BR0109169A - Microcápsulas compreendendo cianoacrilatos de polialquila - Google Patents
Microcápsulas compreendendo cianoacrilatos de polialquilaInfo
- Publication number
- BR0109169A BR0109169A BR0109169-7A BR0109169A BR0109169A BR 0109169 A BR0109169 A BR 0109169A BR 0109169 A BR0109169 A BR 0109169A BR 0109169 A BR0109169 A BR 0109169A
- Authority
- BR
- Brazil
- Prior art keywords
- microcapsules
- polyalkyl
- cyanoacrylates
- gas
- polyalkyl cyanoacrylates
- Prior art date
Links
- 239000003094 microcapsule Substances 0.000 title abstract 3
- 229920000771 poly (alkylcyanoacrylate) Polymers 0.000 title abstract 3
- 229920001651 Cyanoacrylate Polymers 0.000 abstract 1
- -1 alkyl cyanoacrylates Chemical class 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
- 238000002604 ultrasonography Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Radiology & Medical Imaging (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Acoustics & Sound (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Polymerisation Methods In General (AREA)
Abstract
"MICROCáPSULAS COMPREENDENDO CIANOACRILATOS DE POLIALQUILA". A invenção relaciona-se às microcápsulas enchidas com gás que consistem em cianoacrilatos de polialquila, que são produzidos por copolimerização de um ou mais cianoacrilatos de alquila com um monómero funcional e/ou por hidrólise parcial da cadeia lateral de um cianoacrilato de polialquila, bem como a um processo para a produção de microcápsulas enchidas com gás e ao seu uso para a diagnose por ultra-som.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10013850A DE10013850A1 (de) | 2000-03-15 | 2000-03-15 | Gasgefüllte Mikrokapseln enthaltend funktionalisiertes Polyalkylcyanacrylat, sowie Verfahren zu deren Herstellung |
PCT/EP2001/002802 WO2001068150A1 (en) | 2000-03-15 | 2001-03-13 | Microcapsules comprising functionalised polyalkylcyanoacrylates |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0109169A true BR0109169A (pt) | 2002-12-10 |
Family
ID=7635680
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0109169-7A BR0109169A (pt) | 2000-03-15 | 2001-03-13 | Microcápsulas compreendendo cianoacrilatos de polialquila |
Country Status (22)
Country | Link |
---|---|
US (1) | US20030157023A1 (pt) |
EP (1) | EP1267947A1 (pt) |
JP (1) | JP2004500397A (pt) |
KR (1) | KR20030041859A (pt) |
CN (1) | CN1424919A (pt) |
AU (1) | AU5218901A (pt) |
BG (1) | BG107085A (pt) |
BR (1) | BR0109169A (pt) |
CA (1) | CA2400906A1 (pt) |
CZ (1) | CZ20023101A3 (pt) |
DE (1) | DE10013850A1 (pt) |
EA (1) | EA200200881A1 (pt) |
EE (1) | EE200200524A (pt) |
HU (1) | HUP0300355A2 (pt) |
IL (1) | IL151472A0 (pt) |
MX (1) | MXPA02008874A (pt) |
NO (1) | NO20024382L (pt) |
PL (1) | PL364159A1 (pt) |
SK (1) | SK13202002A3 (pt) |
WO (1) | WO2001068150A1 (pt) |
YU (1) | YU68902A (pt) |
ZA (1) | ZA200208277B (pt) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA05007730A (es) | 2003-02-04 | 2006-01-31 | Bracco Int Bv | Agentes de contraste para ultrasonido y proceso para la preparacion de los mismos. |
US9750821B2 (en) | 2003-12-22 | 2017-09-05 | Bracco Suisse S.A. | Gas-filled microvesicle assembly for contrast imaging |
WO2005070472A2 (en) | 2004-01-20 | 2005-08-04 | Sunnybrook And Women's College Health Sciences Centre, | High frequency ultrasound imaging using contrast agents |
CN101005858A (zh) * | 2004-08-18 | 2007-07-25 | 伯拉考开发股份有限公司 | 用于反差成像的充气微泡组合物 |
US8275449B2 (en) | 2005-11-11 | 2012-09-25 | Visualsonics Inc. | Overlay image contrast enhancement |
EP2474327A1 (en) | 2011-01-07 | 2012-07-11 | RWTH Aachen | Microdosing of ultrasound contrast agents |
EP2545908A1 (en) | 2011-07-11 | 2013-01-16 | RWTH Aachen | Medium for microbubbles or microparticles and preparation thereof |
UA115789C2 (uk) * | 2012-09-05 | 2017-12-26 | Трейкон Фармасутікалз, Інк. | Композиція антитіла до cd105 та її застосування |
US20160030603A1 (en) | 2013-03-15 | 2016-02-04 | Westfaelische Wilhelms-Universitaet Muenster | Detection of acute renal allograft rejection |
CN104107440A (zh) * | 2013-04-17 | 2014-10-22 | 刘哲 | 一种新型粒径可控的聚酯硬壳微泡体系的制备工艺 |
US10898581B2 (en) * | 2014-01-16 | 2021-01-26 | The Brigham And Women's Hospital, Inc. | Targeted delivery of immunoregulatory drugs |
JP6818677B2 (ja) | 2014-09-25 | 2021-01-20 | プレミア デンタル プロダクツ カンパニー | 結合性マイクロカプセル及び表面官能化フィラー |
WO2017207325A1 (de) | 2016-06-02 | 2017-12-07 | Evonik Degussa Gmbh | Verfahren zur herstellung eines elektrodenmaterials |
JP7369711B2 (ja) * | 2018-07-25 | 2023-10-26 | フイルメニツヒ ソシエテ アノニム | マイクロカプセルの製造方法 |
CN110498877B (zh) * | 2019-09-05 | 2022-11-08 | 大连合元医疗器械有限公司 | 聚(2-羧基丙烯酸)及其制备方法和应用 |
WO2021043004A1 (zh) * | 2019-09-05 | 2021-03-11 | 大连合元医疗器械有限公司 | 聚[α-氰基丙烯酸酯]水解产物及其制备方法和应用 |
CN115093497A (zh) * | 2019-09-05 | 2022-09-23 | 大连合元医疗器械有限公司 | 聚(2-氰基丙烯酸)及其在栓塞微球的应用 |
DE102021105820A1 (de) | 2021-03-10 | 2022-09-15 | Rheinisch-Westfälische Technische Hochschule (Rwth) Aachen | Theranostische polymere Mikropartikel für die Behandlung von vaskulären Erkrankungen durch ultraschallvermittelte Wirkstoffabgabe |
WO2023156806A1 (en) * | 2022-02-21 | 2023-08-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Method for manufacturing bubbles having a polymeric shell using sound waves for generating the bubbles |
CN116731301B (zh) * | 2023-06-30 | 2024-03-19 | 珠海市凯拓塑料制品有限公司 | 一种生物基防刮花吸塑托盘及其制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5425366A (en) * | 1988-02-05 | 1995-06-20 | Schering Aktiengesellschaft | Ultrasonic contrast agents for color Doppler imaging |
DE4219724A1 (de) * | 1992-06-13 | 1993-12-16 | Schering Ag | Verwendung von Mikrokapseln als Kontrastmittel für die Farbdoppler-Sonographie |
AU636481B2 (en) * | 1990-05-18 | 1993-04-29 | Bracco International B.V. | Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography |
GB9106673D0 (en) * | 1991-03-28 | 1991-05-15 | Hafslund Nycomed As | Improvements in or relating to contrast agents |
DE4219723A1 (de) * | 1992-06-13 | 1993-12-16 | Schering Ag | Mikropartikel, Verfahren zu deren Herstellung, sowie die Verwendung dieser in der Diagnostik |
DE4232755A1 (de) * | 1992-09-26 | 1994-03-31 | Schering Ag | Mikropartikelpräparationen aus biologisch abbaubaren Mischpolymeren |
US6383470B1 (en) * | 1992-09-26 | 2002-05-07 | Thomas Fritzsch | Microparticle preparations made of biodegradable copolymers |
-
2000
- 2000-03-15 DE DE10013850A patent/DE10013850A1/de not_active Withdrawn
-
2001
- 2001-03-13 IL IL15147201A patent/IL151472A0/xx unknown
- 2001-03-13 CZ CZ20023101A patent/CZ20023101A3/cs unknown
- 2001-03-13 WO PCT/EP2001/002802 patent/WO2001068150A1/en not_active Application Discontinuation
- 2001-03-13 SK SK1320-2002A patent/SK13202002A3/sk unknown
- 2001-03-13 CN CN01806535A patent/CN1424919A/zh active Pending
- 2001-03-13 AU AU52189/01A patent/AU5218901A/en not_active Abandoned
- 2001-03-13 YU YU68902A patent/YU68902A/sh unknown
- 2001-03-13 PL PL01364159A patent/PL364159A1/xx not_active Application Discontinuation
- 2001-03-13 EE EEP200200524A patent/EE200200524A/xx unknown
- 2001-03-13 JP JP2001566712A patent/JP2004500397A/ja active Pending
- 2001-03-13 KR KR1020027012119A patent/KR20030041859A/ko not_active Application Discontinuation
- 2001-03-13 EP EP01925434A patent/EP1267947A1/en not_active Withdrawn
- 2001-03-13 CA CA002400906A patent/CA2400906A1/en not_active Abandoned
- 2001-03-13 MX MXPA02008874A patent/MXPA02008874A/es unknown
- 2001-03-13 US US10/221,727 patent/US20030157023A1/en not_active Abandoned
- 2001-03-13 EA EA200200881A patent/EA200200881A1/ru unknown
- 2001-03-13 BR BR0109169-7A patent/BR0109169A/pt not_active Application Discontinuation
- 2001-03-13 HU HU0300355A patent/HUP0300355A2/hu unknown
-
2002
- 2002-09-11 BG BG107085A patent/BG107085A/bg unknown
- 2002-09-13 NO NO20024382A patent/NO20024382L/no not_active Application Discontinuation
- 2002-10-14 ZA ZA200208277A patent/ZA200208277B/en unknown
Also Published As
Publication number | Publication date |
---|---|
YU68902A (sh) | 2004-12-31 |
ZA200208277B (en) | 2004-01-30 |
PL364159A1 (en) | 2004-12-13 |
JP2004500397A (ja) | 2004-01-08 |
WO2001068150A1 (en) | 2001-09-20 |
AU5218901A (en) | 2001-09-24 |
CN1424919A (zh) | 2003-06-18 |
CA2400906A1 (en) | 2001-09-20 |
EE200200524A (et) | 2004-04-15 |
IL151472A0 (en) | 2003-04-10 |
CZ20023101A3 (cs) | 2003-01-15 |
US20030157023A1 (en) | 2003-08-21 |
KR20030041859A (ko) | 2003-05-27 |
BG107085A (bg) | 2004-04-30 |
EA200200881A1 (ru) | 2003-06-26 |
NO20024382D0 (no) | 2002-09-13 |
HUP0300355A2 (hu) | 2003-06-28 |
DE10013850A1 (de) | 2001-09-20 |
NO20024382L (no) | 2002-09-13 |
SK13202002A3 (sk) | 2003-02-04 |
MXPA02008874A (es) | 2003-02-10 |
EP1267947A1 (en) | 2003-01-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |