BR0312778A - Composição farmacêutica para prevenção ou tratamento de arteriosclerose ou doenças derivadas de arteriosclerose, e, usos de um antagonista de receptor de adp e de um inibidor de acat - Google Patents
Composição farmacêutica para prevenção ou tratamento de arteriosclerose ou doenças derivadas de arteriosclerose, e, usos de um antagonista de receptor de adp e de um inibidor de acatInfo
- Publication number
- BR0312778A BR0312778A BR0312778-8A BR0312778A BR0312778A BR 0312778 A BR0312778 A BR 0312778A BR 0312778 A BR0312778 A BR 0312778A BR 0312778 A BR0312778 A BR 0312778A
- Authority
- BR
- Brazil
- Prior art keywords
- atherosclerosis
- receptor antagonist
- acat inhibitor
- adp receptor
- prevention
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"COMPOSIçãO FARMACêUTICA PARA PREVENçãO OU TRATAMENTO DE ARTERIOSCLEROSE OU DOENçAS DERIVADAS DE ARTERIOSCLEROSE, E, USOS DE UM ANTAGONISTA DE RECEPTOR DE ADP E DE UM INIBIDOR DE ACAT". Uma composição medicinal caracterizada pelo fato de que um antagonista do receptor de ADP e um inibidor de ACAT são administrados, ou simultaneamente ou separadamente, em um intervalo definido. Uma composição medicinal, em que um antagonista do receptor de ADP e um inibidor de ACAT são administrados, ou simultaneamente ou separadamente, em um intervalo definido, e útil como um agente preventivo ou um remédio (em particular, um remédio) para arteriosclerose ou doenças derivadas de arteriosclerose, tais como doença cardíaca isquêmica, doença cerebral isquêmica e falha de circulação periférica em animais de sangue quente (em particular, humanos).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002209165 | 2002-07-18 | ||
PCT/JP2003/009108 WO2004009119A1 (ja) | 2002-07-18 | 2003-07-17 | 動脈硬化症治療のための医薬組成物 |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0312778A true BR0312778A (pt) | 2005-05-03 |
Family
ID=30767676
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0312778-8A BR0312778A (pt) | 2002-07-18 | 2003-07-17 | Composição farmacêutica para prevenção ou tratamento de arteriosclerose ou doenças derivadas de arteriosclerose, e, usos de um antagonista de receptor de adp e de um inibidor de acat |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP1555032A1 (pt) |
KR (1) | KR20050025604A (pt) |
CN (1) | CN1681533A (pt) |
AU (1) | AU2003248077A1 (pt) |
BR (1) | BR0312778A (pt) |
CA (1) | CA2493384A1 (pt) |
IL (1) | IL166312A0 (pt) |
MX (1) | MXPA05000726A (pt) |
NO (1) | NO20050877L (pt) |
PL (1) | PL373383A1 (pt) |
RU (1) | RU2005104432A (pt) |
TW (1) | TW200407135A (pt) |
WO (1) | WO2004009119A1 (pt) |
ZA (1) | ZA200500431B (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200600497A (en) * | 2001-02-02 | 2006-01-01 | Sankyo Co | Preparation of indoline derivative |
MXPA05014086A (es) * | 2005-12-20 | 2007-06-20 | Leopoldo De Jesus Espinosa Abdala | Composiciones farmaceuticas que comprenden sustancias antiagregantes plaquetarios combinadas para su uso en el tratamiento y prevencion de eventos vasculares de origen isquemico. |
KR101647842B1 (ko) * | 2006-12-07 | 2016-08-11 | 다이이찌 산쿄 가부시키가이샤 | 저장 안정성이 개선된 의약 조성물 |
BRPI0719393B8 (pt) * | 2006-12-07 | 2021-05-25 | Daiichi Sankyo Co Ltd | composição farmacêutica |
KR101503083B1 (ko) * | 2006-12-07 | 2015-03-16 | 다이이찌 산쿄 가부시키가이샤 | 고형 제제의 제조 방법 |
US20100004279A1 (en) * | 2006-12-07 | 2010-01-07 | Tomoyuki Watanabe | Solid medicinal preparation containing mannitol or lactose |
CA2823981C (en) * | 2006-12-07 | 2016-05-17 | Daiichi Sankyo Company, Limited | Film-coated preparation having improved stability |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62167791A (ja) * | 1986-01-20 | 1987-07-24 | Morinaga Milk Ind Co Ltd | 血小板凝集抑制剤 |
EP0683789B1 (en) * | 1993-02-10 | 1997-11-05 | Astra Pharmaceuticals Limited | N-alkyl-2-substituted atp analogues |
DK0866059T3 (da) * | 1995-10-05 | 2002-03-25 | Kyoto Pharma Ind | Nye heterocykliske derivater og medicinsk anvendelse deraf |
US20020028826A1 (en) * | 2000-06-15 | 2002-03-07 | Robl Jeffrey A. | HMG-CoA reductase inhibitors and method |
CA2703697C (en) * | 2000-07-06 | 2012-09-04 | Daiichi Sankyo Company, Limited | Acid addition salts of hydropyridine derivatives |
-
2003
- 2003-07-17 AU AU2003248077A patent/AU2003248077A1/en not_active Abandoned
- 2003-07-17 EP EP03765315A patent/EP1555032A1/en not_active Withdrawn
- 2003-07-17 PL PL03373383A patent/PL373383A1/xx not_active Application Discontinuation
- 2003-07-17 BR BR0312778-8A patent/BR0312778A/pt not_active Application Discontinuation
- 2003-07-17 CN CNA038218216A patent/CN1681533A/zh active Pending
- 2003-07-17 KR KR1020057000754A patent/KR20050025604A/ko not_active Application Discontinuation
- 2003-07-17 IL IL16631203A patent/IL166312A0/xx unknown
- 2003-07-17 CA CA002493384A patent/CA2493384A1/en not_active Abandoned
- 2003-07-17 RU RU2005104432/15A patent/RU2005104432A/ru not_active Application Discontinuation
- 2003-07-17 MX MXPA05000726A patent/MXPA05000726A/es unknown
- 2003-07-17 WO PCT/JP2003/009108 patent/WO2004009119A1/ja not_active Application Discontinuation
- 2003-07-18 TW TW092119615A patent/TW200407135A/zh unknown
-
2005
- 2005-01-17 ZA ZA200500431A patent/ZA200500431B/xx unknown
- 2005-02-18 NO NO20050877A patent/NO20050877L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ZA200500431B (en) | 2006-08-30 |
MXPA05000726A (es) | 2005-04-08 |
WO2004009119A1 (ja) | 2004-01-29 |
EP1555032A1 (en) | 2005-07-20 |
TW200407135A (en) | 2004-05-16 |
RU2005104432A (ru) | 2005-08-10 |
CN1681533A (zh) | 2005-10-12 |
CA2493384A1 (en) | 2004-01-29 |
NO20050877L (no) | 2005-02-18 |
PL373383A1 (en) | 2005-08-22 |
IL166312A0 (en) | 2006-01-15 |
KR20050025604A (ko) | 2005-03-14 |
AU2003248077A1 (en) | 2004-02-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |