BR102012025421A2 - UPPER MEMBERS 'EQUIPMENT FOR COLLECTION, TREATMENT AND STORAGE OF PARKINSON'S DISEASE CLASSICAL DATA - Google Patents
UPPER MEMBERS 'EQUIPMENT FOR COLLECTION, TREATMENT AND STORAGE OF PARKINSON'S DISEASE CLASSICAL DATA Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/0484—Garment electrodes worn by the patient
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
- A61B5/1101—Detecting tremor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/40—Detecting, measuring or recording for evaluating the nervous system
- A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
- A61B5/4082—Diagnosing or monitoring movement diseases, e.g. Parkinson, Huntington or Tourette
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- A—HUMAN NECESSITIES
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6802—Sensor mounted on worn items
- A61B5/6804—Garments; Clothes
- A61B5/6805—Vests
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36067—Movement disorders, e.g. tremor or Parkinson disease
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0219—Inertial sensors, e.g. accelerometers, gyroscopes, tilt switches
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0261—Strain gauges
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6813—Specially adapted to be attached to a specific body part
- A61B5/6824—Arm or wrist
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Abstract
EQUIPAMENTO DE VESTIR NOS MEMBROS SUPERIORES PARA CAPTAÇÃO, TRATAMENTO E ARMAZENAMENTO DE DADOS QUANTITATIVOS DA TRÍADE CLÁSSICA DA DOENÇA DE PARKINSON. notadamente de um equipamento (1) portátil de vestir nos membros superiores, com função diagnóstica e/ ou tratamento, podendo ser em peça única cobrindo ombro, cotovelo e mão ou em partes ou conjunto de partes (2), sendo constituído de circuitos eletrônicos e sensores estrategicamente posicionados para capturar e armazenar os dados referentes aos padrôes instantâneos de tremor de DP auxiliando o diagnóstico, ou na função de tratamento em que eletrodos (3) colocados na região do antebraço (4) geram sinais elétricos que anulam os sinais de DP.WEARING EQUIPMENT IN THE HIGHER MEMBERS FOR THE COLLECTION, TREATMENT AND STORAGE OF QUANTITATIVE DATA OF THE CLASSIC TRIAD OF PARKINSON'S DISEASE. notably of a portable equipment (1) to wear on the upper limbs, with a diagnostic and / or treatment function, which may be in a single piece covering the shoulder, elbow and hand or in parts or set of parts (2), consisting of electronic circuits and sensors strategically positioned to capture and store data referring to instantaneous PD tremor patterns assisting diagnosis, or in the treatment function in which electrodes (3) placed in the forearm region (4) generate electrical signals that cancel the DP signals.
Description
“EQUIPAMENTO DE VESTIR NOS MEMBROS SUPERIORES PARA CAPTAÇÃO, TRATAMENTO E ARMAZENAMENTO DE DADOS QUANTITATIVOS DA TRÍADE CLÁSSICA DA DOENÇA DE PARKINSON”“UPPER CLOTHING EQUIPMENT FOR COLLECTION, TREATMENT AND STORAGE OF PARKINSON'S DISEASE CLASSICAL DATA”
BREVE APRESENTAÇÃOSHORT PRESENTATION
Trata a presente solicitação de Patente de Invenção de um novoIt deals with the present patent application for a new
EQUIPAMENTO DE VESTIR NOS MEMBROS SUPERIORES PARA CAPTAÇÃO, TRATAMENTO E ARMAZENAMENTO DE DADOS QUANTITATIVOS DA TRÍADE CLÁSSICA DA DOENÇA DE PARKINSON”, notadamente de um equipamento portátil passível de ser vestido nos membros superiores dos pacientes, o qual é 10 dotado de circuitos eletrônicos, sensores e componentes afins capazes de capturar e armazenar dados referentes aos padrões instantâneos de tremor e processá-los por meio de software específico, formando um banco de dados que possibilita fazer avaliação por método quantitativo, possuindo também um conjunto de eletrodos que pela geração de corrente elétrica atuam ativamente na redução dos tremores da 15 doença de Parkinson.TOP CLOTHING WEAR EQUIPMENT FOR PARKINSON CLASSICAL DISEASE QUANTITATIVE DATA COLLECTION, TREATMENT AND STORAGE ”, notably portable equipment that can be worn on the patients' upper limbs, which is equipped with electronic circuits, sensors and related components capable of capturing and storing data related to instantaneous tremor patterns and processing them by means of specific software, forming a database that makes it possible to evaluate by quantitative method, also having a set of electrodes that generate electric current to act actively in reducing tremors of Parkinson's disease.
EMBASAMENTOPACKING
A doença de Parkinson (DP) é uma enfermidade crônica e degenerativa que acomete de 1% a 2% dos indivíduos acima de 60 anos. No mundo somam cerca de 5 milhões de pessoas (Parkinson Foundation) com projeção para 20 40 milhões em 2020 (Morris ME. Movement disorders in people with Parkinsons disease: A model for Physical Therapy intervention. Phys Ther 2000,80:578-597), conseqüência do envelhecimento da população.Parkinson's disease (PD) is a chronic and degenerative disease that affects 1% to 2% of individuals over 60 years. Around 5 million people worldwide (Parkinson Foundation) projected to 20 40 million by 2020 (Morris ME. Movement disorders in people with Parkinsons disease: A model for Physical Therapy intervention. Phys Ther 2000,80: 578-597) , consequence of the aging of the population.
A tríade clássica representada pela rigidez muscular, o tremor de repouso e a bradicinesia (lentidão dos movimentos) são os sintomas motores mais comprometedores da qualidade de vida do paciente com a doença de Parkinson, sendo necessário o auxílio de terceiros para as tarefas mais cotidianas nos casos mais graves.The classic triad represented by muscle stiffness, rest tremor and bradykinesia (slowness of movement) are the most compromising motor symptoms of Parkinson's disease patients' quality of life. more severe cases.
Atualmente, os métodos utilizados na avaliação deste comprometimento são baseados em dados subjetivos, tais como análise clínica e questionários, de suma importância para a definição posológica dos medicamentos e a estimativa do prognóstico.Currently, the methods used to evaluate this impairment are based on subjective data, such as clinical analysis and questionnaires, which are of paramount importance for the definition of the medication and the prognosis estimation.
A Levodopa, principal medicação empregada no tratamento de DP1 causa efeitos colaterais, em média 5 anos após o início do uso, como, por exemplo, a discinesia tardia que também compromete a qualidade de vida. Além disso, a resposta dos pacientes às medicações é bastante variável, dificultando a definição de um padrão posológico.Levodopa, the main medication used to treat DP1, causes side effects, on average 5 years after the start of use, such as late dyskinesia, which also compromises quality of life. In addition, patients' response to medications is quite variable, making it difficult to define a dosage pattern.
Portanto, é imperativo o desenvolvimento de técnicas otimizadas, a fim de que as doses da medicação sejam adequadas a cada caso, desse modo não havendo o uso exagerado e inadvertido de drogas, o que acelera o aparecimento de efeitos colaterais e piora o prognóstico dos pacientes.Therefore, the development of optimized techniques is imperative, so that the doses of medication are appropriate to each case, so there is no excessive and inadvertent use of drugs, which accelerates the appearance of side effects and worsens the prognosis of patients. .
ESTADO DA TÉCNICATECHNICAL STATE
Na literatura médica há relatos de equipamentos projetados para aquisição de dados quantitativos com a finalidade de capturar e armazenar as informações referentes à movimentação e tremores dos pacientes.In the medical literature there are reports of equipment designed to acquire quantitative data for the purpose of capturing and storing patient movement and tremor information.
Um desses métodos é descrito no artigo intitulado “The bilateral reachOne of these methods is described in the article entitled “The bilateral reach
to-grasp movement of Parkinson’s disease subjects” disponível em HTTP://brain.oxfordiournals.ora/content/120/593.full.pdf.to-grasp movement of Parkinson's disease subjects ”available at HTTP: //brain.oxfordiournals.ora/content/120/593.full.pdf.
A publicação acima descreve um sistema que utiliza duas câmeras infravermelhas, fixadas sobre uma mesa e apontada para o paciente. Nos membros superiores são fixados marcadores cujos movimentos são identificados pelas câmeras e mapeados pelo software. O paciente é orientado a executar os movimentos e tudo é registrado pelas câmeras, processado e armazenado por um software, gerando gráficos que mapeiam e identificam os tremores.The above publication describes a system that uses two infrared cameras, fixed on a table and aimed at the patient. Upper limbs are fixed markers whose movements are identified by the cameras and mapped by the software. The patient is oriented to perform the movements and everything is recorded by the cameras, processed and stored by software, generating graphs that map and identify the tremors.
A solução descrita trata de um experimento científico e não constitui 5 um equipamento comercial com a finalidade precípua de medir os tremores. O resultado é altamente dependente da calibração, cujas particularidades são descritas na publicação. A calibração propriamente dita depende da intensidade de Iuz no ambiente no qual o exame é realizado, o que dificulta a replicação em locais que não sejam especificamente projetados para tanto. Além disso, a proposta é 10 baseada em câmeras infravermelhas que têm alto custo, tornando o método menos acessível. Por outro lado, como as câmeras devem ser fixadas a mesas, prejudica a mobilidade e / ou portabilidade do procedimento.The described solution is a scientific experiment and is not a commercial equipment for the primary purpose of measuring tremors. The result is highly dependent on calibration, the particularities of which are described in the publication. Calibration itself depends on the intensity of Iuz in the environment in which the test is performed, which makes replication difficult in locations that are not specifically designed to do so. In addition, the proposal is based on 10 infrared cameras that have high cost, making the method less affordable. On the other hand, as cameras must be fixed to tables, it impairs the mobility and / or portability of the procedure.
O ES 2338092 ATDevice and Method of Biometric Recognition Based on a Movement of the Hand in the Space With a Device that Integrates an Accelerometer” - se presta a captura e armazenamento de informações referentes à movimentação e tremores do paciente. Basicamente é um aparato eletromecânico controlado pela mão ou pelo dedo do paciente, registrando assim os seus tremores.ES 2338092 ATDevice and Method of Biometric Recognition Based on a Movement of the Hand in a Space with a Device that Integrates an Accelerometer ”- provides the capture and storage of information regarding patient movement and tremors. Basically it is an electromechanical apparatus controlled by the patient's hand or finger, thus recording their tremors.
Esse equipamento apresenta como um dos inconvenientes a não portabilidade, o que impõe locais específicos para a realização das avaliações.One of the drawbacks of this equipment is the non portability, which imposes specific places to perform the evaluations.
OBJETIVOS DA PATENTEPATENT OBJECTIVES
Por ser compacto, além de tornar o exame um processo simples de ser aplicado, não dependendo de locais/ instalações específicas, o seu principal diferencial é o de fornecer a aquisição de dados objetivos e quantitativos sobre a frequência e característica do tremor durante 24h ou mais, o que é essencial para a avaliação da eficácia dos métodos terapêuticos utilizados, diminuindo assim a divergência entre os trabalhos publicados, na medida em que reduz a natural incerteza resultado da avaliação subjetiva, atualmente praticada para a verificação destas alterações. Além do sistema diagnóstico, o equipamento também poderá ser utilizado ativamente no tratamento da doença pela Estimulação Elétrica Funcional 5 (FES), em que eletrodos colocados na região do antebraço geram um sinal de corrente elétrica que anula os gerados pela DP.Because it is compact, as well as making the exam a simple process to apply, not depending on specific locations / facilities, its main differential is that it provides objective and quantitative data on tremor frequency and characteristic for 24 hours or more. , which is essential for the evaluation of the efficacy of the therapeutic methods used, thus reducing the divergence between the published works, as it reduces the natural uncertainty resulting from the subjective evaluation currently practiced to verify these changes. In addition to the diagnostic system, the equipment can also be actively used to treat the disease by Functional Electrical Stimulation 5 (FES), in which electrodes placed in the forearm region generate an electrical current signal that nullifies those generated by PD.
A portabilidade do equipamento em tela segue proposta semelhante aos exames do tipo Holter realizados para avaliação elétrica cardíaca e do tipo MAPA para avaliação da pressão arterial.The portability of the equipment in question follows a proposal similar to Holter-type exams performed for cardiac electrical assessment and ABPM for blood pressure assessment.
VANTAGENS DA INVENÇÃOADVANTAGES OF THE INVENTION
> Versatilidade - além de auxiliar no diagnóstico com a captura de dados referentes aos padrões instantâneos de tremor e processá-los, o equipamento atua efetivamente no controle do tremor da doença de Parkinson;> Versatility - In addition to assisting in the diagnosis by capturing data relating to instantaneous tremor patterns and processing them, the equipment effectively controls the tremor of Parkinson's disease;
> Permite que a avaliação do comprometimento motor não seja> Allows the assessment of motor impairment is not
mais realizada apenas por métodos de cunho subjetivo e qualitativo, mas tambémperformed only by subjective and qualitative methods, but also by
com base em método quantitativo capaz de aferir com precisão a intensidade, a frequência e o momento das flutuações motoras;based on a quantitative method capable of accurately measuring the intensity, frequency and timing of motor fluctuations;
> Portabilidade - possibilidade de uso por períodos prolongados> Portability - possibility of use for extended periods
(24h a 72h);(24h to 72h);
> Permite realizar triagens e acompanhamento da eficácia de> Allows screening and monitoring of the efficacy of
tratamentos medicamentosos ou procedimentos terapêuticos de qualquer natureza, cujas variáveis avaliadas sejam rigidez, tremor e bradcinesia (tríade clássica da doença de Parkinson); > A captação dos padrões de movimentação por períodos prolongados é útil para a definição de aspectos temporais como: horários e tempo de resposta de medicamentação, alimentação, sono, etc.;drug treatments or therapeutic procedures of any nature, the variables of which are stiffness, tremor and bradykinesia (classic Parkinson's disease triad); > Capturing movement patterns over prolonged periods is useful for defining temporal aspects such as: medication time and response time, food, sleep, etc .;
> Possibilidade de captura de dados durante exames periódicos em clínicas médicas para conferir valores instantâneos do acometimento do> Possibility of data capture during periodic examinations in medical clinics to check instantaneous values of the involvement of the
paciente;patient;
> Indiretamente possibilita a redução do uso de medicação;> Indirectly enables the reduction of medication use;
> Com a redução do tremor permite que tarefas simples (escrever, dirigir, tomar café e tantas outras) possam ser realizadas pelo portador sem auxílio> With tremor reduction allows simple tasks (writing, driving, drinking coffee and many others) can be performed by the carrier without assistance
de terceiros;of third parties;
> Utiliza sistemas que podem ser vestidos (weareble systems) interferindo o menos possível na rotina do paciente, tais como luvas, cotoveleiras, ombreiras e outros nos quais são colocados os circuitos eletrônicos e sensores, tais como: acelerômetros, giroscópios, sensores de flexão, sensores de torção, etc., sem> Uses weareble systems that interfere as little as possible in the patient's routine, such as gloves, elbow pads, shoulder pads, and others in which electronic circuits and sensors are placed, such as accelerometers, gyros, flexion sensors, torsion sensors, etc., without
interferir na rotina do paciente DESCRICÃO DAS FIGURASinterfere with the patient's routine DESCRIPTION OF THE FIGURES
A invenção será melhor explicada através dos desenhos abaixo relacionados de forma ilustrativa e não limitativa:The invention will be further explained by the following illustrative and non-limiting drawings:
Figura 1: Vista esquemática do equipamento inventado representadoFigure 1: Schematic view of the invented equipment depicted
pela ombreira, cotoveleira e luva, com destaque da central de processamento, transmissão e armazenagem;by the jamb, elbow and glove, highlighting the central processing, transmission and storage;
Figura 2: Vista esquemática do equipamento inventado na versão em que o tratamento é efetivado por eletrodos posicionados na região do antebraço;Figure 2: Schematic view of equipment invented in the version in which treatment is effected by electrodes positioned in the forearm region;
Figura 3: Vista esquemática do equipamento inventado representadoFigure 3: Schematic view of the invented equipment depicted
por uma luva; Figura 4: Vista esquemática do equipamento inventado representado por uma cotoveleira;for a glove; Figure 4: Schematic view of invented equipment represented by an elbow pad;
Figura 5: Vista esquemática do equipamento inventado representado por uma ombreira.Figure 5: Schematic view of invented equipment represented by a jamb.
DESCRICÃO DETALHADADETAILED DESCRIPTION
O “EQUIPAMENTO DE VESTIR NOS MEMBROS SUPERIORES PARA CAPTAÇÃO, TRATAMENTO E ARMAZENAMENTO DE DADOS QUANTITATIVOS DA TRÍADE CLÁSSICA DA DOENÇA DE PARKINSON”; notadamente de um equipamento (1) portátil de vestir nos membros superiores, com 10 função diagnostica el ou tratamento, podendo ser em peça única cobrindo ombro, cotovelo e mão ou em partes ou conjunto de partes (2), sendo constituído de circuitos eletrônicos e sensores estrategicamente posicionados para capturar e armazenar os dados referentes aos padrões instantâneos de tremor de DP auxiliando o diagnóstico, ou na função de tratamento em que eletrodos (3) colocados 15 na região do antebraço (4) geram sinais elétricos que anulam os sinais de DP.The “upper-body dressing equipment for the collection, treatment and storage of quantitative data from the classical parkinson's disease triad”; notably portable upper limb dressing equipment (1), with a diagnostic function or treatment, which may be in a single piece covering shoulder, elbow and hand or in parts or set of parts (2), consisting of electronic circuits and Sensors strategically positioned to capture and store data regarding instantaneous DP tremor patterns assisting diagnosis, or the treatment function where electrodes (3) placed 15 in the forearm region (4) generate electrical signals that nullify DP signals. .
Mais particularmente, o equipamento (1) aqui reivindicado é de construtividade compacta e do tipo de vestir nos membros superiores das pessoas, podendo ser em peça única ou em partes ou conjunto de partes (2) representadas por ombreiras (5), cotoveleiras (6) e luvas (7) nas quais se denotam circuitos 20 eletrônicos e sensores, tais como acelerômetros (8), giroscópios (9), sensores de flexão (10), sensores de torção (11) e outros capazes de realizar um muItissensoriamento dos parâmetros funcionais do processo motor do paciente ou potencial paciente com DP, além de eletrodos (3) na região do antebraço (4) com a função de tratar a DP pela emissão de sinais elétricos. Basicamente, o equipamento 25 (1 e 2) pode ser dividido em quatro módulos, sendo um módulo dos sensores, um módulo de captura e armazenamento dos dados, um módulo de download e análise das informações capturadas e um módulo de tratamento. Desse modo, acelerômetros (8), giroscópios (9), sensores de flexão (10), sensores de torção (11) compõem o módulo dos sensores para monitoramento do deslocamento e giro nos 5 eixos x, y e z, movimentos de flexão, de extensão, de supinação, de pronação, de abdução e adução de articulações. Para que o módulo de captura seja efetivo faz-se necessário o uso de circuitos amplificadores, filtros para tratamento de ruídos e conversores A/D, de forma que os sinais aquisitados nos sensores sejam convertidos para sinais que são tratados digitalmente por um microcontrolador, que 10 então os convertem em informações e as transfere para um computador via cabo, tecnologia USB ou tecnologia sem fio. As informações capturadas e armazenadas em uma central (12) são disponibilizadas em um software proprietário, desenvolvido especificamente para o trabalho e análise gráfica dos dados, com o objetivo de traçar um perfil de atividade motora em grupos de pacientes tidos como saudáveis 15 ou enfermos. O sistema disponibiliza gráficos, resultados de exames, histórico do paciente e todos os demais recursos necessários à atividade médica relacionada a DP.More particularly, the equipment (1) claimed herein is of compact constructivity and wearable on the upper limbs of the person, and may be in one piece or in parts or set of parts (2) represented by shoulder pads (5), elbow pads (6 ) and gloves (7) in which electronic circuits and sensors are denoted, such as accelerometers (8), gyros (9), flexion sensors (10), twist sensors (11) and others capable of multi-sensing the parameters. function of the patient's motor process or potential patient with PD, as well as electrodes (3) in the forearm region (4) to treat PD by emitting electrical signals. Basically, the equipment 25 (1 and 2) can be divided into four modules, being a sensor module, a data capture and storage module, a captured information download and analysis module and a treatment module. Thus, accelerometers (8), gyros (9), bending sensors (10), torsion sensors (11) make up the sensor module for monitoring the displacement and gyration in the 5 x, y and z axes, flexion and extension movements. , supination, pronation, abduction and adduction of joints. For the capture module to be effective it is necessary to use amplifier circuits, noise treatment filters and A / D converters, so that the signals acquired in the sensors are converted to signals that are digitally treated by a microcontroller, 10 then converts it to information and transfers it to a computer via cable, USB technology, or wireless technology. The information captured and stored in a center (12) is made available in proprietary software, developed specifically for the work and graphical analysis of the data, in order to draw a profile of motor activity in groups of patients considered healthy 15 or sick. The system provides graphs, test results, patient history, and all other resources needed for PD-related medical activity.
No modo de tratamento, o equipamento (1) atua de forma ativa no paciente, em que eletrodos (3) posicionados no antebraço (4) fornecem um sinal de 20 amplitude equivalente, porém defasado em relação aos impulsos que originam os tremores da DP. Essa tecnologia, largamente utilizada pelos fisioterapeutas, é conhecida como Estimulação Elétrica Funcional (FES). A teoria e prática do controle ativo de ruído visam reduzir a interferência resultante em um sistema por meio da geração de um sinal de cancelamento secundário, que se oponha ao sinal primário 25 procedente da fonte geradora da perturbação. Este sinal primário é constituído pelos impulsos involuntários gerados nas estruturas musculares que originam o tremor da DP, e objetiva-se a construção de um sistema capaz de gerar um sinal de cancelamento secundário, cujo resultado é um método que possibilita a redução da medicação e, consequentemente, do comprometimento motor, resultando numa 5 melhor qualidade de vida do paciente portador de DP e maior tempo de uso de doses baixas de medicação, o que com certeza retardará o aparecimento dos efeitos colaterais.In treatment mode, the equipment (1) acts actively on the patient, where electrodes (3) positioned on the forearm (4) provide an equivalent amplitude signal, but out of phase with the impulses that cause PD tremors. This technology, widely used by physiotherapists, is known as Functional Electrical Stimulation (FES). Active noise control theory and practice aims to reduce the resulting interference in a system by generating a secondary cancellation signal that opposes the primary signal 25 from the disturbing source. This primary signal is constituted by the involuntary impulses generated in the muscular structures that originate the tremor of PD, and aims to construct a system capable of generating a secondary cancellation signal, the result of which is a method that enables the reduction of medication and, consequently, motor impairment, resulting in a better quality of life of the patient with PD and longer use of low doses of medication, which will certainly delay the onset of side effects.
Claims (9)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR102012025421A BR102012025421A2 (en) | 2012-10-05 | 2012-10-05 | UPPER MEMBERS 'EQUIPMENT FOR COLLECTION, TREATMENT AND STORAGE OF PARKINSON'S DISEASE CLASSICAL DATA |
| PCT/BR2013/000405 WO2014053041A1 (en) | 2012-10-05 | 2013-10-07 | Equipment worn on the upper limbs for sensing, processing and storing quantitative data regarding the classic triad of symptoms of parkinson's disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR102012025421A BR102012025421A2 (en) | 2012-10-05 | 2012-10-05 | UPPER MEMBERS 'EQUIPMENT FOR COLLECTION, TREATMENT AND STORAGE OF PARKINSON'S DISEASE CLASSICAL DATA |
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| BR102012025421A2 true BR102012025421A2 (en) | 2014-10-07 |
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| BR102012025421A BR102012025421A2 (en) | 2012-10-05 | 2012-10-05 | UPPER MEMBERS 'EQUIPMENT FOR COLLECTION, TREATMENT AND STORAGE OF PARKINSON'S DISEASE CLASSICAL DATA |
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| Country | Link |
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| BR (1) | BR102012025421A2 (en) |
| WO (1) | WO2014053041A1 (en) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107427261A (en) * | 2015-04-14 | 2017-12-01 | 伊耐斯克泰克-计算机科学与技术***工程研究所 | The tetanic assessment equipment of wrist for Deep brain stimulation operation |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112015017042B1 (en) | 2013-01-21 | 2022-03-03 | Cala Health, Inc | Device to treat tremor |
| EP4360697A1 (en) | 2014-06-02 | 2024-05-01 | Cala Health, Inc. | Systems and methods for peripheral nerve stimulation to treat tremor |
| ES2839129T3 (en) | 2014-12-22 | 2021-07-05 | Gyrogear Ltd | Tremor Stabilization Devices and Methods |
| AU2016275135C1 (en) | 2015-06-10 | 2021-09-30 | Cala Health, Inc. | Systems and methods for peripheral nerve stimulation to treat tremor with detachable therapy and monitoring units |
| US10603482B2 (en) * | 2015-09-23 | 2020-03-31 | Cala Health, Inc. | Systems and methods for peripheral nerve stimulation in the finger or hand to treat hand tremors |
| IL286747B2 (en) | 2016-01-21 | 2024-05-01 | Cala Health Inc | Wearable device for treating urinary symptoms |
| AU2017293799B2 (en) | 2016-07-08 | 2022-10-20 | Cala Health, Inc. | Systems and methods for stimulating n nerves with exactly n electrodes and improved dry electrodes |
| WO2018050632A1 (en) * | 2016-09-15 | 2018-03-22 | Politecnico Di Milano | Rehabilitation apparatus for upper limb |
| US11331480B2 (en) | 2017-04-03 | 2022-05-17 | Cala Health, Inc. | Systems, methods and devices for peripheral neuromodulation for treating diseases related to overactive bladder |
| US11857778B2 (en) | 2018-01-17 | 2024-01-02 | Cala Health, Inc. | Systems and methods for treating inflammatory bowel disease through peripheral nerve stimulation |
| CN109965882A (en) * | 2019-03-12 | 2019-07-05 | 南京大学 | A kind of Parkinson's disease method of real-time based on instantaneous frequency stability parameter |
| US11890468B1 (en) | 2019-10-03 | 2024-02-06 | Cala Health, Inc. | Neurostimulation systems with event pattern detection and classification |
| CN111150368B (en) * | 2019-12-31 | 2022-07-08 | 西北工业大学 | Processing method of flexible vibration sensor for monitoring Parkinson's syndrome |
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| AU2003243003A1 (en) * | 2003-06-20 | 2005-01-04 | Nadeem Mohammad Qadir | Human-assistive wearable audio-visual inter-communication apparatus. |
| GB0724971D0 (en) * | 2007-12-21 | 2008-01-30 | Dupleix As | Monitoring method and apparatus |
| WO2011150502A2 (en) * | 2010-06-04 | 2011-12-08 | Toronto Rehabilitation Institute | Functional electrical stimulation device and system, and use thereof |
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2012
- 2012-10-05 BR BR102012025421A patent/BR102012025421A2/en not_active Application Discontinuation
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- 2013-10-07 WO PCT/BR2013/000405 patent/WO2014053041A1/en active Application Filing
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107427261A (en) * | 2015-04-14 | 2017-12-01 | 伊耐斯克泰克-计算机科学与技术***工程研究所 | The tetanic assessment equipment of wrist for Deep brain stimulation operation |
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| WO2014053041A1 (en) | 2014-04-10 |
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