BR0113478A - Mecanismo especìfico para inibição de adesão de plaqueta a colágeno - Google Patents
Mecanismo especìfico para inibição de adesão de plaqueta a colágenoInfo
- Publication number
- BR0113478A BR0113478A BR0113478-7A BR0113478A BR0113478A BR 0113478 A BR0113478 A BR 0113478A BR 0113478 A BR0113478 A BR 0113478A BR 0113478 A BR0113478 A BR 0113478A
- Authority
- BR
- Brazil
- Prior art keywords
- inhibition
- collagen
- platelet adhesion
- saratin
- specific mechanism
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1767—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M2025/0057—Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Peptides Or Proteins (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
"MECANISMO ESPECìFICO PARA INIBIçãO DE ADESãO DE PLAQUETA A COLáGENO". A invensão refere-se ao uso do polipeptídeo Saratin para a fabricação de um medicamento tendo a capacidade de diminuir significantemente adesão de plaquetas e acumulação de plaquetas após danos vasculares ou endarterectomia. A invenção ainda refere-se a um novo uso médico de Saratin como um inibidor de trombose e hiperplasia intimal, em que o dito polipeptídeo pode ser usado localmente como um agente tópico ou como um revestimento, ou de outro modo incorporado ou associado com dispositivos médicos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00118542 | 2000-08-25 | ||
PCT/EP2001/009746 WO2002015919A2 (en) | 2000-08-25 | 2001-08-23 | Saratin for inhibiting platelet adhesion to collagen |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0113478A true BR0113478A (pt) | 2003-07-15 |
Family
ID=8169664
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0113478-7A BR0113478A (pt) | 2000-08-25 | 2001-08-23 | Mecanismo especìfico para inibição de adesão de plaqueta a colágeno |
Country Status (27)
Country | Link |
---|---|
US (2) | US6881722B2 (pt) |
EP (1) | EP1311284B1 (pt) |
JP (1) | JP4988131B2 (pt) |
KR (1) | KR100794277B1 (pt) |
CN (1) | CN1224421C (pt) |
AR (1) | AR030492A1 (pt) |
AT (1) | ATE285246T1 (pt) |
AU (2) | AU2001295506B2 (pt) |
BR (1) | BR0113478A (pt) |
CA (1) | CA2419385C (pt) |
CZ (1) | CZ302353B6 (pt) |
DE (1) | DE60107962T2 (pt) |
DK (1) | DK1311284T3 (pt) |
EC (1) | ECSP034485A (pt) |
ES (1) | ES2234896T3 (pt) |
HK (1) | HK1059736A1 (pt) |
HU (1) | HU229367B1 (pt) |
MX (1) | MXPA03001604A (pt) |
MY (1) | MY128992A (pt) |
NO (1) | NO331326B1 (pt) |
PT (1) | PT1311284E (pt) |
RU (1) | RU2302880C2 (pt) |
SI (1) | SI1311284T1 (pt) |
SK (1) | SK287829B6 (pt) |
UA (1) | UA77402C2 (pt) |
WO (1) | WO2002015919A2 (pt) |
ZA (1) | ZA200302296B (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4805461B2 (ja) * | 1999-03-18 | 2011-11-02 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 血小板接着の阻止用タンパク質 |
JP2006517789A (ja) | 2003-01-10 | 2006-08-03 | アブリンクス エン.ヴェー. | 治療用ポリペプチド、その相同物、その断片、および血小板媒介凝集の調節での使用 |
US20110034396A1 (en) * | 2005-09-28 | 2011-02-10 | Biovascular, Inc. | Methods and compositions for inhibiting cell migration and treatment of inflammatory conditions |
WO2007038749A2 (en) * | 2005-09-28 | 2007-04-05 | Biovascular, Inc. | Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation |
US20080069774A1 (en) * | 2005-11-17 | 2008-03-20 | Lance Liotta | Proteomic antisense molecular shield and targeting |
WO2020049177A1 (en) * | 2018-09-06 | 2020-03-12 | Biomodics Aps | A medical tubular device |
CN117229423B (zh) * | 2023-11-10 | 2024-02-06 | 北京科技大学 | 一种用于结合胶原的多肽纳米材料及其制备方法和应用 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3947401A (en) * | 1971-10-05 | 1976-03-30 | Union Optics Corporation | Hydrogels of unsaturated ester copolymers |
US5705355A (en) * | 1984-03-27 | 1998-01-06 | Transgene, S.A. | Hirudin, pharmaceutical compositions comprising it and their use |
US4898734A (en) * | 1988-02-29 | 1990-02-06 | Massachusetts Institute Of Technology | Polymer composite for controlled release or membrane formation |
IL86857A (en) * | 1988-06-24 | 1994-04-12 | Yissum Res Dev Co | Platelet-aggregating inhibitory agents from leech saliva and pharmaceutical preparations containing the same |
US5304121A (en) * | 1990-12-28 | 1994-04-19 | Boston Scientific Corporation | Drug delivery system making use of a hydrogel polymer coating |
CA2052486A1 (en) * | 1990-10-09 | 1992-04-10 | Thomas M. Connolly | Protein for inhibiting collagen-stimulated platelet aggregation |
GB9022040D0 (en) | 1990-10-10 | 1990-11-21 | Biopharm Ltd | Platelet adhesion inhibitor |
US5179082A (en) * | 1990-11-13 | 1993-01-12 | Merck & Co., Inc. | Method for blocking platelet adhesion to collagen |
DE4136513A1 (de) | 1991-11-06 | 1993-05-13 | Basf Ag | Neues thrombininhibitorisches protein aus raubwanzen |
AU680929B2 (en) | 1993-07-01 | 1997-08-14 | Merck Patent Gmbh | Inhibitor of collagen-stimulated platelet aggregation |
DE69434598T3 (de) * | 1993-07-29 | 2010-07-29 | The United States Of America Represented By The Secretary, Department Of Health And Human Services | Verwendung von Paclitaxel und seinen Derivaten zur Herstellung eines Medikaments für die Behandlung von Restenose |
US5532287A (en) * | 1994-05-04 | 1996-07-02 | Ciba-Geigy Corporation | Radiation cured drug release controlling membrane |
US6246715B1 (en) * | 1998-06-26 | 2001-06-12 | Samsung Electronics Co., Ltd. | Data transmitter and receiver of a DS-CDMA communication system |
US5843172A (en) * | 1997-04-15 | 1998-12-01 | Advanced Cardiovascular Systems, Inc. | Porous medicated stent |
AU772460B2 (en) * | 1998-10-16 | 2004-04-29 | Immunex Corporation | Inhibitors of platelet activation and recruitment |
IT1304135B1 (it) * | 1998-11-26 | 2001-03-07 | Magneti Marelli Spa | Metodo di controllo dell' iniezione e dell' accensione in un motoreendotermico ad iniezione diretta per accelerare il riscaldamento del |
KR20010102130A (ko) * | 1999-02-19 | 2001-11-15 | 리스 데브라 케이. | 지혈 및 면역기능에 사용하기 위한 억제제 |
JP4805461B2 (ja) * | 1999-03-18 | 2011-11-02 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 血小板接着の阻止用タンパク質 |
-
2001
- 2001-08-22 MY MYPI20013935A patent/MY128992A/en unknown
- 2001-08-23 HU HU0303747A patent/HU229367B1/hu not_active IP Right Cessation
- 2001-08-23 CN CNB018146600A patent/CN1224421C/zh not_active Expired - Fee Related
- 2001-08-23 DK DK01976139T patent/DK1311284T3/da active
- 2001-08-23 BR BR0113478-7A patent/BR0113478A/pt not_active Application Discontinuation
- 2001-08-23 SK SK313-2003A patent/SK287829B6/sk not_active IP Right Cessation
- 2001-08-23 CZ CZ20030720A patent/CZ302353B6/cs not_active IP Right Cessation
- 2001-08-23 WO PCT/EP2001/009746 patent/WO2002015919A2/en active IP Right Grant
- 2001-08-23 US US10/362,476 patent/US6881722B2/en not_active Expired - Fee Related
- 2001-08-23 DE DE60107962T patent/DE60107962T2/de not_active Expired - Lifetime
- 2001-08-23 PT PT01976139T patent/PT1311284E/pt unknown
- 2001-08-23 AU AU2001295506A patent/AU2001295506B2/en not_active Ceased
- 2001-08-23 SI SI200130310T patent/SI1311284T1/xx unknown
- 2001-08-23 AT AT01976139T patent/ATE285246T1/de active
- 2001-08-23 AU AU9550601A patent/AU9550601A/xx active Pending
- 2001-08-23 CA CA2419385A patent/CA2419385C/en not_active Expired - Fee Related
- 2001-08-23 KR KR1020037002188A patent/KR100794277B1/ko not_active IP Right Cessation
- 2001-08-23 EP EP01976139A patent/EP1311284B1/en not_active Expired - Lifetime
- 2001-08-23 UA UA2003032476A patent/UA77402C2/uk unknown
- 2001-08-23 MX MXPA03001604A patent/MXPA03001604A/es active IP Right Grant
- 2001-08-23 ES ES01976139T patent/ES2234896T3/es not_active Expired - Lifetime
- 2001-08-23 JP JP2002520840A patent/JP4988131B2/ja not_active Expired - Fee Related
- 2001-08-23 RU RU2003107919/15A patent/RU2302880C2/ru not_active IP Right Cessation
- 2001-08-27 AR ARP010104073A patent/AR030492A1/es not_active Application Discontinuation
-
2003
- 2003-02-21 EC EC2003004485A patent/ECSP034485A/es unknown
- 2003-02-24 NO NO20030841A patent/NO331326B1/no not_active IP Right Cessation
- 2003-03-24 ZA ZA200302296A patent/ZA200302296B/en unknown
-
2004
- 2004-04-14 HK HK04102595A patent/HK1059736A1/xx not_active IP Right Cessation
- 2004-12-21 US US11/016,854 patent/US7459438B2/en not_active Expired - Fee Related
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 11, 25 DA LPI |
|
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |