BR112012014107B8 - sistema terapêutico transdérmico (tts) e processo de produção de tts - Google Patents

sistema terapêutico transdérmico (tts) e processo de produção de tts

Info

Publication number
BR112012014107B8
BR112012014107B8 BR112012014107A BR112012014107A BR112012014107B8 BR 112012014107 B8 BR112012014107 B8 BR 112012014107B8 BR 112012014107 A BR112012014107 A BR 112012014107A BR 112012014107 A BR112012014107 A BR 112012014107A BR 112012014107 B8 BR112012014107 B8 BR 112012014107B8
Authority
BR
Brazil
Prior art keywords
tts
therapeutic system
transdermal therapeutic
production process
peptide
Prior art date
Application number
BR112012014107A
Other languages
English (en)
Other versions
BR112012014107B1 (pt
BR112012014107A2 (pt
Inventor
Dzekan Horst
Horstmann Michael
Wiedersberg Sandra
Original Assignee
Lts Lohmann Therapie Systeme Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lts Lohmann Therapie Systeme Ag filed Critical Lts Lohmann Therapie Systeme Ag
Publication of BR112012014107A2 publication Critical patent/BR112012014107A2/pt
Publication of BR112012014107B1 publication Critical patent/BR112012014107B1/pt
Publication of BR112012014107B8 publication Critical patent/BR112012014107B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/095—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10—Methods of surface bonding and/or assembly therefor
    • Y10T156/1089—Methods of surface bonding and/or assembly therefor of discrete laminae to single face of additional lamina

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

sistema terapêutico transdérmico para administração de peptídeos. a invenção refere-se a um sistema terapêutico transdérmico (tts), que é apropriado para a administração de um peptídeo através da pele tratada com ablação em um paciente. o tts compreende uma camada posterior e uma camada que contem substância ativa, que contém pelo menos um peptídeo e uma substância de veículo.
BR112012014107A 2009-12-04 2010-12-02 sistema terapêutico transdérmico (tts) e processo de produção de tts BR112012014107B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102009056746A DE102009056746A1 (de) 2009-12-04 2009-12-04 Transdermales therapeutisches System für die Verabreichung von Peptiden
DE102009056746.1 2009-12-04
PCT/EP2010/007322 WO2011066970A2 (de) 2009-12-04 2010-12-02 Transdermales therapeutisches system für die verabreichung von peptiden

Publications (3)

Publication Number Publication Date
BR112012014107A2 BR112012014107A2 (pt) 2016-08-16
BR112012014107B1 BR112012014107B1 (pt) 2021-03-30
BR112012014107B8 true BR112012014107B8 (pt) 2021-05-25

Family

ID=43972209

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012014107A BR112012014107B8 (pt) 2009-12-04 2010-12-02 sistema terapêutico transdérmico (tts) e processo de produção de tts

Country Status (9)

Country Link
US (1) US10772845B2 (pt)
EP (1) EP2506839B1 (pt)
JP (1) JP5845190B2 (pt)
CN (2) CN102639124A (pt)
BR (1) BR112012014107B8 (pt)
CA (1) CA2782741C (pt)
DE (1) DE102009056746A1 (pt)
ES (1) ES2674561T3 (pt)
WO (1) WO2011066970A2 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2710085B1 (en) 2011-05-16 2018-09-26 Avery Dennison Corporation Adhesive containing microparticles
WO2014124232A2 (en) 2013-02-07 2014-08-14 Avery Dennison Corporation Antimicrobial adhesives having improved properties
US11213432B2 (en) 2013-03-15 2022-01-04 Avery Dennison Corporation Transparent cover dressing application system and inclusion of label strip
US11337940B2 (en) 2014-06-05 2022-05-24 Avery Dennison Corporation Articles with active agent concentrated at the substrate contacting surface and related methods
EP3384904A1 (en) * 2017-04-03 2018-10-10 tesa Labtec GmbH Pharmaceutical preparation for dermal administration
DE102017127433A1 (de) * 2017-11-21 2019-05-23 Lts Lohmann Therapie-Systeme Ag TTS auf Basis von klebenden Weichmacher-Polymer-Matrices

Family Cites Families (32)

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US3797494A (en) * 1969-04-01 1974-03-19 Alza Corp Bandage for the administration of drug by controlled metering through microporous materials
US3598122A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US4140115A (en) * 1973-12-03 1979-02-20 Johnson & Johnson Pressure sensitive adhesive compositions for coating articles to be attached to skin
US4834978A (en) * 1984-10-01 1989-05-30 Biotek, Inc. Method of transdermal drug delivery
US4616644A (en) * 1985-06-14 1986-10-14 Johnson & Johnson Products, Inc. Hemostatic adhesive bandage
DE3634016A1 (de) * 1986-04-17 1987-10-29 Lohmann Gmbh & Co Kg Flaechenfoermiges therapeutisches system, verfahren zu seiner herstellung und seine verwendung
US5225473A (en) * 1987-11-25 1993-07-06 Minnesota Mining And Manufacturing Company Pressure-sensitive adhesives
DE3910543A1 (de) * 1989-04-01 1990-10-11 Lohmann Therapie Syst Lts Transdermales therapeutisches system mit erhoehtem wirkstofffluss und verfahren zu seiner herstellung
DE4332093C2 (de) * 1993-09-22 1995-07-13 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit dem Wirkstoff Acetylsalicylsäure und Verfahren zu seiner Herstellung
GB9409281D0 (en) * 1994-05-10 1994-06-29 Svedman Paul Transdermal device
DE19738855C2 (de) * 1997-09-05 2001-01-04 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit haftklebender Reservoirschicht und unidirektional elastischer Rückschicht
FR2776518B1 (fr) * 1998-03-24 2002-11-29 Oreal Patch a matrice adhesive
US6597946B2 (en) * 1998-11-09 2003-07-22 Transpharma Ltd. Electronic card for transdermal drug delivery and analyte extraction
US6383511B1 (en) * 1999-10-25 2002-05-07 Epicept Corporation Local prevention or amelioration of pain from surgically closed wounds
US20030104041A1 (en) * 1999-12-16 2003-06-05 Tsung-Min Hsu Transdermal and topical administration of drugs using basic permeation enhancers
US7537795B2 (en) 2000-10-26 2009-05-26 Alza Corporation Transdermal drug delivery devices having coated microprotrusions
NZ524940A (en) * 2000-11-06 2003-08-29 Samyang Corp A multilayered sandwich transdermal drug delivery system with improved water absorbability and adhesion properties
DE10118282A1 (de) 2001-04-12 2002-12-05 Lohmann Therapie Syst Lts Haftkleber auf Basis von Ethylen-Vinylacetat-Copolymeren und Klebharzen, für medizinische Verwendungszwecke
US6967261B1 (en) * 2001-12-28 2005-11-22 Kimberly-Clark Worldwide Bandage, methods of producing and using same
AU2002361900A1 (en) * 2002-01-02 2003-07-24 Scapa North America Hydrocolloid bandage
AU2003303525A1 (en) * 2002-12-31 2004-07-29 Ultra-Sonic Technologies, L.L.C. Transdermal delivery using encapsulated agent activated by ultrasound and/or heat
WO2005042054A2 (en) * 2003-10-24 2005-05-12 Alza Corporation Pretreatment method and system for enhancing transdermal drug delivery
DE10353629A1 (de) * 2003-11-17 2005-06-16 Lts Lohmann Therapie-Systeme Ag Vorrichtung zur transdermalen Verabreichung von Wirkstoffen
WO2005072669A1 (ja) * 2004-01-30 2005-08-11 Hisamitsu Pharmaceutical Co., Inc. カバー材及びカバー材付き貼付剤
TW200628175A (en) * 2004-10-08 2006-08-16 Noven Pharma Transdermal drug delivert device including an occlusive backing
US7572596B2 (en) * 2004-12-02 2009-08-11 University Of Pittsburgh Of The Commonwealth System Of Higher Education Modulation of the neuroendoctrine system as a therapy for motor neuron disease
US8372806B2 (en) 2005-10-06 2013-02-12 Pantec Biosolutions Ag Transdermal delivery system for treating infertility
WO2007149938A2 (en) * 2006-06-21 2007-12-27 The Salk Institute Biological Studies Methods for promoting hair growth
WO2009005814A2 (en) * 2007-07-03 2009-01-08 Marchitto Kevin S Drug-delivery patch comprising a dissolvable layer and uses thereof
CA2662499A1 (en) * 2008-04-16 2009-10-16 Nitto Denko Corporation Transdermal drug administration device
EP2364317B1 (en) * 2008-08-05 2015-07-29 Effipharma, Inc. Dopamine receptor ligands with enhanced duration of action
WO2010028412A1 (de) 2008-09-15 2010-03-18 Bene Ag Vorrichtung zur verstellung des schwenkwiderstandes einer rückenlehne

Also Published As

Publication number Publication date
CN106176687A (zh) 2016-12-07
EP2506839A2 (de) 2012-10-10
BR112012014107B1 (pt) 2021-03-30
CA2782741A1 (en) 2011-06-09
JP5845190B2 (ja) 2016-01-20
US10772845B2 (en) 2020-09-15
ES2674561T3 (es) 2018-07-02
WO2011066970A3 (de) 2011-10-06
DE102009056746A1 (de) 2011-06-09
BR112012014107A2 (pt) 2016-08-16
WO2011066970A2 (de) 2011-06-09
CA2782741C (en) 2018-07-31
US20120245538A1 (en) 2012-09-27
EP2506839B1 (de) 2018-05-16
CN102639124A (zh) 2012-08-15
JP2013512864A (ja) 2013-04-18

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06T Formal requirements before examination [chapter 6.20 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 30/03/2021, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 02/12/2010 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF