BR0108007A - Pyrrole-isoquinoline derivatives and tetrahydropyrrole-isoquinoline and their uses as mediators of the 5-ht7 receptor - Google Patents
Pyrrole-isoquinoline derivatives and tetrahydropyrrole-isoquinoline and their uses as mediators of the 5-ht7 receptorInfo
- Publication number
- BR0108007A BR0108007A BR0108007-5A BR0108007A BR0108007A BR 0108007 A BR0108007 A BR 0108007A BR 0108007 A BR0108007 A BR 0108007A BR 0108007 A BR0108007 A BR 0108007A
- Authority
- BR
- Brazil
- Prior art keywords
- isoquinoline
- mediators
- receptor
- tetrahydropyrrole
- pyrrole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Urology & Nephrology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
"DERIVADOS DA PIRROLO-ISOQUINOLINA E TETRAIDROPIRROLO-ISOQUINOLINA E SEUS USOS COMO MEDIADORES DO RECEPTOR DA 5-HT7". A invenção refere-se aos compostos de fórmula I que são úteis no tratamento da ansiedade, depressão e distúrbios relacionados do sistema nervoso central e outras condições tais como esquizofrenia, distúrbios do sono, incluindo casos de ritmo circadiano, no tratamento da abstinência do álcool e drogas e na disfunção sexual."PIRROLO-ISOQUINOLINE AND TETRAHYDROPIRROLO-ISOQUINOLIN DERIVATIVES AND THEIR USES AS MEDIATORS OF THE 5-HT7 RECEPTOR". The invention relates to compounds of formula I which are useful in the treatment of anxiety, depression and related disorders of the central nervous system and other conditions such as schizophrenia, sleep disorders, including cases of circadian rhythm, in the treatment of alcohol withdrawal and drugs and sexual dysfunction.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49737900A | 2000-02-04 | 2000-02-04 | |
PCT/US2001/003430 WO2001057039A1 (en) | 2000-02-04 | 2001-02-02 | Pyrrolo-isoquinoline and tetrahydropyrrolo-isoquinoline derivatives and their use as mediators of the 5-ht7 receptor |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0108007A true BR0108007A (en) | 2002-10-29 |
Family
ID=23976619
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0108007-5A BR0108007A (en) | 2000-02-04 | 2001-02-02 | Pyrrole-isoquinoline derivatives and tetrahydropyrrole-isoquinoline and their uses as mediators of the 5-ht7 receptor |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1252161A1 (en) |
JP (1) | JP2003522178A (en) |
CN (1) | CN1168728C (en) |
AU (1) | AU2001231287A1 (en) |
BR (1) | BR0108007A (en) |
CA (1) | CA2399545A1 (en) |
MX (1) | MXPA02007521A (en) |
WO (1) | WO2001057039A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103788089A (en) | 2003-09-17 | 2014-05-14 | 詹森药业有限公司 | Fused heterocyclic compounds as serotonin receptor modulators |
US7598255B2 (en) | 2005-08-04 | 2009-10-06 | Janssen Pharmaceutica Nv | Pyrimidine compounds as serotonin receptor modulators |
WO2007053353A2 (en) * | 2005-10-28 | 2007-05-10 | Wyeth | Pyrrolo[2,3-f] and [3,2-f]isoquinolinone derivatives as 5-hydroxytryptamine-6 ligands |
EP2676954A1 (en) * | 2012-06-19 | 2013-12-25 | Laboratorios del Dr. Esteve S.A. | Heterocyclyl-substituted-phenyl derivatives as vasodilators |
-
2001
- 2001-02-02 CA CA002399545A patent/CA2399545A1/en not_active Abandoned
- 2001-02-02 JP JP2001557871A patent/JP2003522178A/en active Pending
- 2001-02-02 CN CNB018044328A patent/CN1168728C/en not_active Expired - Fee Related
- 2001-02-02 EP EP01903486A patent/EP1252161A1/en not_active Withdrawn
- 2001-02-02 BR BR0108007-5A patent/BR0108007A/en not_active IP Right Cessation
- 2001-02-02 MX MXPA02007521A patent/MXPA02007521A/en not_active Application Discontinuation
- 2001-02-02 WO PCT/US2001/003430 patent/WO2001057039A1/en not_active Application Discontinuation
- 2001-02-02 AU AU2001231287A patent/AU2001231287A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1252161A1 (en) | 2002-10-30 |
CN1168728C (en) | 2004-09-29 |
WO2001057039A1 (en) | 2001-08-09 |
AU2001231287A1 (en) | 2001-08-14 |
MXPA02007521A (en) | 2002-12-13 |
CN1396921A (en) | 2003-02-12 |
JP2003522178A (en) | 2003-07-22 |
CA2399545A1 (en) | 2001-08-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: dismissal - article 86 of industrial property law |
Free format text: REFERENTE A 6O, 7O E 8O ANUIDADES. |
|
B08H | Application fees: decision cancelled |
Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2016 DE 25/08/2009 POR TER SIDO INDEVIDO. |
|
B08F | Application fees: dismissal - article 86 of industrial property law |
Free format text: REFERENTE 7A,8A E 9A ANUIDADES. |
|
B08K | Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87) |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2047 DE 30/03/2010. |