BR112014023642A2 - proteína interferon-lambda4 (ifnl4), moléculas de anticorpo relacionadas, e usos das mesmas - Google Patents
proteína interferon-lambda4 (ifnl4), moléculas de anticorpo relacionadas, e usos das mesmasInfo
- Publication number
- BR112014023642A2 BR112014023642A2 BR112014023642A BR112014023642A BR112014023642A2 BR 112014023642 A2 BR112014023642 A2 BR 112014023642A2 BR 112014023642 A BR112014023642 A BR 112014023642A BR 112014023642 A BR112014023642 A BR 112014023642A BR 112014023642 A2 BR112014023642 A2 BR 112014023642A2
- Authority
- BR
- Brazil
- Prior art keywords
- interferon
- protein
- lambda4
- antibody molecules
- ifnl4
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/249—Interferons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/706—Specific hybridization probes for hepatitis
- C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
resumo patente de invenção: "proteína interferon-lambda4 (ifnl4), moléculas de anticorpo relacionadas, e usos das mesmas". a invenção refere-se à identificação de uma proteína análoga a interferon (ifnl4) e a sua associação genética com a eliminação espontânea de uma infecção por hcv e resposta ao tratamento para infecção por hcv.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261616664P | 2012-03-28 | 2012-03-28 | |
PCT/US2013/031624 WO2013148272A1 (en) | 2012-03-28 | 2013-03-14 | A NOVEL INTERFERON-λ4 (IFNL4) PROTEIN, RELATED NUCLEIC ACID MOLECULES, AND USES THEREOF |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112014023642A2 true BR112014023642A2 (pt) | 2017-07-18 |
Family
ID=47998550
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014023642A BR112014023642A2 (pt) | 2012-03-28 | 2013-03-14 | proteína interferon-lambda4 (ifnl4), moléculas de anticorpo relacionadas, e usos das mesmas |
Country Status (8)
Country | Link |
---|---|
US (3) | US9678074B2 (pt) |
EP (1) | EP2831106B1 (pt) |
JP (1) | JP6120944B2 (pt) |
CN (1) | CN104540849B (pt) |
AU (1) | AU2013240301B2 (pt) |
BR (1) | BR112014023642A2 (pt) |
CA (1) | CA2869899C (pt) |
WO (1) | WO2013148272A1 (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2013240301B2 (en) | 2012-03-28 | 2017-10-05 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | A novel interferon-lambda4 (IFNL4) protein, related nucleic acid molecules, and uses thereof |
CN106222178A (zh) * | 2016-08-08 | 2016-12-14 | 武汉大学 | 一种重组干扰素λ4编码cDNA序列及其制备方法和应用 |
JP6948685B2 (ja) * | 2016-11-04 | 2021-10-13 | 国立大学法人金沢大学 | 抗癌作用増強剤及び癌治療支援方法 |
GB201621728D0 (en) | 2016-12-20 | 2017-02-01 | Ucb Biopharma Sprl | Methods |
CN107893087A (zh) * | 2017-11-07 | 2018-04-10 | 北京康宝利华生物科技有限公司 | 一种重组猪λ3干扰素的制备方法及其应用 |
CA3190062A1 (en) * | 2019-01-17 | 2020-07-23 | University Health Network | Tissue phantoms |
US20230070752A1 (en) * | 2019-08-21 | 2023-03-09 | Korea Advanced Institute Of Science And Technology | Novel interferon lambda variant and method of producing the same |
US20240009292A1 (en) * | 2020-10-01 | 2024-01-11 | The Johns Hopkins University | Bcg based vaccine compositions and methods of use thereof |
CN114920817B (zh) * | 2022-05-12 | 2023-09-05 | 华中农业大学 | 一种猪干扰素λ4重组蛋白及其制备方法和应用 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0648334A4 (en) | 1992-07-02 | 1996-11-20 | Quidel Corp | IMMUNOASSAY USING DYE-COMPLEXED ENZYME CONJUGATES. |
US5424193A (en) | 1993-02-25 | 1995-06-13 | Quidel Corporation | Assays employing dyed microorganism labels |
WO1994029696A1 (en) | 1993-06-09 | 1994-12-22 | Quidel Corporation | Antigen-specific one-step assays |
US5415994A (en) | 1993-08-02 | 1995-05-16 | Quidel Corporation | Lateral flow medical diagnostic assay device with sample extraction means |
US5656502A (en) | 1995-06-07 | 1997-08-12 | Diagnostic Chemicals Limited | Test strip holder and method of use |
US6001658A (en) | 1996-09-13 | 1999-12-14 | Diagnostic Chemicals Limited | Test strip apparatus and method for determining presence of analyte in a fluid sample |
GB9817266D0 (en) | 1998-08-07 | 1998-10-07 | Imperial College | Method |
ATE385517T1 (de) * | 1999-12-08 | 2008-02-15 | Amgen Inc | Interferon ähnliche moleküle, und deren verwendungen |
CA2735439A1 (en) * | 2008-08-28 | 2010-03-04 | Vertex Pharmaceuticals Incorporated | Analysis of hcv genotypes |
US8535887B2 (en) | 2009-05-21 | 2013-09-17 | Merck Sharp & Dohme Corp. | Genetic markers associated with interferon-alpha response |
US20100316608A1 (en) | 2009-06-15 | 2010-12-16 | Vijayaprakash Suppiah | Method of Determining A Response To Treatment With Immunomodulatory Composition |
CN102665753A (zh) | 2009-07-31 | 2012-09-12 | 佛多斯大学医学研究中心 | 诊断或预测hcv感染的患者中丙型肝炎后果的方法 |
RU2567806C2 (ru) | 2009-12-22 | 2015-11-10 | ЯНССЕН Ар ЭНД Ди АЙРЛЭНД | Усиление прогностической ценности полиморфизма гена il28b в комбинации с количественной оценкой ip-10 в сыворотке при ответе на пегинторферон и рибавирин по сравнению с каждым из этих биомаркеров в отдельности |
US20140154209A1 (en) | 2011-06-30 | 2014-06-05 | Centre Hospitalier Universitaire Vaudois | Polymorphisms associated with non-response to a hepatitis c treatment or susceptibility to non-spontaneous hepatitis c clearance |
US20140271542A1 (en) | 2011-10-05 | 2014-09-18 | The United States Of America As Represented By The Secretary, Department Of Health And Human Service | Genetic marker for predicting prognosis in patients infected with hepatitis c virus |
AU2013240301B2 (en) | 2012-03-28 | 2017-10-05 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | A novel interferon-lambda4 (IFNL4) protein, related nucleic acid molecules, and uses thereof |
-
2013
- 2013-03-14 AU AU2013240301A patent/AU2013240301B2/en active Active
- 2013-03-14 CA CA2869899A patent/CA2869899C/en active Active
- 2013-03-14 WO PCT/US2013/031624 patent/WO2013148272A1/en active Application Filing
- 2013-03-14 CN CN201380028364.4A patent/CN104540849B/zh active Active
- 2013-03-14 EP EP13712655.3A patent/EP2831106B1/en active Active
- 2013-03-14 JP JP2015503310A patent/JP6120944B2/ja active Active
- 2013-03-14 US US14/388,293 patent/US9678074B2/en active Active
- 2013-03-14 BR BR112014023642A patent/BR112014023642A2/pt not_active Application Discontinuation
-
2017
- 2017-05-17 US US15/597,459 patent/US10962539B2/en active Active
-
2020
- 2020-01-24 US US16/752,105 patent/US20200292546A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN104540849A (zh) | 2015-04-22 |
US9678074B2 (en) | 2017-06-13 |
CA2869899A1 (en) | 2013-10-03 |
WO2013148272A1 (en) | 2013-10-03 |
CA2869899C (en) | 2021-06-22 |
AU2013240301B2 (en) | 2017-10-05 |
US20200292546A1 (en) | 2020-09-17 |
AU2013240301A1 (en) | 2014-11-06 |
US20150050640A1 (en) | 2015-02-19 |
CN104540849B (zh) | 2020-07-28 |
EP2831106A1 (en) | 2015-02-04 |
JP2015514709A (ja) | 2015-05-21 |
US10962539B2 (en) | 2021-03-30 |
EP2831106B1 (en) | 2020-07-15 |
JP6120944B2 (ja) | 2017-04-26 |
US20170254808A1 (en) | 2017-09-07 |
WO2013148272A9 (en) | 2014-09-25 |
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Legal Events
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B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NAO 10196/2001, QUE MODIFICOU A LEI NAO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUAANCIA PRA VIA DA ANVISA. CONSIDERANDO A APROVAA AO DOS TERMOS DO PARECER NAO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NAO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDAANCIAS CABA-VEIS. |
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B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |