BR0214212A - Criação de órgãos reprodutores femininos construìdos por tecido - Google Patents
Criação de órgãos reprodutores femininos construìdos por tecidoInfo
- Publication number
- BR0214212A BR0214212A BR0214212-0A BR0214212A BR0214212A BR 0214212 A BR0214212 A BR 0214212A BR 0214212 A BR0214212 A BR 0214212A BR 0214212 A BR0214212 A BR 0214212A
- Authority
- BR
- Brazil
- Prior art keywords
- female reproductive
- reproductive organs
- creation
- fabric
- tissue
- Prior art date
Links
- 230000001850 reproductive effect Effects 0.000 title abstract 6
- 210000000056 organ Anatomy 0.000 title abstract 5
- 239000004744 fabric Substances 0.000 title 1
- 206010010356 Congenital anomaly Diseases 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000003679 cervix uteri Anatomy 0.000 abstract 1
- 210000004748 cultured cell Anatomy 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 210000002919 epithelial cell Anatomy 0.000 abstract 1
- 210000005002 female reproductive tract Anatomy 0.000 abstract 1
- 230000036244 malformation Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000003101 oviduct Anatomy 0.000 abstract 1
- 210000000329 smooth muscle myocyte Anatomy 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
- 210000004291 uterus Anatomy 0.000 abstract 1
- 210000001215 vagina Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
- A61L27/3679—Hollow organs, e.g. bladder, esophagus, urether, uterus, intestine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3826—Muscle cells, e.g. smooth muscle cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
- A61L27/3891—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types as distinct cell layers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/22—Materials or treatment for tissue regeneration for reconstruction of hollow organs, e.g. bladder, esophagus, urether, uterus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/70—Undefined extracts
- C12N2500/80—Undefined extracts from animals
- C12N2500/84—Undefined extracts from animals from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1347—Smooth muscle cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/24—Genital tract cells, non-germinal cells from gonads
- C12N2502/243—Cells of the female genital tract, non-germinal ovarian cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
- C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Veterinary Medicine (AREA)
- Botany (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Prostheses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"CRIAçãO DE ORGãOS REPRODUTORES FEMININOS CONSTRUIDOS POR TECIDO". A invenção refere-se às composições e métodos para reconstruir os órgãos reprodutores femininos artificiais. Os constructos e métodos da invenção podem ser usados para melhorar as malformações congênitas e distúrbios do trato reprodutor feminino usando órgãos reprodutores femininos construídos por tecido, tal como o útero, vagina, cervix e tubos de falópio. Estes órgãos reprodutores femininos construídos por tecido podem ser gerados perfundindo-se populações de célula cultivada derivadas de células dos tecidos reprodutores femininos, tal como células epiteliais de tubo de falópio, cervicais, vaginais, uterinas bem como células de músculo liso.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33150301P | 2001-11-16 | 2001-11-16 | |
PCT/US2002/036965 WO2003043675A1 (en) | 2001-11-16 | 2002-11-15 | Creation of tissue engineered female reproductive organs |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0214212A true BR0214212A (pt) | 2004-10-26 |
Family
ID=23294238
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0214212-0A BR0214212A (pt) | 2001-11-16 | 2002-11-15 | Criação de órgãos reprodutores femininos construìdos por tecido |
Country Status (12)
Country | Link |
---|---|
US (3) | US7806937B2 (pt) |
EP (1) | EP1448247B1 (pt) |
JP (1) | JP4065846B2 (pt) |
KR (1) | KR20050044498A (pt) |
CN (2) | CN1294996C (pt) |
AT (1) | ATE498415T1 (pt) |
AU (1) | AU2002343749B2 (pt) |
BR (1) | BR0214212A (pt) |
CA (1) | CA2467558C (pt) |
DE (1) | DE60239217D1 (pt) |
HK (1) | HK1077524A1 (pt) |
WO (1) | WO2003043675A1 (pt) |
Families Citing this family (75)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1294996C (zh) * | 2001-11-16 | 2007-01-17 | 儿童医疗中心有限公司 | 组织改造雌性生殖器官的建造 |
US20030180268A1 (en) * | 2002-02-05 | 2003-09-25 | Anthony Atala | Tissue engineered construct for supplementing or replacing a damaged organ |
EP1513927A4 (en) * | 2002-05-23 | 2007-02-28 | Advanced Cell Tech Inc | CREATION OF HISTOCOMPATIBLE TISSUES BY NUCLEAR TRANSPLANTATION |
DE10333863A1 (de) * | 2003-07-24 | 2005-02-17 | Walles, Thorsten Dr. Med. | Bioartifizielles, primär vaskularisiertes Testgewebe für pharmakologische Testverfahren, Verfahren zu dessen Herstellung und Testverfahren unter dessen Verwendung sowie Bioreaktor zur Durchführung der Verfahren |
PT1699915E (pt) * | 2003-12-30 | 2010-08-31 | Augustinus Bader | Utilização de eritropoietina para a regeneração de tecido hepático |
EP1550715A1 (de) * | 2003-12-30 | 2005-07-06 | Bionethos Holding Gmbh | Verfahren zur Regenation von Gewebe |
US7759120B2 (en) * | 2005-03-02 | 2010-07-20 | Kps Bay Medical, Inc. | Seeding implantable medical devices with cells |
US20060199265A1 (en) * | 2005-03-02 | 2006-09-07 | Wolf Michael F | Seeding implantable medical devices with cells |
US20100093066A1 (en) * | 2005-08-26 | 2010-04-15 | Regents Of The University Of Minnesota | Decellularization and recellularization apparatuses and systems containing the same |
EP2431063B1 (en) | 2005-08-26 | 2015-06-17 | Regents of the University of Minnesota | Decellularization and recellularization of organs and tissues |
US8096967B2 (en) * | 2006-02-02 | 2012-01-17 | Milan Radojicic | Tissue engineered cerebrospinal fluid shunt |
US8764697B2 (en) | 2006-02-01 | 2014-07-01 | Agathos Holdings Llc | Systems and methods for an advanced medical device |
CA2641733C (en) * | 2006-02-10 | 2015-03-31 | Tengion, Inc. | Scaffolds for organ reconstruction and augmentation |
US9555167B2 (en) * | 2006-12-11 | 2017-01-31 | 3M Innovative Properties Company | Biocompatible antimicrobial compositions |
US20080200890A1 (en) * | 2006-12-11 | 2008-08-21 | 3M Innovative Properties Company | Antimicrobial disposable absorbent articles |
US8926606B2 (en) * | 2009-04-09 | 2015-01-06 | Virginia Tech Intellectual Properties, Inc. | Integration of very short electric pulses for minimally to noninvasive electroporation |
US10238447B2 (en) | 2008-04-29 | 2019-03-26 | Virginia Tech Intellectual Properties, Inc. | System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress |
US10702326B2 (en) | 2011-07-15 | 2020-07-07 | Virginia Tech Intellectual Properties, Inc. | Device and method for electroporation based treatment of stenosis of a tubular body part |
US10245098B2 (en) | 2008-04-29 | 2019-04-02 | Virginia Tech Intellectual Properties, Inc. | Acute blood-brain barrier disruption using electrical energy based therapy |
US10272178B2 (en) | 2008-04-29 | 2019-04-30 | Virginia Tech Intellectual Properties Inc. | Methods for blood-brain barrier disruption using electrical energy |
US11254926B2 (en) | 2008-04-29 | 2022-02-22 | Virginia Tech Intellectual Properties, Inc. | Devices and methods for high frequency electroporation |
US10448989B2 (en) | 2009-04-09 | 2019-10-22 | Virginia Tech Intellectual Properties, Inc. | High-frequency electroporation for cancer therapy |
US11272979B2 (en) | 2008-04-29 | 2022-03-15 | Virginia Tech Intellectual Properties, Inc. | System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies |
US9283051B2 (en) | 2008-04-29 | 2016-03-15 | Virginia Tech Intellectual Properties, Inc. | System and method for estimating a treatment volume for administering electrical-energy based therapies |
US9867652B2 (en) | 2008-04-29 | 2018-01-16 | Virginia Tech Intellectual Properties, Inc. | Irreversible electroporation using tissue vasculature to treat aberrant cell masses or create tissue scaffolds |
US8992517B2 (en) | 2008-04-29 | 2015-03-31 | Virginia Tech Intellectual Properties Inc. | Irreversible electroporation to treat aberrant cell masses |
US10117707B2 (en) | 2008-04-29 | 2018-11-06 | Virginia Tech Intellectual Properties, Inc. | System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies |
US9198733B2 (en) | 2008-04-29 | 2015-12-01 | Virginia Tech Intellectual Properties, Inc. | Treatment planning for electroporation-based therapies |
EP2280741A4 (en) * | 2008-04-29 | 2012-06-13 | Virginia Tech Intell Prop | IRREVERSIBLE ELECTROPORATION FOR THE PRODUCTION OF TISSUE OBJECTS |
US8795264B2 (en) * | 2008-07-01 | 2014-08-05 | Ralph Zipper | Method for decreasing the size and/or changing the shape of pelvic tissues |
CN104328050B (zh) * | 2008-07-16 | 2017-12-15 | 儿童医疗中心有限公司 | 具有微通道的器官模仿装置及其使用和制造方法 |
WO2010072417A2 (en) * | 2008-12-24 | 2010-07-01 | Augustinus Bader | Rapid preparation and use of engineered tissue and scaffolds as individual implants |
US11638603B2 (en) | 2009-04-09 | 2023-05-02 | Virginia Tech Intellectual Properties, Inc. | Selective modulation of intracellular effects of cells using pulsed electric fields |
US11382681B2 (en) | 2009-04-09 | 2022-07-12 | Virginia Tech Intellectual Properties, Inc. | Device and methods for delivery of high frequency electrical pulses for non-thermal ablation |
US8903488B2 (en) | 2009-05-28 | 2014-12-02 | Angiodynamics, Inc. | System and method for synchronizing energy delivery to the cardiac rhythm |
US9895189B2 (en) | 2009-06-19 | 2018-02-20 | Angiodynamics, Inc. | Methods of sterilization and treating infection using irreversible electroporation |
US20110065809A1 (en) * | 2009-09-15 | 2011-03-17 | Medtronic, Inc. | Polymerization of Multifunctional Azides, and Polymers Therefrom |
CN101712946B (zh) * | 2009-09-27 | 2013-02-27 | 南通大学附属医院 | 构建生殖结节器官培养尿道体外发育模型的方法 |
JP2013521882A (ja) * | 2010-03-09 | 2013-06-13 | テンジオン, インク. | 細胞足場構築体 |
AU2011295779B2 (en) | 2010-09-01 | 2015-08-27 | Regents Of The University Of Minnesota | Methods of recellularizing a tissue or organ for improved transplantability |
TW201219573A (en) * | 2010-09-22 | 2012-05-16 | Ct Hospitalier Universitaire Vaudois | Anti-fibrotic response provided by fetal cells to implants and delivery systems |
US20120089238A1 (en) | 2010-10-06 | 2012-04-12 | Hyun-Wook Kang | Integrated organ and tissue printing methods, system and apparatus |
EP2627274B1 (en) | 2010-10-13 | 2022-12-14 | AngioDynamics, Inc. | System for electrically ablating tissue of a patient |
EP2661623A4 (en) * | 2010-11-15 | 2014-04-30 | Sanofi Pasteur Vaxdesign Corp | UROGENITAL IN VITRO COCULTURE MODELS |
EP3498818A1 (en) | 2011-02-28 | 2019-06-19 | President and Fellows of Harvard College | Cell culture system |
US9078665B2 (en) | 2011-09-28 | 2015-07-14 | Angiodynamics, Inc. | Multiple treatment zone ablation probe |
US9725687B2 (en) | 2011-12-09 | 2017-08-08 | President And Fellows Of Harvard College | Integrated human organ-on-chip microphysiological systems |
US9972219B2 (en) | 2012-04-30 | 2018-05-15 | Laerdal Global Health As | Postpartum uterus model |
US9290738B2 (en) | 2012-06-13 | 2016-03-22 | Miromatrix Medical Inc. | Methods of decellularizing bone |
US9775864B2 (en) | 2013-01-31 | 2017-10-03 | Ams Research Corporation | Vaginal laxity therapy utilizing cell-based bulking compositions |
US9532901B2 (en) | 2013-02-05 | 2017-01-03 | Mor Research Applications Ltd. | Fertility preservation device |
US10213525B2 (en) | 2013-03-15 | 2019-02-26 | Micromatrix Medical, Inc. | Use of perfusion decellularized liver for islet cell recellularization |
US9855554B2 (en) | 2013-07-22 | 2018-01-02 | President And Fellows Of Harvard College | Microfluidic cartridge assembly |
EP3083940A4 (en) | 2013-12-20 | 2017-08-23 | President and Fellows of Harvard College | Low shear microfluidic devices and methods of use and manufacturing thereof |
WO2015175570A1 (en) | 2014-05-12 | 2015-11-19 | Virginia Tech Intellectual Properties, Inc. | Selective modulation of intracellular effects of cells using pulsed electric fields |
EP3169626A4 (en) | 2014-07-14 | 2018-04-04 | President and Fellows of Harvard College | Systems and methods for improved performance of fluidic and microfluidic systems |
WO2016044421A1 (en) * | 2014-09-18 | 2016-03-24 | National Health Research Institutes | Progenitor cells, method for preparation thereof and uses thereof |
US10694972B2 (en) | 2014-12-15 | 2020-06-30 | Virginia Tech Intellectual Properties, Inc. | Devices, systems, and methods for real-time monitoring of electrophysical effects during tissue treatment |
WO2016123362A1 (en) | 2015-01-30 | 2016-08-04 | Northwestern University | Artificial ovary |
JP6494393B2 (ja) * | 2015-04-21 | 2019-04-03 | 学校法人東京女子医科大学 | 子宮組織治療用細胞組成物及びその製造方法 |
RU2587723C1 (ru) * | 2015-07-03 | 2016-06-20 | Федеральное государственное бюджетное учреждение "Научный центр акушерства, гинекологии и перинатологии имени академика В.И. Кулакова" Министерства здравоохранения Российской Федерации | Усовершенствованная методика операции кольпопоэза из тазовой брюшины с лапароскопической ассистенцией |
US10202569B2 (en) | 2015-07-24 | 2019-02-12 | President And Fellows Of Harvard College | Radial microfluidic devices and methods of use |
AU2017290785B2 (en) | 2016-07-01 | 2021-11-25 | The Board Of Regents Of The University Of Texas System | Methods, apparatuses, and systems for creating 3-dimensional representations exhibiting geometric and surface characteristics of brain lesions |
US11278643B2 (en) | 2016-09-06 | 2022-03-22 | Mayo Foundation For Medical Education And Research | Use of resected liver serum for whole liver-engineering |
AU2017326179B2 (en) | 2016-09-13 | 2022-12-08 | President And Fellows Of Harvard College | Methods relating to intestinal organ-on-a-chip |
US10905492B2 (en) | 2016-11-17 | 2021-02-02 | Angiodynamics, Inc. | Techniques for irreversible electroporation using a single-pole tine-style internal device communicating with an external surface electrode |
JP7031138B2 (ja) | 2017-05-11 | 2022-03-08 | 株式会社リコー | 脱細胞化組織の製造方法、及び脱細胞化組織の製造装置 |
CN109749980B (zh) * | 2017-11-07 | 2022-03-25 | 深圳先进技术研究院 | 一种能够激活原始卵泡的3d打印人造卵巢生物支架及其人造卵巢和用途 |
US11607537B2 (en) | 2017-12-05 | 2023-03-21 | Virginia Tech Intellectual Properties, Inc. | Method for treating neurological disorders, including tumors, with electroporation |
US11925405B2 (en) | 2018-03-13 | 2024-03-12 | Virginia Tech Intellectual Properties, Inc. | Treatment planning system for immunotherapy enhancement via non-thermal ablation |
US11311329B2 (en) | 2018-03-13 | 2022-04-26 | Virginia Tech Intellectual Properties, Inc. | Treatment planning for immunotherapy based treatments using non-thermal ablation techniques |
US11950835B2 (en) | 2019-06-28 | 2024-04-09 | Virginia Tech Intellectual Properties, Inc. | Cycled pulsing to mitigate thermal damage for multi-electrode irreversible electroporation therapy |
TW202233828A (zh) | 2020-11-12 | 2022-09-01 | 日商Adeka股份有限公司 | 去細胞化組織組成物 |
US11998662B1 (en) | 2021-06-09 | 2024-06-04 | Reprise Biomedical, Inc. | Biologic matrix for a wound site and related methods |
TW202306575A (zh) | 2021-06-23 | 2023-02-16 | 日商Adeka股份有限公司 | 去細胞化細胞結構體 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5863531A (en) * | 1986-04-18 | 1999-01-26 | Advanced Tissue Sciences, Inc. | In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework |
US5266480A (en) * | 1986-04-18 | 1993-11-30 | Advanced Tissue Sciences, Inc. | Three-dimensional skin culture system |
US5567612A (en) * | 1986-11-20 | 1996-10-22 | Massachusetts Institute Of Technology | Genitourinary cell-matrix structure for implantation into a human and a method of making |
CA1340581C (en) * | 1986-11-20 | 1999-06-08 | Joseph P. Vacanti | Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices |
US5106949A (en) | 1989-09-15 | 1992-04-21 | Organogenesis, Inc. | Collagen compositions and methods for preparation thereof |
AU2900792A (en) * | 1991-10-24 | 1993-05-21 | Children's Medical Center Corporation | Neomorphogenesis of urological structures in vivo from cell culture |
US5581833A (en) * | 1994-11-04 | 1996-12-10 | Zenoff; Andrew R. | Support pillow with lumbar support for use in nursing and other applications |
US5855610A (en) * | 1995-05-19 | 1999-01-05 | Children's Medical Center Corporation | Engineering of strong, pliable tissues |
EP1032435B1 (en) * | 1997-10-31 | 2003-09-03 | Children's Medical Center Corporation | Bladder reconstruction |
FR2779340B1 (fr) | 1998-06-04 | 2000-12-29 | Delab | Dispositif intraluminal implantable |
ES2323662T3 (es) * | 1998-06-05 | 2009-07-22 | Organogenesis Inc. | Protesis de injerto vascular producidas por bioingenieria. |
US6428802B1 (en) * | 1999-12-29 | 2002-08-06 | Children's Medical Center Corp. | Preparing artificial organs by forming polylayers of different cell populations on a substrate |
US20030166274A1 (en) * | 2001-11-15 | 2003-09-04 | Hewitt Charles W. | Three-dimensional matrix for producing living tissue equivalents |
CN1294996C (zh) * | 2001-11-16 | 2007-01-17 | 儿童医疗中心有限公司 | 组织改造雌性生殖器官的建造 |
-
2002
- 2002-11-15 CN CNB028272242A patent/CN1294996C/zh not_active Expired - Fee Related
- 2002-11-15 CA CA002467558A patent/CA2467558C/en not_active Expired - Fee Related
- 2002-11-15 WO PCT/US2002/036965 patent/WO2003043675A1/en active IP Right Grant
- 2002-11-15 JP JP2003545353A patent/JP4065846B2/ja not_active Expired - Fee Related
- 2002-11-15 CN CNA2006101628634A patent/CN1962858A/zh active Pending
- 2002-11-15 DE DE60239217T patent/DE60239217D1/de not_active Expired - Lifetime
- 2002-11-15 AT AT02780711T patent/ATE498415T1/de not_active IP Right Cessation
- 2002-11-15 EP EP02780711A patent/EP1448247B1/en not_active Expired - Lifetime
- 2002-11-15 BR BR0214212-0A patent/BR0214212A/pt not_active IP Right Cessation
- 2002-11-15 AU AU2002343749A patent/AU2002343749B2/en not_active Ceased
- 2002-11-15 KR KR1020047007478A patent/KR20050044498A/ko not_active Application Discontinuation
- 2002-11-15 US US10/298,198 patent/US7806937B2/en not_active Expired - Fee Related
- 2002-11-15 US US10/295,812 patent/US7049057B2/en not_active Expired - Fee Related
-
2005
- 2005-02-07 US US11/052,459 patent/US7429490B2/en not_active Expired - Fee Related
- 2005-10-21 HK HK05109414A patent/HK1077524A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US7049057B2 (en) | 2006-05-23 |
CN1615161A (zh) | 2005-05-11 |
DE60239217D1 (de) | 2011-03-31 |
KR20050044498A (ko) | 2005-05-12 |
CA2467558C (en) | 2009-07-14 |
EP1448247A1 (en) | 2004-08-25 |
AU2002343749B2 (en) | 2007-07-12 |
US20050208026A1 (en) | 2005-09-22 |
HK1077524A1 (en) | 2006-02-17 |
JP2005514971A (ja) | 2005-05-26 |
CN1294996C (zh) | 2007-01-17 |
US7429490B2 (en) | 2008-09-30 |
US7806937B2 (en) | 2010-10-05 |
EP1448247B1 (en) | 2011-02-16 |
US20030096406A1 (en) | 2003-05-22 |
WO2003043675A1 (en) | 2003-05-30 |
AU2002343749A1 (en) | 2003-06-10 |
CN1962858A (zh) | 2007-05-16 |
JP4065846B2 (ja) | 2008-03-26 |
CA2467558A1 (en) | 2003-05-30 |
ATE498415T1 (de) | 2011-03-15 |
US20030096407A1 (en) | 2003-05-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0214212A (pt) | Criação de órgãos reprodutores femininos construìdos por tecido | |
CROSBY et al. | Embryology of the Müllerian duct system: review of present-day theory | |
Moore | Before We Are Born: Essentials of Embryology and Birth Defects: First South Asia Edition E-Book | |
US20210154044A1 (en) | Device positionable in the uterine cavity | |
Thiery | Intrauterine contraception: from silver ring to intrauterine contraceptive implant | |
CN109568670A (zh) | 一种子宫内膜损伤修复的水凝胶及其制备方法 | |
Bates et al. | A TECHINQUE FOR UTERINE CONSERVATION IN ADOLESCENTS WITH VAGINAL AGENESIS AND A FUNCTIONAL UTERUS | |
Besenfelder et al. | A method for endoscopic embryo collection and transfer in the rabbit | |
Farber et al. | Congenital absence of the uterine cervix | |
Anspach | Gynecology | |
MXPA04004539A (es) | Creacion de organos reproductores femeninos con tejidos manipulados. | |
CN204542323U (zh) | 可视化胚胎移植装置 | |
Russell et al. | A “sexual skin” in a marmoset | |
CN201529194U (zh) | 形状记忆宫形宫内节育器 | |
CN206080775U (zh) | 宫颈管防狭窄器 | |
Kirschner et al. | PREGNANCY IN A NON‐COMMUNICATING, RUDIMENTARY UTERINE HORN: A reason for failed therapeutic second trimester abortion | |
CN107041807B (zh) | 一种磁性宫腔内装置 | |
CN204133574U (zh) | ***阻断器 | |
Hol et al. | A prospective study to compare levonogestrol intrauterine system and trans-cervical resection of endometrium for treatment of abnormal uterine bleeding | |
CN210466975U (zh) | 用于孕妇经***行子宫颈内口环扎术的操作模型 | |
CN219538645U (zh) | 一种双侧附药物硅橡胶体加筑型宫内节育器 | |
CN202458849U (zh) | 终止妊娠的子宫放置笼 | |
Ahluwalia et al. | A unique case of successful twin pregnancy reaching term in a patient with uterus bicornis unicollis | |
Guzik et al. | Anatomy histological transformations of the cervical mucosa in the prenatal ontogenesis | |
CN2882552Y (zh) | 子宫专用长钳 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 11A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2259 DE 22/04/2014. |