BR0012822A - Formulação farmacêutica, e, forma de dosagem em tablete - Google Patents
Formulação farmacêutica, e, forma de dosagem em tableteInfo
- Publication number
- BR0012822A BR0012822A BR0012822-8A BR0012822A BR0012822A BR 0012822 A BR0012822 A BR 0012822A BR 0012822 A BR0012822 A BR 0012822A BR 0012822 A BR0012822 A BR 0012822A
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical formulation
- apomorphine
- dextran
- dosage form
- formulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Abstract
"FORMULAçãO FARMACêUTICA, E, FORMA DE DOSAGEM EM TABLETE". Formulação farmacêutica para a administração na mucosa oral de liberação prolongada de apomorfina que compreende quantidade terapeuticamente efetiva de apomorfina ou sal farmaceuticamente aceitável ou sua pró-droga em combinação com veículo que compreende de cerca de 10 porcento em peso até cerca de 95 porcento em peso de dextrano, baseado no peso total da formulação. Em uma realização da invenção, dextrano que tem peso molecular na faixa entre cerca de 5000 Daltons e 100.000 Daltons no componente único da formulação para prolongar a liberação do componente de droga ativo. Em realização alternativa, mistura de celulose microcristalina e dextrano atua como os componentes para prolongar a liberação de apomorfina.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47584499A | 1999-12-30 | 1999-12-30 | |
PCT/US2000/034548 WO2001049292A1 (en) | 1999-12-30 | 2000-12-19 | Oral mucosal dosage forms of apomorphine |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0012822A true BR0012822A (pt) | 2004-03-09 |
Family
ID=23889387
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0012822-8A BR0012822A (pt) | 1999-12-30 | 2000-12-19 | Formulação farmacêutica, e, forma de dosagem em tablete |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP1242088A1 (pt) |
JP (1) | JP2004501065A (pt) |
CN (1) | CN1414853A (pt) |
AU (1) | AU2440901A (pt) |
BR (1) | BR0012822A (pt) |
CA (1) | CA2394297A1 (pt) |
CZ (1) | CZ20022245A3 (pt) |
HK (1) | HK1051315A1 (pt) |
HU (1) | HUP0400495A3 (pt) |
IL (1) | IL150034A0 (pt) |
MX (1) | MXPA02006034A (pt) |
NO (1) | NO20023190L (pt) |
PL (1) | PL366204A1 (pt) |
WO (1) | WO2001049292A1 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE0202365D0 (sv) | 2002-08-05 | 2002-08-05 | Pharmacia Ab | New formulation and use thereof |
SE0302947D0 (sv) | 2003-01-24 | 2003-11-07 | Magle Ab | A composition material for transmucosal delivery |
EA012306B1 (ru) * | 2003-01-24 | 2009-08-28 | Магле Холдинг Аб | Композиционный материал для доставки через слизистые оболочки |
JP4739189B2 (ja) * | 2004-04-14 | 2011-08-03 | 武田薬品工業株式会社 | 固形製剤 |
GB0509317D0 (en) * | 2005-05-06 | 2005-06-15 | Clarke Anthony | Pharmaceutical formulation of apomorphine |
EA025054B1 (ru) * | 2009-06-12 | 2016-11-30 | Сайнэпсус Терапьютикс, Инк. | Единичная дозированная форма для сублингвального введения, включающая частицы апоморфина, для лечения болезни паркинсона или половой дисфункции |
US20220249465A1 (en) * | 2019-05-31 | 2022-08-11 | Primo Pharmatech Llc | Unit dosage form for transmucosal drug delivery of an active pharmaceutical ingredient |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE290864T1 (de) * | 1993-03-26 | 2005-04-15 | Franciscus Wilhelmus He Merkus | Pharmazeutische zusammensetzungen zur intranasalen verabreichung von dihydroergotamin |
GB9517062D0 (en) * | 1995-08-18 | 1995-10-25 | Scherer Ltd R P | Pharmaceutical compositions |
-
2000
- 2000-12-19 CZ CZ20022245A patent/CZ20022245A3/cs unknown
- 2000-12-19 MX MXPA02006034A patent/MXPA02006034A/es unknown
- 2000-12-19 CN CN00818098A patent/CN1414853A/zh active Pending
- 2000-12-19 JP JP2001549660A patent/JP2004501065A/ja not_active Withdrawn
- 2000-12-19 BR BR0012822-8A patent/BR0012822A/pt not_active IP Right Cessation
- 2000-12-19 EP EP00988174A patent/EP1242088A1/en not_active Withdrawn
- 2000-12-19 AU AU24409/01A patent/AU2440901A/en not_active Abandoned
- 2000-12-19 HU HU0400495A patent/HUP0400495A3/hu unknown
- 2000-12-19 CA CA002394297A patent/CA2394297A1/en not_active Abandoned
- 2000-12-19 PL PL00366204A patent/PL366204A1/xx not_active Application Discontinuation
- 2000-12-19 WO PCT/US2000/034548 patent/WO2001049292A1/en not_active Application Discontinuation
- 2000-12-19 IL IL15003400A patent/IL150034A0/xx unknown
-
2002
- 2002-07-01 NO NO20023190A patent/NO20023190L/no not_active Application Discontinuation
-
2003
- 2003-03-14 HK HK03101912.0A patent/HK1051315A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
HK1051315A1 (zh) | 2003-08-01 |
MXPA02006034A (es) | 2004-08-23 |
WO2001049292A1 (en) | 2001-07-12 |
AU2440901A (en) | 2001-07-16 |
HUP0400495A3 (en) | 2007-05-02 |
NO20023190D0 (no) | 2002-07-01 |
NO20023190L (no) | 2002-08-29 |
IL150034A0 (en) | 2002-12-01 |
EP1242088A1 (en) | 2002-09-25 |
PL366204A1 (en) | 2005-01-24 |
CZ20022245A3 (cs) | 2002-10-16 |
JP2004501065A (ja) | 2004-01-15 |
HUP0400495A2 (hu) | 2004-06-28 |
CN1414853A (zh) | 2003-04-30 |
CA2394297A1 (en) | 2001-07-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A, 8A E 9A ANUIDADES |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2008 DE 30/06/2009. |