BR112013020456A2 - nova composição antifúngica - Google Patents

nova composição antifúngica

Info

Publication number
BR112013020456A2
BR112013020456A2 BR112013020456A BR112013020456A BR112013020456A2 BR 112013020456 A2 BR112013020456 A2 BR 112013020456A2 BR 112013020456 A BR112013020456 A BR 112013020456A BR 112013020456 A BR112013020456 A BR 112013020456A BR 112013020456 A2 BR112013020456 A2 BR 112013020456A2
Authority
BR
Brazil
Prior art keywords
antifungal composition
new antifungal
pharmaceutical composition
present
diol
Prior art date
Application number
BR112013020456A
Other languages
English (en)
Other versions
BR112013020456B1 (pt
Inventor
Åke Lindahl
Original Assignee
Moberg Pharma Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Moberg Pharma Ab filed Critical Moberg Pharma Ab
Publication of BR112013020456A2 publication Critical patent/BR112013020456A2/pt
Publication of BR112013020456B1 publication Critical patent/BR112013020456B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

nova composição antifúngica a presente invenção está correlacionada a uma composição farmacêutica para o tratamento de infecção na unha causada por fungo, compreendendo um composto antifúngico de alilamina presente em uma quantidade de cerca de 10%, um ácido orgânico ou um éster do mesmo, um diol e um agente sequëstrador, e em que a composição farmacológica é substancialmente isenta de água.
BR112013020456A 2011-02-11 2012-02-10 nova composição antifúngica BR112013020456B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE1150107 2011-02-11
PCT/EP2012/052327 WO2012107565A1 (en) 2011-02-11 2012-02-10 Novel antifungal composition

Publications (2)

Publication Number Publication Date
BR112013020456A2 true BR112013020456A2 (pt) 2016-10-18
BR112013020456B1 BR112013020456B1 (pt) 2020-01-21

Family

ID=45581892

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013020456A BR112013020456B1 (pt) 2011-02-11 2012-02-10 nova composição antifúngica

Country Status (25)

Country Link
US (3) US8952070B2 (pt)
EP (1) EP2672962B1 (pt)
JP (1) JP5883886B2 (pt)
KR (1) KR101647545B1 (pt)
CN (2) CN109453150A (pt)
AU (1) AU2012215383B2 (pt)
BR (1) BR112013020456B1 (pt)
CA (1) CA2826741C (pt)
CY (1) CY1116275T1 (pt)
DK (1) DK2672962T3 (pt)
ES (1) ES2535827T3 (pt)
HK (1) HK1190944A1 (pt)
HR (1) HRP20150507T1 (pt)
IL (1) IL227765A (pt)
ME (1) ME02152B (pt)
MX (1) MX335945B (pt)
PL (1) PL2672962T3 (pt)
PT (1) PT2672962E (pt)
RS (1) RS53982B1 (pt)
RU (1) RU2587064C2 (pt)
SG (1) SG192615A1 (pt)
SI (1) SI2672962T1 (pt)
SM (1) SMT201500154B (pt)
WO (1) WO2012107565A1 (pt)
ZA (1) ZA201305891B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012215383B2 (en) 2011-02-11 2016-06-09 Moberg Pharma Ab Novel antifungal composition
WO2014032254A1 (zh) 2012-08-30 2014-03-06 华为终端有限公司 一种控制中央处理器的方法和装置
KR20180070607A (ko) * 2015-10-07 2018-06-26 엑소도스 라이프 사이언시스 엘피 항진균 국소 조성물
US10251858B1 (en) 2016-08-08 2019-04-09 Marlinz Pharma, LLC Composition for treating fungal infections in nails
US10543276B2 (en) 2016-08-08 2020-01-28 Marlinz Pharma, LLC Topical compositions
EP3292758A1 (en) 2016-09-07 2018-03-14 Rottapharm S.p.A. Antimicrobial composition comprising a carboxylic acid and two diols
EP3784204B1 (en) * 2018-04-27 2023-12-13 Unigroup ApS Kit of parts for nail fungus
US11576920B2 (en) 2019-03-18 2023-02-14 The Menopause Method, Inc. Composition and method to aid in hormone replacement therapy
AU2021396584A1 (en) 2020-12-08 2023-07-20 Moberg Pharma Ab Treatment regimen for onchyomycosis using allylamine antifungal compositions

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5525635A (en) 1986-02-04 1996-06-11 Moberg; Sven Pharmaceutical compositions containing propylene glycol and/or polyethylene glycol and urea as active main components and use thereof
DE4337945A1 (de) * 1993-11-06 1995-05-11 Labtec Gmbh Pflaster zur Behandlung von Nagelmykosen
US6165484A (en) 1997-08-26 2000-12-26 Wake Forest University EDTA and other chelators with or without antifungal antimicrobial agents for the prevention and treatment of fungal infections
AUPP146598A0 (en) * 1998-01-21 1998-02-12 Health And Hygiene International Pty Ltd Fruit and vegetable wash
DE19921794A1 (de) * 1999-05-11 2000-11-23 Hexal Ag Neue pharmazeutische Zusammensetzung
US7074392B1 (en) 2000-03-27 2006-07-11 Taro Pharmaceutical Industries Limited Controllled delivery system of antifungal and keratolytic agents for local treatment of fungal infections
JP4803511B2 (ja) * 2000-08-25 2011-10-26 株式会社ポーラファルマ 抗真菌医薬組成物
US8486426B2 (en) * 2002-07-29 2013-07-16 Kimberly-Clark Worldwide, Inc. Methods and compositions for treatment of dermal conditions
MXPA05002065A (es) * 2002-09-05 2005-06-08 Galderma Sa Solucion para aplicacion ungueal.
JP5059408B2 (ja) * 2004-08-05 2012-10-24 久光製薬株式会社 爪用外用剤
US20060078599A1 (en) 2004-10-12 2006-04-13 Mathew Ebmeier Pharmaceutical composition applicable to body tissue
JP4992181B2 (ja) * 2004-12-28 2012-08-08 大正製薬株式会社 外用剤組成物
WO2006103638A2 (en) * 2005-03-31 2006-10-05 Ranbaxy Laboratories Limited Topical pharmaceutical compositions of terbinafine and processes for their preparation
GB0511499D0 (en) * 2005-06-06 2005-07-13 Medpharm Ltd Topical ungual formulations
CN1939539A (zh) * 2005-09-29 2007-04-04 瑞士商拜欧伊果公司 疣、指甲疾病、及指甲保养用之局部配方
AU2006332425A1 (en) * 2006-01-02 2007-07-12 Tlt Medical Ltd. Pharmaceutical composition for the treatment of nail diseases
WO2007106622A2 (en) * 2006-02-03 2007-09-20 Carl Lawyer Fungicidal formulation and method of use
WO2007094999A2 (en) * 2006-02-13 2007-08-23 Stiefel Laboratories, Inc. Ungual antifungal compositions
US20080038219A1 (en) 2006-08-07 2008-02-14 Calgenex Corporation Novel Composition for a Topical Skin Treatment Base and Medicated Applications Thereof
WO2008152444A2 (en) * 2006-11-29 2008-12-18 Foamix Ltd. Foamable waterless compositions with modulating agents
BRPI0807083A2 (pt) * 2007-02-05 2015-05-26 Biophile Corp Ltd Eficácia aumentada de compostos de fármaco de alilamina
US20080261986A1 (en) 2007-03-30 2008-10-23 Friden Phillip M Pharmaceutical formulations for iontophoretic delivery of an anti-fungal drug
WO2009140215A2 (en) 2008-05-11 2009-11-19 Geraghty, Erin Method for treating drug-resistant bacterial and other infections with clioquinol, phanquinone, and related compounds
PE20110642A1 (es) * 2008-07-23 2011-08-31 Tdt Ltd Formulaciones antifungicas topicas a base de terbinafina y compuestos similares a terbinafina y metodos de uso
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FR2942716B1 (fr) * 2009-03-06 2011-04-15 Galderma Res & Dev Methode de solubilisation d'agent antifongique et compositions a haute concentration en agent antifongique applicables sur l'ongle
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CN102770123A (zh) * 2009-12-23 2012-11-07 纽沃研究股份有限公司 用于治疗甲癣的高渗透性特比萘芬制剂
WO2012017371A1 (en) * 2010-08-02 2012-02-09 Sulur Subramaniam Vanangamudi A medicinal fusidic acid cream made using sodium fusidate and incorporating a biopolymer, clobetasole propionate, terbinafine hydrochloride and a process to make it
AU2012215383B2 (en) 2011-02-11 2016-06-09 Moberg Pharma Ab Novel antifungal composition

Also Published As

Publication number Publication date
EP2672962B1 (en) 2015-03-25
SI2672962T1 (sl) 2015-06-30
KR20140025341A (ko) 2014-03-04
CN103384518A (zh) 2013-11-06
RS53982B1 (en) 2015-10-30
AU2012215383A1 (en) 2013-08-29
ME02152B (me) 2015-10-20
PT2672962E (pt) 2015-05-25
CN109453150A (zh) 2019-03-12
DK2672962T3 (en) 2015-04-20
WO2012107565A1 (en) 2012-08-16
IL227765A (en) 2016-09-29
RU2587064C2 (ru) 2016-06-10
JP5883886B2 (ja) 2016-03-15
ES2535827T3 (es) 2015-05-18
IL227765A0 (en) 2013-09-30
RU2013136147A (ru) 2015-03-20
HK1190944A1 (en) 2014-07-18
EP2672962A1 (en) 2013-12-18
MX335945B (es) 2016-01-04
AU2012215383B2 (en) 2016-06-09
MX2013009245A (es) 2013-12-09
KR101647545B1 (ko) 2016-08-10
HRP20150507T1 (hr) 2015-06-19
US20170258914A1 (en) 2017-09-14
CN103384518B (zh) 2018-10-26
ZA201305891B (en) 2015-06-24
SMT201500154B (it) 2015-09-07
US20150250878A1 (en) 2015-09-10
JP2014508146A (ja) 2014-04-03
US9561279B2 (en) 2017-02-07
US8952070B2 (en) 2015-02-10
PL2672962T3 (pl) 2015-08-31
CY1116275T1 (el) 2017-02-08
SG192615A1 (en) 2013-09-30
CA2826741C (en) 2016-03-29
BR112013020456B1 (pt) 2020-01-21
US20140031430A1 (en) 2014-01-30
CA2826741A1 (en) 2012-08-16

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 10/02/2012, OBSERVADAS AS CONDICOES LEGAIS.