BR112013014597A2 - método de tratamento da pele com moduladores microrna - Google Patents
método de tratamento da pele com moduladores micrornaInfo
- Publication number
- BR112013014597A2 BR112013014597A2 BR112013014597A BR112013014597A BR112013014597A2 BR 112013014597 A2 BR112013014597 A2 BR 112013014597A2 BR 112013014597 A BR112013014597 A BR 112013014597A BR 112013014597 A BR112013014597 A BR 112013014597A BR 112013014597 A2 BR112013014597 A2 BR 112013014597A2
- Authority
- BR
- Brazil
- Prior art keywords
- treatment method
- skin treatment
- microrna modulators
- microrna
- modulators
- Prior art date
Links
- 108091070501 miRNA Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/17—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/18—Antioxidants, e.g. antiradicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/148—Screening for cosmetic compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Birds (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/979,695 US8455518B2 (en) | 2010-12-28 | 2010-12-28 | Method of treating skin with microRNA modulators |
US12/979,695 | 2010-12-28 | ||
PCT/US2011/061656 WO2012091824A1 (en) | 2010-12-28 | 2011-11-21 | METHOD OF TREATING SKIN WITH microRNA MODULATORS |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112013014597A2 true BR112013014597A2 (pt) | 2016-09-20 |
BR112013014597B1 BR112013014597B1 (pt) | 2020-06-30 |
Family
ID=46317882
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013014597-8A BR112013014597B1 (pt) | 2010-12-28 | 2011-11-21 | método para melhorar o aspecto estético da pele humana |
Country Status (12)
Country | Link |
---|---|
US (2) | US8455518B2 (pt) |
EP (2) | EP2658537B1 (pt) |
JP (1) | JP5918783B2 (pt) |
CN (2) | CN103249409B (pt) |
AR (1) | AR084598A1 (pt) |
BR (1) | BR112013014597B1 (pt) |
CA (2) | CA2817395C (pt) |
HK (2) | HK1206591A1 (pt) |
MX (2) | MX367271B (pt) |
PL (1) | PL2658537T3 (pt) |
TW (1) | TWI605833B (pt) |
WO (1) | WO2012091824A1 (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102959077A (zh) | 2010-06-30 | 2013-03-06 | 雅芳产品公司 | 用于刺激magp-1以改善皮肤外观的组合物和方法 |
US8815265B2 (en) * | 2010-06-30 | 2014-08-26 | Avon Products, Inc. | Cosmetic use of N-substituted sulfonyloxybenzylamines and related compounds |
US8632827B2 (en) | 2011-12-13 | 2014-01-21 | Avon Products, Inc | Modulation of thymosin beta-4 in skin |
JP6120398B2 (ja) * | 2012-11-02 | 2017-04-26 | 国立大学法人三重大学 | 水溶性フィブリリン組成物による弾性線維増強法 |
US9186316B2 (en) | 2012-12-11 | 2015-11-17 | Avon Products, Inc. | Stephanotis jasminoides extracts and methods of use |
TW201422246A (zh) | 2012-12-11 | 2014-06-16 | Avon Prod Inc | 藉由調節wipi-1改善皮膚老化外觀之方法 |
WO2014092686A1 (en) * | 2012-12-11 | 2014-06-19 | Avon Products, Inc. | Stephanotis jasminoides extracts and methods of use |
WO2014093053A1 (en) * | 2012-12-11 | 2014-06-19 | Avon Products, Inc. | Modulation of thymosin beta-4 in skin |
US9445981B2 (en) * | 2012-12-20 | 2016-09-20 | Avon Products, Inc | PLOD-2 stimulators and their use in the treatment of skin |
CN110205366B (zh) * | 2018-02-28 | 2022-06-21 | 伽蓝(集团)股份有限公司 | 一种皮肤内源性老化靶标的筛选方法及改善皮肤内源性老化的活性物及其筛选方法 |
CN111041082B (zh) * | 2018-10-11 | 2023-11-07 | 伽蓝(集团)股份有限公司 | 一种以皮肤光老化靶标筛选改善皮肤光老化的活性物的方法及改善皮肤光老化的活性物 |
CN111249466B (zh) * | 2020-03-14 | 2022-04-15 | 浙江大学医学院附属第一医院 | 丹参酮ⅡA与miR-29b抑制剂联合在制备治疗肌腱粘连的药物中的应用 |
WO2023012722A1 (en) * | 2021-08-06 | 2023-02-09 | Leadermed Champion Limited | miRNA-BASED COMPOSITIONS AND METHODS OF USE THEREOF |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9918023D0 (en) * | 1999-07-30 | 1999-09-29 | Unilever Plc | Skin care composition |
WO2003029459A2 (en) | 2001-09-28 | 2003-04-10 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Micro-rna molecules |
UA82835C2 (en) * | 2001-12-03 | 2008-05-26 | Reddys Lab Ltd Dr | ?-aryl-?-oxysubstituted propionuc acid derivatives and pharmaceutical composition based thereon |
EP2295604B1 (en) | 2004-02-09 | 2015-04-08 | Thomas Jefferson University | Diagnosis and treatment of cancers with microRNA located in or near cancer-associated chromosomal features |
WO2006133588A1 (en) * | 2005-06-13 | 2006-12-21 | Oncalis Ag | ARYL UREA COMPOUNDS AS β-SECRETASE INHIBITORS |
JP5192380B2 (ja) * | 2005-09-08 | 2013-05-08 | 株式會社アモーレパシフィック | 皮膚老化防止用皮膚外用剤組成物 |
CA2694930C (en) * | 2007-07-31 | 2019-11-12 | Board Of Regents, The University Of Texas System | A micro-rna family that modulates fibrosis and uses thereof |
WO2009018492A2 (en) * | 2007-07-31 | 2009-02-05 | The Board Of Regents Of The University Of Texas System | Micro-rnas that control myosin expression and myofiber identity |
EP2491007B1 (en) | 2009-10-23 | 2013-09-25 | Boehringer Ingelheim International GmbH | Inhibitors of the microsomal prostaglandin E2 synthase-1 |
US8815265B2 (en) * | 2010-06-30 | 2014-08-26 | Avon Products, Inc. | Cosmetic use of N-substituted sulfonyloxybenzylamines and related compounds |
CN102959077A (zh) * | 2010-06-30 | 2013-03-06 | 雅芳产品公司 | 用于刺激magp-1以改善皮肤外观的组合物和方法 |
EP2659004B1 (en) * | 2010-12-30 | 2017-08-30 | Avon Products, Inc. | Modulation of dynein in skin |
-
2010
- 2010-12-28 US US12/979,695 patent/US8455518B2/en active Active
-
2011
- 2011-11-21 EP EP20110853582 patent/EP2658537B1/en active Active
- 2011-11-21 CA CA2817395A patent/CA2817395C/en active Active
- 2011-11-21 MX MX2017000916A patent/MX367271B/es unknown
- 2011-11-21 JP JP2013547479A patent/JP5918783B2/ja active Active
- 2011-11-21 PL PL11853582T patent/PL2658537T3/pl unknown
- 2011-11-21 CN CN201180058494.3A patent/CN103249409B/zh active Active
- 2011-11-21 WO PCT/US2011/061656 patent/WO2012091824A1/en active Application Filing
- 2011-11-21 CA CA3010395A patent/CA3010395C/en active Active
- 2011-11-21 EP EP15156211.3A patent/EP2987534B1/en active Active
- 2011-11-21 BR BR112013014597-8A patent/BR112013014597B1/pt active IP Right Grant
- 2011-11-21 MX MX2013006059A patent/MX345299B/es active IP Right Grant
- 2011-11-21 CN CN201410832216.4A patent/CN104622704B/zh active Active
- 2011-12-07 TW TW100145140A patent/TWI605833B/zh active
- 2011-12-27 AR ARP110104940A patent/AR084598A1/es unknown
-
2013
- 2013-05-30 US US13/905,708 patent/US8865740B2/en active Active
-
2014
- 2014-01-09 HK HK15106220.2A patent/HK1206591A1/xx not_active IP Right Cessation
- 2014-01-09 HK HK14100222.4A patent/HK1187251A1/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
MX345299B (es) | 2017-01-24 |
PL2658537T3 (pl) | 2015-08-31 |
CN103249409A (zh) | 2013-08-14 |
BR112013014597B1 (pt) | 2020-06-30 |
WO2012091824A1 (en) | 2012-07-05 |
TWI605833B (zh) | 2017-11-21 |
JP5918783B2 (ja) | 2016-05-18 |
EP2658537B1 (en) | 2015-04-29 |
HK1187251A1 (zh) | 2014-04-04 |
CA3010395C (en) | 2020-12-15 |
CA3010395A1 (en) | 2012-07-05 |
EP2658537A4 (en) | 2014-06-25 |
US8865740B2 (en) | 2014-10-21 |
MX367271B (es) | 2019-08-12 |
HK1206591A1 (en) | 2016-01-15 |
CA2817395A1 (en) | 2012-07-05 |
CN104622704A (zh) | 2015-05-20 |
US8455518B2 (en) | 2013-06-04 |
EP2987534A1 (en) | 2016-02-24 |
AR084598A1 (es) | 2013-05-29 |
US20120165373A1 (en) | 2012-06-28 |
TW201231078A (en) | 2012-08-01 |
CN103249409B (zh) | 2016-07-06 |
MX2013006059A (es) | 2013-07-03 |
EP2658537A1 (en) | 2013-11-06 |
CN104622704B (zh) | 2017-12-22 |
US20130253053A1 (en) | 2013-09-26 |
EP2987534B1 (en) | 2024-07-10 |
JP2014509307A (ja) | 2014-04-17 |
CA2817395C (en) | 2019-03-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] |
Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI. |
|
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B15K | Others concerning applications: alteration of classification |
Free format text: AS CLASSIFICACOES ANTERIORES ERAM: A61K 31/33 , A61K 31/17 , A61K 31/12 Ipc: A61K 8/46 (2006.01), A61K 8/49 (2006.01), A61Q 19/ |
|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 21/11/2011, OBSERVADAS AS CONDICOES LEGAIS. |