BR0206469A - Composição injetável para depósito - Google Patents
Composição injetável para depósitoInfo
- Publication number
- BR0206469A BR0206469A BR0206469-3A BR0206469A BR0206469A BR 0206469 A BR0206469 A BR 0206469A BR 0206469 A BR0206469 A BR 0206469A BR 0206469 A BR0206469 A BR 0206469A
- Authority
- BR
- Brazil
- Prior art keywords
- subject
- injectable depot
- depot composition
- gel
- composition
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 230000009286 beneficial effect Effects 0.000 abstract 2
- 239000000969 carrier Substances 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 239000007972 injectable composition Substances 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 230000009974 thixotropic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"COMPOSIçãO INJETáVEL PARA DEPóSITO". São fornecidas composições em gel que podem ser utilizadas como veículos para agentes benéficos quando injetados em um sujeito e que podem fornecer liberação controlada do agente benéfico com o tempo. Em particular, são descritas composições em gel que contêm um agente que torna a composição tixotrópica para facilitar a injeção do gel em um sujeito com desconforto mínimo para o sujeito.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33625401P | 2001-11-14 | 2001-11-14 | |
PCT/US2002/036717 WO2003041685A1 (en) | 2001-11-14 | 2002-11-14 | Injectable depot composition |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0206469A true BR0206469A (pt) | 2004-01-13 |
Family
ID=23315249
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0206469-3A BR0206469A (pt) | 2001-11-14 | 2002-11-14 | Composição injetável para depósito |
Country Status (16)
Country | Link |
---|---|
US (2) | US20030157178A1 (pt) |
EP (1) | EP1446099B1 (pt) |
JP (2) | JP5170935B2 (pt) |
KR (1) | KR20040065153A (pt) |
CN (1) | CN100446809C (pt) |
AU (1) | AU2009201018B2 (pt) |
BR (1) | BR0206469A (pt) |
CA (1) | CA2466642C (pt) |
DE (1) | DE60232987D1 (pt) |
ES (1) | ES2329346T3 (pt) |
IL (1) | IL161999A0 (pt) |
MX (1) | MXPA04004664A (pt) |
NO (1) | NO20033179L (pt) |
NZ (1) | NZ533434A (pt) |
WO (1) | WO2003041685A1 (pt) |
ZA (1) | ZA200306278B (pt) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL162001A0 (en) * | 2001-11-14 | 2005-11-20 | Alza Corp | Catheter injectable depot compositions and uses thereof |
US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
EP2030611A1 (en) | 2002-07-31 | 2009-03-04 | Alza Corporation | Injectable multimodal polymer depot compositions and uses thereof |
KR20050038008A (ko) * | 2002-07-31 | 2005-04-25 | 알자 코포레이션 | 주사용 저장형 조성물 및 이의 용도 |
DE60325511D1 (de) * | 2002-11-06 | 2009-02-05 | Alza Corp | Depot-formulierungen mit verzögerter freisetzung |
US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
FR2850282B1 (fr) | 2003-01-27 | 2007-04-06 | Jerome Asius | Implant injectable a base de ceramique pour le comblement de rides, depressions cutanees et cicatrices, et sa preparation |
DE60311958T2 (de) * | 2003-02-03 | 2007-11-08 | Polaschegg, Hans-Dietrich, Dr. | Zusammensetzung zur Prävention von Infektionen durch subkutane Prothesen |
WO2004108111A1 (en) * | 2003-05-30 | 2004-12-16 | Alza Corporation | Implantable elastomeric depot compositions, uses thereof and method of manufacturing |
ITMI20031302A1 (it) * | 2003-06-26 | 2004-12-27 | Mediolanum Pharmaceuticals Ltd | Uso di etanolo come plasticizzante per preparare impianti sottocutanei contenenti principi attivi termolabili dispersi in una matrice di plga. |
US20050281879A1 (en) * | 2003-11-14 | 2005-12-22 | Guohua Chen | Excipients in drug delivery vehicles |
SI1740213T1 (sl) * | 2004-04-07 | 2012-04-30 | Ares Trading Sa | Tekoäśa formulacija rastnega hormona |
US20050244463A1 (en) | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Sustained release intraocular implants and methods for treating ocular vasculopathies |
US8529927B2 (en) * | 2004-04-30 | 2013-09-10 | Allergan, Inc. | Alpha-2 agonist polymeric drug delivery systems |
CA2596194A1 (en) * | 2004-11-24 | 2006-06-01 | Algorx Pharmaceuticals, Inc. | Capsaicinoid gel formulation and uses thereof |
US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
JP2008528698A (ja) * | 2005-02-03 | 2008-07-31 | インターシア セラピューティクス,インコーポレイティド | 埋め込み可能なインターフェロン含有デバイス |
WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
DE602007009377D1 (de) | 2006-05-30 | 2010-11-04 | Intarcia Therapeutics Inc | Zweiteiliger flussmodulator mit einem internen kanal für ein osmotisches ausgabesystem |
US7682356B2 (en) | 2006-08-09 | 2010-03-23 | Intarcia Therapeutics, Inc. | Osmotic delivery systems and piston assemblies for use therein |
CN100457187C (zh) * | 2006-11-10 | 2009-02-04 | 中国人民解放军第二军医大学 | Vegf缓释注射微球支架及其制备方法和用途 |
JP5351884B2 (ja) | 2007-04-23 | 2013-11-27 | インターシア セラピューティクス,インコーポレイティド | インスリン分泌促進性ペプチドの懸濁製剤及び使用 |
JP5599705B2 (ja) | 2007-05-18 | 2014-10-01 | デュレクト コーポレーション | 改良されたデポー製剤 |
ES2562878T3 (es) | 2007-05-25 | 2016-03-08 | Indivior Uk Limited | Formulaciones de liberación sostenida de compuestos de risperidona |
US20090181068A1 (en) * | 2008-01-14 | 2009-07-16 | Dunn Richard L | Low Viscosity Liquid Polymeric Delivery System |
CA2726861C (en) | 2008-02-13 | 2014-05-27 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
US9095506B2 (en) | 2008-11-17 | 2015-08-04 | Allergan, Inc. | Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof |
HUE035862T2 (en) | 2009-09-28 | 2018-05-28 | Intarcia Therapeutics Inc | Rapid development and / or completion of substantially steady-state drug delivery |
MX361709B (es) | 2009-11-09 | 2018-12-07 | Allergan Inc | Composiciones y metodos para estimular el crecimiento del cabello. |
US9211175B2 (en) * | 2010-07-08 | 2015-12-15 | Covidien Lp | Self-detachable medical devices |
US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
JP6511401B2 (ja) | 2013-02-15 | 2019-05-15 | アラーガン、インコーポレイテッドAllergan,Incorporated | 持続型薬物送達インプラント |
US20140308352A1 (en) | 2013-03-11 | 2014-10-16 | Zogenix Inc. | Compositions and methods involving polymer, solvent, and high viscosity liquid carrier material |
CA2903769A1 (en) | 2013-03-11 | 2014-10-09 | Durect Corporation | Injectable controlled release composition comprising high viscosity liquid carrier |
WO2015018461A1 (fr) | 2013-08-09 | 2015-02-12 | Genbiotech | Compositions therapeutiques comprenant d'acide hyaluronique |
CA2931547A1 (en) | 2013-12-09 | 2015-06-18 | Durect Corporation | Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same |
US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
WO2016179540A1 (en) * | 2015-05-06 | 2016-11-10 | Synagile Corporation | Pharmaceutical suspensions containing drug particles, devices for their administration, and methods of their use |
ES2968262T3 (es) | 2015-06-03 | 2024-05-08 | I2O Therapeutics Inc | Sistemas de colocación de implantes |
WO2017200943A1 (en) | 2016-05-16 | 2017-11-23 | Intarcia Therapeutics, Inc. | Glucagon-receptor selective polypeptides and methods of use thereof |
USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
CN110225762A (zh) | 2017-01-03 | 2019-09-10 | 因塔西亚制药公司 | 包括glp-1受体激动剂的连续施用和药物的共同施用的方法 |
CA3106105A1 (en) | 2018-08-08 | 2020-02-13 | Lanny Leo Johnson | Methods of diagnosing and treating infected implants |
KR20220140711A (ko) | 2020-01-13 | 2022-10-18 | 듀렉트 코퍼레이션 | 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법 |
CN113304325B (zh) * | 2020-02-27 | 2022-03-11 | 四川大学 | 一种集可注射与抗菌于一体的双功能水凝胶及其制备方法和用途 |
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US20070196415A1 (en) * | 2002-11-14 | 2007-08-23 | Guohua Chen | Depot compositions with multiple drug release rate controls and uses thereof |
IL162001A0 (en) * | 2001-11-14 | 2005-11-20 | Alza Corp | Catheter injectable depot compositions and uses thereof |
KR20050038008A (ko) * | 2002-07-31 | 2005-04-25 | 알자 코포레이션 | 주사용 저장형 조성물 및 이의 용도 |
-
2002
- 2002-11-14 US US10/295,159 patent/US20030157178A1/en not_active Abandoned
- 2002-11-14 MX MXPA04004664A patent/MXPA04004664A/es active IP Right Grant
- 2002-11-14 EP EP02784472A patent/EP1446099B1/en not_active Expired - Lifetime
- 2002-11-14 NZ NZ533434A patent/NZ533434A/en not_active IP Right Cessation
- 2002-11-14 DE DE60232987T patent/DE60232987D1/de not_active Expired - Lifetime
- 2002-11-14 KR KR10-2003-7009399A patent/KR20040065153A/ko not_active Application Discontinuation
- 2002-11-14 WO PCT/US2002/036717 patent/WO2003041685A1/en active Application Filing
- 2002-11-14 CN CNB028267974A patent/CN100446809C/zh not_active Expired - Fee Related
- 2002-11-14 JP JP2003543572A patent/JP5170935B2/ja not_active Expired - Fee Related
- 2002-11-14 CA CA2466642A patent/CA2466642C/en not_active Expired - Fee Related
- 2002-11-14 ES ES02784472T patent/ES2329346T3/es not_active Expired - Lifetime
- 2002-11-14 BR BR0206469-3A patent/BR0206469A/pt not_active IP Right Cessation
-
2003
- 2003-07-11 NO NO20033179A patent/NO20033179L/no not_active Application Discontinuation
- 2003-08-13 ZA ZA2003/06278A patent/ZA200306278B/en unknown
-
2004
- 2004-05-13 IL IL16199904A patent/IL161999A0/xx unknown
-
2009
- 2009-03-13 AU AU2009201018A patent/AU2009201018B2/en not_active Ceased
-
2010
- 2010-06-23 JP JP2010142427A patent/JP2010265277A/ja active Pending
-
2013
- 2013-09-19 US US14/032,070 patent/US20140113864A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20030157178A1 (en) | 2003-08-21 |
JP2010265277A (ja) | 2010-11-25 |
EP1446099B1 (en) | 2009-07-15 |
NZ533434A (en) | 2006-11-30 |
CA2466642A1 (en) | 2003-05-22 |
CA2466642C (en) | 2011-01-18 |
MXPA04004664A (es) | 2004-09-10 |
NO20033179L (no) | 2003-09-04 |
ZA200306278B (en) | 2005-03-30 |
JP2005514350A (ja) | 2005-05-19 |
CN1612725A (zh) | 2005-05-04 |
ES2329346T3 (es) | 2009-11-25 |
DE60232987D1 (de) | 2009-08-27 |
JP5170935B2 (ja) | 2013-03-27 |
IL161999A0 (en) | 2005-11-20 |
NO20033179D0 (no) | 2003-07-11 |
WO2003041685A1 (en) | 2003-05-22 |
EP1446099A1 (en) | 2004-08-18 |
AU2009201018B2 (en) | 2011-09-22 |
KR20040065153A (ko) | 2004-07-21 |
US20140113864A1 (en) | 2014-04-24 |
AU2009201018A1 (en) | 2009-04-09 |
CN100446809C (zh) | 2008-12-31 |
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