BR112013019880A2 - sistemas e métodos para dividir gotículas - Google Patents
sistemas e métodos para dividir gotículasInfo
- Publication number
- BR112013019880A2 BR112013019880A2 BR112013019880A BR112013019880A BR112013019880A2 BR 112013019880 A2 BR112013019880 A2 BR 112013019880A2 BR 112013019880 A BR112013019880 A BR 112013019880A BR 112013019880 A BR112013019880 A BR 112013019880A BR 112013019880 A2 BR112013019880 A2 BR 112013019880A2
- Authority
- BR
- Brazil
- Prior art keywords
- droplets
- droplet
- systems
- cases
- divided
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
- B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0673—Handling of plugs of fluid surrounded by immiscible fluid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/12—Specific details about manufacturing devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
- B01L2300/123—Flexible; Elastomeric
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/0318—Processes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/8593—Systems
- Y10T137/85938—Non-valved flow dividers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
sistemas e métodos para dividir gotículas a presente invenção refere-se em geral a sistemas fluídicos e microfluídicos e, em particular, à criação de gotículas em sistema fluídico. em alguns aspectos, a presente invenção é geralmente direcionada a sistemas e métodos para a divisão de uma gotícula mãe em duas ou mas gotículas, por exemplo, incitando a gotícula mãe para um obstáculo para dividir a gotícula mãe. em alguns casos, a gotícula mãe é dividida em, pelo menos, primeira e segunda gotículas que cada uma se dirige para canais separados. em alguns casos, os canais podem ser construídos e dispostos de tal modo que as velocidades das gotículas da primeira e da segunda gotículas são substancialmente as mesmas que a velocidade da gotícula mãe. em alguns casos, tais gotículas podem ser divididas repetidamente, por exemplo, uma gotícula mãe é dividida em duas gotículas filha, então cada gotícula novamente se divide, e etc., por exemplo, de tal forma que uma gotícula mãe pode, eventualmente, ser dividida em 2^ 2^, 2^ 3^, 2^ 4^, 2^ 5^, 2^ 6^, etc. gotículas filha. em alguns casos, as gotículas filha podem ser substancialmente monodispersas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161440198P | 2011-02-07 | 2011-02-07 | |
PCT/US2012/023961 WO2012109138A1 (en) | 2011-02-07 | 2012-02-06 | Systems and methods for splitting droplets |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112013019880A2 true BR112013019880A2 (pt) | 2016-10-11 |
Family
ID=45774321
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013019880A BR112013019880A2 (pt) | 2011-02-07 | 2012-02-06 | sistemas e métodos para dividir gotículas |
Country Status (7)
Country | Link |
---|---|
US (1) | US20140026968A1 (pt) |
EP (1) | EP2673088A1 (pt) |
JP (2) | JP2014505594A (pt) |
KR (1) | KR20140063507A (pt) |
CN (2) | CN105689030A (pt) |
BR (1) | BR112013019880A2 (pt) |
WO (1) | WO2012109138A1 (pt) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL229042B1 (pl) * | 2011-09-30 | 2018-06-29 | Inst Chemii Fizycznej Polskiej Akademii Nauk | Sposób dzielenia kropel w złączu mikroprzepływowym i układ do dzielenia kropel w złączu mikroprzepływowym |
IN2014DN06644A (pt) | 2012-02-08 | 2015-05-22 | Harvard College | |
DE102012217487A1 (de) * | 2012-09-26 | 2014-04-17 | Agilent Technologies, Inc. - A Delaware Corporation - | Fluidschnittstelle zwischen Fluidleitungen unterschiedlicher Querschnitte |
US20160008778A1 (en) * | 2013-03-06 | 2016-01-14 | President And Fellows Of Harvard College | Devices and methods for forming relatively monodisperse droplets |
CN103285947A (zh) * | 2013-05-27 | 2013-09-11 | 苏州扬清芯片科技有限公司 | 一种液滴微流控芯片及其操控方法 |
CN103285946A (zh) * | 2013-05-27 | 2013-09-11 | 苏州扬清芯片科技有限公司 | 一种生物芯片及其操控方法 |
WO2015112985A1 (en) * | 2014-01-24 | 2015-07-30 | The Johns Hopkins University | System and device for high throughput generation of combinatorial droplets and methods of use |
CN105478177A (zh) * | 2014-09-18 | 2016-04-13 | 苏州贝和医疗科技有限公司 | 一种用于数字pcr的液滴生成装置及方法 |
US10178027B2 (en) * | 2016-01-27 | 2019-01-08 | Oracle International Corporation | System and method for supporting inter subnet partitions in a high performance computing environment |
US10171353B2 (en) * | 2016-03-04 | 2019-01-01 | Oracle International Corporation | System and method for supporting dual-port virtual router in a high performance computing environment |
CN109311010B (zh) * | 2016-04-15 | 2022-05-17 | 哈佛学院院长及董事 | 用于收集液滴或其他实体的***和方法 |
US10143129B2 (en) * | 2017-02-27 | 2018-12-04 | Cnh Industrial Canada, Ltd. | Flow splitter for distributing agricultural products and related system |
US10408852B2 (en) | 2017-04-26 | 2019-09-10 | Lawrence Livermore National Security, Llc | Automated control of microfluidic devices based on machine learning |
CN107323090B (zh) * | 2017-07-27 | 2019-01-18 | 京东方科技集团股份有限公司 | 一种打印喷头、打印设备及打印方法 |
CN107754960B (zh) * | 2017-10-26 | 2019-09-03 | 北京工业大学 | 基于附加流量实现双乳液滴非对称***的微流控芯片 |
DE102018203047A1 (de) * | 2018-03-01 | 2019-09-05 | Robert Bosch Gmbh | Mikrofluidische Vorrichtung |
US11465148B2 (en) | 2018-04-16 | 2022-10-11 | Pattern Bioscience, Inc. | Methods and apparatus for forming 2-dimensional drop arrays |
CN108956558B (zh) * | 2018-05-24 | 2023-09-15 | 深圳市帝迈生物技术有限公司 | 一种微流控芯片和免疫荧光分析仪 |
US11703427B2 (en) * | 2018-06-25 | 2023-07-18 | 10X Genomics, Inc. | Methods and systems for cell and bead processing |
US10486155B1 (en) * | 2018-10-22 | 2019-11-26 | Klaris Corporation | Vacuum-loaded, droplet-generating microfluidic chips and related methods |
CN109289951B (zh) * | 2018-10-29 | 2021-01-05 | 深圳先进技术研究院 | 液滴***微流控芯片及应用 |
CN111821927B (zh) * | 2019-04-17 | 2021-12-07 | 北京大学 | 一种制备微/纳结构材料的方法及装置 |
CN112108192B (zh) * | 2019-06-19 | 2022-03-22 | 中国科学院大连化学物理研究所 | 一种微流控芯片及其应用 |
EP3763438A1 (en) * | 2019-07-12 | 2021-01-13 | Curiosity Diagnostics sp. z o.o | Microfluidic chip, production process and uses |
CN110449195A (zh) * | 2019-09-05 | 2019-11-15 | 北京工业大学 | 一种提高液滴在不对称通道***均匀度的装置 |
CN110643488A (zh) * | 2019-09-27 | 2020-01-03 | 晶准生物医学(深圳)有限公司 | 微流控液滴操纵分割装置及其操纵分割方法 |
WO2021168768A1 (zh) * | 2020-02-28 | 2021-09-02 | 京东方科技集团股份有限公司 | 一种微流控芯片和微流控*** |
CN111537398B (zh) * | 2020-05-29 | 2021-10-15 | 河南农业大学 | 一种控制液滴撞击形态、接触时间及液滴可控***的方法 |
EP4180123A1 (en) * | 2021-11-12 | 2023-05-17 | Ecole Polytechnique Fédérale de Lausanne (EPFL) EPFL-TTO | Microfluidic device for sample encapsulation and method for operation thereof |
CN114534811A (zh) * | 2022-02-28 | 2022-05-27 | 上海天马微电子有限公司 | 微流控装置及其制作方法 |
CN115254217B (zh) * | 2022-07-27 | 2023-12-01 | 领航基因科技(杭州)有限公司 | 液滴制备装置及方法 |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2422804A (en) | 1946-01-26 | 1947-06-24 | Walter H Schroeder | Kite |
US5862808A (en) | 1997-08-26 | 1999-01-26 | Cigar Savor Enterprises Llc | Cigar punch |
WO2001088525A1 (en) * | 2000-05-12 | 2001-11-22 | University Of Cincinnati | Structurally programmable microfluidic systems |
US7901939B2 (en) * | 2002-05-09 | 2011-03-08 | University Of Chicago | Method for performing crystallization and reactions in pressure-driven fluid plugs |
JP2006507921A (ja) * | 2002-06-28 | 2006-03-09 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 流体分散のための方法および装置 |
US20060078893A1 (en) * | 2004-10-12 | 2006-04-13 | Medical Research Council | Compartmentalised combinatorial chemistry by microfluidic control |
JP2006523142A (ja) | 2003-04-10 | 2006-10-12 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 流体種の形成および制御 |
WO2004103565A2 (de) * | 2003-05-19 | 2004-12-02 | Hans-Knöll-Institut für Naturstoff-Forschung e.V. | Vorrichtung und verfahren zur strukturierung von flüssigkeiten und zum zudosieren von reaktionsflüssigkeiten zu in separationsmedium eingebetteten flüssigkeitskompartimenten |
EP2662135A3 (en) * | 2003-08-27 | 2013-12-25 | President and Fellows of Harvard College | Method for mixing droplets in a microchannel |
US20050221339A1 (en) * | 2004-03-31 | 2005-10-06 | Medical Research Council Harvard University | Compartmentalised screening by microfluidic control |
US7655470B2 (en) * | 2004-10-29 | 2010-02-02 | University Of Chicago | Method for manipulating a plurality of plugs and performing reactions therein in microfluidic systems |
US7968287B2 (en) * | 2004-10-08 | 2011-06-28 | Medical Research Council Harvard University | In vitro evolution in microfluidic systems |
AU2006220816A1 (en) | 2005-03-04 | 2006-09-14 | President And Fellows Of Harvard College | Method and apparatus for forming multiple emulsions |
FR2890578B3 (fr) * | 2005-09-09 | 2007-11-30 | Rhodia Chimie Sa | Dispositif d'ecoulement microfluidique permettant de determiner des parametres d'une transformation physique et/ ou chimique, et son utilisation |
US7915030B2 (en) * | 2005-09-01 | 2011-03-29 | Canon U.S. Life Sciences, Inc. | Method and molecular diagnostic device for detection, analysis and identification of genomic DNA |
TWI296711B (en) * | 2005-10-11 | 2008-05-11 | Ind Tech Res Inst | Biochip with microchannels |
ATE416508T1 (de) | 2005-10-24 | 2008-12-15 | Conergy Ag | Wechselrichter |
EP1959029A4 (en) | 2005-12-06 | 2013-07-17 | Ebara Udylite Kk | Palladium complex and catalyst-dispersing treatment solution therewith |
US7811603B2 (en) * | 2006-05-09 | 2010-10-12 | The Regents Of The University Of California | Microfluidic device for forming monodisperse lipoplexes |
EP2021113A2 (en) * | 2006-05-11 | 2009-02-11 | Raindance Technologies, Inc. | Microfluidic devices |
WO2008063135A1 (en) * | 2006-11-24 | 2008-05-29 | Agency For Science, Technology And Research | Apparatus for processing a sample in a liquid droplet and method of using the same |
CN102014871A (zh) | 2007-03-28 | 2011-04-13 | 哈佛大学 | 乳液及其形成技术 |
US8883291B2 (en) | 2007-08-07 | 2014-11-11 | President And Fellows Of Harvard College | Metal oxide coating on surfaces |
EP2271581A4 (en) | 2008-03-28 | 2014-09-03 | Harvard College | SURFACES COMPRISING MICROFLUIDIC CHANNELS AND HAVING CONTROLLED OILING PROPERTIES |
EP2286125B1 (en) | 2008-05-16 | 2015-07-08 | President and Fellows of Harvard College | Valves and other flow control in fluidic systems including microfluidic systems |
WO2009152363A2 (en) | 2008-06-11 | 2009-12-17 | David Stansberry | Universal variable transmission line hanger |
JP5553428B2 (ja) * | 2008-08-27 | 2014-07-16 | Nsマテリアルズ株式会社 | ペプチドポリマーの製造方法 |
US20120121480A1 (en) * | 2008-10-08 | 2012-05-17 | Universite De Strasbourg | Microfluidic devices for reliable on-chip incubation of droplets in delay lines |
WO2010104604A1 (en) | 2009-03-13 | 2010-09-16 | President And Fellows Of Harvard College | Method for the controlled creation of emulsions, including multiple emulsions |
US9625454B2 (en) * | 2009-09-04 | 2017-04-18 | The Research Foundation For The State University Of New York | Rapid and continuous analyte processing in droplet microfluidic devices |
JP4973721B2 (ja) * | 2009-12-07 | 2012-07-11 | 東ソー株式会社 | 微小粒子構造体およびそれを用いた微小粒子の製造方法 |
TWI499552B (zh) * | 2012-12-07 | 2015-09-11 | Univ Nat Cheng Kung | 液滴產生方法及裝置 |
US20140161686A1 (en) * | 2012-12-10 | 2014-06-12 | Advanced Liquid Logic, Inc. | System and method of dispensing liquids in a microfluidic device |
US11141730B2 (en) * | 2013-06-14 | 2021-10-12 | President And Fellows Of Harvard College | Coalescence of droplets |
WO2015031528A1 (en) * | 2013-08-27 | 2015-03-05 | Gnubio, Inc. | Microfluidic devices and methods of their use |
-
2012
- 2012-02-06 JP JP2013552712A patent/JP2014505594A/ja active Pending
- 2012-02-06 KR KR1020137023593A patent/KR20140063507A/ko not_active Application Discontinuation
- 2012-02-06 US US13/979,984 patent/US20140026968A1/en not_active Abandoned
- 2012-02-06 EP EP12706734.6A patent/EP2673088A1/en not_active Withdrawn
- 2012-02-06 WO PCT/US2012/023961 patent/WO2012109138A1/en active Application Filing
- 2012-02-06 CN CN201610085021.7A patent/CN105689030A/zh active Pending
- 2012-02-06 CN CN201280007426.9A patent/CN103347612B/zh not_active Expired - Fee Related
- 2012-02-06 BR BR112013019880A patent/BR112013019880A2/pt not_active IP Right Cessation
-
2016
- 2016-07-28 JP JP2016148580A patent/JP2016224057A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP2673088A1 (en) | 2013-12-18 |
KR20140063507A (ko) | 2014-05-27 |
US20140026968A1 (en) | 2014-01-30 |
JP2016224057A (ja) | 2016-12-28 |
WO2012109138A1 (en) | 2012-08-16 |
CN105689030A (zh) | 2016-06-22 |
CN103347612B (zh) | 2016-03-16 |
CN103347612A (zh) | 2013-10-09 |
JP2014505594A (ja) | 2014-03-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR112013019880A2 (pt) | sistemas e métodos para dividir gotículas | |
BR112017016080A2 (pt) | polinucleotídeo, sistema crispr, dois polinucleotídeos e métodos de modificação de uma molécula, de redução de modificação fora do alvo e de aumento da modificação específica de alvo | |
BR112015031320A2 (pt) | sistema para produção de aditivo de estruturas tridimensionais e método para a mesma | |
BR112014019323A8 (pt) | Formação de gotícula com uso de decomposição de fluido | |
BR112017007305A2 (pt) | estruturas fibrosas com aberturas e métodos para a produção das mesmas | |
BR112015020262A2 (pt) | método para combinação de sinais de voz para formar uma conversação contínua na realização de uma busca por voz | |
BR112017024339A2 (pt) | método para a eluição contínua de um produto a partir de colunas de cromatografia | |
BR102013008854A8 (pt) | sistema de proteção contra gelo, e, aeronave | |
BR112016008281A8 (pt) | Sistema de travamento mecânico para painéis de piso | |
BR112014019144A8 (pt) | Sistema de soldagem virtual, ferramenta de soldagem de imitação e método de uso de uma ferramenta de soldagem de imitação | |
BR112014026898A2 (pt) | método de evitar colisão de aeronave, e drone provido com um sistema para implementar o mencionado método | |
BR112018001920A2 (pt) | método e sistema de controle de veículo | |
BR112013029729A2 (pt) | controle de emulsões, incluindo emulsões múltiplas | |
BR112013002972A2 (pt) | método, bio-óleo, e, sistema para recuperar bio-óleo | |
BR112013030584A2 (pt) | sistema e método para preservar referências em sandboxes | |
BR112017025377A2 (pt) | método e sistema para controlar um sistema de conversor catalítico | |
BR112013022451A2 (pt) | dispositivos de separação da membrana, sistemas e métodos que empregam os mesmos e sistemas e métodos de gerenciamento de dados | |
BR112018011117A2 (pt) | cristalizador de fluxo dirigido por pressão | |
BR112013024178A2 (pt) | dispositivo de ncpap e método para dividir um fluxo de jato de gás em um sistema de ncpap | |
BR112016028310A2 (pt) | elemento estrutural | |
BR112015021116A2 (pt) | elemento fixador de penetração de desviador | |
BR112014026183A2 (pt) | sistema e método para fabricação de goma de mascar | |
BR112012017852A2 (pt) | "sistema isolador de comprimento de onda e método dos mesmos para supervisão de uma rede óptica passiva" | |
CL2019000069A1 (es) | Sistema de sujetador y costillas estabilizadoras. | |
BR112017019750A2 (pt) | processo para preparação de uma forma cristalina de menaquinol, forma cristalina de menaquinol, processo para preparação de uma forma sólida do menaquinol, composição farmacêutica ou nutracêutica e uso da forma cristalina de menaquinol |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: application dismissed [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] |