BR0215937A - Substância fki-1033, processo para sua produção, seu uso, microorganismo consistindo em verticillium sp fki-1033, agente inibidor de ligação de rianodina, agente inseticida e anti-helmìntico, e agente inibidor de ligação de rianodina, inseticida e anti-helmìntico - Google Patents
Substância fki-1033, processo para sua produção, seu uso, microorganismo consistindo em verticillium sp fki-1033, agente inibidor de ligação de rianodina, agente inseticida e anti-helmìntico, e agente inibidor de ligação de rianodina, inseticida e anti-helmìnticoInfo
- Publication number
- BR0215937A BR0215937A BR0215937-6A BR0215937A BR0215937A BR 0215937 A BR0215937 A BR 0215937A BR 0215937 A BR0215937 A BR 0215937A BR 0215937 A BR0215937 A BR 0215937A
- Authority
- BR
- Brazil
- Prior art keywords
- fki
- anthelmintic
- agent
- binding inhibitory
- substance
- Prior art date
Links
- 239000000126 substance Substances 0.000 title abstract 5
- 229930001406 Ryanodine Natural products 0.000 title abstract 2
- 230000000507 anthelmentic effect Effects 0.000 title abstract 2
- 230000000749 insecticidal effect Effects 0.000 title abstract 2
- 244000005700 microbiome Species 0.000 title abstract 2
- JJSYXNQGLHBRRK-SFEDZAPPSA-N ryanodine Chemical compound O([C@@H]1[C@]([C@@]2([C@]3(O)[C@]45O[C@@]2(O)C[C@]([C@]4(CC[C@H](C)[C@H]5O)O)(C)[C@@]31O)C)(O)C(C)C)C(=O)C1=CC=CN1 JJSYXNQGLHBRRK-SFEDZAPPSA-N 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 title 2
- 230000002401 inhibitory effect Effects 0.000 title 2
- 239000002917 insecticide Substances 0.000 title 2
- 241000082085 Verticillium <Phyllachorales> Species 0.000 title 1
- 239000000921 anthelmintic agent Substances 0.000 title 1
- 229940124339 anthelmintic agent Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 2
- 239000003905 agrochemical Substances 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 239000000273 veterinary drug Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/145—Fungal isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/14—Nitrogen or oxygen as hetero atom and at least one other diverse hetero ring atom in the same ring
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
Abstract
"SUBSTâNCIA FKI-1033, PROCESSO PARA SUA PRODUçãO, SEU USO, MICROORGANISMO CONSISTINDO EM VERTICILLIUM SP FKI-1033, AGENTE INIBIDOR DE LIGAçãO DE RIANODINA, AGENTE INSETICIDA E ANTI-HELMìNTICO, E AGENTE INIBIDOR DE LIGAçãO DE RIANODINA, INSETICIDA E ANTI-HELMìNTICO". A presente invenção refere-se ao cultivo de microorganismos capazes de produzirem uma substância FKI-1033 representada pela fórmula: em um meio de cultura, acumulação da substância FKI-1033 no meio de cultura, isolando-se posteriormente a substância FKI-1033 da massa de cultura. A substância FKI-1033 assim obtida apresenta atividade inibidora de ligação de rianodina, atividade como inseticida e atividade anti-helmíntica, sendo prevista sua utilização em produtos químicos para aplicações agrícolas, drogas para aplicações em veterinária, e medicamentos, com utilidade sob os pontos de vista de eficácia e de toxicidade.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP2002/011777 WO2004044214A1 (ja) | 2002-11-12 | 2002-11-12 | 新規ｆｋｉ−１０３３物質およびその製造法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0215937A true BR0215937A (pt) | 2005-09-06 |
Family
ID=32310251
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0215937-6A BR0215937A (pt) | 2002-11-12 | 2002-11-12 | Substância fki-1033, processo para sua produção, seu uso, microorganismo consistindo em verticillium sp fki-1033, agente inibidor de ligação de rianodina, agente inseticida e anti-helmìntico, e agente inibidor de ligação de rianodina, inseticida e anti-helmìntico |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7541336B2 (pt) |
| EP (1) | EP1561820B1 (pt) |
| JP (1) | JP4176077B2 (pt) |
| AT (1) | ATE419373T1 (pt) |
| BR (1) | BR0215937A (pt) |
| CA (1) | CA2504309A1 (pt) |
| DE (1) | DE60230686D1 (pt) |
| ES (1) | ES2318053T3 (pt) |
| MX (1) | MXPA05005032A (pt) |
| NO (1) | NO20052150L (pt) |
| NZ (1) | NZ539986A (pt) |
| WO (1) | WO2004044214A1 (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602005014124D1 (de) * | 2004-09-07 | 2009-06-04 | Banyu Pharma Co Ltd | Carbamoylsubstituiertes spiro-derivat |
| JP2014037351A (ja) * | 2010-12-10 | 2014-02-27 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | 新規デプシペプチドｐｆ１４４２物質およびその製造法 |
| JP6300207B2 (ja) | 2012-06-13 | 2018-03-28 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | 新規環状デプシペプチド誘導体およびそれを含んでなる有害生物防除剤 |
| WO2015093558A1 (ja) * | 2013-12-18 | 2015-06-25 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | 環状デプシペプチド誘導体およびそれを含んでなる有害生物防除剤 |
| WO2018237394A1 (en) * | 2017-06-23 | 2018-12-27 | Vanderbilt University | VERTICILIDE ENANTIOMER AND METHODS OF INHIBITING INTRACELLULAR CALCIUM RELEASE WITH RYANODINE RECEPTOR MEDIATION |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO176766C (no) | 1989-02-07 | 1995-05-24 | Meiji Seika Kaisha | Fremgangsmåte for fremstilling av en forbindelse med anthelmintaktivitet |
| DE4317432A1 (de) * | 1993-05-26 | 1994-12-01 | Bayer Ag | Octacyclodepsipeptide mit endoparasitizider Wirkung |
| DE10008128A1 (de) * | 2000-02-22 | 2001-08-23 | Bayer Ag | Endoparasitizide Mittel |
| DE10031044A1 (de) * | 2000-06-26 | 2002-01-03 | Bayer Ag | Endoparasitizide Mittel zur freiwilligen oralen Aufnahme durch Tiere |
-
2002
- 2002-11-12 BR BR0215937-6A patent/BR0215937A/pt not_active IP Right Cessation
- 2002-11-12 US US10/532,662 patent/US7541336B2/en not_active Expired - Fee Related
- 2002-11-12 DE DE60230686T patent/DE60230686D1/de not_active Expired - Lifetime
- 2002-11-12 EP EP02780072A patent/EP1561820B1/en not_active Expired - Lifetime
- 2002-11-12 MX MXPA05005032A patent/MXPA05005032A/es active IP Right Grant
- 2002-11-12 CA CA002504309A patent/CA2504309A1/en not_active Abandoned
- 2002-11-12 ES ES02780072T patent/ES2318053T3/es not_active Expired - Lifetime
- 2002-11-12 WO PCT/JP2002/011777 patent/WO2004044214A1/ja active IP Right Grant
- 2002-11-12 JP JP2004551171A patent/JP4176077B2/ja not_active Expired - Fee Related
- 2002-11-12 AT AT02780072T patent/ATE419373T1/de not_active IP Right Cessation
- 2002-11-12 NZ NZ539986A patent/NZ539986A/en not_active IP Right Cessation
-
2005
- 2005-05-02 NO NO20052150A patent/NO20052150L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004044214A1 (ja) | 2004-05-27 |
| NO20052150L (no) | 2005-06-10 |
| JPWO2004044214A1 (ja) | 2006-03-09 |
| US7541336B2 (en) | 2009-06-02 |
| NZ539986A (en) | 2007-03-30 |
| EP1561820B1 (en) | 2008-12-31 |
| MXPA05005032A (es) | 2008-02-05 |
| ES2318053T3 (es) | 2009-05-01 |
| EP1561820A1 (en) | 2005-08-10 |
| ATE419373T1 (de) | 2009-01-15 |
| AU2002344494A1 (en) | 2004-06-03 |
| US20060111280A1 (en) | 2006-05-25 |
| EP1561820A4 (en) | 2007-08-22 |
| DE60230686D1 (de) | 2009-02-12 |
| CA2504309A1 (en) | 2004-05-27 |
| JP4176077B2 (ja) | 2008-11-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 9A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2138 DE 27/12/2011. |