BR112012022442A2 - processo para a preparação de um polimorfo de ranelato de estrôncio - Google Patents

processo para a preparação de um polimorfo de ranelato de estrôncio

Info

Publication number
BR112012022442A2
BR112012022442A2 BR112012022442A BR112012022442A BR112012022442A2 BR 112012022442 A2 BR112012022442 A2 BR 112012022442A2 BR 112012022442 A BR112012022442 A BR 112012022442A BR 112012022442 A BR112012022442 A BR 112012022442A BR 112012022442 A2 BR112012022442 A2 BR 112012022442A2
Authority
BR
Brazil
Prior art keywords
preparation
polymorph
strontium ranelate
ranelate
strontium
Prior art date
Application number
BR112012022442A
Other languages
English (en)
Inventor
Baratella Marco
Original Assignee
Chemelectiva Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemelectiva Srl filed Critical Chemelectiva Srl
Publication of BR112012022442A2 publication Critical patent/BR112012022442A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D333/40—Thiophene-2-carboxylic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

processo para a preparação de um polimorfo de ranelato de estrôncio. um polimorfo de ranelato de estrôncio anidro, um método para a sua preparação, composições farmacêuticas que o contêm e o seu uso como um medicamento são descritos. a invenção também se refere a um novo sal de ranelato, útil como um intermediário na preparação de ranelato de estrôncio.
BR112012022442A 2010-03-05 2011-03-01 processo para a preparação de um polimorfo de ranelato de estrôncio BR112012022442A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI2010A000355A IT1398542B1 (it) 2010-03-05 2010-03-05 Processo per la preparazione di un polimorfo
PCT/EP2011/052980 WO2011107454A1 (en) 2010-03-05 2011-03-01 Process for the preparation of a polymorph of strontium ranelate

Publications (1)

Publication Number Publication Date
BR112012022442A2 true BR112012022442A2 (pt) 2019-09-24

Family

ID=42729414

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012022442A BR112012022442A2 (pt) 2010-03-05 2011-03-01 processo para a preparação de um polimorfo de ranelato de estrôncio

Country Status (5)

Country Link
EP (1) EP2542546A1 (pt)
CN (1) CN102791700A (pt)
BR (1) BR112012022442A2 (pt)
IT (1) IT1398542B1 (pt)
WO (1) WO2011107454A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2641905A1 (en) 2012-03-23 2013-09-25 Urquima S.A. Solid forms of strontium ranelate and processes for their preparation

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2651497B1 (fr) * 1989-09-01 1991-10-25 Adir Nouveaux sels de metaux bivalents de l'acide n, n-di (carboxymethyl)amino-2 cyano-3 carboxymethyl-4 carboxy-5 thiophene, leur procede de preparation et les compositions pharmaceutiques les renfermant.
FR2875807B1 (fr) * 2004-09-30 2006-11-17 Servier Lab Forme cristalline alpha du ranelate de strontium, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
AU2006281157B2 (en) 2005-08-19 2013-03-28 Glenmark Pharmaceuticals Limited Process for the preparation of strontium ranelate
CN100591677C (zh) 2006-01-04 2010-02-24 上海医药工业研究院 雷尼酸锶四水合物的制备方法
CN1839827A (zh) * 2006-01-16 2006-10-04 重庆医药工业研究院有限责任公司 雷尼酸锶咀嚼片及其制备方法
CN100554263C (zh) 2006-07-19 2009-10-28 天津药物研究院 雷奈酸锶七水合物的制备方法
FR2921367B1 (fr) * 2007-09-26 2009-10-30 Servier Lab Nouveau procede de synthese du ranelate de strontium et de ses hydrates
CN102227419A (zh) * 2008-09-29 2011-10-26 拉蒂奥法姆有限责任公司 无水和水合形式的雷奈酸锶
HU228820B1 (en) * 2010-01-14 2013-05-28 Richter Gedeon Nyrt Process for the preparation of distrontium ranelate

Also Published As

Publication number Publication date
CN102791700A (zh) 2012-11-21
IT1398542B1 (it) 2013-03-01
EP2542546A1 (en) 2013-01-09
WO2011107454A1 (en) 2011-09-09
ITMI20100355A1 (it) 2011-09-06

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Legal Events

Date Code Title Description
B08F Application fees: dismissal - article 86 of industrial property law
B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.