BR112015012411A2 - derivado de hidantoína - Google Patents
derivado de hidantoínaInfo
- Publication number
- BR112015012411A2 BR112015012411A2 BR112015012411A BR112015012411A BR112015012411A2 BR 112015012411 A2 BR112015012411 A2 BR 112015012411A2 BR 112015012411 A BR112015012411 A BR 112015012411A BR 112015012411 A BR112015012411 A BR 112015012411A BR 112015012411 A2 BR112015012411 A2 BR 112015012411A2
- Authority
- BR
- Brazil
- Prior art keywords
- hydantoin derivative
- hydantoin
- derivative
- formula
- acceptable salts
- Prior art date
Links
- 150000001469 hydantoins Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- WJRBRSLFGCUECM-UHFFFAOYSA-N hydantoin Chemical class O=C1CNC(=O)N1 WJRBRSLFGCUECM-UHFFFAOYSA-N 0.000 abstract 1
- 229940091173 hydantoin Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Abstract
resumo patente de invenção: "derivado de hidantoína". a presente invenção provê compostos representados pela fórmula (1) abaixo e seus sais farmacologicamente aceitáveis: em que r1, r2, r3, e r4 são como definidos nas reivindicações.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2012269178 | 2012-12-10 | ||
JP2012-269178 | 2012-12-10 | ||
PCT/JP2013/083022 WO2014092061A1 (ja) | 2012-12-10 | 2013-12-10 | ヒダントイン誘導体 |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112015012411A2 true BR112015012411A2 (pt) | 2017-07-11 |
BR112015012411B1 BR112015012411B1 (pt) | 2021-10-05 |
Family
ID=50934349
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015012411-9A BR112015012411B1 (pt) | 2012-12-10 | 2013-12-10 | Derivado de hidantoína, seu uso, composição farmacêutica e agente de mobilização de célulatronco, ou um agente para prevenção ou tratamento de doenças |
Country Status (35)
Country | Link |
---|---|
US (5) | US9428505B2 (pt) |
EP (1) | EP2930176B1 (pt) |
JP (1) | JP5951799B2 (pt) |
KR (1) | KR102168738B1 (pt) |
CN (1) | CN104854106B (pt) |
AU (1) | AU2013358167B2 (pt) |
BR (1) | BR112015012411B1 (pt) |
CA (1) | CA2892621C (pt) |
CL (2) | CL2015001391A1 (pt) |
CR (1) | CR20150272A (pt) |
DK (1) | DK2930176T3 (pt) |
ES (1) | ES2663797T3 (pt) |
HK (1) | HK1209735A1 (pt) |
HR (1) | HRP20180647T1 (pt) |
HU (1) | HUE037530T2 (pt) |
IL (1) | IL238277B (pt) |
LT (1) | LT2930176T (pt) |
MA (1) | MA38250B1 (pt) |
MX (1) | MX2015007309A (pt) |
MY (1) | MY178583A (pt) |
NO (1) | NO2930176T3 (pt) |
NZ (1) | NZ707946A (pt) |
PE (1) | PE20151295A1 (pt) |
PH (1) | PH12015501146B1 (pt) |
PL (1) | PL2930176T3 (pt) |
PT (1) | PT2930176T (pt) |
RS (1) | RS57190B1 (pt) |
RU (1) | RU2678984C2 (pt) |
SA (1) | SA515360528B1 (pt) |
SG (1) | SG11201504204XA (pt) |
SI (1) | SI2930176T1 (pt) |
TW (1) | TWI615394B (pt) |
UA (1) | UA115072C2 (pt) |
WO (1) | WO2014092061A1 (pt) |
ZA (1) | ZA201503597B (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010126030A1 (ja) | 2009-04-28 | 2010-11-04 | 中外製薬株式会社 | スピロイミダゾロン誘導体 |
JP5951799B2 (ja) * | 2012-12-10 | 2016-07-13 | 中外製薬株式会社 | ヒダントイン誘導体 |
CN106572994B (zh) * | 2014-06-09 | 2020-09-18 | 中外制药株式会社 | 含有乙内酰脲衍生物的药物组合物 |
WO2020027011A1 (ja) | 2018-07-30 | 2020-02-06 | 中外製薬株式会社 | ヒダントイン誘導体の固体分散体 |
CN110464002A (zh) * | 2019-09-12 | 2019-11-19 | 西南石油大学 | 一种天然冰粉的制备方法及其应用 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH1135470A (ja) * | 1997-07-23 | 1999-02-09 | Teijin Ltd | ビタミンd3誘導体を含有する副甲状腺ホルモン産生促進剤 |
EP1137640B1 (en) | 1998-12-11 | 2005-09-21 | F. Hoffmann-La Roche Ag | Cyclic hydrazine derivatives as tnf-alpha inhibitors |
US7004593B2 (en) * | 2002-06-06 | 2006-02-28 | Donnelly Corporation | Interior rearview mirror system with compass |
US20050101574A1 (en) * | 2000-08-30 | 2005-05-12 | Seiichi Ishizuka | Parathyroid hormone production inhibitors containing vitamin d3 derivatives |
KR20040004412A (ko) * | 2000-10-26 | 2004-01-13 | 화이자 프로덕츠 인크. | 스피로-피리미딘-2,4,6-트리온 메탈로프로테이나제 억제제 |
SE0100902D0 (sv) | 2001-03-15 | 2001-03-15 | Astrazeneca Ab | Compounds |
AR038658A1 (es) * | 2001-06-15 | 2005-01-26 | Novartis Ag | Derivados de 4-aril-2(1h) quinazolinona y 4-aril-quinazolina 2-sustituidas, un proceso para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la preparacion de un medicamento |
US20070099940A1 (en) * | 2004-02-11 | 2007-05-03 | Spearing Paul K | Pth agonists |
JP2007522215A (ja) * | 2004-02-11 | 2007-08-09 | スミスクライン・ビーチャム・コーポレイション | Pthアゴニスト |
AU2005294448B2 (en) | 2004-10-07 | 2011-07-14 | Merck Sharp & Dohme Corp. | CGRP receptor antagonists |
WO2007135417A1 (en) | 2006-05-19 | 2007-11-29 | James Black Foundation | Benzotriazepinone derivatives |
MX2008016273A (es) | 2006-06-20 | 2009-01-15 | Wyeth Corp | Inhibidores de canal de potasio kv1.5. |
ES2351378T3 (es) | 2007-06-07 | 2011-02-03 | F. Hoffmann-La Roche Ag | Derivados de prolinamida como antagonistas de nk3. |
CL2008003651A1 (es) | 2007-12-10 | 2009-06-19 | Novartis Ag | Compuestos derivados de 3,5-diamino-6-cloropirazinamida sustituida; composicion farmaceutica; combinacion farmaceutica; y uso en el tratamiento de una condición inflamatoria o alergica, en particular una enfermedad inflamatoria u obstructiva de las vias respiratorias. |
US7981904B2 (en) | 2008-03-20 | 2011-07-19 | Takeda Pharmaceutical Company Limited | Acetyl CoA carboxylase inhibitors |
US8513193B2 (en) | 2008-10-13 | 2013-08-20 | University Of Rochester | Protecting and repairing cartilage and musculoskeletal soft tissues |
WO2010126030A1 (ja) | 2009-04-28 | 2010-11-04 | 中外製薬株式会社 | スピロイミダゾロン誘導体 |
JP5951799B2 (ja) * | 2012-12-10 | 2016-07-13 | 中外製薬株式会社 | ヒダントイン誘導体 |
CN106572994B (zh) * | 2014-06-09 | 2020-09-18 | 中外制药株式会社 | 含有乙内酰脲衍生物的药物组合物 |
-
2013
- 2013-12-10 JP JP2014552040A patent/JP5951799B2/ja active Active
- 2013-12-10 NO NO13862318A patent/NO2930176T3/no unknown
- 2013-12-10 MX MX2015007309A patent/MX2015007309A/es active IP Right Grant
- 2013-12-10 AU AU2013358167A patent/AU2013358167B2/en active Active
- 2013-12-10 LT LTEP13862318.6T patent/LT2930176T/lt unknown
- 2013-12-10 ES ES13862318.6T patent/ES2663797T3/es active Active
- 2013-12-10 US US14/426,408 patent/US9428505B2/en active Active
- 2013-12-10 CN CN201380064459.1A patent/CN104854106B/zh active Active
- 2013-12-10 DK DK13862318.6T patent/DK2930176T3/en active
- 2013-12-10 BR BR112015012411-9A patent/BR112015012411B1/pt active IP Right Grant
- 2013-12-10 SG SG11201504204XA patent/SG11201504204XA/en unknown
- 2013-12-10 TW TW102145318A patent/TWI615394B/zh active
- 2013-12-10 NZ NZ70794613A patent/NZ707946A/en unknown
- 2013-12-10 HU HUE13862318A patent/HUE037530T2/hu unknown
- 2013-12-10 MY MYPI2015701868A patent/MY178583A/en unknown
- 2013-12-10 UA UAA201504548A patent/UA115072C2/uk unknown
- 2013-12-10 RU RU2015127624A patent/RU2678984C2/ru active
- 2013-12-10 RS RS20180517A patent/RS57190B1/sr unknown
- 2013-12-10 PL PL13862318T patent/PL2930176T3/pl unknown
- 2013-12-10 EP EP13862318.6A patent/EP2930176B1/en active Active
- 2013-12-10 CA CA2892621A patent/CA2892621C/en active Active
- 2013-12-10 PT PT138623186T patent/PT2930176T/pt unknown
- 2013-12-10 SI SI201331009T patent/SI2930176T1/en unknown
- 2013-12-10 PE PE2015000878A patent/PE20151295A1/es active IP Right Grant
- 2013-12-10 MA MA38250A patent/MA38250B1/fr unknown
- 2013-12-10 WO PCT/JP2013/083022 patent/WO2014092061A1/ja active Application Filing
- 2013-12-10 KR KR1020157017844A patent/KR102168738B1/ko active IP Right Grant
-
2015
- 2015-04-14 IL IL238277A patent/IL238277B/en active IP Right Grant
- 2015-05-21 CR CR20150272A patent/CR20150272A/es unknown
- 2015-05-21 ZA ZA2015/03597A patent/ZA201503597B/en unknown
- 2015-05-22 CL CL2015001391A patent/CL2015001391A1/es unknown
- 2015-05-22 PH PH12015501146A patent/PH12015501146B1/en unknown
- 2015-06-04 SA SA515360528A patent/SA515360528B1/ar unknown
- 2015-10-23 HK HK15110436.4A patent/HK1209735A1/xx unknown
-
2016
- 2016-07-20 US US15/214,729 patent/US20160326175A1/en not_active Abandoned
-
2017
- 2017-01-11 CL CL2017000069A patent/CL2017000069A1/es unknown
- 2017-12-20 US US15/848,267 patent/US20180237436A1/en not_active Abandoned
-
2018
- 2018-04-24 HR HRP20180647TT patent/HRP20180647T1/hr unknown
-
2020
- 2020-02-28 US US16/805,204 patent/US20210024524A1/en not_active Abandoned
-
2021
- 2021-05-25 US US17/330,200 patent/US20220162208A1/en active Pending
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 10/12/2013, OBSERVADAS AS CONDICOES LEGAIS. |