BR0206364A - Métodos para tratar doenças auto-imunes em um indivìduo e testes diagnósticos in vitro - Google Patents

Métodos para tratar doenças auto-imunes em um indivìduo e testes diagnósticos in vitro

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Publication number
BR0206364A
BR0206364A BR0206364-6A BR0206364A BR0206364A BR 0206364 A BR0206364 A BR 0206364A BR 0206364 A BR0206364 A BR 0206364A BR 0206364 A BR0206364 A BR 0206364A
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BR
Brazil
Prior art keywords
individual
methods
autoimmune diseases
diagnostic tests
vitro diagnostic
Prior art date
Application number
BR0206364-6A
Other languages
English (en)
Inventor
Jacques F Banchereau
Anna Karolina Palucka
Patrick Blanco
Original Assignee
Baylor Res Inst
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22989575&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0206364(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Baylor Res Inst filed Critical Baylor Res Inst
Publication of BR0206364A publication Critical patent/BR0206364A/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/249—Interferons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6866—Interferon
    • A—HUMAN NECESSITIES
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
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Abstract

"MéTODOS PARA TRATAR DOENçAS AUTOIMUNES EM UM INDIVìDUO E TESTES DIAGNóSTICOS IN VITRO". A presente invenção fornece um método para tratar uma doença auto-imune em um indivíduo por meio da administração de um antagonista de interferon e um antagonista de ligando de FIt3 (FIt3L). A invenção também fornece composições contendo um ou mais antagonistas de interferon, e um ou mais antagonistas de FIt3L, um teste in vitro para determinar o risco de um indivíduo para desenvolver uma doença auto-imune, e kits para aplicação, com o teste.
BR0206364-6A 2001-01-09 2002-01-08 Métodos para tratar doenças auto-imunes em um indivìduo e testes diagnósticos in vitro BR0206364A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26054101P 2001-01-09 2001-01-09
PCT/US2002/000343 WO2002067760A2 (en) 2001-01-09 2002-01-08 Methods for treating autoimmune diseases in a subject and in vitro diagnostic assays

Publications (1)

Publication Number Publication Date
BR0206364A true BR0206364A (pt) 2005-08-16

Family

ID=22989575

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0206364-6A BR0206364A (pt) 2001-01-09 2002-01-08 Métodos para tratar doenças auto-imunes em um indivìduo e testes diagnósticos in vitro

Country Status (15)

Country Link
US (3) US7544357B2 (pt)
EP (2) EP2236156A3 (pt)
JP (2) JP4394350B2 (pt)
KR (1) KR100951409B1 (pt)
CN (2) CN100536919C (pt)
AT (1) ATE502648T1 (pt)
AU (1) AU2002246955B2 (pt)
BR (1) BR0206364A (pt)
CA (1) CA2433806C (pt)
DE (1) DE60239522D1 (pt)
DK (1) DK1351707T3 (pt)
ES (1) ES2363761T3 (pt)
HK (1) HK1061353A1 (pt)
MX (1) MXPA03006100A (pt)
WO (1) WO2002067760A2 (pt)

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US20040067232A1 (en) 2004-04-08
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ATE502648T1 (de) 2011-04-15
US20090263474A1 (en) 2009-10-22
EP1351707B1 (en) 2011-03-23
KR20030070100A (ko) 2003-08-27
DK1351707T3 (da) 2011-07-11
EP1351707A4 (en) 2004-12-15
JP4394350B2 (ja) 2010-01-06
HK1061353A1 (en) 2004-09-17
ES2363761T3 (es) 2011-08-16
CN101612402A (zh) 2009-12-30
CN1529617A (zh) 2004-09-15
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US7544357B2 (en) 2009-06-09
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WO2002067760A3 (en) 2003-03-13
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