BR112013014597A2 - método de tratamento da pele com moduladores microrna - Google Patents

método de tratamento da pele com moduladores microrna

Info

Publication number
BR112013014597A2
BR112013014597A2 BR112013014597A BR112013014597A BR112013014597A2 BR 112013014597 A2 BR112013014597 A2 BR 112013014597A2 BR 112013014597 A BR112013014597 A BR 112013014597A BR 112013014597 A BR112013014597 A BR 112013014597A BR 112013014597 A2 BR112013014597 A2 BR 112013014597A2
Authority
BR
Brazil
Prior art keywords
treatment method
skin treatment
microrna modulators
microrna
modulators
Prior art date
Application number
BR112013014597A
Other languages
English (en)
Other versions
BR112013014597B1 (pt
Inventor
John W Lyga
Permanan Raaj Khusial
Uma Santhanam
Original Assignee
Avon Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avon Prod Inc filed Critical Avon Prod Inc
Publication of BR112013014597A2 publication Critical patent/BR112013014597A2/pt
Publication of BR112013014597B1 publication Critical patent/BR112013014597B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/17Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A61K8/466Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/18Antioxidants, e.g. antiradicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782Enzyme inhibitors; Enzyme antagonists
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/148Screening for cosmetic compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/178Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BR112013014597-8A 2010-12-28 2011-11-21 método para melhorar o aspecto estético da pele humana BR112013014597B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/979,695 US8455518B2 (en) 2010-12-28 2010-12-28 Method of treating skin with microRNA modulators
US12/979,695 2010-12-28
PCT/US2011/061656 WO2012091824A1 (en) 2010-12-28 2011-11-21 METHOD OF TREATING SKIN WITH microRNA MODULATORS

Publications (2)

Publication Number Publication Date
BR112013014597A2 true BR112013014597A2 (pt) 2016-09-20
BR112013014597B1 BR112013014597B1 (pt) 2020-06-30

Family

ID=46317882

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013014597-8A BR112013014597B1 (pt) 2010-12-28 2011-11-21 método para melhorar o aspecto estético da pele humana

Country Status (12)

Country Link
US (2) US8455518B2 (pt)
EP (2) EP2658537B1 (pt)
JP (1) JP5918783B2 (pt)
CN (2) CN103249409B (pt)
AR (1) AR084598A1 (pt)
BR (1) BR112013014597B1 (pt)
CA (2) CA2817395C (pt)
HK (2) HK1206591A1 (pt)
MX (2) MX367271B (pt)
PL (1) PL2658537T3 (pt)
TW (1) TWI605833B (pt)
WO (1) WO2012091824A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102959077A (zh) 2010-06-30 2013-03-06 雅芳产品公司 用于刺激magp-1以改善皮肤外观的组合物和方法
US8815265B2 (en) * 2010-06-30 2014-08-26 Avon Products, Inc. Cosmetic use of N-substituted sulfonyloxybenzylamines and related compounds
US8632827B2 (en) 2011-12-13 2014-01-21 Avon Products, Inc Modulation of thymosin beta-4 in skin
JP6120398B2 (ja) * 2012-11-02 2017-04-26 国立大学法人三重大学 水溶性フィブリリン組成物による弾性線維増強法
US9186316B2 (en) 2012-12-11 2015-11-17 Avon Products, Inc. Stephanotis jasminoides extracts and methods of use
TW201422246A (zh) 2012-12-11 2014-06-16 Avon Prod Inc 藉由調節wipi-1改善皮膚老化外觀之方法
WO2014092686A1 (en) * 2012-12-11 2014-06-19 Avon Products, Inc. Stephanotis jasminoides extracts and methods of use
WO2014093053A1 (en) * 2012-12-11 2014-06-19 Avon Products, Inc. Modulation of thymosin beta-4 in skin
US9445981B2 (en) * 2012-12-20 2016-09-20 Avon Products, Inc PLOD-2 stimulators and their use in the treatment of skin
CN110205366B (zh) * 2018-02-28 2022-06-21 伽蓝(集团)股份有限公司 一种皮肤内源性老化靶标的筛选方法及改善皮肤内源性老化的活性物及其筛选方法
CN111041082B (zh) * 2018-10-11 2023-11-07 伽蓝(集团)股份有限公司 一种以皮肤光老化靶标筛选改善皮肤光老化的活性物的方法及改善皮肤光老化的活性物
CN111249466B (zh) * 2020-03-14 2022-04-15 浙江大学医学院附属第一医院 丹参酮ⅡA与miR-29b抑制剂联合在制备治疗肌腱粘连的药物中的应用
WO2023012722A1 (en) * 2021-08-06 2023-02-09 Leadermed Champion Limited miRNA-BASED COMPOSITIONS AND METHODS OF USE THEREOF

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9918023D0 (en) * 1999-07-30 1999-09-29 Unilever Plc Skin care composition
WO2003029459A2 (en) 2001-09-28 2003-04-10 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Micro-rna molecules
UA82835C2 (en) * 2001-12-03 2008-05-26 Reddys Lab Ltd Dr ?-aryl-?-oxysubstituted propionuc acid derivatives and pharmaceutical composition based thereon
EP2295604B1 (en) 2004-02-09 2015-04-08 Thomas Jefferson University Diagnosis and treatment of cancers with microRNA located in or near cancer-associated chromosomal features
WO2006133588A1 (en) * 2005-06-13 2006-12-21 Oncalis Ag ARYL UREA COMPOUNDS AS β-SECRETASE INHIBITORS
JP5192380B2 (ja) * 2005-09-08 2013-05-08 株式會社アモーレパシフィック 皮膚老化防止用皮膚外用剤組成物
CA2694930C (en) * 2007-07-31 2019-11-12 Board Of Regents, The University Of Texas System A micro-rna family that modulates fibrosis and uses thereof
WO2009018492A2 (en) * 2007-07-31 2009-02-05 The Board Of Regents Of The University Of Texas System Micro-rnas that control myosin expression and myofiber identity
EP2491007B1 (en) 2009-10-23 2013-09-25 Boehringer Ingelheim International GmbH Inhibitors of the microsomal prostaglandin E2 synthase-1
US8815265B2 (en) * 2010-06-30 2014-08-26 Avon Products, Inc. Cosmetic use of N-substituted sulfonyloxybenzylamines and related compounds
CN102959077A (zh) * 2010-06-30 2013-03-06 雅芳产品公司 用于刺激magp-1以改善皮肤外观的组合物和方法
EP2659004B1 (en) * 2010-12-30 2017-08-30 Avon Products, Inc. Modulation of dynein in skin

Also Published As

Publication number Publication date
MX345299B (es) 2017-01-24
PL2658537T3 (pl) 2015-08-31
CN103249409A (zh) 2013-08-14
BR112013014597B1 (pt) 2020-06-30
WO2012091824A1 (en) 2012-07-05
TWI605833B (zh) 2017-11-21
JP5918783B2 (ja) 2016-05-18
EP2658537B1 (en) 2015-04-29
HK1187251A1 (zh) 2014-04-04
CA3010395C (en) 2020-12-15
CA3010395A1 (en) 2012-07-05
EP2658537A4 (en) 2014-06-25
US8865740B2 (en) 2014-10-21
MX367271B (es) 2019-08-12
HK1206591A1 (en) 2016-01-15
CA2817395A1 (en) 2012-07-05
CN104622704A (zh) 2015-05-20
US8455518B2 (en) 2013-06-04
EP2987534A1 (en) 2016-02-24
AR084598A1 (es) 2013-05-29
US20120165373A1 (en) 2012-06-28
TW201231078A (en) 2012-08-01
CN103249409B (zh) 2016-07-06
MX2013006059A (es) 2013-07-03
EP2658537A1 (en) 2013-11-06
CN104622704B (zh) 2017-12-22
US20130253053A1 (en) 2013-09-26
EP2987534B1 (en) 2024-07-10
JP2014509307A (ja) 2014-04-17
CA2817395C (en) 2019-03-05

Similar Documents

Publication Publication Date Title
BR112013014597A2 (pt) método de tratamento da pele com moduladores microrna
BR112013002644A2 (pt) método de enxertia de pele e método de tratamento de vitiligo
BR112013002642A2 (pt) método de preparo de um enxerto de pele e método de aplicação de enxerto de pele
EP2621420A4 (en) CORNEAL TREATMENT SYSTEM AND METHOD
HK1185908A1 (en) Polymer treatment method
BR112012002536A2 (pt) rejuvenescimento da pele cosmético
BR112013010000A2 (pt) aparelho de cateter
BRPI0906389A2 (pt) Sistema de terapia de pele
GB201108003D0 (en) Endodontic treatment simulation system
HK1207557A1 (en) Method and system for treating biological tissue
BR112014004192A2 (pt) composição de tratamento de sementes, e, método de tratamento de sementes
BR112014016108A2 (pt) método de tratamento de perda óssea alvelar
IL236021A0 (en) Method and system for treating biological tissue
BR112013011659A2 (pt) métodos de tratamento do câncer
GB201018147D0 (en) Method of treatment
IL220594A0 (en) Treatment method
BR112013022820A2 (pt) método de tratamento
BR112013023142A2 (pt) método de tratamento de cabelos
GB201003920D0 (en) Method of treatment
BR112014013667A2 (pt) composição antienvelhecimento da pele
BR112014010294A2 (pt) composição cosmética e método de tratamento de uma condição de pele
BR112014028878A2 (pt) composição cosmética, método de tratamento cosmético da pele e uso de uma composição cosmética
BR112013034066A2 (pt) método de administração e tratamento
EP2832376A4 (en) METHOD FOR TREATING A BIOLOGICAL TISSUE AND BIOLOGICAL TISSUE
BRPI0910199A2 (pt) método de clareamente da pele

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]

Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI.

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: AS CLASSIFICACOES ANTERIORES ERAM: A61K 31/33 , A61K 31/17 , A61K 31/12

Ipc: A61K 8/46 (2006.01), A61K 8/49 (2006.01), A61Q 19/

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 21/11/2011, OBSERVADAS AS CONDICOES LEGAIS.