BR0311180A - Métodos para o tratamento de doenças e condições respiratórias utilizando um inibidor seletivo da inos - Google Patents
Métodos para o tratamento de doenças e condições respiratórias utilizando um inibidor seletivo da inosInfo
- Publication number
- BR0311180A BR0311180A BR0311180-6A BR0311180A BR0311180A BR 0311180 A BR0311180 A BR 0311180A BR 0311180 A BR0311180 A BR 0311180A BR 0311180 A BR0311180 A BR 0311180A
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- conditions
- respiratory diseases
- inos
- selective inhibitor
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 208000023504 respiratory system disease Diseases 0.000 title abstract 2
- 101100396994 Drosophila melanogaster Inos gene Proteins 0.000 title 1
- 229940124639 Selective inhibitor Drugs 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000000241 respiratory effect Effects 0.000 abstract 2
- 101000998969 Homo sapiens Inositol-3-phosphate synthase 1 Proteins 0.000 abstract 1
- 102100036881 Inositol-3-phosphate synthase 1 Human genes 0.000 abstract 1
- 229940123134 Nitric oxide inhibitor Drugs 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"MéTODOS PARA O TRATAMENTO DE DOENçAS E CONDIçõES RESPIRATóRIAS UTILIZANDO UM INIBIDOR SELETIVO DA INOS". A presente invenção refere-se a métodos terapêuticos para a prevenção e tratamento de doenças ou condições respiratórias, incluindo os métodos a administração a um paciente necessitado daqueles de uma quantidade eficaz para a doença ou condição respiratória de um inibidor seletivo da óxido nítricosintase indutível.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38105402P | 2002-05-16 | 2002-05-16 | |
PCT/US2003/015369 WO2003097163A2 (en) | 2002-05-16 | 2003-05-16 | Using a selective inos inhibitor for the treatment of respiratory diseases and conditions |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0311180A true BR0311180A (pt) | 2005-03-01 |
Family
ID=29550060
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0311180-6A BR0311180A (pt) | 2002-05-16 | 2003-05-16 | Métodos para o tratamento de doenças e condições respiratórias utilizando um inibidor seletivo da inos |
Country Status (13)
Country | Link |
---|---|
US (1) | US20040077639A1 (pt) |
EP (1) | EP1506040A2 (pt) |
JP (1) | JP2005536467A (pt) |
KR (1) | KR20050004155A (pt) |
CN (1) | CN1652843A (pt) |
AU (1) | AU2003234606A1 (pt) |
BR (1) | BR0311180A (pt) |
CA (1) | CA2486061A1 (pt) |
IL (1) | IL164826A0 (pt) |
MX (1) | MXPA04011404A (pt) |
PL (1) | PL373952A1 (pt) |
WO (1) | WO2003097163A2 (pt) |
ZA (1) | ZA200408905B (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0408177A (pt) * | 2003-03-11 | 2006-03-01 | Pharmacia Corp | sal cristalino de maleato de s-[2-[(1-iminoetil)amino]etil]-2-metil-l-cisteìna de forma ii |
WO2004080953A1 (en) * | 2003-03-11 | 2004-09-23 | Pharmacia Corporation | S-[2-[(1-iminoethyl)amino]ethyl]-2-methyl-l-cysteine salicylate monohydrate crystalline salt |
CN101068559B (zh) * | 2004-07-23 | 2011-08-31 | 福生生物科技股份有限公司 | 红球姜的抗超敏炎症和抗敏活性 |
TWI375671B (en) * | 2010-03-01 | 2012-11-01 | Univ China Medical | Pharmaceutical compositions containing brazilin for inhibiting expression of cytokines of t helper cell type ii and/or inhibiting expression of chemokines and uses of the same |
EP2591777B1 (de) * | 2010-07-09 | 2016-12-14 | Justus-Liebig-Universität Gießen | L-NIL als Inhibitor zur Regeneration der Lunge von an COPD leidenden Patienten |
WO2019054944A1 (en) | 2017-09-12 | 2019-03-21 | Agency For Science, Technology And Research | COMPOUNDS USEFUL AS INHIBITORS OF ISOPRENYLCYSTEINE CARBOXYL METHYLTRANFERASE |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6262784B1 (en) * | 1993-06-01 | 2001-07-17 | Samsung Electronics Co., Ltd | Active matrix display devices having improved opening and contrast ratios and methods of forming same and a storage electrode line |
US5824669A (en) * | 1996-03-22 | 1998-10-20 | Nitromed, Inc. | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders |
US6331543B1 (en) * | 1996-11-01 | 2001-12-18 | Nitromed, Inc. | Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use |
ATE386531T1 (de) * | 1997-02-28 | 2008-03-15 | Nycomed Gmbh | Synergistische kombination von pde-hemmern und adenylatcyclase-agonisten bzw. guanylcyclyse- agonisten |
GB9811599D0 (en) * | 1998-05-30 | 1998-07-29 | Glaxo Group Ltd | Nitric oxide synthase inhibitors |
US6403830B2 (en) * | 2000-03-24 | 2002-06-11 | Pharmacia Corporation | Amidino compound and salts thereof useful as nitric oxide synthase inhibitors |
AR032318A1 (es) * | 2000-04-13 | 2003-11-05 | Pharmacia Corp | Compuesto derivado halogenado del acido 2-amino-5,6 heptenoico; composicion farmaceutica que lo comprende y su uso en la fabricacion de un medicamento util como inhibidor de la oxido nitrico sintetasa |
US6545170B2 (en) * | 2000-04-13 | 2003-04-08 | Pharmacia Corporation | 2-amino-5, 6 heptenoic acid derivatives useful as nitric oxide synthase inhibitors |
EA005817B1 (ru) * | 2000-08-01 | 2005-06-30 | Фармасиа Корпорейшн | Производные гексагидро-7-1h-азепин-2-илгексановой (или гексеновой) кислоты в качестве ингибиторов индуцибельной синтазы оксида азота |
AR031609A1 (es) * | 2000-09-15 | 2003-09-24 | Pharmacia Corp | Derivados de acido 2-amino-2-alquil-3 heptenoico y heptinoico utiles como inhibidores de oxido nitrico sintetasa |
AR035585A1 (es) * | 2000-09-15 | 2004-06-16 | Pharmacia Corp | Derivados del acido 2-amino-2-alquil-4-heptenoico, composicion farmaceutica y su uso en la fabricacion de medicamentos |
MY131964A (en) * | 2000-09-15 | 2007-09-28 | Pharmacia Corp | 2-amino-2-alkyl-5 heptenoic and heptynoic acid derivatives useful as nitric oxide synthase inhibitors |
-
2003
- 2003-05-16 BR BR0311180-6A patent/BR0311180A/pt not_active IP Right Cessation
- 2003-05-16 EP EP03728948A patent/EP1506040A2/en not_active Withdrawn
- 2003-05-16 JP JP2004505156A patent/JP2005536467A/ja not_active Abandoned
- 2003-05-16 MX MXPA04011404A patent/MXPA04011404A/es not_active Application Discontinuation
- 2003-05-16 US US10/439,669 patent/US20040077639A1/en not_active Abandoned
- 2003-05-16 CA CA002486061A patent/CA2486061A1/en not_active Abandoned
- 2003-05-16 KR KR10-2004-7018523A patent/KR20050004155A/ko not_active Application Discontinuation
- 2003-05-16 IL IL16482603A patent/IL164826A0/xx unknown
- 2003-05-16 CN CNA038111969A patent/CN1652843A/zh active Pending
- 2003-05-16 WO PCT/US2003/015369 patent/WO2003097163A2/en active Application Filing
- 2003-05-16 PL PL03373952A patent/PL373952A1/xx not_active Application Discontinuation
- 2003-05-16 AU AU2003234606A patent/AU2003234606A1/en not_active Abandoned
-
2004
- 2004-11-03 ZA ZA200408905A patent/ZA200408905B/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP1506040A2 (en) | 2005-02-16 |
US20040077639A1 (en) | 2004-04-22 |
MXPA04011404A (es) | 2005-02-14 |
ZA200408905B (en) | 2006-06-28 |
JP2005536467A (ja) | 2005-12-02 |
CN1652843A (zh) | 2005-08-10 |
CA2486061A1 (en) | 2003-11-27 |
AU2003234606A1 (en) | 2003-12-02 |
PL373952A1 (en) | 2005-09-19 |
IL164826A0 (en) | 2005-12-18 |
WO2003097163A3 (en) | 2004-10-21 |
KR20050004155A (ko) | 2005-01-12 |
WO2003097163A2 (en) | 2003-11-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2051 DE 27/04/2010. |
|
B15K | Others concerning applications: alteration of classification |
Ipc: A61K 31/198 (2006.01), A61P 11/00 (2006.01), A61P |