BR112012029225A2 - processo para a preparação de um composto quiral, composto quiral e uso de um composto quiral - Google Patents
processo para a preparação de um composto quiral, composto quiral e uso de um composto quiralInfo
- Publication number
- BR112012029225A2 BR112012029225A2 BR112012029225A BR112012029225A BR112012029225A2 BR 112012029225 A2 BR112012029225 A2 BR 112012029225A2 BR 112012029225 A BR112012029225 A BR 112012029225A BR 112012029225 A BR112012029225 A BR 112012029225A BR 112012029225 A2 BR112012029225 A2 BR 112012029225A2
- Authority
- BR
- Brazil
- Prior art keywords
- chiral compound
- preparation
- chiral
- compound
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 3
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C241/00—Preparation of compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C241/04—Preparation of hydrazides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
- C07C243/26—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C243/28—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of a saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C249/16—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of hydrazones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/72—Hydrazones
- C07C251/74—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C251/76—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C07F7/1872—Preparation; Treatments not provided for in C07F7/20
- C07F7/188—Preparation; Treatments not provided for in C07F7/20 by reactions involving the formation of Si-O linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10163212 | 2010-05-19 | ||
| EP10163212.3 | 2010-05-19 | ||
| PCT/EP2011/058035 WO2011144655A1 (en) | 2010-05-19 | 2011-05-18 | Process for the preparation of chiral hydrazides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112012029225A2 true BR112012029225A2 (pt) | 2016-11-29 |
| BR112012029225B1 BR112012029225B1 (pt) | 2020-10-27 |
Family
ID=42710570
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112012029225-0A BR112012029225B1 (pt) | 2010-05-19 | 2011-05-18 | processo para a preparação de um composto quiral, composto quiral e uso de um composto quiral |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9199919B2 (pt) |
| EP (1) | EP2571847B1 (pt) |
| JP (1) | JP5956980B2 (pt) |
| CN (1) | CN102892750B (pt) |
| AU (1) | AU2011254656B2 (pt) |
| BR (1) | BR112012029225B1 (pt) |
| CA (1) | CA2797999C (pt) |
| MX (1) | MX337804B (pt) |
| RU (1) | RU2588570C2 (pt) |
| WO (1) | WO2011144655A1 (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX342850B (es) | 2010-05-19 | 2016-10-14 | Sandoz Ag | Proceso para la preparacion de triazolonas quirales. |
| EP2571868B1 (en) | 2010-05-19 | 2016-05-04 | Sandoz AG | Preparation of posaconazole intermediates |
| BR112012029228A2 (pt) | 2010-05-19 | 2021-08-03 | Sandoz Ag | processo para a preparação de um sal de cloreto de hidrogênio, sal de cloreto de hidrogênio, sal de cloreto de hidrogênio cristalino, uso de um sal e uso do processo |
| CN103635465A (zh) | 2011-06-16 | 2014-03-12 | 桑多斯股份公司 | 制备手性化合物的方法 |
| EP2789610A1 (en) | 2013-04-10 | 2014-10-15 | Sandoz Ag | Purification of Posaconazole Intermediates |
| CN105622464A (zh) * | 2015-12-21 | 2016-06-01 | 上海同昌生物医药科技有限公司 | 一种手性肼的制备方法 |
| CN105618135B (zh) * | 2016-01-10 | 2018-01-16 | 沧州普瑞东方科技有限公司 | 一种手性cbs催化剂的制备方法 |
| CN111323493A (zh) * | 2018-12-14 | 2020-06-23 | 武汉赛沃医药科技有限公司 | 一种泊沙康唑起始物料对映异构体的检测方法 |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3544983A1 (de) | 1985-12-19 | 1987-06-25 | Hoechst Ag | Antimykotisch wirksamer nagellack |
| IL103558A0 (en) | 1991-10-30 | 1993-03-15 | Schering Corp | Tri-substituted tetrahydrofuran antifungals |
| FR2706456B1 (fr) * | 1993-06-18 | 1996-06-28 | Rhone Poulenc Agrochimie | Dérivés optiquement actifs de 2-imidazoline-5-ones et 2-imidazoline-5-thiones fongicides. |
| US5595872A (en) | 1992-03-06 | 1997-01-21 | Bristol-Myers Squibb Company | Nucleic acids encoding microsomal trigyceride transfer protein |
| US5403937A (en) | 1993-04-30 | 1995-04-04 | Schering Corporation | Process for preparing intermediates for the synthesis of antifungal agents |
| US5349099A (en) | 1993-12-13 | 1994-09-20 | Schering Corporation | Process for preparing intermediates for the synthesis of antifungal agents |
| US5710154A (en) | 1993-12-21 | 1998-01-20 | Schering Corporation | Tetrahydrofuran antifungals |
| US5714490A (en) | 1993-12-21 | 1998-02-03 | Schering Corporation | Tetrahydrofuran antifungals |
| CZ294823B6 (cs) | 1993-12-21 | 2005-03-16 | Schering Corporation | Fungicidní tetrahydrofurany |
| US5693626A (en) | 1993-12-21 | 1997-12-02 | Schering Corporation | Tetrahydrofuran antifungals |
| NZ270418A (en) | 1994-02-07 | 1997-09-22 | Eisai Co Ltd | Polycyclic triazole & imidazole derivatives, antifungal compositions |
| US5486625A (en) | 1994-07-08 | 1996-01-23 | Schering Corporation | Process for the preparation of chiral intermediates useful for the synthesis of antifungal agents |
| US5616777A (en) | 1995-04-19 | 1997-04-01 | Schering Corporation | Chiral hydrazine derivatives |
| US5625064A (en) | 1995-04-19 | 1997-04-29 | Schering Corporation | Process for the preparation of triazolones |
| AR002751A1 (es) | 1995-06-02 | 1998-04-29 | Schering Corp | Antifungicos de tetrahidrofurano, composiciones farmaceuticas que los contienen y el uso de los compuestos para preparar composiciones farmaceuticas utiles para el tratamiento de infecciones fungicas |
| WO1997000255A1 (en) | 1995-06-19 | 1997-01-03 | Schering Corporation | Tetrahydrofuran antifungals |
| KR100456181B1 (ko) | 1995-12-20 | 2004-12-31 | 쉐링 코포레이션 | 항진균제합성용중간체의제조방법 |
| SK85998A3 (en) | 1995-12-20 | 1999-02-11 | Schering Corp | Process for preparation of hydrazides |
| EP0885394B1 (de) | 1996-03-08 | 2000-08-16 | Octapharma AG | Verfahren zur eignungsprüfung von faktor viii-haltigen proteinfraktionen |
| US5834472A (en) | 1996-05-24 | 1998-11-10 | Schering Corporation | Antifungal composition with enhanced bioavailability |
| US5972381A (en) | 1996-06-28 | 1999-10-26 | Schering Corporation | Solid solution of an antifungal agent with enhanced bioavailability |
| ZA989063B (en) | 1997-10-07 | 1999-04-06 | Schering Corp | Crystalline antifungal polymorph |
| US6713481B1 (en) | 1997-10-17 | 2004-03-30 | David R. Andrews | Crystalline antifungal polymorph |
| US6355801B1 (en) | 1999-11-08 | 2002-03-12 | Schering Corporation | Process for preparing N-(4-hydroxyphenyl)-N′-(4′-aminophenyl)-piperazine |
| AU1465301A (en) | 1999-11-08 | 2001-06-06 | Schering Corporation | Process for preparing n-(4-hydroxy-phenyl)-n'-(4'-aminophenyl)-piperazine |
| AU2002257104B2 (en) | 2001-04-03 | 2006-02-09 | Merck Sharp & Dohme Corp. | Antifungal composition with enhanced bioavailability |
| JP4617114B2 (ja) * | 2003-08-25 | 2011-01-19 | 学校法人東京理科大学 | 光学活性α−アミノオキシケトン誘導体及びその製造方法 |
| US20090099364A1 (en) | 2004-02-02 | 2009-04-16 | Pfizer Inc. | Process for preparation of 1-(2s,3s)-2-benzhydryl-n-(5- tert-butyl-2-methoxybenzyl)quinuclidin-3-amine |
| CA2567803A1 (en) | 2004-05-28 | 2005-12-15 | Schering Corporation | Injectable pharmaceutical suspension comprising posaconazole |
| MY142804A (en) | 2004-07-01 | 2011-01-14 | Opko Health Inc | Nk1 antagonists |
| CN1709870B (zh) * | 2005-07-19 | 2011-07-06 | 中国科学院成都生物研究所 | 光学纯n′,n′-二取代脯氨酰肼化合物及其制备方法和应用 |
| BRPI0710156A2 (pt) | 2006-04-20 | 2012-06-05 | Glaxo Group Ltd | composto ou um sal do mesno, composição, combinação, e, uso de um composto. |
| SG170047A1 (en) | 2006-05-30 | 2011-04-29 | Elan Pharma Int Ltd | Nanoparticulate posaconazole formulations |
| CN102702185A (zh) | 2007-04-27 | 2012-10-03 | 卫材R&D管理有限公司 | 杂环取代吡啶衍生物的盐的结晶 |
| CA2703257C (en) | 2007-10-29 | 2013-02-19 | Amgen Inc. | Benzomorpholine derivatives and methods of use |
| WO2009129297A1 (en) | 2008-04-15 | 2009-10-22 | Schering Corporation | Semi-solid oral pharmaceutical compositions |
| WO2009141837A2 (en) | 2008-05-21 | 2009-11-26 | Ind-Swift Laboratories Limited | Process for preparing posaconazole and intermediates thereof |
| EP2130540A1 (en) * | 2008-06-02 | 2009-12-09 | Sandoz AG | Pharmaceutical compositions containing a crystalline form of posaconazole |
| EP2141159A1 (en) | 2008-07-03 | 2010-01-06 | Sandoz AG | A Crystalline form of posaconazole |
| AU2009339445A1 (en) | 2009-02-05 | 2011-08-18 | Targeted Delivery Technologies Limited | Methods of reducing the proliferation and viability of microbial agents |
| BR112012029228A2 (pt) | 2010-05-19 | 2021-08-03 | Sandoz Ag | processo para a preparação de um sal de cloreto de hidrogênio, sal de cloreto de hidrogênio, sal de cloreto de hidrogênio cristalino, uso de um sal e uso do processo |
| EP2571868B1 (en) | 2010-05-19 | 2016-05-04 | Sandoz AG | Preparation of posaconazole intermediates |
| MX342850B (es) | 2010-05-19 | 2016-10-14 | Sandoz Ag | Proceso para la preparacion de triazolonas quirales. |
| WO2013186320A1 (en) | 2012-06-14 | 2013-12-19 | Sandoz Ag | Pharmaceutical composition comprising crystalline posaconazole |
-
2011
- 2011-05-18 AU AU2011254656A patent/AU2011254656B2/en not_active Ceased
- 2011-05-18 MX MX2012013333A patent/MX337804B/es active IP Right Grant
- 2011-05-18 JP JP2013510612A patent/JP5956980B2/ja not_active Expired - Fee Related
- 2011-05-18 CN CN201180024363.3A patent/CN102892750B/zh not_active Expired - Fee Related
- 2011-05-18 CA CA2797999A patent/CA2797999C/en not_active Expired - Fee Related
- 2011-05-18 EP EP11723381.7A patent/EP2571847B1/en not_active Not-in-force
- 2011-05-18 US US13/697,800 patent/US9199919B2/en not_active Expired - Fee Related
- 2011-05-18 RU RU2012154810/04A patent/RU2588570C2/ru active
- 2011-05-18 WO PCT/EP2011/058035 patent/WO2011144655A1/en active Application Filing
- 2011-05-18 BR BR112012029225-0A patent/BR112012029225B1/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2571847B1 (en) | 2016-09-21 |
| US9199919B2 (en) | 2015-12-01 |
| AU2011254656B2 (en) | 2015-04-16 |
| BR112012029225B1 (pt) | 2020-10-27 |
| MX337804B (es) | 2016-03-18 |
| RU2012154810A (ru) | 2014-06-27 |
| JP5956980B2 (ja) | 2016-07-27 |
| CA2797999C (en) | 2019-07-09 |
| WO2011144655A1 (en) | 2011-11-24 |
| MX2012013333A (es) | 2013-02-01 |
| RU2588570C2 (ru) | 2016-07-10 |
| CA2797999A1 (en) | 2011-11-24 |
| CN102892750A (zh) | 2013-01-23 |
| AU2011254656A1 (en) | 2012-12-20 |
| JP2013530946A (ja) | 2013-08-01 |
| US20130203993A1 (en) | 2013-08-08 |
| CN102892750B (zh) | 2016-03-02 |
| EP2571847A1 (en) | 2013-03-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 18/05/2011, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 12A ANUIDADE. |
|
| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2724 DE 21-03-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |