BR0015392A - Lipoxina a4 e seus análogos para o tratamento de olho ressecado - Google Patents

Lipoxina a4 e seus análogos para o tratamento de olho ressecado

Info

Publication number
BR0015392A
BR0015392A BR0015392-3A BR0015392A BR0015392A BR 0015392 A BR0015392 A BR 0015392A BR 0015392 A BR0015392 A BR 0015392A BR 0015392 A BR0015392 A BR 0015392A
Authority
BR
Brazil
Prior art keywords
analogs
lipoxin
treatment
dry eye
disclosed
Prior art date
Application number
BR0015392-3A
Other languages
English (en)
Inventor
Daniel A Gamache
Gustav Graff
Mark R Hellberg
Peter G Klimko
John M Yanni
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of BR0015392A publication Critical patent/BR0015392A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Abstract

"LIPOXINA A~ 4~ E SEUS ANáLOGOS PARA O TRATAMENTO DE OLHO RESSECADO". Estão descritos composições oftálmicas contendo lipoxina A~ 4~ e seus análogos e métodos de uso dos mesmos para tratamento de olho ressecado.
BR0015392-3A 1999-11-09 2000-11-08 Lipoxina a4 e seus análogos para o tratamento de olho ressecado BR0015392A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16440699P 1999-11-09 1999-11-09
PCT/US2000/030707 WO2001034144A1 (en) 1999-11-09 2000-11-08 Lipoxin a4 and its analogs for the treatment of dry eye

Publications (1)

Publication Number Publication Date
BR0015392A true BR0015392A (pt) 2002-06-25

Family

ID=22594348

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0015392-3A BR0015392A (pt) 1999-11-09 2000-11-08 Lipoxina a4 e seus análogos para o tratamento de olho ressecado

Country Status (17)

Country Link
US (1) US6645978B1 (pt)
EP (1) EP1237549B1 (pt)
JP (1) JP2003514782A (pt)
CN (1) CN1387435A (pt)
AT (1) ATE258791T1 (pt)
AU (1) AU1475701A (pt)
BR (1) BR0015392A (pt)
CA (1) CA2386878A1 (pt)
DE (1) DE60008143T2 (pt)
DK (1) DK1237549T3 (pt)
ES (1) ES2215752T3 (pt)
HK (1) HK1046365A1 (pt)
MX (1) MXPA02004617A (pt)
PL (1) PL356100A1 (pt)
PT (1) PT1237549E (pt)
TR (2) TR200400526T4 (pt)
WO (1) WO2001034144A1 (pt)

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Publication number Priority date Publication date Assignee Title
US8722654B2 (en) * 2001-03-02 2014-05-13 The Brigham And Women's Hospital, Inc. Lipoxin analogs as novel inhibitors of angiogenesis
JP2005505592A (ja) * 2001-10-11 2005-02-24 アルコン，インコーポレイテッド 抗炎症性ステロイドとｍｕｃ−１分泌促進薬との組み合わせによる、ドライアイを処置するための方法
US6831186B2 (en) 2001-11-06 2004-12-14 Schering Aktiengesellschft Lipoxin A4 analogs
US7795203B2 (en) * 2002-09-30 2010-09-14 Babizhayev Mark A Method for topical treatment of eye disease and composition and device for said treatment
US9216106B2 (en) * 2003-04-09 2015-12-22 Directcontact Llc Device and method for the delivery of drugs for the treatment of posterior segment disease
US20050208102A1 (en) * 2003-04-09 2005-09-22 Schultz Clyde L Hydrogels used to deliver medicaments to the eye for the treatment of posterior segment diseases
US20050074497A1 (en) * 2003-04-09 2005-04-07 Schultz Clyde L. Hydrogels used to deliver medicaments to the eye for the treatment of posterior segment diseases
US20050255144A1 (en) * 2003-04-09 2005-11-17 Directcontact Llc Methods and articles for the delivery of medicaments to the eye for the treatment of posterior segment diseases
US7923471B2 (en) * 2004-05-14 2011-04-12 Alcon, Inc. Method of treating dry eye disorders and uveitis
MXPA06013170A (es) * 2004-05-14 2007-02-13 Alcon Inc Metodo para tratar trastornos de queratoconjuntivitis seca y uveitis.
ATE452659T1 (de) * 2004-10-01 2010-01-15 Menicon Co Ltd Verfahren zur sterilisation verpackter kontaktlinsen mit verpackungslösung
US7879905B2 (en) * 2004-11-09 2011-02-01 Alcon, Inc. 5,6,7-trihydroxyheptanoic acid and analogs for the treatment of ocular diseases and diseases associated with hyperproliferative and angiogenic responses
WO2006068795A2 (en) * 2004-12-16 2006-06-29 Alcon, Inc. Use of inhibitors of formyl peptide receptors for reducing intraocular pressure
US20060154981A1 (en) * 2005-01-12 2006-07-13 Alcon, Inc. Method of reducing intraocular pressure and treating glaucoma
US7687539B1 (en) * 2005-11-07 2010-03-30 Alcon Research, Ltd. Method of treating ocular allergy
CL2007003468A1 (es) 2006-12-04 2008-07-04 Bayer Schering Pharma Ag Sal de potasio cristalina de analogos de lipoxina a4; metodode sintesis; composicion farmaceutica; y uso en el tratamiento de trastornos inflamatorios o autoinmunes.
AU2014201375B2 (en) * 2007-10-12 2015-11-05 Resolvyx Pharmaceuticals, Inc. Omega-3 fatty acids, hydroxy polyunsaturated fatty acids, lipoxin compounds, or oxylipin compounds for the treatment of ophthalmic conditions
CA2702475A1 (en) * 2007-10-12 2009-04-23 Resolvyx Pharmaceuticals, Inc. Compositions and methods for the treatment of ophthalmic conditions
EP2219638A2 (en) * 2007-10-29 2010-08-25 Board of Supervisors of Louisiana State University and Agricultural and Mechanical College Lipoxin a4 protection for retinal cells
US8729128B2 (en) * 2007-10-30 2014-05-20 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Lipoxin A4 protection for cornea endothelial cells
US8865685B2 (en) * 2011-06-30 2014-10-21 Johnson & Johnson Vision Care, Inc. Esters for treatment of ocular inflammatory conditions
WO2018067694A1 (en) * 2016-10-04 2018-04-12 UND Life Sciences, LLC Composition of bioactive lipids and methods of use thereof
WO2018161175A1 (en) * 2017-03-09 2018-09-13 University Health Network Lipoxin and lipoxin analogue mediated neuroprotection and treatments

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US4131651A (en) 1977-10-25 1978-12-26 Barnes-Hind Pharmaceuticals, Inc. Treatment of dry eye
US4409205A (en) 1979-03-05 1983-10-11 Cooper Laboratories, Inc. Ophthalmic solution
US4370325A (en) 1979-03-30 1983-01-25 Dermik Laboratories Pharmaceutical compositions and method of treatment
US4576758A (en) * 1984-06-01 1986-03-18 The Upjohn Company Anti-inflammatory lipoxin B analogs
US4753945A (en) 1986-02-19 1988-06-28 Eye Research Institute Of Retina Foundation Stimulation of tear secretion with phosphodiesterase inhibitors
US4868154A (en) 1986-02-19 1989-09-19 Eye Research Institute Of Retina Foundation Stimulation of tear secretion with melanocyte stimulating hormones
US4883658A (en) 1986-04-28 1989-11-28 Holly Frank J Ophthalmic solution for treatment of dry-eye syndrome
US4744980A (en) 1986-04-28 1988-05-17 Holly Frank J Ophthalmic solution for treatment of dry eye syndrome
US4804539A (en) 1986-07-28 1989-02-14 Liposome Technology, Inc. Ophthalmic liposomes
US4818537A (en) 1986-10-21 1989-04-04 Liposome Technology, Inc. Liposome composition for treating dry eye
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US5278151A (en) 1987-04-02 1994-01-11 Ocular Research Of Boston, Inc. Dry eye treatment solution
US5075104A (en) 1989-03-31 1991-12-24 Alcon Laboratories, Inc. Ophthalmic carboxy vinyl polymer gel for dry eye syndrome
US5079261A (en) * 1989-04-28 1992-01-07 Brigham And Women's Hospital Use of lipoxin a4 and its derivatives as antagonists for slow-reacting substances of anaphylaxis
US5174988A (en) 1989-07-27 1992-12-29 Scientific Development & Research, Inc. Phospholipid delivery system
US5041434A (en) 1991-08-17 1991-08-20 Virginia Lubkin Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application
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DE69212850T2 (de) 1991-01-15 1997-03-06 Alcon Lab Inc Verwendung von Karrageenan in topischen ophthalmologischen Zusammensetzungen
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Also Published As

Publication number Publication date
PL356100A1 (en) 2004-06-14
WO2001034144A1 (en) 2001-05-17
PT1237549E (pt) 2004-06-30
TR200201244T2 (tr) 2002-08-21
ES2215752T3 (es) 2004-10-16
MXPA02004617A (es) 2004-09-10
DK1237549T3 (da) 2004-06-07
DE60008143T2 (de) 2004-12-30
ATE258791T1 (de) 2004-02-15
DE60008143D1 (de) 2004-03-11
EP1237549B1 (en) 2004-02-04
JP2003514782A (ja) 2003-04-22
US6645978B1 (en) 2003-11-11
AU1475701A (en) 2001-06-06
CA2386878A1 (en) 2001-05-17
HK1046365A1 (zh) 2003-01-10
CN1387435A (zh) 2002-12-25
EP1237549A1 (en) 2002-09-11
TR200400526T4 (tr) 2004-04-21

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]