BR0013283A - Agente farmacêutico que compreende um derivado de benzamida como ingrediente ativo - Google Patents

Agente farmacêutico que compreende um derivado de benzamida como ingrediente ativo

Info

Publication number
BR0013283A
BR0013283A BR0013283-7A BR0013283A BR0013283A BR 0013283 A BR0013283 A BR 0013283A BR 0013283 A BR0013283 A BR 0013283A BR 0013283 A BR0013283 A BR 0013283A
Authority
BR
Brazil
Prior art keywords
benzamide derivative
active ingredient
pharmaceutical agent
formulations
degradation products
Prior art date
Application number
BR0013283-7A
Other languages
English (en)
Inventor
Tsuneji Suzuki
Tomoyuki Ando
Masahiko Ishibashi
Masahiro Sakabe
Ikuo Sakai
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of BR0013283A publication Critical patent/BR0013283A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Patente de Invenção: "AGENTE FARMACêUTICO QUE COMPREENDE UM DERIVADO DE BENZAMIDA COMO INGREDIENTE ATIVO". Esta invenção refere-se a formulações farmacêuticas estáveis que podem ser obtidas misturando um derivado de benzamida farmaceuticamente útil ou um sal do mesmo farmaceuticamente aceitável com aditivos que não produzem facilmente produtos de degradação, combinando um sal de ácido orgânico, um composto de amina e uma substância básica inorgânica, produzindo formulações sólidas pelo método de granulação seca e adicionalmente ajustando o pH das formulações líquidas em 4 a 12. Formulações farmacêuticas que produzem poucos produtos de degradação e que são suficientemente estáveis para ser usadas como drogas médicas podem ser obtidas
BR0013283-7A 1999-08-16 2000-08-16 Agente farmacêutico que compreende um derivado de benzamida como ingrediente ativo BR0013283A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP22955199A JP2001064177A (ja) 1999-08-16 1999-08-16 ベンズアミド誘導体を有効成分とする製剤
PCT/EP2000/008011 WO2001012193A1 (en) 1999-08-16 2000-08-16 Pharmaceutical agent comprising a benzamide derivative as active ingredient

Publications (1)

Publication Number Publication Date
BR0013283A true BR0013283A (pt) 2002-04-23

Family

ID=16893948

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0013283-7A BR0013283A (pt) 1999-08-16 2000-08-16 Agente farmacêutico que compreende um derivado de benzamida como ingrediente ativo

Country Status (29)

Country Link
EP (1) EP1207881B1 (pt)
JP (2) JP2001064177A (pt)
KR (1) KR100683876B1 (pt)
CN (1) CN1205931C (pt)
AR (1) AR031074A1 (pt)
AU (1) AU780151B2 (pt)
BG (1) BG65662B1 (pt)
BR (1) BR0013283A (pt)
CA (1) CA2380757C (pt)
CY (1) CY1116273T1 (pt)
CZ (1) CZ302924B6 (pt)
DK (1) DK1207881T3 (pt)
EE (1) EE05331B1 (pt)
ES (1) ES2536705T3 (pt)
HK (1) HK1046501B (pt)
HR (1) HRP20020181B1 (pt)
HU (1) HU230386B1 (pt)
IL (1) IL148169A0 (pt)
MX (1) MXPA02001575A (pt)
NO (1) NO328957B1 (pt)
NZ (1) NZ517356A (pt)
PL (1) PL201388B1 (pt)
PT (1) PT1207881E (pt)
RU (1) RU2257206C2 (pt)
SK (1) SK287547B6 (pt)
TW (1) TWI245630B (pt)
UA (1) UA73316C2 (pt)
WO (1) WO2001012193A1 (pt)
ZA (1) ZA200201466B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001081031A (ja) * 1999-08-30 2001-03-27 Schering Ag 溶解性および経口吸収性を改善したベンズアミド誘導体含有製剤
AU2001288102A1 (en) * 2000-09-22 2002-04-02 Takeda Chemical Industries Ltd. Solid preparations
AU2003220119A1 (en) 2002-03-07 2003-09-22 University Of Delaware Methods, compositions, and kits for enhancing oligonucleotide-mediated nucleic acid sequence alteration using compositions comprising a histone deacetylase inhibitor, lambda phage beta protein, or hydroxyurea
GB0316206D0 (en) 2003-07-10 2003-08-13 Glaxo Group Ltd Pharmaceutical formulation
EP2135620A4 (en) 2007-03-28 2010-12-29 Santen Pharmaceutical Co Ltd AGAINST OKULAR HYPOTONIA CONNECTED TO HISTONE DEACETYLASE INHIBITION AS AN ACTIVE SUBSTANCE
KR101405615B1 (ko) * 2007-08-27 2014-06-12 (주)아모레퍼시픽 조성물 내 ｐＨ 조절을 통해 안정화된 벤즈아미드 화합물을함유하는 피부 외용제 조성물, 및 그 벤즈아미드 화합물안정화 방법
GB2462893B (en) * 2008-08-29 2010-10-13 Bayer Schering Pharma Ag N-(2-aminophenyl)-4-[N-(pyridine-3-yl)-methoxycarbonyl-aminomethyl]-benzamide (MS-275) polymorph B
NZ591387A (en) * 2008-08-29 2012-03-30 Bayer Pharma AG N-(2-aminophenyl)-4-[n-(pyridine-3-yl)-methoxycarbonyl-aminomethyl]-benzamide (ms-275) polymorph b
WO2014163132A1 (ja) * 2013-04-04 2014-10-09 第一三共株式会社 アミノカルボン酸の塩の固形組成物
EP3272345B1 (en) 2015-03-19 2019-10-16 Daiichi Sankyo Company, Limited Solid preparation containing antioxidant agent
EP3437639A1 (en) 2015-03-19 2019-02-06 Daiichi Sankyo Company, Limited Solid preparation containing colorant
WO2020153520A1 (ko) * 2019-01-25 2020-07-30 (주)아모레퍼시픽 벤조산아마이드 화합물 및 용해보조제를 포함하는 조성물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3354090B2 (ja) * 1996-09-30 2002-12-09 シエーリング アクチエンゲゼルシャフト 分化誘導剤
US6174905B1 (en) * 1996-09-30 2001-01-16 Mitsui Chemicals, Inc. Cell differentiation inducer

Also Published As

Publication number Publication date
HK1046501B (zh) 2005-09-30
PL201388B1 (pl) 2009-04-30
AR031074A1 (es) 2003-09-10
CN1370068A (zh) 2002-09-18
ES2536705T3 (es) 2015-05-27
CN1205931C (zh) 2005-06-15
EP1207881B1 (en) 2015-04-01
UA73316C2 (uk) 2005-07-15
HU230386B1 (hu) 2016-03-29
RU2257206C2 (ru) 2005-07-27
CZ2002540A3 (cs) 2002-06-12
HUP0203226A2 (hu) 2003-01-28
TWI245630B (en) 2005-12-21
HK1046501A1 (en) 2003-01-17
KR100683876B1 (ko) 2007-02-15
JP4854158B2 (ja) 2012-01-18
EP1207881A1 (en) 2002-05-29
PL353449A1 (en) 2003-11-17
CZ302924B6 (cs) 2012-01-18
IL148169A0 (en) 2002-09-12
SK287547B6 (sk) 2011-01-04
HRP20020181B1 (hr) 2016-01-29
ZA200201466B (en) 2002-09-02
CA2380757A1 (en) 2001-02-22
CY1116273T1 (el) 2017-02-08
JP2001064177A (ja) 2001-03-13
HRP20020181A2 (en) 2005-10-31
WO2001012193A1 (en) 2001-02-22
NO20020774D0 (no) 2002-02-15
HUP0203226A3 (en) 2003-12-29
AU780151B2 (en) 2005-03-03
NO20020774L (no) 2002-03-04
BG106516A (en) 2002-10-31
AU6442700A (en) 2001-03-13
NZ517356A (en) 2003-07-25
CA2380757C (en) 2009-01-27
EE05331B1 (et) 2010-08-16
BG65662B1 (bg) 2009-05-29
MXPA02001575A (es) 2003-10-14
SK2092002A3 (en) 2002-07-02
NO328957B1 (no) 2010-06-28
EE200200073A (et) 2003-04-15
JP2003507330A (ja) 2003-02-25
DK1207881T3 (da) 2015-06-22
RU2002106815A (ru) 2004-01-27
PT1207881E (pt) 2015-06-05
KR20020020815A (ko) 2002-03-15

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 13, 24 E 25 DA LPI.

B12B Appeal against refusal [chapter 12.2 patent gazette]
B25D Requested change of name of applicant approved

Owner name: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE)

Free format text: NOME ALTERADO DE: SCHERING AKTIENGESELLSCHAFT