BR112012007338A2 - mecanismo acionador restaurável para um dispositivo de aplicação de fármaco - Google Patents

mecanismo acionador restaurável para um dispositivo de aplicação de fármaco

Info

Publication number
BR112012007338A2
BR112012007338A2 BR112012007338A BR112012007338A BR112012007338A2 BR 112012007338 A2 BR112012007338 A2 BR 112012007338A2 BR 112012007338 A BR112012007338 A BR 112012007338A BR 112012007338 A BR112012007338 A BR 112012007338A BR 112012007338 A2 BR112012007338 A2 BR 112012007338A2
Authority
BR
Brazil
Prior art keywords
drive mechanism
drive
gear
piston
delivery device
Prior art date
Application number
BR112012007338A
Other languages
English (en)
Inventor
Catherine Anne Macdonald
Christopher Jones
Garen Kouyoumjian
George Cave
Robert Veasey
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of BR112012007338A2 publication Critical patent/BR112012007338A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31535Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/31555Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/31556Accuracy improving means
    • A61M5/31558Accuracy improving means using scaling up or down transmissions, e.g. gearbox
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403Ampoule inserted into the ampoule holder
    • A61M2005/2407Ampoule inserted into the ampoule holder from the rear
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2485Ampoule holder connected to rest of syringe
    • A61M2005/2488Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/3152Piston or piston-rod constructions, e.g. connection of piston with piston-rod including gearings to multiply or attenuate the piston displacing force
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31535Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31543Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566Means improving security or handling thereof
    • A61M5/31573Accuracy improving means
    • A61M5/31575Accuracy improving means using scaling up or down transmissions, e.g. gearbox
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T74/00Machine element or mechanism
    • Y10T74/18Mechanical movements
    • Y10T74/18056Rotary to or from reciprocating or oscillating
    • Y10T74/18088Rack and pinion type
    • Y10T74/18128Clutchable gears

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)

Abstract

patente de invenção: mecanismo acionador restaurável para um dispositivo de aplicação de fármaco. a presente invenção refere-se a um mecanismo acionador restarável para uso em um dispositivo de aplicação de fármaco (10). o dispositivo de aplicação de fármaco (10) tendo uma direção distal (14) e uma direção proximal (12). o mecanismo acionador compreende uma cremalheira acionadora (20) engatada com uma engrenagem acionadora (22), uma cremalheira do êmbolo (30) engatada com umaengrenagem do êmbolo (32) e recursos de acoplamento (50) para acoplar a engrenagem acionadora (22) com a engrenagem do êmbolo (32). em um primeiro estado do mecanismo acionador, a engrenagem acionadora (22) e a engrenagem do êmbolo (32) são acopladas e a cremalheira do êmbolo (30) se move na direção distal (14) quando a cremalheira acionadora (20) é movida na direção distal (14). em um segundo estado do mecanismo acionador, a engrenagem acionadora (22) e a engrenagem do êmbolo (32) são desacopladas e a cremalheira do êmbolo (30) fica móvel na direção proximal (12) para restaurar o mecanismo acionador.
BR112012007338A 2009-09-30 2010-09-29 mecanismo acionador restaurável para um dispositivo de aplicação de fármaco BR112012007338A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09171769 2009-09-30
PCT/EP2010/064430 WO2011039237A1 (en) 2009-09-30 2010-09-29 A resettable drive mechanism for a drug delivery device

Publications (1)

Publication Number Publication Date
BR112012007338A2 true BR112012007338A2 (pt) 2016-10-04

Family

ID=41728140

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012007338A BR112012007338A2 (pt) 2009-09-30 2010-09-29 mecanismo acionador restaurável para um dispositivo de aplicação de fármaco

Country Status (9)

Country Link
US (1) US8968259B2 (pt)
EP (1) EP2482898A1 (pt)
JP (1) JP5756471B2 (pt)
CN (1) CN102612382B (pt)
AU (1) AU2010302987B2 (pt)
BR (1) BR112012007338A2 (pt)
CA (1) CA2773462A1 (pt)
IL (1) IL218836A (pt)
WO (1) WO2011039237A1 (pt)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201015799D0 (en) * 2010-09-21 2010-10-27 Owen Mumford Ltd Autoinjectors
EP2468341A1 (en) * 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injector
JP5897297B2 (ja) * 2011-10-07 2016-03-30 高島産業株式会社 歯科用注射器
ES2742046T3 (es) * 2013-03-11 2020-02-12 Antares Pharma Inc Inyector de dosis con sistema de piñón
MX2015012901A (es) 2013-03-14 2016-04-04 Norton Healthcare Ltd Mecanismo de dispensacion para un dispositivo medico.
GB2511806A (en) * 2013-03-14 2014-09-17 Norton Healthcare Ltd Dispensing mechanism for a medical device
US10314980B2 (en) 2013-03-14 2019-06-11 Norton Healthcare Limited Dispensing mechanism for a medical device
CN105209095A (zh) 2013-05-21 2015-12-30 诺和诺德股份有限公司 具有活塞杆联轴器的药物输送装置
WO2014187813A1 (en) 2013-05-21 2014-11-27 Novo Nordisk A/S Frontloaded drug delivery device with dynamic axial stop feature
US20160325041A1 (en) * 2014-01-13 2016-11-10 Novo Nordisk A/S Transmission Arrangement for Motorized Drug Delivery Device
WO2015113149A1 (en) * 2014-01-30 2015-08-06 Medical Injection Devices Inc. Medicament dispensing device
WO2016165914A1 (de) 2015-04-13 2016-10-20 Lock Antriebstechnik Gmbh Getriebevorrichtung zur anbringung an einer antriebswelle
US10894129B2 (en) 2015-12-24 2021-01-19 Phc Holdings Corporation Drug injection device, cartridge adapter, and drug injection system
JP6698105B2 (ja) 2015-12-24 2020-05-27 Phcホールディングス株式会社 薬剤注入装置、カートリッジアダプタおよび薬剤注入システム
JP6867741B2 (ja) * 2017-05-22 2021-05-12 Phcホールディングス株式会社 薬剤注入システム
JP7344535B2 (ja) * 2019-05-20 2023-09-14 株式会社タスク 定量注射筒用プランジャ及び定量注射筒
CN113615572B (zh) * 2021-08-03 2022-04-12 河南中医药大学 一种转基因棉花抗虫鉴定药剂涂抹器

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US3981204A (en) * 1975-01-06 1976-09-21 Starbard Raymond Edward Shock absorber drive unit
US4465478A (en) * 1982-10-14 1984-08-14 Collagen Corporation Syringe force amplification device
FR2683140B1 (fr) * 1991-11-06 1994-02-11 Derien Jean Charles Pistolet doseur.
US6074372A (en) * 1997-06-09 2000-06-13 Novo Nordisk A/S Dose setting mechanism and an injection syringe having such a dose setting mechanism
CA2689022C (en) 2001-05-16 2012-09-18 Eli Lilly And Company Medication injector apparatus with drive assembly that facilitates reset
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Also Published As

Publication number Publication date
US8968259B2 (en) 2015-03-03
IL218836A (en) 2014-11-30
CA2773462A1 (en) 2011-04-07
CN102612382B (zh) 2014-05-07
IL218836A0 (en) 2012-06-28
AU2010302987B2 (en) 2015-01-29
US20120279329A1 (en) 2012-11-08
JP5756471B2 (ja) 2015-07-29
AU2010302987A1 (en) 2012-04-19
WO2011039237A1 (en) 2011-04-07
EP2482898A1 (en) 2012-08-08
JP2013506467A (ja) 2013-02-28
CN102612382A (zh) 2012-07-25

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]