the preparation of urokinase derivatives |
US6054122A (en) | 1990-11-27 | 2000-04-25 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
FR2796558B1 (fr) * | 1999-07-21 | 2001-10-19 | Imedex Biomateriaux | Mousse adhesive a usage chirurgical et/ou therapeutique, et procede et kit pour son obtention |
JP5133482B2 (ja) * | 1999-07-21 | 2013-01-30 | イムデ ビオマテリオー | 外科的及び/又は治療的使用のための接着性タンパク質フォーム、並びにその生産のための方法及びキット |
WO2001062312A1 (en) * | 2000-02-25 | 2001-08-30 | Monterey Biomedical, Inc. | Foam-forming wound dressing |
HU227987B1 (hu) * | 2001-01-25 | 2012-07-30 | Nycomed Pharma As | Szilárd fibrinogént és szilárd trombint tartalmazó hordozó |
US20030211137A1 (en) * | 2001-02-21 | 2003-11-13 | David Sierra | Foam-forming wound dressing |
US6703299B2 (en) | 2001-12-21 | 2004-03-09 | Intel Corporation | Underfill process for flip-chip device |
AU2007205932A1 (en) | 2006-01-17 | 2007-07-26 | Baxter Healthcare S.A. | Device, system and method for mixing |
CA2643084C (en) * | 2006-03-01 | 2015-12-29 | Fmc Biopolymer As | Gelled composite comprising pores and gel within the pores, method of manufacture and use thereof |
GB0623607D0 (en) * | 2006-11-27 | 2007-01-03 | Haemostatix Ltd | Tissue adhesive |
US8512740B2 (en) | 2008-03-26 | 2013-08-20 | Baxter International Inc. | Fibrin foam and process for making |
US8753670B2 (en) | 2008-03-26 | 2014-06-17 | Baxter International Inc. | Fibrin foam and process |
WO2009123903A1 (en) | 2008-04-03 | 2009-10-08 | Zymogenetics, Inc. | Hemostatic microspheres |
KR20120125465A (ko) * | 2010-01-08 | 2012-11-15 | 프로피브릭스 비.브이. | 건조 분말 피브린 실란트 |
KR101814841B1 (ko) * | 2010-06-01 | 2018-01-03 | 백스터 인터내셔널 인코포레이티드 | 건조 및 안정한 지혈 조성물의 제조 방법 |
WO2014086996A1 (en) * | 2012-12-07 | 2014-06-12 | Baxter International Inc. | Hemostatic foam |
-
2013
- 2013-12-06 WO PCT/EP2013/075852 patent/WO2014086996A1/en active Application Filing
- 2013-12-06 AU AU2013353931A patent/AU2013353931B2/en not_active Ceased
- 2013-12-06 EP EP13802044.1A patent/EP2928511B1/en active Active
- 2013-12-06 ES ES13802044T patent/ES2804534T3/es active Active
- 2013-12-06 SG SG11201504347RA patent/SG11201504347RA/en unknown
- 2013-12-06 US US14/099,712 patent/US9168325B2/en active Active
- 2013-12-06 US US14/650,278 patent/US10307509B2/en active Active
- 2013-12-06 KR KR1020157017745A patent/KR102199092B1/ko active IP Right Grant
- 2013-12-06 BR BR112015012985A patent/BR112015012985B8/pt not_active IP Right Cessation
- 2013-12-06 MX MX2015007194A patent/MX356867B/es active IP Right Grant
- 2013-12-06 CA CA2893064A patent/CA2893064C/en active Active
- 2013-12-06 JP JP2015546040A patent/JP2016501255A/ja active Pending
- 2013-12-06 CN CN201380063853.3A patent/CN104902935B/zh not_active Expired - Fee Related
-
2015
- 2015-05-21 IL IL238948A patent/IL238948A0/en unknown
- 2015-06-03 ZA ZA2015/03973A patent/ZA201503973B/en unknown
-
2016
- 2016-01-27 HK HK16100890.3A patent/HK1212928A1/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US20150314037A1 (en) | 2015-11-05 |
EP2928511A1 (en) | 2015-10-14 |
KR102199092B1 (ko) | 2021-01-07 |
MX2015007194A (es) | 2016-03-07 |
US9168325B2 (en) | 2015-10-27 |
US20140161738A1 (en) | 2014-06-12 |
CA2893064A1 (en) | 2014-06-12 |
IL238948A0 (en) | 2015-07-30 |
US10307509B2 (en) | 2019-06-04 |
EP2928511B1 (en) | 2020-04-22 |
AU2013353931B2 (en) | 2016-12-08 |
KR20150093198A (ko) | 2015-08-17 |
HK1212928A1 (zh) | 2016-06-24 |
WO2014086996A1 (en) | 2014-06-12 |
ZA201503973B (en) | 2016-04-28 |
CN104902935B (zh) | 2017-11-24 |
BR112015012985B1 (pt) | 2020-03-17 |
CA2893064C (en) | 2021-05-04 |
SG11201504347RA (en) | 2015-07-30 |
MX356867B (es) | 2018-06-18 |
JP2016501255A (ja) | 2016-01-18 |
AU2013353931A1 (en) | 2015-06-11 |
CN104902935A (zh) | 2015-09-09 |
ES2804534T3 (es) | 2021-02-08 |
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B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2752 DE 03-10-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |