BR112013004322A2 - moduladores de azadecalin fundidos com piridil-aminas - Google Patents
moduladores de azadecalin fundidos com piridil-aminasInfo
- Publication number
- BR112013004322A2 BR112013004322A2 BR112013004322A BR112013004322A BR112013004322A2 BR 112013004322 A2 BR112013004322 A2 BR 112013004322A2 BR 112013004322 A BR112013004322 A BR 112013004322A BR 112013004322 A BR112013004322 A BR 112013004322A BR 112013004322 A2 BR112013004322 A2 BR 112013004322A2
- Authority
- BR
- Brazil
- Prior art keywords
- modulators
- fused azadecalin
- pyridyl amine
- amine fused
- pyridyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37755810P | 2010-08-27 | 2010-08-27 | |
| PCT/US2011/049408 WO2012027702A1 (en) | 2010-08-27 | 2011-08-26 | Pyridyl-amine fused azadecalin modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112013004322A2 true BR112013004322A2 (pt) | 2016-06-21 |
Family
ID=45723831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013004322A BR112013004322A2 (pt) | 2010-08-27 | 2011-08-26 | moduladores de azadecalin fundidos com piridil-aminas |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8598154B2 (pt) |
| EP (1) | EP2609097A4 (pt) |
| JP (1) | JP2013536250A (pt) |
| KR (1) | KR20130106378A (pt) |
| CN (1) | CN103080108A (pt) |
| AU (1) | AU2011293193A1 (pt) |
| BR (1) | BR112013004322A2 (pt) |
| CA (1) | CA2806900A1 (pt) |
| MX (1) | MX2013002186A (pt) |
| SG (1) | SG187909A1 (pt) |
| WO (1) | WO2012027702A1 (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8829024B2 (en) | 2011-01-07 | 2014-09-09 | Corcept Therapeutics, Inc. | Combination steroid and glucocorticoid receptor antagonist therapy |
| PL3338781T3 (pl) * | 2012-05-25 | 2020-03-31 | Corcept Therapeutics Incorporated | Modulatory receptorów glukokortykoidowych typu azadekaliny skondensowanej z heteroaryloketonem |
| US8859774B2 (en) | 2012-05-25 | 2014-10-14 | Corcept Therapeutics, Inc. | Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators |
| PT3074011T (pt) | 2013-11-25 | 2019-09-17 | Corcept Therapeutics Inc | Moduladores de receptores de glicocorticoides de azadecalina fundidas com octa-hidro |
| AU2016226451B2 (en) * | 2015-03-02 | 2019-12-19 | Corcept Therapeutics, Inc. | Use of glucocorticoid receptor antagonist and somatostatin analogues to treat ACTH-secreting tumors |
| WO2018045339A1 (en) | 2016-09-01 | 2018-03-08 | Composite Materials Technology, Inc. | Nano-scale/nanostructured si coating on valve metal substrate for lib anodes |
| KR20180062617A (ko) | 2016-12-01 | 2018-06-11 | 방현희 | 비상구 유도등이 결합 된 벌레 퇴치기 |
| UA127409C2 (uk) | 2017-03-31 | 2023-08-16 | Корцепт Терап'Ютікс, Інк. | Модулятори глюкокортикоїдного рецептора для лікування раку шийки матки |
| US11234971B2 (en) | 2018-12-19 | 2022-02-01 | Corcept Therapeutics Incorporated | Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent |
| US11389432B2 (en) | 2018-12-19 | 2022-07-19 | Corcept Therapeutics Incorporated | Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent |
| CN113194931B (zh) | 2018-12-19 | 2023-11-10 | 科塞普特治疗公司 | 含有瑞拉可兰、杂芳基-酮稠合的氮杂十氢化萘化合物的药物制剂 |
| CA3131263C (en) | 2019-02-22 | 2024-01-02 | Corcept Therapeutics Incorporated | Therapeutic uses of relacorilant, a heteroaryl-ketone fused azadecalin glucocorticoid receptor modulator |
| CN114929229A (zh) | 2019-12-11 | 2022-08-19 | 科赛普特治疗学股份有限公司 | 用米立可兰治疗抗精神病药导致的体重增加的方法 |
| AU2021296163A1 (en) | 2020-06-22 | 2023-02-02 | Corcept Therapeutics Incorporated | Quaternary indazole glucocorticoid receptor antagonists |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8828669D0 (en) | 1988-12-08 | 1989-01-11 | Lilly Industries Ltd | Organic compounds |
| WO2003015692A2 (en) * | 2001-07-17 | 2003-02-27 | Smithkline Beecham Corporation | Crystallized glucocorticoid receptor ligand binding domain polypeptide and screening methods employing same |
| KR101135885B1 (ko) | 2004-01-09 | 2012-04-16 | 코어셉트 쎄라퓨틱스, 잉크. | 아자데칼린 글루코코르티코이드 수용체 조절제 |
| JP4931794B2 (ja) * | 2004-03-09 | 2012-05-16 | コーセプト セラピューティクス， インコーポレイテッド | 縮合環アザデカリン糖質コルチコイド受容体モジュレーター |
| TW200829578A (en) * | 2006-11-23 | 2008-07-16 | Astrazeneca Ab | Chemical compounds 537 |
| CN101616925B (zh) * | 2007-02-02 | 2012-05-23 | 辉瑞产品公司 | 三环化合物及其作为糖皮质激素受体调节剂的用途 |
| EP2209780B1 (en) * | 2007-11-01 | 2014-01-01 | Bristol-Myers Squibb Company | Nonsteroidal compounds useful as modulators of glucocorticoid receptor ap-1 and/or nf- kappa b activity and use thereof |
| US8304539B2 (en) * | 2008-02-07 | 2012-11-06 | Bristol-Myers Squibb Company | Fused heteroaryl modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof |
-
2011
- 2011-08-26 SG SG2013012489A patent/SG187909A1/en unknown
- 2011-08-26 US US13/218,809 patent/US8598154B2/en active Active
- 2011-08-26 CA CA2806900A patent/CA2806900A1/en not_active Abandoned
- 2011-08-26 BR BR112013004322A patent/BR112013004322A2/pt not_active Application Discontinuation
- 2011-08-26 MX MX2013002186A patent/MX2013002186A/es not_active Application Discontinuation
- 2011-08-26 EP EP11820746.3A patent/EP2609097A4/en not_active Withdrawn
- 2011-08-26 JP JP2013526184A patent/JP2013536250A/ja not_active Withdrawn
- 2011-08-26 WO PCT/US2011/049408 patent/WO2012027702A1/en active Application Filing
- 2011-08-26 CN CN2011800415517A patent/CN103080108A/zh active Pending
- 2011-08-26 KR KR1020137007641A patent/KR20130106378A/ko not_active Application Discontinuation
- 2011-08-26 AU AU2011293193A patent/AU2011293193A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20130106378A (ko) | 2013-09-27 |
| US8598154B2 (en) | 2013-12-03 |
| MX2013002186A (es) | 2013-06-28 |
| WO2012027702A1 (en) | 2012-03-01 |
| AU2011293193A1 (en) | 2013-02-14 |
| EP2609097A4 (en) | 2014-04-16 |
| CA2806900A1 (en) | 2012-03-01 |
| JP2013536250A (ja) | 2013-09-19 |
| CN103080108A (zh) | 2013-05-01 |
| EP2609097A1 (en) | 2013-07-03 |
| SG187909A1 (en) | 2013-03-28 |
| US20120220565A1 (en) | 2012-08-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |