BR0111390A - Composição e aplicador para liberação de substância tópica - Google Patents
Composição e aplicador para liberação de substância tópicaInfo
- Publication number
- BR0111390A BR0111390A BR0111390-9A BR0111390A BR0111390A BR 0111390 A BR0111390 A BR 0111390A BR 0111390 A BR0111390 A BR 0111390A BR 0111390 A BR0111390 A BR 0111390A
- Authority
- BR
- Brazil
- Prior art keywords
- composition
- applicator
- hydration
- substance release
- topical substance
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0014—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/008—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C08F220/20—Esters of polyhydric alcohols or phenols, e.g. 2-hydroxyethyl (meth)acrylate or glycerol mono-(meth)acrylate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Materials Engineering (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Dispersion Chemistry (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Obesity (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
Abstract
"COMPOSIçãO E APLICADOR PARA LIBERAçãO DE SUBSTâNCIA TóPICA". Uma composição de hidrogel polimerizado e um aplicador para hidratar ou desidratar uma superfície, particularmente uma superfície dermatológica, a qual ela é aplicada e um método para formar a composição. A composição compreende uma mistura de dois materiais polimerizáveis, um sistema de catalisador de redox e um meio de polimerização de duas partes. A percentagem em peso de cada elemento na composição pode ser variada dentro de faixas de percentagem estabelecidas. A faixa na qual a hidratação e desidratação ocorre pode ser alterada de forma controlada por variação de certos elementos da composição. O aplicador inclui uma seção central termoplástica e duas seções de reservatório cada uma tendo uma área de estocagem de reservatório para reter umidade e/ou medicamentos. A composição é unida mecanicamente em cada uma das seções de reservatório e então hidratada. O aplicador é projetado para inserção na boca de um humano depois de hidratação e é usado para tratar a xerostomia.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/580,679 US6592860B1 (en) | 2000-05-30 | 2000-05-30 | Composition and applicator for topical substance delivery |
PCT/US2001/015462 WO2001091682A1 (en) | 2000-05-30 | 2001-05-11 | Composition and applicator for topical substance delivery |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0111390A true BR0111390A (pt) | 2004-12-07 |
Family
ID=24322084
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0111390-9A BR0111390A (pt) | 2000-05-30 | 2001-05-11 | Composição e aplicador para liberação de substância tópica |
Country Status (8)
Country | Link |
---|---|
US (4) | US6592860B1 (pt) |
EP (1) | EP1299157A1 (pt) |
JP (1) | JP2004509844A (pt) |
AU (2) | AU2001261540B2 (pt) |
BR (1) | BR0111390A (pt) |
CA (1) | CA2410706C (pt) |
MX (1) | MXPA02011722A (pt) |
WO (1) | WO2001091682A1 (pt) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6592860B1 (en) * | 2000-05-30 | 2003-07-15 | Soluble Systems, Llc | Composition and applicator for topical substance delivery |
US6675613B2 (en) * | 2001-06-18 | 2004-01-13 | Wesley Scott Ashton | Tongue and mouth stud for dispensing a substance |
US7328706B2 (en) | 2002-05-06 | 2008-02-12 | Dynamic Mouth Devices Llc | Therapeutic and protective dental device useful as an intra-oral delivery system |
US20060058705A1 (en) * | 2004-08-26 | 2006-03-16 | Leonetti Joseph A | Geometrically shaped hydrogel standoffs for coupling high intensity focused ultrasound |
US7384626B2 (en) * | 2004-08-31 | 2008-06-10 | Triton Systems, Inc. | Functionalized dendritic polymers for the capture and neutralization of biological and chemical agents |
US20070048347A1 (en) * | 2005-08-26 | 2007-03-01 | Laura Bardach | Intra-oral device for treating obesity |
DE602006010656D1 (de) * | 2006-02-02 | 2010-01-07 | Euro Celtique Sa | Hydrogel für Wundbehandlung |
US11129690B2 (en) | 2006-03-28 | 2021-09-28 | Devicor Medical Products, Inc. | Method for making hydrogel markers |
US8939910B2 (en) | 2006-03-28 | 2015-01-27 | Devicor Medical Products, Inc. | Method for enhancing ultrasound visibility of hyperechoic materials |
US20170066162A9 (en) | 2006-03-28 | 2017-03-09 | Devicor Medical Products, Inc. | Method of Enhancing Ultrasound Visibility of Hyperechoic Materials |
AU2007269790A1 (en) * | 2006-06-30 | 2008-01-10 | Tyco Healthcare Group, Lp | Wound closure adhesive remover |
US8986253B2 (en) | 2008-01-25 | 2015-03-24 | Tandem Diabetes Care, Inc. | Two chamber pumps and related methods |
US8408421B2 (en) | 2008-09-16 | 2013-04-02 | Tandem Diabetes Care, Inc. | Flow regulating stopcocks and related methods |
WO2010033878A2 (en) | 2008-09-19 | 2010-03-25 | David Brown | Solute concentration measurement device and related methods |
US9250106B2 (en) | 2009-02-27 | 2016-02-02 | Tandem Diabetes Care, Inc. | Methods and devices for determination of flow reservoir volume |
WO2010099490A2 (en) | 2009-02-27 | 2010-09-02 | Tandem Diabetes Care, Inc. | Methods and devices for determination of flow reservoir volume |
US8758323B2 (en) | 2009-07-30 | 2014-06-24 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
BR112013001550A2 (pt) | 2010-07-21 | 2016-05-24 | 3M Innovative Properties Co | composições, dispositivos e métodos de adesivos trandérmicos |
US9821159B2 (en) | 2010-11-16 | 2017-11-21 | The Board Of Trustees Of The Leland Stanford Junior University | Stimulation devices and methods |
CN103313754B (zh) | 2010-11-16 | 2015-09-30 | 小利兰·斯坦福大学理事会 | 用于治疗干眼的***和方法 |
US9180242B2 (en) | 2012-05-17 | 2015-11-10 | Tandem Diabetes Care, Inc. | Methods and devices for multiple fluid transfer |
US9717627B2 (en) | 2013-03-12 | 2017-08-01 | Oculeve, Inc. | Implant delivery devices, systems, and methods |
US9173998B2 (en) | 2013-03-14 | 2015-11-03 | Tandem Diabetes Care, Inc. | System and method for detecting occlusions in an infusion pump |
US9603995B2 (en) | 2013-03-15 | 2017-03-28 | Tandem Diabetes Care. Inc. | Device and method for setting therapeutic parameters for an infusion device |
NZ704579A (en) | 2013-04-19 | 2018-10-26 | Oculeve Inc | Nasal stimulation devices and methods |
CN106470673B (zh) | 2014-02-25 | 2020-01-31 | 奥库利维公司 | 用于鼻泪刺激的聚合物制剂 |
JP6643313B2 (ja) | 2014-07-25 | 2020-02-12 | オキュリーブ, インコーポレイテッド | ドライアイを治療するための刺激パターン |
US10207108B2 (en) | 2014-10-22 | 2019-02-19 | Oculeve, Inc. | Implantable nasal stimulator systems and methods |
WO2016065211A1 (en) | 2014-10-22 | 2016-04-28 | Oculeve, Inc. | Contact lens for increasing tear production |
ES2809599T3 (es) | 2014-10-22 | 2021-03-04 | Oculeve Inc | Dispositivos de estimulación para tratar la sequedad ocular |
US10575976B2 (en) | 2015-04-30 | 2020-03-03 | Dynamic Mouth Devices, L.L.C. | Method and apparatus for weight management utilizing an intra-oral device |
US10426958B2 (en) | 2015-12-04 | 2019-10-01 | Oculeve, Inc. | Intranasal stimulation for enhanced release of ocular mucins and other tear proteins |
US10252048B2 (en) | 2016-02-19 | 2019-04-09 | Oculeve, Inc. | Nasal stimulation for rhinitis, nasal congestion, and ocular allergies |
CA3022683A1 (en) | 2016-05-02 | 2017-11-09 | Oculeve, Inc. | Intranasal stimulation for treatment of meibomian gland disease and blepharitis |
JP2020500609A (ja) | 2016-12-02 | 2020-01-16 | オキュリーブ, インコーポレイテッド | ドライアイ予測及び治療勧告のための装置及び方法 |
CN110643055A (zh) * | 2019-10-08 | 2020-01-03 | 宁波瑞瑧生物科技有限公司 | 水凝胶及其制备方法、生物膜固定装置和应用 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3862452A (en) * | 1966-05-04 | 1975-01-28 | Ceskoslovenska Akademie Ved | Hydrogel substitutes for tubular somatic organs |
JPS6024807B2 (ja) * | 1979-02-19 | 1985-06-14 | 昭和電工株式会社 | 高吸水性ヒドロゲルの製造方法 |
US4680336A (en) | 1984-11-21 | 1987-07-14 | Vistakon, Inc. | Method of forming shaped hydrogel articles |
US4889530A (en) * | 1986-10-06 | 1989-12-26 | University Of Akron | Wound dressing containing acrylate or methacrylate hydrogel polymer |
US4900552A (en) * | 1988-03-30 | 1990-02-13 | Watson Laboratories, Inc. | Mucoadhesive buccal dosage forms |
CA2072148C (en) * | 1989-10-31 | 2002-04-23 | Joseph R. Robinson | Tissue moisturizing composition and method |
WO1991015260A1 (en) * | 1990-03-30 | 1991-10-17 | Alza Corporation | Device and method for iontophoretic drug delivery |
US5695456A (en) * | 1992-04-02 | 1997-12-09 | Ndm, Inc. | Wound packing and package therefor |
US5614223A (en) | 1992-05-04 | 1997-03-25 | Digestive Care Inc. | Intraoral medicament-releasing device |
DK0604103T3 (da) * | 1992-12-15 | 1999-09-27 | Johnson & Johnson Consumer | Hydrogellaminat, forbindinger og materialer samt fremgangsmåder til fremstilling deraf |
US5457140A (en) | 1993-07-22 | 1995-10-10 | Johnson & Johnson Vision Products, Inc. | Method of forming shaped hydrogel articles including contact lenses using inert, displaceable diluents |
US6271278B1 (en) * | 1997-05-13 | 2001-08-07 | Purdue Research Foundation | Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties |
US6103266A (en) * | 1998-04-22 | 2000-08-15 | Tapolsky; Gilles H. | Pharmaceutical gel preparation applicable to mucosal surfaces and body tissues |
IL138990A0 (en) * | 1999-02-12 | 2001-11-25 | Biostream Inc | Matrices for drug delivery and methods for making and using the same |
US6485708B1 (en) * | 1999-05-13 | 2002-11-26 | Church & Dwight Co. Inc. | Products and methods for the remineralization and prevention of demineralization of teeth |
KR100721752B1 (ko) * | 2000-01-24 | 2007-05-25 | 쿠라레 메디카루 가부시키가이샤 | 수팽윤성 고분자 겔 및 그 제조법 |
US6592860B1 (en) * | 2000-05-30 | 2003-07-15 | Soluble Systems, Llc | Composition and applicator for topical substance delivery |
US6485709B2 (en) * | 2001-01-23 | 2002-11-26 | Addent Inc. | Dental bleaching gel composition, activator system and method for activating a dental bleaching gel |
-
2000
- 2000-05-30 US US09/580,679 patent/US6592860B1/en not_active Expired - Lifetime
-
2001
- 2001-05-11 JP JP2001587699A patent/JP2004509844A/ja active Pending
- 2001-05-11 AU AU2001261540A patent/AU2001261540B2/en not_active Ceased
- 2001-05-11 WO PCT/US2001/015462 patent/WO2001091682A1/en active IP Right Grant
- 2001-05-11 MX MXPA02011722A patent/MXPA02011722A/es unknown
- 2001-05-11 CA CA002410706A patent/CA2410706C/en not_active Expired - Fee Related
- 2001-05-11 BR BR0111390-9A patent/BR0111390A/pt not_active Application Discontinuation
- 2001-05-11 AU AU6154001A patent/AU6154001A/xx active Pending
- 2001-05-11 EP EP01935443A patent/EP1299157A1/en not_active Withdrawn
-
2003
- 2003-02-24 US US10/372,740 patent/US20030165569A1/en not_active Abandoned
-
2005
- 2005-05-23 US US11/135,184 patent/US20050214334A1/en not_active Abandoned
-
2007
- 2007-04-06 US US11/697,491 patent/US20070237825A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2001091682A8 (en) | 2002-07-04 |
JP2004509844A (ja) | 2004-04-02 |
US6592860B1 (en) | 2003-07-15 |
AU2001261540B2 (en) | 2004-10-28 |
CA2410706C (en) | 2009-06-09 |
US20070237825A1 (en) | 2007-10-11 |
US20030165569A1 (en) | 2003-09-04 |
WO2001091682A1 (en) | 2001-12-06 |
CA2410706A1 (en) | 2001-12-06 |
AU6154001A (en) | 2001-12-11 |
MXPA02011722A (es) | 2003-10-14 |
EP1299157A1 (en) | 2003-04-09 |
US20050214334A1 (en) | 2005-09-29 |
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