BR0108607A - Derivados de aminossulfonilbifenila - Google Patents
Derivados de aminossulfonilbifenilaInfo
- Publication number
- BR0108607A BR0108607A BR0108607-3A BR0108607A BR0108607A BR 0108607 A BR0108607 A BR 0108607A BR 0108607 A BR0108607 A BR 0108607A BR 0108607 A BR0108607 A BR 0108607A
- Authority
- BR
- Brazil
- Prior art keywords
- derivatives
- aminosulfonylbiphenyl
- compounds
- aminosulphonybyphenyl
- viia
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
- C07C311/46—Y being a hydrogen or a carbon atom
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
"DERIVADOS DE AMINOSSULFONILBIFENILA". A invenção refere-se a compostos da fórmula I: na qual R^1^,R^2^, R^3^,R^4^, W e X e V têm os significados indicados no texto. Os compostos atuam como inibidores dos fatores Xa e VIIa e podem, por essa razão ser empregados para o controle e a prevenção de distúrbios tromboembólicos, tais como trombose, infarto do miocárdio, arteriosclerose, inflamação, apoplexia, angina pectoris, restenose após a angioplastia e claudicação intermitente.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10008329A DE10008329A1 (de) | 2000-02-23 | 2000-02-23 | Aminosulfonylbiphenylderivate |
PCT/EP2001/002034 WO2001062717A1 (de) | 2000-02-23 | 2001-02-22 | Aminosulfonylbiphenylderivate |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0108607A true BR0108607A (pt) | 2002-11-19 |
Family
ID=7632028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0108607-3A BR0108607A (pt) | 2000-02-23 | 2001-02-22 | Derivados de aminossulfonilbifenila |
Country Status (19)
Country | Link |
---|---|
US (1) | US20030135055A1 (pt) |
EP (1) | EP1257530A1 (pt) |
JP (1) | JP2003524651A (pt) |
KR (1) | KR20020091092A (pt) |
CN (1) | CN1404467A (pt) |
AU (1) | AU2001254661A1 (pt) |
BR (1) | BR0108607A (pt) |
CA (1) | CA2399018A1 (pt) |
CZ (1) | CZ20022783A3 (pt) |
DE (1) | DE10008329A1 (pt) |
HK (1) | HK1052499A1 (pt) |
HU (1) | HUP0300008A2 (pt) |
MX (1) | MXPA02008207A (pt) |
NO (1) | NO20023998D0 (pt) |
PL (1) | PL356565A1 (pt) |
RU (1) | RU2002123337A (pt) |
SK (1) | SK11992002A3 (pt) |
WO (1) | WO2001062717A1 (pt) |
ZA (1) | ZA200205482B (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7030141B2 (en) | 2001-11-29 | 2006-04-18 | Christopher Franklin Bigge | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade |
DE10204072A1 (de) * | 2002-01-31 | 2003-08-14 | Morphochem Ag Komb Chemie | Neue Verbindungen, die Faktor Xa-Aktivität inhibieren |
KR20060115753A (ko) * | 2003-12-22 | 2006-11-09 | 머크 앤드 캄파니 인코포레이티드 | 브라디키닌 길항제 또는 역 효능제로서의 알파-하이드록시아미드 |
MX2007008290A (es) | 2005-01-07 | 2008-02-15 | Synta Pharmaceuticals Corp | Compuestos para inflamacion y usos inmuno-relacionados. |
EP1983971A4 (en) | 2006-01-25 | 2010-11-24 | Synta Pharmaceuticals Corp | SUBSTITUTED AROMATIC COMPOUNDS FOR USE AGAINST INFLAMMATION AND IMMUNE DISORDERS |
TW200806292A (en) | 2006-01-25 | 2008-02-01 | Synta Pharmaceuticals Corp | Vinyl-phenyl derivatives for inflammation and immune-related uses |
US8044242B2 (en) | 2006-03-09 | 2011-10-25 | Bristol-Myers Squibb Company | 2-(aryloxy) acetamide factor VIIa inhibitors useful as anticoagulants |
EP2084127A1 (en) | 2006-11-13 | 2009-08-05 | Pfizer Products Inc. | Diaryl, dipyridinyl and aryl-pyridinyl derivatives and uses thereof |
KR20200123866A (ko) | 2007-02-09 | 2020-10-30 | 메타베이시스 테라퓨틱스, 인크. | 글루카곤 수용체의 길항제 |
EP2326618B1 (en) | 2008-08-13 | 2014-10-15 | Metabasis Therapeutics, Inc. | Glucagon antagonists |
EP3154956A4 (en) | 2014-06-12 | 2018-01-17 | Ligand Pharmaceuticals, Inc. | Glucagon antagonists |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU6645998A (en) * | 1996-12-23 | 1998-07-17 | Du Pont Pharmaceuticals Company | Oxygen or sulfur containing heteroaromatics as factor xa inhibitors |
WO1999041231A1 (fr) * | 1998-02-17 | 1999-08-19 | Ono Pharmaceutical Co., Ltd. | Derives amidino utilises comme ingredients actifs et medicaments les contenant |
JP2003500386A (ja) * | 1999-05-24 | 2003-01-07 | シーオーアール セラピューティクス インコーポレイテッド | Xa因子阻害剤 |
AU5158100A (en) * | 1999-05-24 | 2000-12-12 | Cor Therapeutics, Inc. | Inhibitors of factor xa |
-
2000
- 2000-02-23 DE DE10008329A patent/DE10008329A1/de not_active Withdrawn
-
2001
- 2001-02-22 BR BR0108607-3A patent/BR0108607A/pt not_active Application Discontinuation
- 2001-02-22 AU AU2001254661A patent/AU2001254661A1/en not_active Abandoned
- 2001-02-22 PL PL01356565A patent/PL356565A1/xx unknown
- 2001-02-22 JP JP2001561727A patent/JP2003524651A/ja active Pending
- 2001-02-22 RU RU2002123337/04A patent/RU2002123337A/ru unknown
- 2001-02-22 SK SK1199-2002A patent/SK11992002A3/sk unknown
- 2001-02-22 CN CN01805418A patent/CN1404467A/zh active Pending
- 2001-02-22 WO PCT/EP2001/002034 patent/WO2001062717A1/de not_active Application Discontinuation
- 2001-02-22 US US10/204,455 patent/US20030135055A1/en not_active Abandoned
- 2001-02-22 MX MXPA02008207A patent/MXPA02008207A/es unknown
- 2001-02-22 HU HU0300008A patent/HUP0300008A2/hu unknown
- 2001-02-22 KR KR1020027010594A patent/KR20020091092A/ko not_active Application Discontinuation
- 2001-02-22 CZ CZ20022783A patent/CZ20022783A3/cs unknown
- 2001-02-22 CA CA002399018A patent/CA2399018A1/en not_active Abandoned
- 2001-02-22 EP EP01927690A patent/EP1257530A1/de not_active Withdrawn
-
2002
- 2002-07-09 ZA ZA200205482A patent/ZA200205482B/xx unknown
- 2002-08-22 NO NO20023998A patent/NO20023998D0/no not_active Application Discontinuation
-
2003
- 2003-07-09 HK HK03104902.6A patent/HK1052499A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
WO2001062717A1 (de) | 2001-08-30 |
CN1404467A (zh) | 2003-03-19 |
CZ20022783A3 (cs) | 2002-11-13 |
KR20020091092A (ko) | 2002-12-05 |
NO20023998L (no) | 2002-08-22 |
PL356565A1 (en) | 2004-06-28 |
US20030135055A1 (en) | 2003-07-17 |
HK1052499A1 (zh) | 2003-09-19 |
HUP0300008A2 (hu) | 2003-06-28 |
RU2002123337A (ru) | 2004-01-10 |
MXPA02008207A (es) | 2002-11-29 |
NO20023998D0 (no) | 2002-08-22 |
ZA200205482B (en) | 2003-12-31 |
EP1257530A1 (de) | 2002-11-20 |
DE10008329A1 (de) | 2001-08-30 |
CA2399018A1 (en) | 2001-08-30 |
SK11992002A3 (sk) | 2003-01-09 |
AU2001254661A1 (en) | 2001-09-03 |
JP2003524651A (ja) | 2003-08-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |