BR112013012175A2 - combination, co-administration, use and method - Google Patents

combination, co-administration, use and method

Info

Publication number
BR112013012175A2
BR112013012175A2 BR112013012175A BR112013012175A BR112013012175A2 BR 112013012175 A2 BR112013012175 A2 BR 112013012175A2 BR 112013012175 A BR112013012175 A BR 112013012175A BR 112013012175 A BR112013012175 A BR 112013012175A BR 112013012175 A2 BR112013012175 A2 BR 112013012175A2
Authority
BR
Brazil
Prior art keywords
administration
combination
Prior art date
Application number
BR112013012175A
Other languages
Portuguese (pt)
Inventor
C Ong Christy
Koeppen Hartmut
P Hoeflich Klaus
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR112013012175A2 publication Critical patent/BR112013012175A2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/105Persulfides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
BR112013012175A 2010-11-17 2011-11-14 combination, co-administration, use and method BR112013012175A2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41467110P 2010-11-17 2010-11-17
US201161523062P 2011-08-12 2011-08-12
PCT/EP2011/070008 WO2012065935A1 (en) 2010-11-17 2011-11-14 Methods of treating tumors

Publications (1)

Publication Number Publication Date
BR112013012175A2 true BR112013012175A2 (en) 2019-09-24

Family

ID=44993549

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013012175A BR112013012175A2 (en) 2010-11-17 2011-11-14 combination, co-administration, use and method

Country Status (9)

Country Link
EP (1) EP2640369A1 (en)
JP (1) JP2013542965A (en)
KR (1) KR20130121122A (en)
CN (1) CN103298461A (en)
BR (1) BR112013012175A2 (en)
CA (1) CA2817133A1 (en)
MX (1) MX2013005507A (en)
RU (1) RU2013126036A (en)
WO (1) WO2012065935A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2775601C (en) 2009-09-28 2017-10-03 Qilu Pharmaceutical Co., Ltd 4-(substituted anilino)-quinazoline derivatives useful as tyrosine kinase inhibitors
CN104640865B (en) 2012-09-19 2018-05-11 诺华股份有限公司 Pyrrolin alkane subbase-pyrimidine as kinase inhibitor
SG11201507477XA (en) * 2013-03-14 2015-10-29 Genentech Inc Combinations of a mek inhibitor compound with an her3/egfr inhibitor compound and methods of use
US11517539B2 (en) 2016-02-15 2022-12-06 University Of Georgia Research Foundation, Inc. IPA-3-loaded liposomes and methods of use thereof
KR102351270B1 (en) * 2016-06-16 2022-01-14 하얼빈 젠바오 파마슈티컬 컴퍼니, 리미티드 Akt inhibitor dihydropyrazoloazepine compounds
US20220218715A1 (en) * 2019-05-22 2022-07-14 Voronoi Co., Ltd. Novel use of pyrrolo-pyridine derivative compound for prevention and/or treatment of cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2593428C (en) 2005-01-10 2012-04-17 Pfizer Inc. Pyrrolopyrazoles, potent kinase inhibitors
EP1869052A1 (en) 2005-04-06 2007-12-26 AstraZeneca AB Substituted heterocycles and their use as chk1, pdk1 and pak inhibitors
WO2007023382A2 (en) 2005-08-25 2007-03-01 Pfizer Inc. Pyrimidine amino pyrazole compounds, potent kinase inhibitors
AP2369A (en) 2005-12-21 2012-02-29 Pfizer Prod Inc Carbonylamino pyrrolopyrazoles, potent kinase inhibitors.
CA2691251A1 (en) * 2007-06-19 2008-12-24 Yoshikazu Ohta Preventive/remedy for cancer
US7998688B2 (en) * 2008-03-07 2011-08-16 OSI Pharmaceuticals, LLC Inhibition of EMT induction in tumor cells by anti-cancer agents
US8674095B2 (en) 2008-12-19 2014-03-18 Afraxis Holdings, Inc. Compounds for treating neuropsychiatric conditions

Also Published As

Publication number Publication date
JP2013542965A (en) 2013-11-28
WO2012065935A1 (en) 2012-05-24
CA2817133A1 (en) 2012-05-24
CN103298461A (en) 2013-09-11
RU2013126036A (en) 2014-12-27
KR20130121122A (en) 2013-11-05
EP2640369A1 (en) 2013-09-25
MX2013005507A (en) 2013-07-17

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.