BR0316010A - Combinação - Google Patents
CombinaçãoInfo
- Publication number
- BR0316010A BR0316010A BR0316010-6A BR0316010A BR0316010A BR 0316010 A BR0316010 A BR 0316010A BR 0316010 A BR0316010 A BR 0316010A BR 0316010 A BR0316010 A BR 0316010A
- Authority
- BR
- Brazil
- Prior art keywords
- docetaxel
- prodrug
- derivative
- relates
- cdk inhibitor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Abstract
"COMBINAçãO". A presente invenção refere-se a uma combinação compreendendo docetaxel, ou um seu derivado ou pró-droga, e Inibidor de CDK. Um segundo aspecto da invenção refere-se a um produto farmacêutico compreendendo docetaxel, ou um seu derivado ou pró-droga, e um inibidor de CDK como uma preparação combinada para uso simultâneo, seq³encial ou separado em terapia. Um terceiro aspecto da invenção refere-se a um método de tratamento de um distúrbio proliferativo, o dito método compreendendo administrar simultaneamente, seq³encialmente ou separadamente docetaxel, ou um seu derivado ou pró-droga, e um inibidor de CDK a um indivíduo.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0225872.1A GB0225872D0 (en) | 2002-11-06 | 2002-11-06 | Combination |
GB0318813A GB0318813D0 (en) | 2003-08-11 | 2003-08-11 | Combination |
PCT/GB2003/004780 WO2004041268A1 (en) | 2002-11-06 | 2003-11-05 | Combination comprising docetaxel and a cdk inhibitor |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0316010A true BR0316010A (pt) | 2005-09-13 |
Family
ID=32313983
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0316010-6A BR0316010A (pt) | 2002-11-06 | 2003-11-05 | Combinação |
Country Status (11)
Country | Link |
---|---|
US (1) | US20050277656A1 (pt) |
EP (1) | EP1558242B1 (pt) |
JP (1) | JP4764165B2 (pt) |
AT (1) | ATE418333T1 (pt) |
AU (1) | AU2003276467A1 (pt) |
BR (1) | BR0316010A (pt) |
CA (1) | CA2502973A1 (pt) |
DE (1) | DE60325502D1 (pt) |
ES (1) | ES2318202T3 (pt) |
MX (1) | MXPA05004917A (pt) |
WO (1) | WO2004041268A1 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0012528D0 (en) * | 2000-05-23 | 2000-07-12 | Univ Palackeho | Triterpenoid derivatives |
US20070287718A1 (en) * | 2003-11-06 | 2007-12-13 | Green Simon R | Methods for the Treatment of Multiple Myeloma Using Roscovitine |
JP5537035B2 (ja) * | 2006-02-10 | 2014-07-02 | ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ | Cdk阻害剤、および成長因子抗体または抗有糸***剤を含む組合せ |
EP2596801B1 (en) * | 2006-10-06 | 2018-05-02 | Bavarian Nordic A/S | Recombinant modified vaccinia ankara virus encoding a her-2 antigen for use in treating cancer |
EP2178531A4 (en) * | 2007-07-02 | 2012-01-11 | Yu Ming | METHODS AND COMPOSITIONS, TARGETS FOR COMBINED CANCER TREATMENTS |
EP2874631A1 (en) | 2012-05-15 | 2015-05-27 | Cyclacel Limited | Dosage regimen for sapacitabine and seliciclib |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2741881B1 (fr) * | 1995-12-01 | 1999-07-30 | Centre Nat Rech Scient | Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques |
US6235776B1 (en) * | 1998-11-12 | 2001-05-22 | Cell Pathways, Inc. | Method for treating a patient with neoplasia by treatment with a paclitaxel derivative |
GB9904932D0 (en) * | 1999-03-04 | 1999-04-28 | Glaxo Group Ltd | Composition and method for preventing/reducing the severity of side effects of chemotherapy and/or radiation therapy |
JP2004538247A (ja) * | 2000-12-08 | 2004-12-24 | ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー | セミカルバジド及びサイクリン依存キナーゼ阻害剤 |
UY27220A1 (es) * | 2001-03-23 | 2002-09-30 | Aventis Pharma Sa | Combinación de un taxano con una quinasa ciclina-dependiente |
US6949558B2 (en) * | 2001-11-07 | 2005-09-27 | Yale University | Enhancement of taxane-based chemotherapy by a CDK1 antagonist |
CN1652844A (zh) * | 2002-03-15 | 2005-08-10 | 西克拉塞尔有限公司 | 用于癌症治疗的cdk抑制剂和5-fu的联合 |
CA2502979A1 (en) * | 2002-11-06 | 2004-05-21 | Cyclacel Limited | Pharmaceutical composition comprising a cdk inhibitor and gemcitabine |
GB0225873D0 (en) * | 2002-11-06 | 2002-12-11 | Cyclacel Ltd | Combination |
BR0316021A (pt) * | 2002-11-06 | 2005-09-27 | Cyclacel Ltd | Comibinação compreendendo um inibidor de cdk e cisplatina |
-
2003
- 2003-11-05 ES ES03810527T patent/ES2318202T3/es not_active Expired - Lifetime
- 2003-11-05 WO PCT/GB2003/004780 patent/WO2004041268A1/en active Application Filing
- 2003-11-05 EP EP03810527A patent/EP1558242B1/en not_active Expired - Fee Related
- 2003-11-05 CA CA002502973A patent/CA2502973A1/en not_active Abandoned
- 2003-11-05 AU AU2003276467A patent/AU2003276467A1/en not_active Abandoned
- 2003-11-05 JP JP2005502134A patent/JP4764165B2/ja not_active Expired - Fee Related
- 2003-11-05 DE DE60325502T patent/DE60325502D1/de not_active Expired - Lifetime
- 2003-11-05 AT AT03810527T patent/ATE418333T1/de not_active IP Right Cessation
- 2003-11-05 MX MXPA05004917A patent/MXPA05004917A/es unknown
- 2003-11-05 BR BR0316010-6A patent/BR0316010A/pt not_active Application Discontinuation
-
2005
- 2005-05-03 US US11/122,331 patent/US20050277656A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP4764165B2 (ja) | 2011-08-31 |
ES2318202T3 (es) | 2009-05-01 |
MXPA05004917A (es) | 2005-08-18 |
ATE418333T1 (de) | 2009-01-15 |
EP1558242A1 (en) | 2005-08-03 |
US20050277656A1 (en) | 2005-12-15 |
WO2004041268A1 (en) | 2004-05-21 |
AU2003276467A1 (en) | 2004-06-07 |
EP1558242B1 (en) | 2008-12-24 |
CA2502973A1 (en) | 2004-05-21 |
JP2006508186A (ja) | 2006-03-09 |
DE60325502D1 (de) | 2009-02-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |