BR0207725A - Promotores do crescimento e/ou da diferenciação de células-tronco hematopoiéticas e/ou progenitores hematopoiéticos - Google Patents

Promotores do crescimento e/ou da diferenciação de células-tronco hematopoiéticas e/ou progenitores hematopoiéticos

Info

Publication number
BR0207725A
BR0207725A BR0207725-6A BR0207725A BR0207725A BR 0207725 A BR0207725 A BR 0207725A BR 0207725 A BR0207725 A BR 0207725A BR 0207725 A BR0207725 A BR 0207725A
Authority
BR
Brazil
Prior art keywords
hematopoietic
differentiation
progenitors
hematopoietic stem
stem cell
Prior art date
Application number
BR0207725-6A
Other languages
English (en)
Inventor
Kenju Miura
Munetada Haruyama
Shiho Kodama
Original Assignee
Daiichi Suntory Biomedical Res
Daiichi Suntory Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Suntory Biomedical Res, Daiichi Suntory Pharma Co Ltd filed Critical Daiichi Suntory Biomedical Res
Publication of BR0207725A publication Critical patent/BR0207725A/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/202—IL-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

"PROMOTORES DO CRESCIMENTO EIOU DA DIFERENCIAçãO DE CéLULAS-TRONCO HEMATOPOIéTICAS E/OU PROGENITORES HEMATOPOIéTICOS". A presente invenção tem como seu objetivo proporcionar promotores do crescimento e/ou da diferenciação de células-tronco hematopoéticas e/ou progenitores hematopoiéticos, os quais são úteis como substâncias terapêuticas de doenças que resultam do crescimento e/ou da diferenciação insuficientes de células-tronco hematopoéticas e/ou progenitores hematopoiéticos, em particular, como substâncias terapêuticas de panhematopenia e/ou doenças que são acompanhadas por hipofunção hematopoética. A invenção atinge o objeto estabelecido proporcionando promotores do crescimento e/ou da diferenciação de células-tronco hematopoéticas e/ou progenitores hematopoiéticos que contêm a Cofilina como um ingrediente ativo.
BR0207725-6A 2001-12-28 2002-12-27 Promotores do crescimento e/ou da diferenciação de células-tronco hematopoiéticas e/ou progenitores hematopoiéticos BR0207725A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001400330 2001-12-28
PCT/JP2002/013862 WO2003057241A1 (fr) 2001-12-28 2002-12-27 Agents favorisant la proliferation et/ou la differenciation de cellules souches hematopoietiques et/ou de precurseurs hematopoietiques

Publications (1)

Publication Number Publication Date
BR0207725A true BR0207725A (pt) 2004-03-23

Family

ID=19189604

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0207725-6A BR0207725A (pt) 2001-12-28 2002-12-27 Promotores do crescimento e/ou da diferenciação de células-tronco hematopoiéticas e/ou progenitores hematopoiéticos

Country Status (13)

Country Link
US (1) US7282201B2 (pt)
EP (1) EP1459758B1 (pt)
JP (1) JP4362066B2 (pt)
KR (1) KR100948346B1 (pt)
CN (1) CN1329078C (pt)
AT (1) ATE423567T1 (pt)
AU (1) AU2002359951B8 (pt)
BR (1) BR0207725A (pt)
CA (1) CA2439471A1 (pt)
DE (1) DE60231328D1 (pt)
ES (1) ES2321819T3 (pt)
IL (1) IL157600A0 (pt)
WO (1) WO2003057241A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7767453B2 (en) * 2004-10-20 2010-08-03 Whitehead Institute For Biomedical Research Cultured hematopoietic stem cells and method for expansion and analysis thereof
JP5139271B2 (ja) * 2005-05-24 2013-02-06 ホワイトヘッド インスティチュート フォー バイオメディカル リサーチ 培養した造血幹細胞を拡大しかつ分析する方法
WO2007032566A1 (ja) * 2005-09-16 2007-03-22 Kenji Yoshida 造血幹細胞増殖剤
DE102006060247A1 (de) * 2006-09-15 2008-03-27 Ossacur Ag Differenzierung von Stammzellen
KR100980849B1 (ko) * 2007-04-25 2010-09-10 가톨릭대학교 산학협력단 인터루킨(ｉｌ)-10을 포함하는 조혈모세포의 자가 재생산을촉진하는 조성물
WO2008137641A2 (en) * 2007-05-04 2008-11-13 Whitehead Institute For Biomedical Research Ex vivo expansion of human hematopoietic stem cells
US8372389B2 (en) * 2007-11-28 2013-02-12 Hadasit Medical Research Services And Development Ltd. Methods for the treatment of radiation or chemotherapy-induced tissue damage
PE20100362A1 (es) 2008-10-30 2010-05-27 Irm Llc Derivados de purina que expanden las celulas madre hematopoyeticas
JP5519994B2 (ja) * 2009-10-19 2014-06-11 日揮株式会社 細胞培養装置及び細胞培養方法
US20130331326A1 (en) * 2011-02-21 2013-12-12 Duke University Method of inducing hematopoietic reconstruction
GB201210857D0 (en) 2012-06-19 2012-08-01 Cambridge Entpr Ltd Transcription factor mediated programming towards megakaryocytes
JP6584956B2 (ja) 2012-12-21 2019-10-02 アステラス インスティテュート フォー リジェネレイティブ メディシン 多能性幹細胞から血小板を生産するための方法およびその組成物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5464817A (en) * 1990-04-11 1995-11-07 Brigham And Women's Hospital Method for reducing the viscosity of pathological mucoid airway contents in the respiratory tract comprising administering actin-binding compounds with or without DNASE I
JPH0550603A (ja) 1991-08-22 1993-03-02 Fujitsu Ltd 印字装置
JP4052680B2 (ja) 1993-03-18 2008-02-27 アスビオファーマ株式会社 新規ヒト白血病細胞株
US5856330A (en) 1996-07-31 1999-01-05 Hoechst Aktiengesellschaft Use of xanthine derivatives for the inhibition of dephosphorylation of cofilin
US6011051A (en) 1996-07-31 2000-01-04 Hoechst Aktiengesellschaft Use of isoxazole and crotonamide derivatives for the modulation of apoptosis
CA2296792A1 (en) * 1999-02-26 2000-08-26 Genset S.A. Expressed sequence tags and encoded human proteins
WO2002053719A2 (en) * 2001-01-04 2002-07-11 Incyte Genomics, Inc. Cytoskeleton-associated proteins
GB0224014D0 (en) * 2002-10-15 2002-11-27 Oxford Glycosciences Uk Ltd A protein involved in therapy

Also Published As

Publication number Publication date
US7282201B2 (en) 2007-10-16
AU2002359951B8 (en) 2008-11-06
CN1329078C (zh) 2007-08-01
EP1459758A1 (en) 2004-09-22
KR20040075700A (ko) 2004-08-30
ES2321819T3 (es) 2009-06-12
AU2002359951B2 (en) 2008-06-19
CN1499980A (zh) 2004-05-26
ATE423567T1 (de) 2009-03-15
JP4362066B2 (ja) 2009-11-11
IL157600A0 (en) 2004-03-28
JPWO2003057241A1 (ja) 2005-05-12
EP1459758B1 (en) 2009-02-25
KR100948346B1 (ko) 2010-03-22
EP1459758A4 (en) 2006-02-22
CA2439471A1 (en) 2003-07-17
DE60231328D1 (de) 2009-04-09
US20040157326A1 (en) 2004-08-12
WO2003057241A1 (fr) 2003-07-17
AU2002359951A1 (en) 2003-07-24

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Owner name: DAIICHI SUNTORY BIOMEDICAL RESEARCH LIMITED (JP) ,

Free format text: A FIM DE ATENDER A PETICAO DE TRANSFERENCIA NO 020050044959/RJ DE 02/06/2005, ESCLARECA A DIVERGENCIA ENTRE O NOME DA EMPRESA CEDENTE COM O NOME DO TITULAR.

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