BR0115396A - Ensaio de interação de plaquetas e leucócitos e reagentes para o mesmo - Google Patents

Ensaio de interação de plaquetas e leucócitos e reagentes para o mesmo

Info

Publication number
BR0115396A
BR0115396A BR0115396-0A BR0115396A BR0115396A BR 0115396 A BR0115396 A BR 0115396A BR 0115396 A BR0115396 A BR 0115396A BR 0115396 A BR0115396 A BR 0115396A
Authority
BR
Brazil
Prior art keywords
platelet
reagents
leukocyte interaction
interaction assay
leukocyte
Prior art date
Application number
BR0115396-0A
Other languages
English (en)
Inventor
Donald E Mahan
Michael W Stewart
Original Assignee
Pharmanetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmanetics Inc filed Critical Pharmanetics Inc
Publication of BR0115396A publication Critical patent/BR0115396A/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G01N33/567—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds utilising isolate of tissue or organ as binding agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/823—Immunogenic carrier or carrier per se

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

"ENSAIO DE INTERAçãO DE PLAQUETAS E LEUCóCITOS E REAGENTES PARA O MESMO". A presente invenção refere-se a um método para ensaio de interação de plaquetas e leucócitos e reagente para o mesmo são fornecidos usando a presença de um estímulo de fase sólida, tal como partículas magnéticas ou não-magnéticas ou misturas das mesmas, tendo ligados à superfície do mesmo um ou mais ligantes que interagem diretamente com plaquetas, leucócitos ou ambos, para fornecer uma avaliação rápida e confiável do ponto de tratamento da interação de plaquetas e leucócitos.
BR0115396-0A 2000-11-15 2001-11-15 Ensaio de interação de plaquetas e leucócitos e reagentes para o mesmo BR0115396A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/712,165 US6586259B1 (en) 1999-11-15 2000-11-15 Platelet/leukocyte interaction assay and reagent therefor
PCT/US2001/042946 WO2002039949A2 (en) 2000-11-15 2001-11-15 Platelet/leukocyte interaction assay and reagent therefor

Publications (1)

Publication Number Publication Date
BR0115396A true BR0115396A (pt) 2004-02-03

Family

ID=24860995

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0115396-0A BR0115396A (pt) 2000-11-15 2001-11-15 Ensaio de interação de plaquetas e leucócitos e reagentes para o mesmo

Country Status (9)

Country Link
US (1) US6586259B1 (pt)
EP (1) EP1334363A2 (pt)
JP (1) JP2004537029A (pt)
KR (1) KR20030067686A (pt)
AU (1) AU2002233923A1 (pt)
BR (1) BR0115396A (pt)
CA (1) CA2428109A1 (pt)
MX (1) MXPA03004287A (pt)
WO (1) WO2002039949A2 (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020072078A1 (en) * 1999-04-28 2002-06-13 Development Center For Biotechnology, A Taiwan Corporation Rapid test for cell surface antigen
GB0015923D0 (en) * 2000-06-30 2000-08-23 Astrazeneca Ab Methods
WO2002010771A1 (en) * 2000-08-01 2002-02-07 Carepoint Diagnostics, Inc. Analysis of biological samples for platelet activation or coagulation activation markers using microparticules
DE10122806A1 (de) * 2001-05-10 2002-11-14 Holger Kiesewetter Verfahren zum Nachweis von Blutzell-Antigenen und gegen diese gerichtete Antikörper
US8697029B2 (en) * 2002-04-18 2014-04-15 The Regents Of The University Of Michigan Modulated physical and chemical sensors
US6852547B2 (en) * 2002-08-01 2005-02-08 Arizona Board Of Regents Dynamically formed rotors for lock-in amplifier detection
WO2004024026A2 (en) * 2002-09-10 2004-03-25 Ericson Daniel G Method and device for monitoring platelet function
US7439069B2 (en) * 2004-02-27 2008-10-21 Nippoldt Douglas D Blood coagulation test cartridge, system, and method
US7422905B2 (en) * 2004-02-27 2008-09-09 Medtronic, Inc. Blood coagulation test cartridge, system, and method
US7399637B2 (en) * 2004-04-19 2008-07-15 Medtronic, Inc. Blood coagulation test cartridge, system, and method
US20060269978A1 (en) * 2005-04-25 2006-11-30 Haworth William S Method and device for monitoring platelet function
AU2006323245B2 (en) * 2005-12-05 2011-03-03 Astrazeneca Ab New process for the preparation of esomeprazole non-salt form
WO2007079149A2 (en) 2005-12-28 2007-07-12 The General Hospital Corporation Blood cell sorting methods and systems
WO2008070324A2 (en) * 2006-10-25 2008-06-12 Placor, Inc. Methods and devices for monitoring platelet function
US9068977B2 (en) * 2007-03-09 2015-06-30 The Regents Of The University Of Michigan Non-linear rotation rates of remotely driven particles and uses thereof
US20110177592A1 (en) * 2008-07-11 2011-07-21 Faustman Denise L Magnetic apparatus for blood separation
US20110195872A1 (en) * 2010-02-10 2011-08-11 Richard Selinfreund Devices and systems for biomarker detection
WO2011127467A1 (en) * 2010-04-09 2011-10-13 Companion Diagnostics, Inc. Devices, systems, and methods for biomarker stabilization
US8846331B2 (en) 2010-08-27 2014-09-30 The Regents Of The University Of Michigan Asynchronous magnetic bead rotation sensing systems and methods
WO2012142179A2 (en) 2011-04-11 2012-10-18 The Regents Of The University Of Michigan Magnetically induced microspinning for super-detection and super-characterization of biomarkers and live cells
CA2908622A1 (en) 2012-04-18 2013-10-24 Hemoshear, Llc In vitro model for pathological or physiologic conditions
US9797817B2 (en) 2012-05-03 2017-10-24 The Regents Of The University Of Michigan Multi-mode separation for target detection
WO2015061372A1 (en) 2013-10-21 2015-04-30 Hemoshear, Llc In vitro model for a tumor microenvironment
US10823743B1 (en) * 2013-10-28 2020-11-03 Ifirst Medical Technologies, Inc. Methods of measuring coagulation of a biological sample
US9983110B2 (en) 2013-11-04 2018-05-29 The Regents Of The University Of Michigan Asynchronous magnetic bead rotation (AMBR) microviscometer for analysis of analytes
US20210181085A1 (en) * 2017-10-26 2021-06-17 Essenlix Corporation Rapid measurement of platelets
WO2019084515A1 (en) * 2017-10-26 2019-05-02 Essenlix Corporation DEVICES AND METHODS FOR COLORING TISSUES AND CELLS
KR102150803B1 (ko) 2019-10-29 2020-09-02 (주)바이오액츠 전혈분석을 위한 신규 형광 화합물 및 이의 제조방법
KR20220076995A (ko) * 2020-12-01 2022-06-08 재단법인대구경북과학기술원 세포, 미세입자 동시 분리 장치 및 그 방법

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2467301A (en) * 1945-07-23 1949-04-12 Sperry Prod Inc Supersonic inspection for flaws lying near the surface of apart
US4115535A (en) * 1977-06-22 1978-09-19 General Electric Company Diagnostic method employing a mixture of normally separable protein-coated particles
US5110727A (en) * 1987-04-03 1992-05-05 Cardiovascular Diagnostics, Inc. Method for performing coagulation assays accurately, rapidly and simply, using dry chemical reagents and paramagnetic particles
US5145784A (en) * 1988-05-04 1992-09-08 Cambridge Biotech Corporation Double capture assay method employing a capillary flow device
US5340719A (en) * 1990-11-23 1994-08-23 Corporation Coulter Method and apparatus for optically screening microscopic cells
AU671816B2 (en) * 1992-02-08 1996-09-12 Genera Technologies Limited Methods of analysis
US5427913A (en) * 1992-12-03 1995-06-27 Alberta Cancer Board Methods for determining platelet function
CA2156174A1 (en) * 1993-02-17 1994-09-01 Bruce Oberhardt Dry chemistry cascade immunoassay and affinity assay
US5670329A (en) * 1993-05-28 1997-09-23 Cardiovascular Diagnostics, Inc. Method and analytical system for performing fibrinogen assays accurately, rapidly and simply using a rotating magnetic field
US5503982A (en) * 1993-09-30 1996-04-02 Research Corporation Technologies, Inc. Detection of an acute myocardial infarction in a patient
US5763199A (en) * 1994-09-29 1998-06-09 Mount Sinai School Of Medicine Of The City University Of New York Platelet blockade assay

Also Published As

Publication number Publication date
JP2004537029A (ja) 2004-12-09
AU2002233923A1 (en) 2002-05-27
CA2428109A1 (en) 2002-05-23
WO2002039949A9 (en) 2003-02-06
EP1334363A2 (en) 2003-08-13
WO2002039949A3 (en) 2002-07-18
WO2002039949A2 (en) 2002-05-23
KR20030067686A (ko) 2003-08-14
US6586259B1 (en) 2003-07-01
MXPA03004287A (es) 2003-08-19

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]