BR0017067A - Inibidor de divisão de célula, desidrogenase, método para a produção de um inibidor de divisão de célula e composto - Google Patents

Inibidor de divisão de célula, desidrogenase, método para a produção de um inibidor de divisão de célula e composto

Info

Publication number
BR0017067A
BR0017067A BR0017067-4A BR0017067A BR0017067A BR 0017067 A BR0017067 A BR 0017067A BR 0017067 A BR0017067 A BR 0017067A BR 0017067 A BR0017067 A BR 0017067A
Authority
BR
Brazil
Prior art keywords
inhibitor
cell division
dehydrogenase
producing
compound
Prior art date
Application number
BR0017067-4A
Other languages
English (en)
Inventor
Kanzaki
Hiroshi
Kanoh
Kaneo
Yanagisawa Satohiro
Nitoda
Teruhiko
Akazawa
Kazumi
Original Assignee
Nereus Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nereus Pharmaceuticals Inc filed Critical Nereus Pharmaceuticals Inc
Publication of BR0017067A publication Critical patent/BR0017067A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

"INIBIDOR DE DIVISãO DE CéLULA, DESIDROGENASE, MéTODO PARA A PRODUçãO DE UM INIBIDOR DE DIVISãO DE CéLULA E COMPOSTO". A presente invenção se refere a um inibidor de divisão de célula o qual compreende diversas dehidrodiceto piperazinas tais como dehidrofenilaistina, ou análogos da mesma como o ingrediente ativo, e uma desidrogenase e a um método para a produção do mesmo inibidor.
BR0017067-4A 2000-01-18 2000-09-29 Inibidor de divisão de célula, desidrogenase, método para a produção de um inibidor de divisão de célula e composto BR0017067A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000009370 2000-01-18
PCT/JP2000/006807 WO2001053290A1 (fr) 2000-01-18 2000-09-29 Inhibiteurs de la division cellulaire et procede de production de ces inhibiteurs

Publications (1)

Publication Number Publication Date
BR0017067A true BR0017067A (pt) 2002-10-22

Family

ID=18537534

Family Applications (2)

Application Number Title Priority Date Filing Date
BR0017067-4A BR0017067A (pt) 2000-01-18 2000-09-29 Inibidor de divisão de célula, desidrogenase, método para a produção de um inibidor de divisão de célula e composto
BRPI0017067A BRPI0017067B8 (pt) 2000-01-18 2000-09-29 inibidor de divisão de célula, desidrogenase, método para a produção de um inibidor de divisão de célula e composto

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI0017067A BRPI0017067B8 (pt) 2000-01-18 2000-09-29 inibidor de divisão de célula, desidrogenase, método para a produção de um inibidor de divisão de célula e composto

Country Status (12)

Country Link
US (2) US6972289B1 (pt)
EP (1) EP1264831A4 (pt)
JP (1) JP4810043B2 (pt)
KR (1) KR100831400B1 (pt)
AU (2) AU782917C (pt)
BR (2) BR0017067A (pt)
CA (1) CA2403790C (pt)
IL (2) IL150430A0 (pt)
MX (1) MXPA02006826A (pt)
NZ (1) NZ519989A (pt)
WO (1) WO2001053290A1 (pt)
ZA (1) ZA200206576B (pt)

Families Citing this family (32)

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Publication number Priority date Publication date Assignee Title
ES2561212T3 (es) 1997-06-09 2016-02-25 Hitachi, Ltd. Procedimiento de decodificación de imágenes
US7026322B2 (en) * 1998-11-12 2006-04-11 Nereus Pharmaceuticals, Inc. Phenylahistin and the phenylahistin analogs, a new class of anti-tumor compounds
MXPA02006826A (es) * 2000-01-18 2004-04-05 Nereus Phamraceuticals Inc Un inhibidor de division celular y un metodo de produccion del mismo.
US7919497B2 (en) 2002-08-02 2011-04-05 Nereus Pharmaceuticals, Inc. Analogs of dehydrophenylahistins and their therapeutic use
CN101633655B (zh) * 2002-08-02 2014-04-30 大连万***业有限公司 脱氢苯基阿夕斯丁及其类似物以及脱氢苯基阿夕斯丁及其类似物的合成
BRPI0313363A8 (pt) * 2002-08-02 2019-01-02 Beyondspring Pharmaceuticals Inc dehidrofenilahistinas e seus análogos, e sua síntese
US7935704B2 (en) 2003-08-01 2011-05-03 Nereus Pharmaceuticals, Inc. Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof
AU2003303045A1 (en) * 2002-12-18 2004-07-09 Pfizer Products Inc. 4-anilino quinazoline derivatives for the treatment of abnormal cell growth
GR1004602B (el) * 2003-07-03 2004-06-18 Μεθοδοι παρασκευης παραγωγων δεϋδρο-δικετοπιπεραζινων
CN1934101B (zh) * 2004-02-04 2011-10-12 尼瑞斯药品公司 脱氢苯基阿夕斯丁及其类似物以及脱氢苯基阿夕斯丁及其类似物的合成
KR101228104B1 (ko) * 2004-02-04 2013-02-01 니리어스 파마슈티컬즈, 인코퍼레이션 데하이드로페닐아히스틴 및 그의 동족체, 및 이들의합성방법
US7732605B2 (en) * 2005-03-29 2010-06-08 Nereus Pharmaceuticals, Inc. Synthesis of diketopiperazines
AR058408A1 (es) * 2006-01-02 2008-01-30 Basf Ag Compuestos de piperazina con accion herbicida
TWI403269B (zh) * 2006-01-05 2013-08-01 Basf Ag 具有除草作用之哌化合物
US8129527B2 (en) 2006-11-03 2012-03-06 Nereus Pharmacuticals, Inc. Analogs of dehydrophenylahistins and their therapeutic use
PE20090417A1 (es) * 2007-06-12 2009-05-08 Basf Se Compuestos de piperazina con accion herbicida
WO2008152072A2 (de) * 2007-06-12 2008-12-18 Basf Se Piperazinverbindungen mit herbizider wirkung
JP2010529170A (ja) * 2007-06-12 2010-08-26 ビーエーエスエフ ソシエタス・ヨーロピア 除草活性組成物
BRPI0916684A2 (pt) * 2008-07-29 2015-08-04 Basf Se Compostos de piperazina, composição, e, processo para combater vegetação indesejada
EP2318379A1 (de) * 2008-08-13 2011-05-11 Basf Se Verfahren zur herstellung von piperazindion-derivaten
JP2012504576A (ja) * 2008-10-02 2012-02-23 ビーエーエスエフ ソシエタス・ヨーロピア 除草活性を有するピペラジン化合物
RU2736045C2 (ru) 2015-03-06 2020-11-11 Бейондспринг Фармасьютикалс, Инк. Способ лечения рака, ассоциированного с мутацией ras
CN107530340B (zh) 2015-03-06 2021-06-08 大连万春布林医药有限公司 治疗脑肿瘤的方法
US10155748B2 (en) 2015-07-13 2018-12-18 Beyondspring Pharmaceuticals, Inc. Plinabulin compositions
NZ744854A (en) 2016-02-08 2020-01-31 Beyondspring Pharmaceuticals Inc Compositions containing tucaresol or its analogs
KR20190015361A (ko) 2016-06-06 2019-02-13 비욘드스프링 파마수티컬스, 인코포레이티드. 호중구감소증을 줄이는 조성물 및 방법
CN109563079B (zh) 2016-08-12 2021-10-26 深圳华大海洋科技有限公司 脱氢苯基阿夕斯丁类化合物的多晶型及其制备纯化方法和应用
CN106565686B (zh) * 2016-10-11 2019-03-01 深圳海王医药科技研究院有限公司 微管蛋白抑制剂
WO2018129381A1 (en) 2017-01-06 2018-07-12 Beyondspring Pharmaceuticals, Inc. Tubulin binding compounds and therapeutic use thereof
KR20190109479A (ko) 2017-02-01 2019-09-25 비욘드스프링 파마수티컬스, 인코포레이티드. 호중구감소증의 감소 방법
BR112020014960A2 (pt) 2018-01-24 2020-12-22 Beyondspring Pharmaceuticals, Inc. Composição e método para redução de trombocitopenia
KR20220117501A (ko) 2021-02-17 2022-08-24 주식회사 티제이 카드리더기 모듈의 슬림화장치

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0725858A (ja) * 1993-07-13 1995-01-27 Otsuka Pharmaceut Co Ltd ピペラジン誘導体
GB9402807D0 (en) * 1994-02-14 1994-04-06 Xenova Ltd Pharmaceutical compounds
GB9402809D0 (en) * 1994-02-14 1994-04-06 Xenova Ltd Pharmaceutical compounds
GB9426224D0 (en) * 1994-12-23 1995-02-22 Xenova Ltd Pharmaceutical compounds
JP3131574B2 (ja) * 1996-09-04 2001-02-05 新日本製鐵株式会社 新規抗腫瘍物質、該物質を製造するための微生物及び方法、並びに該物質を有効成分とする細胞周期阻害剤及び抗腫瘍剤
US6069146A (en) * 1998-03-25 2000-05-30 The Regents Of The University Of California Halimide, a cytotoxic marine natural product, and derivatives thereof
US6358957B1 (en) * 1998-11-12 2002-03-19 Nereus Pharmaceuticals, Inc. Phenylahistin and the phenylahistin analogs, a new class of anti-tumor compounds
MXPA02006826A (es) * 2000-01-18 2004-04-05 Nereus Phamraceuticals Inc Un inhibidor de division celular y un metodo de produccion del mismo.
BRPI0313363A8 (pt) * 2002-08-02 2019-01-02 Beyondspring Pharmaceuticals Inc dehidrofenilahistinas e seus análogos, e sua síntese
US7919497B2 (en) * 2002-08-02 2011-04-05 Nereus Pharmaceuticals, Inc. Analogs of dehydrophenylahistins and their therapeutic use

Also Published As

Publication number Publication date
US6972289B1 (en) 2005-12-06
EP1264831A4 (en) 2005-11-23
AU782917C (en) 2006-11-23
AU2005242133B2 (en) 2009-09-03
ZA200206576B (en) 2003-05-12
BRPI0017067B8 (pt) 2021-05-25
JP4810043B2 (ja) 2011-11-09
NZ519989A (en) 2004-05-28
IL150430A (en) 2011-03-31
CA2403790C (en) 2011-09-27
WO2001053290A1 (fr) 2001-07-26
AU7451100A (en) 2001-07-31
IL150430A0 (en) 2002-12-01
MXPA02006826A (es) 2004-04-05
AU2005242133A1 (en) 2006-01-05
KR20020082484A (ko) 2002-10-31
AU782917B2 (en) 2005-09-08
EP1264831A1 (en) 2002-12-11
KR100831400B1 (ko) 2008-05-21
US20060079534A1 (en) 2006-04-13
CA2403790A1 (en) 2001-07-26
BRPI0017067B1 (pt) 2019-08-27

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B25A Requested transfer of rights approved

Owner name: DALIAN WANCHUN BIOTECHNOLOGY CO., LTD. (CN)

B25A Requested transfer of rights approved

Owner name: BEYONDSPRING PHARMACEUTICALS, INC (US)

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