BR0009840A - Terapia de combinação para hcv, contendo ribavirina em associação com antioxidantes - Google Patents
Terapia de combinação para hcv, contendo ribavirina em associação com antioxidantesInfo
- Publication number
- BR0009840A BR0009840A BR0009840-0A BR0009840A BR0009840A BR 0009840 A BR0009840 A BR 0009840A BR 0009840 A BR0009840 A BR 0009840A BR 0009840 A BR0009840 A BR 0009840A
- Authority
- BR
- Brazil
- Prior art keywords
- combination
- hcv
- ribavirin
- antioxidants
- combination therapy
- Prior art date
Links
- IWUCXVSUMQZMFG-AFCXAGJDSA-N Ribavirin Chemical compound N1=C(C(=O)N)N=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 IWUCXVSUMQZMFG-AFCXAGJDSA-N 0.000 title abstract 4
- 229960000329 ribavirin Drugs 0.000 title abstract 4
- HZCAHMRRMINHDJ-DBRKOABJSA-N ribavirin Natural products O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1N=CN=C1 HZCAHMRRMINHDJ-DBRKOABJSA-N 0.000 title abstract 4
- 239000003963 antioxidant agent Substances 0.000 title abstract 3
- 238000002648 combination therapy Methods 0.000 title abstract 3
- 206010018910 Haemolysis Diseases 0.000 abstract 1
- 102000006992 Interferon-alpha Human genes 0.000 abstract 1
- 108010047761 Interferon-alpha Proteins 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 208000020403 chronic hepatitis C virus infection Diseases 0.000 abstract 1
- 230000008588 hemolysis Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Patente de Invenção: "TERAPIA DE COMBINAçãO PARA HCV, CONTENDO RIBAVIRINA EM ASSOCIAçãO COM ANTIOXIDANTES". São descritos processos para o tratamento de pacientes que possuem infecções virais, especialmente infecção crónica de hepatite C pela administração ao dito paciente de uma quantidade terapeuticamente eficiente de uma terapia de combinação de interferon-alfa e ribavirina durante um tempo suficiente para diminuir o RNA de HCV em associação com uma quantidade terapeuticamente eficiente de um antioxidante durante um tempo suficiente para melhorar a hemólise relacionada com a ribavirina.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29468799A | 1999-04-19 | 1999-04-19 | |
PCT/US2000/010240 WO2000062799A1 (en) | 1999-04-19 | 2000-04-18 | Hcv combination therapy, containing ribavirin in association with antioxidants |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0009840A true BR0009840A (pt) | 2002-01-08 |
Family
ID=23134504
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0009840-0A BR0009840A (pt) | 1999-04-19 | 2000-04-18 | Terapia de combinação para hcv, contendo ribavirina em associação com antioxidantes |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP1046399A1 (pt) |
JP (1) | JP2002542202A (pt) |
CN (1) | CN1355708A (pt) |
AR (1) | AR023541A1 (pt) |
AU (1) | AU4463300A (pt) |
BR (1) | BR0009840A (pt) |
CA (1) | CA2306039A1 (pt) |
CO (1) | CO5241354A1 (pt) |
HU (1) | HUP0200942A3 (pt) |
MX (1) | MXPA00003974A (pt) |
NO (1) | NO20015059L (pt) |
PE (1) | PE20010284A1 (pt) |
WO (1) | WO2000062799A1 (pt) |
ZA (1) | ZA200108571B (pt) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6274597B1 (en) | 1998-06-01 | 2001-08-14 | Mount Sinai School Of Medicine Of New York University | Method of enhancing lysosomal α-Galactosidase A |
JP2003523978A (ja) | 2000-02-18 | 2003-08-12 | シャイアー・バイオケム・インコーポレイテッド | ヌクレオシドアナログを用いるflavivirus感染の処置もしくは予防するための方法 |
US20020197235A1 (en) * | 2000-11-03 | 2002-12-26 | Moran Stanford Mark | Method for short-term and long-term drug dosimetry |
ITMI20011863A1 (it) * | 2001-09-05 | 2003-03-05 | Zambon Spa | Associazione di farmaci contro il virus dell'influenza |
WO2003024461A1 (en) * | 2001-09-20 | 2003-03-27 | Schering Corporation | Hcv combination therapy |
US20040022873A1 (en) * | 2001-11-09 | 2004-02-05 | Guilford F. Timothy | Systemic administration of NAC as an adjunct in the treatment of bioterror exposures such as anthrax, smallpox or radiation and for vaccination prophylaxis, and use in combination with DHEA for the treatment of smallpox and other viruses |
TWI274585B (en) * | 2002-06-03 | 2007-03-01 | Nat Health Research Institutes | Pharmaceutical composition, kit, and packaged product for treating infection by a flaviviridae virus |
EP1567172A2 (en) * | 2002-11-29 | 2005-08-31 | GPC Biotech AG | Formulations useful against hepatitis c virus infections |
US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
CA2516333C (en) * | 2003-02-21 | 2011-08-23 | Mochida Pharmaceutical Co., Ltd. | Drug for reducing side effects in ribavirin / interferon combination therapy |
JP2007501806A (ja) * | 2003-08-13 | 2007-02-01 | ハワード ジェイ. スミス アンド アソシエイツ ピーティーワイ エルティーディー | ウィルス感染を治療する方法 |
WO2005120479A1 (en) * | 2004-06-09 | 2005-12-22 | Gpc Biotech Ag | Use of selenium or a selenium salt and a retinoid acid or a retinoid in the treatment of viral hepatitis c |
US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
DE602007009377D1 (de) | 2006-05-30 | 2010-11-04 | Intarcia Therapeutics Inc | Zweiteiliger flussmodulator mit einem internen kanal für ein osmotisches ausgabesystem |
US7682356B2 (en) | 2006-08-09 | 2010-03-23 | Intarcia Therapeutics, Inc. | Osmotic delivery systems and piston assemblies for use therein |
JP5351884B2 (ja) | 2007-04-23 | 2013-11-27 | インターシア セラピューティクス,インコーポレイティド | インスリン分泌促進性ペプチドの懸濁製剤及び使用 |
CA2726861C (en) | 2008-02-13 | 2014-05-27 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
HUE035862T2 (en) | 2009-09-28 | 2018-05-28 | Intarcia Therapeutics Inc | Rapid development and / or completion of substantially steady-state drug delivery |
EA031737B1 (ru) | 2010-06-03 | 2019-02-28 | Фармасайкликс, Инк. | Применение ингибиторов тирозинкиназы брутона (btk) для лечения лейкоза и лимфомы |
US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
US20130129680A1 (en) * | 2011-11-23 | 2013-05-23 | Thomas Christian Lines | Method for treating hepatitis c virus infection using quercetin-containing compositions |
WO2014018567A1 (en) | 2012-07-24 | 2014-01-30 | Pharmacyclics, Inc. | Mutations associated with resistance to inhibitors of bruton's tyrosine kinase (btk) |
CA2890111A1 (en) | 2012-11-02 | 2014-05-08 | Pharmacyclics, Inc. | Tec family kinase inhibitor adjuvant therapy |
EP3119910A4 (en) | 2014-03-20 | 2018-02-21 | Pharmacyclics LLC | Phospholipase c gamma 2 and resistance associated mutations |
US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
ES2968262T3 (es) | 2015-06-03 | 2024-05-08 | I2O Therapeutics Inc | Sistemas de colocación de implantes |
WO2017200943A1 (en) | 2016-05-16 | 2017-11-23 | Intarcia Therapeutics, Inc. | Glucagon-receptor selective polypeptides and methods of use thereof |
USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
CN110225762A (zh) | 2017-01-03 | 2019-09-10 | 因塔西亚制药公司 | 包括glp-1受体激动剂的连续施用和药物的共同施用的方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU5157998A (en) * | 1996-11-01 | 1998-05-29 | Thomas Najarian | Methods and compositions for treatment of hepatitis c infection |
-
2000
- 2000-04-18 EP EP20000303246 patent/EP1046399A1/en not_active Withdrawn
- 2000-04-18 WO PCT/US2000/010240 patent/WO2000062799A1/en active Application Filing
- 2000-04-18 JP JP2000611935A patent/JP2002542202A/ja active Pending
- 2000-04-18 CO CO00028688A patent/CO5241354A1/es not_active Application Discontinuation
- 2000-04-18 BR BR0009840-0A patent/BR0009840A/pt not_active IP Right Cessation
- 2000-04-18 HU HU0200942A patent/HUP0200942A3/hu unknown
- 2000-04-18 AU AU44633/00A patent/AU4463300A/en not_active Abandoned
- 2000-04-18 CA CA002306039A patent/CA2306039A1/en not_active Abandoned
- 2000-04-18 CN CN00808831A patent/CN1355708A/zh active Pending
- 2000-04-18 AR ARP000101815A patent/AR023541A1/es unknown
- 2000-04-19 PE PE2000000373A patent/PE20010284A1/es not_active Application Discontinuation
- 2000-04-19 MX MXPA00003974A patent/MXPA00003974A/es unknown
-
2001
- 2001-10-18 NO NO20015059A patent/NO20015059L/no not_active Application Discontinuation
- 2001-10-18 ZA ZA200108571A patent/ZA200108571B/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU4463300A (en) | 2000-11-02 |
ZA200108571B (en) | 2003-01-20 |
CN1355708A (zh) | 2002-06-26 |
NO20015059D0 (no) | 2001-10-18 |
CA2306039A1 (en) | 2000-10-19 |
WO2000062799A1 (en) | 2000-10-26 |
HUP0200942A3 (en) | 2003-03-28 |
HUP0200942A2 (hu) | 2002-07-29 |
MXPA00003974A (es) | 2002-03-08 |
PE20010284A1 (es) | 2001-03-05 |
JP2002542202A (ja) | 2002-12-10 |
NO20015059L (no) | 2001-12-19 |
AR023541A1 (es) | 2002-09-04 |
CO5241354A1 (es) | 2003-01-31 |
EP1046399A1 (en) | 2000-10-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1925 DE 27/11/2007. |