BR0113033A - Composições farmacêuticas e métodos para uso - Google Patents
Composições farmacêuticas e métodos para usoInfo
- Publication number
- BR0113033A BR0113033A BR0113033-1A BR0113033A BR0113033A BR 0113033 A BR0113033 A BR 0113033A BR 0113033 A BR0113033 A BR 0113033A BR 0113033 A BR0113033 A BR 0113033A
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical compositions
- methods
- conditions
- moiety
- incorporating compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
"COMPOSIçõES FARMACêUTICAS E MéTODOS PARA USO". A presente invenção refere-se a composições farmacêuticas incorporam compostos que são capazes de afetar receptores colinérgicos nicotínicos. Uma ampla variedade de condições e distúrbios, e particularmente condições e distúrbios associadas com disfunção dos sistemas nervosos central e autónomo podem ser tratadas usando-se composições farmacêuticas incorporando compostos onde um anel aromático está ligado em ponte com uma unidade etilênica ou acetilênica a uma porção aza bicíclica.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/633,156 US6624167B1 (en) | 2000-08-04 | 2000-08-04 | Pharmaceutical compositions and methods for use |
PCT/US2001/022170 WO2002012245A2 (en) | 2000-08-04 | 2001-07-13 | Azabicyclic derivatives and their therapeutic use |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0113033A true BR0113033A (pt) | 2003-07-15 |
Family
ID=24538497
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0113033-1A BR0113033A (pt) | 2000-08-04 | 2001-07-13 | Composições farmacêuticas e métodos para uso |
Country Status (14)
Country | Link |
---|---|
US (2) | US6624167B1 (pt) |
EP (1) | EP1305316A2 (pt) |
JP (1) | JP2004536019A (pt) |
CN (1) | CN1447811A (pt) |
AU (1) | AU2001276911A1 (pt) |
BR (1) | BR0113033A (pt) |
CA (1) | CA2417967A1 (pt) |
HU (1) | HUP0401225A3 (pt) |
IL (1) | IL153897A0 (pt) |
NO (1) | NO20030547L (pt) |
NZ (1) | NZ523728A (pt) |
PL (1) | PL363048A1 (pt) |
WO (1) | WO2002012245A2 (pt) |
ZA (1) | ZA200300571B (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1506205B1 (en) * | 2002-05-07 | 2008-07-16 | Neurosearch A/S | Novel azacyclic ethynyl derivatives |
WO2004009599A1 (en) * | 2002-07-19 | 2004-01-29 | Targacept, Inc. | Five-membered heteroaromatic olefinic azacyclic compounds, pharmaceutical compositions containing them and their use as inhibitors of ncotinic cholinergic receptors |
US7098331B2 (en) | 2003-03-05 | 2006-08-29 | Targacept, Inc. | Arylvinylazacycloalkane compounds and methods of preparation and use thereof |
US7235688B1 (en) | 2004-11-04 | 2007-06-26 | University Of Notre Dame Du Lac | Process for preparing histone deacetylase inhibitors and intermediates thereof |
US20070021612A1 (en) * | 2004-11-04 | 2007-01-25 | University Of Notre Dame Du Lac | Processes and compounds for preparing histone deacetylase inhibitors and intermediates thereof |
PE20061162A1 (es) * | 2004-12-06 | 2006-10-14 | Smithkline Beecham Corp | Compuestos derivados olefinicos de 8-azoniabiciclo[3.2.1]octanos |
US20090239901A1 (en) * | 2008-03-19 | 2009-09-24 | Merouane Bencherif | Method and compositions for treatment of cerebral malaria |
TW201031664A (en) | 2009-01-26 | 2010-09-01 | Targacept Inc | Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide |
CN102648202A (zh) | 2009-12-07 | 2012-08-22 | 塔加西普特公司 | 作为神经元烟碱乙酰胆碱受体配体的3,6-二氮杂双环[3.1.1]庚烷 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5817679A (en) | 1993-04-01 | 1998-10-06 | University Of Virginia | 7-Azabicyclo 2.2.1!-heptane and -heptene derivatives as cholinergic receptor ligands |
US6060473A (en) | 1993-04-01 | 2000-05-09 | Ucb S.A. - Dtb | 7-azabicyclo[2.2.1]-heptane and -heptene derivatives as cholinergic receptor ligands |
US5852041A (en) | 1993-04-07 | 1998-12-22 | Sibia Neurosciences, Inc. | Substituted pyridines useful as modulators of acethylcholine receptors |
JP3637973B2 (ja) | 1993-06-17 | 2005-04-13 | エーザイ株式会社 | アザビシクロヘプタン誘導体 |
US5510355A (en) | 1994-09-06 | 1996-04-23 | Bencherif; Merouane | Depolarizing skeletal muscle relaxants |
US5583140A (en) | 1995-05-17 | 1996-12-10 | Bencherif; Merouane | Pharmaceutical compositions for the treatment of central nervous system disorders |
US6022868A (en) | 1995-06-29 | 2000-02-08 | Novo Nordisk Als | Substituted azacyclic or azabicyclic compounds |
EP0853621A1 (en) | 1995-09-22 | 1998-07-22 | Novo Nordisk A/S | Novel substituted azacyclic or azabicyclic compounds |
US6100275A (en) | 1995-10-13 | 2000-08-08 | Neurosearch A/S | 8-azabicyclo[3.2.1.]oct-2-ene derivatives, their preparation and use |
CA2289570C (en) | 1997-05-30 | 2007-04-03 | Neurosearch A/S | 9-azabicyclo(3.3.1)non-2-ene and nonane derivatives as cholinergic ligands at nicotinic ach receptors |
US5952339A (en) | 1998-04-02 | 1999-09-14 | Bencherif; Merouane | Pharmaceutical compositions and methods of using nicotinic antagonists for treating a condition or disorder characterized by alteration in normal neurotransmitter release |
DE60038823D1 (de) | 1999-01-29 | 2008-06-19 | Abbott Lab | Diazabicycloderivate als Nikotin-Acetylcholin-Rezeptorliganden |
FR2791678B1 (fr) | 1999-03-30 | 2001-05-04 | Synthelabo | Derives de 1,4-diazabicyclo [3.2.2] nonane-4-carboxylates et -carboxamides, leur preparation et leur application en therapeutique |
WO2001032264A1 (en) | 1999-11-01 | 2001-05-10 | Targacept, Inc. | Aryl olefinic azacyclic, and aryl acetylenic azacyclic compounds, pharmaceutical compositions containing them and their use as inhibitors of nicotinic cholinergic receptors |
GB0000257D0 (en) | 2000-01-07 | 2000-03-01 | Univ Bristol | 9-Azabicyclo[4.2.1]non-2-ene derivatives as ligands for nicotinic acetylcholine receptors |
-
2000
- 2000-08-04 US US09/633,156 patent/US6624167B1/en not_active Expired - Fee Related
-
2001
- 2001-07-13 HU HU0401225A patent/HUP0401225A3/hu unknown
- 2001-07-13 EP EP01954684A patent/EP1305316A2/en not_active Ceased
- 2001-07-13 JP JP2002518220A patent/JP2004536019A/ja not_active Withdrawn
- 2001-07-13 CA CA002417967A patent/CA2417967A1/en not_active Abandoned
- 2001-07-13 PL PL01363048A patent/PL363048A1/xx not_active Application Discontinuation
- 2001-07-13 CN CN01813738A patent/CN1447811A/zh active Pending
- 2001-07-13 IL IL15389701A patent/IL153897A0/xx unknown
- 2001-07-13 BR BR0113033-1A patent/BR0113033A/pt not_active IP Right Cessation
- 2001-07-13 NZ NZ523728A patent/NZ523728A/en unknown
- 2001-07-13 WO PCT/US2001/022170 patent/WO2002012245A2/en active IP Right Grant
- 2001-07-13 AU AU2001276911A patent/AU2001276911A1/en not_active Abandoned
-
2003
- 2003-01-21 ZA ZA200300571A patent/ZA200300571B/en unknown
- 2003-02-04 NO NO20030547A patent/NO20030547L/no unknown
- 2003-09-23 US US10/668,692 patent/US7022706B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
PL363048A1 (en) | 2004-11-15 |
WO2002012245A3 (en) | 2002-06-13 |
EP1305316A2 (en) | 2003-05-02 |
ZA200300571B (en) | 2004-04-21 |
NO20030547D0 (no) | 2003-02-04 |
AU2001276911A1 (en) | 2002-02-18 |
US20040152723A1 (en) | 2004-08-05 |
IL153897A0 (en) | 2003-07-31 |
US7022706B2 (en) | 2006-04-04 |
NZ523728A (en) | 2004-09-24 |
HUP0401225A3 (en) | 2005-07-28 |
WO2002012245B1 (en) | 2003-03-20 |
US6624167B1 (en) | 2003-09-23 |
CN1447811A (zh) | 2003-10-08 |
WO2002012245A2 (en) | 2002-02-14 |
NO20030547L (no) | 2003-02-04 |
CA2417967A1 (en) | 2002-02-14 |
JP2004536019A (ja) | 2004-12-02 |
HUP0401225A2 (hu) | 2004-12-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA31521B1 (fr) | Dérivés de 2,3-dihydrobenzo[1,4] dioxin-2-ylméthyle utilisés en tant qu'antagonistes des alpha2c pour traiter des maladies des systèmes nerveux périphérique et central | |
ATE311184T1 (de) | 1-benzyl-3-(substituiertes-hetaryl)-kondensiert n pyrazol-derivaten zur behandlung von erkrankungen des herz-kreislaufsystems und des zentralnervensystems | |
EA200100589A1 (ru) | Азабициклоалканы как модуляторы ccr5 | |
EA200100588A1 (ru) | Пиперидины как модуляторы ccr5 | |
BR0213877A (pt) | Compostos orgânicos | |
BRPI0612141A2 (pt) | derivados de quinuclidina substituìdos com biciclo-heterociclos fundidos | |
BG100830A (en) | Naphthylamides as central nervous system agents | |
BR0016282A (pt) | Inibidores de caspase e usos destes | |
NO20042964L (no) | Spiroazasykliske forbindelser som monoaminreseptormodulatorer | |
NZ515529A (en) | Benzene derivatives, preparation method and pharmaceutical compositions containing same | |
EA200400466A1 (ru) | Производные пиперазина с антагонистической активностью к рецептору ccr1 | |
EA200100774A1 (ru) | Гетероциклические производные с функциональными группами (варианты), фармацевтическая композиция и комбинация, способ модулирования активности рецептора хемокина (варианты), способ профилактики инфицирования вич и лечения инфекции вич, замедления проявления спид и лечения спид, способ лечения воспалительных процессов | |
ATE425142T1 (de) | Inhibitoren von c-jun n-terminal kinasen (jnk) | |
BR0113033A (pt) | Composições farmacêuticas e métodos para uso | |
BRPI0417948A (pt) | derivados de quinuclidina substituìda por bicicloheterociclo fundido | |
HUP0103203A2 (hu) | Azaadamantánszármazékok és ezeket tartalmazó gyógyszerkészítmények | |
GT199800135A (es) | 2 - aminopiridinas con sustituyentes alcoxi ramificados. | |
RU94036745A (ru) | Производные галантамина и фармацевтическая композиция | |
BR0015401A (pt) | [(indol-3-il)-cicloalquil]-3-azetidinas substituìdas para o tratamento de distúrbios do sistema nervoso central | |
FI905957A (fi) | Foerfarande foer framstaellning av substituerade cyklohexener, som verkar pao det centrala nervsystemet. | |
AR013844A1 (es) | Compuestos derivados de 3-oxo-pirido[1,2-a] bencimidazol-4-carboxamida sustituidos en posicion 5 con alquilo que contiene heteroatomo,- y composiciones farmaceuticas que los comprenden. | |
BR0214324A (pt) | Formas diméricas e multiméricas de acilfosfinas, óxidos de acilfosfina e sulfetos de acilfosfina | |
BR0116762A (pt) | Análogos tacrolimus neurotróficos, métodos e uso dos mesmos | |
ATE271786T1 (de) | Dioxabicyclo 3.3.0 octan-derivate, z.b. sesamin etc., zur vorbeugung und erleichterung von allergiesymptomen | |
WO2002004442A3 (en) | Azabicyclic compounds as inhibitors of nicotinic cholinergic receptors |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A , 9A E 10 ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2144 DE 07/02/2012. |