BR0317342A - Benzodioxepinas substituìdas - Google Patents
Benzodioxepinas substituìdasInfo
- Publication number
- BR0317342A BR0317342A BR0317342-9A BR0317342A BR0317342A BR 0317342 A BR0317342 A BR 0317342A BR 0317342 A BR0317342 A BR 0317342A BR 0317342 A BR0317342 A BR 0317342A
- Authority
- BR
- Brazil
- Prior art keywords
- benzodioxepines
- substituted
- receptor
- benzodioxepins
- solvates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
"BENZODIOXEPINAS SUBSTITUìDAS". A presente invenção refere-se a benzodioxepinas de fórmula (I) e sais e solvatos fisiologicamente tolerados das mesmas, em que R¬ 1¬,R¬ 2¬,R¬ 3¬, R¬ 4¬, A, B, a e b possuem os significados indicados na reivindicação 1, que são ligantes dos receptores 5HT1A e/ou receptores 5HT4 com forte inibição simultânea de reabsorção de serotonina. Elas podem ser empregadas para o tratamento e profilaxia de várias doenças.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02028596 | 2002-12-20 | ||
PCT/EP2003/013373 WO2004058746A1 (de) | 2002-12-20 | 2003-11-27 | Substituierte benzdioxepine |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0317342A true BR0317342A (pt) | 2005-11-08 |
Family
ID=32668730
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0317342-9A BR0317342A (pt) | 2002-12-20 | 2003-11-27 | Benzodioxepinas substituìdas |
Country Status (16)
Country | Link |
---|---|
US (1) | US7253202B2 (pt) |
EP (1) | EP1572685B1 (pt) |
JP (1) | JP4575167B2 (pt) |
KR (1) | KR20050084438A (pt) |
CN (1) | CN1729187A (pt) |
AR (1) | AR042554A1 (pt) |
AT (1) | ATE350379T1 (pt) |
AU (1) | AU2003289904B2 (pt) |
BR (1) | BR0317342A (pt) |
CA (1) | CA2511021C (pt) |
DE (1) | DE50306228D1 (pt) |
ES (1) | ES2280824T3 (pt) |
MX (1) | MXPA05006433A (pt) |
PL (1) | PL377325A1 (pt) |
WO (1) | WO2004058746A1 (pt) |
ZA (1) | ZA200505786B (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7227023B2 (en) * | 2003-04-30 | 2007-06-05 | Wyeth | Quinoline 3-amino chroman derivatives |
CN106243088B (zh) | 2015-06-03 | 2019-01-04 | 广东东阳光药业有限公司 | 取代的哌嗪化合物及其使用方法和用途 |
PL443018A1 (pl) * | 2022-12-01 | 2024-06-03 | Uniwersytet Medyczny W Lublinie | Pochodne N-((9-chloro-3,4-dihydro-2H-benzo[b][1,4]dioksepin-7-ylo)metylo)-2-(6-fluoro-1H-indol-3-ylo)etano-1-aminy, sposób ich wytwarzania i zastosowanie |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3700691A (en) * | 1969-06-09 | 1972-10-24 | Frosst & Co Charles E | 3,3-disubstituted-3,4-dihydrobenzodioxepins |
US3812150A (en) * | 1969-06-09 | 1974-05-21 | Frosst & Co | 3,3-disubstituted-benzodioxepins |
US3944560A (en) * | 1972-05-01 | 1976-03-16 | Merck & Co., Inc. | 3-Hydroxy-3-(1,2,5-thiadiazolyloxyalkanol)-3,4-dihydro-2H-1,5-benzodioxepin products |
GB2007656B (en) | 1977-11-05 | 1982-05-19 | Pfizer Ltd | Therapeutic agents |
DK166779B1 (da) * | 1983-12-14 | 1993-07-12 | Takeda Chemical Industries Ltd | 1,5-benzoxatiepinderivater eller farmaceutisk acceptable salte deraf, samt farmaceutisk praeparat indeholdende en saadan forbindelse |
JP2865341B2 (ja) * | 1988-12-28 | 1999-03-08 | サントリー株式会社 | ベンゾオキサゼピン誘導体 |
JP3732554B2 (ja) * | 1994-07-07 | 2006-01-05 | 旭化成ファーマ株式会社 | 新規な2,3−ジヒドロベンゾフラン誘導体、その製造方法および用途 |
WO1996001816A1 (fr) * | 1994-07-07 | 1996-01-25 | Asahi Kasei Kogyo Kabushiki Kaisha | Nouveau derive de 2,3-dihydrobenzofuranne, son procede de production et son utilisation |
DE10217006A1 (de) | 2002-04-16 | 2003-11-06 | Merck Patent Gmbh | Substituierte Indole |
-
2003
- 2003-11-27 CN CNA200380106988XA patent/CN1729187A/zh active Pending
- 2003-11-27 KR KR1020057011542A patent/KR20050084438A/ko not_active Application Discontinuation
- 2003-11-27 PL PL377325A patent/PL377325A1/pl not_active Application Discontinuation
- 2003-11-27 AU AU2003289904A patent/AU2003289904B2/en not_active Ceased
- 2003-11-27 WO PCT/EP2003/013373 patent/WO2004058746A1/de active IP Right Grant
- 2003-11-27 DE DE50306228T patent/DE50306228D1/de not_active Expired - Lifetime
- 2003-11-27 CA CA2511021A patent/CA2511021C/en not_active Expired - Fee Related
- 2003-11-27 JP JP2004562656A patent/JP4575167B2/ja not_active Expired - Fee Related
- 2003-11-27 MX MXPA05006433A patent/MXPA05006433A/es not_active Application Discontinuation
- 2003-11-27 US US10/539,515 patent/US7253202B2/en not_active Expired - Fee Related
- 2003-11-27 BR BR0317342-9A patent/BR0317342A/pt not_active Application Discontinuation
- 2003-11-27 EP EP03782241A patent/EP1572685B1/de not_active Expired - Lifetime
- 2003-11-27 AT AT03782241T patent/ATE350379T1/de not_active IP Right Cessation
- 2003-11-27 ES ES03782241T patent/ES2280824T3/es not_active Expired - Lifetime
- 2003-12-19 AR ARP030104740A patent/AR042554A1/es unknown
-
2005
- 2005-07-19 ZA ZA200505786A patent/ZA200505786B/en unknown
Also Published As
Publication number | Publication date |
---|---|
US7253202B2 (en) | 2007-08-07 |
CA2511021A1 (en) | 2004-07-15 |
AU2003289904B2 (en) | 2009-12-10 |
PL377325A1 (pl) | 2006-01-23 |
AU2003289904A1 (en) | 2004-07-22 |
ZA200505786B (en) | 2006-04-26 |
EP1572685A1 (de) | 2005-09-14 |
ES2280824T3 (es) | 2007-09-16 |
WO2004058746A1 (de) | 2004-07-15 |
US20060167078A1 (en) | 2006-07-27 |
CA2511021C (en) | 2012-08-21 |
DE50306228D1 (de) | 2007-02-15 |
AR042554A1 (es) | 2005-06-22 |
KR20050084438A (ko) | 2005-08-26 |
JP2006512380A (ja) | 2006-04-13 |
EP1572685B1 (de) | 2007-01-03 |
CN1729187A (zh) | 2006-02-01 |
MXPA05006433A (es) | 2005-08-19 |
JP4575167B2 (ja) | 2010-11-04 |
ATE350379T1 (de) | 2007-01-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |